Hailed as "unsinkable, " the "Kursk" was on maneuvers when mysterious explosions rocked the sub, causing it to sink to the bottom of the sea with its 118-man crew. This in-depth look at the disaster reveals previously unreleased information from family members of the deceased as well as from government officials.

    She explores the culture of genealogy buffs, the science of DNA, and the business of companies like Ancestry and 23andMe, all while tracing the story of one woman, her unusual results, and a relentless methodical drive for answers that becomes a thoroughly modern genetic detective story.

    Just a half century ago, this idea was revolutionary. In April 1953, James Watson and Francis Crick published in Nature their groundbreaking work revealing the double helix structure of DNA. While this discovery received wide attention from both mainstream media and the academic community, it was just one part of the bigger story in this history of molecular biology. By the mid-1950s, the scientific community confirmed that genes were indeed comprised of DNA; they just needed to crack the genetic code—and the race was on. Life’s Greatest Secret is the full and rich history of this challenge and the characters—many of whom were not biologists—whose work contributed to this grand scientific endeavor: mathematician and father of cybernetics Norbert Wiener, physicist Erwin Schrödinger, information theorist Claude Shannon, and biologists Jacques Monod and Marshall Nirenberg.In Life’s Greatest Secret, science historian and zoologist Matthew Cobb shows that the race to crack the genetic code was mostly a matter of craft—individuals or small groups struggling with ideas and concepts as much as they were with facts, trying to find the right experiment to answer the right questions, even if they didn’t know what the questions were, and finding that, even when the most definitive answer served mostly to reveal more ignorance, whether in 1953, with Watson and Crick, or in 1961, when Nirenberg and Matthaei showed how DNA codes for specific amino acids, and again and again thereafter, or in 2000, with the first publication of a human genome. Each discovery was a leap forward in our understanding of the natural world and our place within in, akin to the discoveries of Galileo and Einstein in the realm of physics, or the publication of Darwin’s On the Origin of Species. And each served to show how much bigger the problem was that anyone had previously imagined, a trend that continues, as Cobb shows, even today, whether we are discussing gene regulation, epigenetics, or GMOs.Life’s Greatest Secret is a story of ideas and of experimentation, of ingenuity, insight, and dead-ends, in the hunt to make the greatest discovery of twentieth century biology. Ultimately, though, this is a story of humans exploring what it is that makes us human.

    But, despite appearances, these are not dogs—they are foxes. They are the result of the most astonishing experiment in breeding ever undertaken—imagine speeding up thousands of years of evolution into a few decades. In 1959, biologists Dmitri Belyaev and Lyudmila Trut set out to do just that, by starting with a few dozen silver foxes from fox farms in the USSR and attempting to recreate the evolution of wolves into dogs in real time in order to witness the process of domestication. This is the extraordinary, untold story of this remarkable undertaking. Most accounts of the natural evolution of wolves place it over a span of about 15,000 years, but within a decade, Belyaev and Trut’s fox breeding experiments had resulted in puppy-like foxes with floppy ears, piebald spots, and curly tails. Along with these physical changes came genetic and behavioral changes, as well. The foxes were bred using selection criteria for tameness, and with each generation, they became increasingly interested in human companionship. Trut has been there the whole time, and has been the lead scientist on this work since Belyaev’s death in 1985, and with Lee Dugatkin, biologist and science writer, she tells the story of the adventure, science, politics, and love behind it all.  In How to Tame a Fox, Dugatkin and Trut take us inside this path-breaking experiment in the midst of the brutal winters of Siberia to reveal how scientific history is made and continues to be made today. To date, fifty-six generations of foxes have been domesticated, and we continue to learn significant lessons from them about the genetic and behavioral evolution of domesticated animals. How to Tame a Fox offers an incredible tale of scientists at work, while also celebrating the deep attachments that have brought humans and animals together throughout time.

    Darwin was only too aware of the storm his theory of evolution would provoke but he would surely have raised an incredulous eyebrow at the controversy still raging a century and a half later. Evolution is accepted as scientific fact by all reputable scientists and indeed theologians, yet millions of people continue to question its veracity.In The Greatest Show on Earth Richard Dawkins takes on creationists, including followers of ‘Intelligent Design’ and all those who question the fact of evolution through natural selection. Like a detective arriving on the scene of a crime, he sifts through fascinating layers of scientific facts and disciplines to build a cast-iron case: from the living examples of natural selection in birds and insects; the ‘time clocks’ of trees and radioactive dating that calibrate a timescale for evolution; the fossil record and the traces of our earliest ancestors; to confirmation from molecular biology and genetics. All of this, and much more, bears witness to the truth of evolution.The Greatest Show on Earth comes at a critical time: systematic opposition to the fact of evolution is now flourishing as never before, especially in America. In Britain and elsewhere in the world, teachers witness insidious attempts to undermine the status of science in their classrooms. Richard Dawkins provides unequivocal evidence that boldly and comprehensively rebuts such nonsense. At the same time he shares with us his palpable love of the natural world and the essential role that science plays in its interpretation. Written with elegance, wit and passion, it is hard-hitting, absorbing and totally convincing.

    The world of golf is at a crossroads. As tech­nological innovations displace traditional philosophies, the golfing community has splintered into two deeply combative factions: the old-school teachers and players who believe in feel, artistry, and imagination, and the technical minded who want to remake the game around data. In Golf’s Holy War, Brett Cyrgalis takes readers inside the heated battle playing out from weekend hackers to PGA Tour pros. At the Titleist Performance Institute in Oceanside, California, golfers clad in full-body sensors target weaknesses in their biomechanics, while others take part in mental exercises designed to test their brain’s psychological resilience. Meanwhile, coaches like Michael Hebron purge golfers of all technical infor­mation, tapping into the power of intuitive physical learning by playing rudimentary games. From historic St. Andrews to manicured Augusta, experimental com­munes in California to corporatized conferences in Orlando, William James to Ben Hogan to theoretical physics, the factions of the spiritual and technical push to redefine the boundaries of the game. And yet what does it say that Tiger Woods has orchestrated one of the greatest comebacks in sports history without the aid of a formal coach? But Golf’s Holy War is more than just a book about golf—it’s a story about modern life and how we are torn between resisting and embracing the changes brought about by the advancements of science and technology. It’s also an exploration of historical legacies, the enriching bonds of education, and the many interpretations of reality.

    This elegant, humane, and engaging book "captures what we know of the development of what makes us human" (Nature).Visit Armand Marie Leroi on the web: http: //armandleroi.com/index.htmlStepping effortlessly from myth to cutting-edge science,

    Their IQ scores, added together, totaled just 81. Following prevailing eugenic beliefs of the times, Skeels and his colleague Marie Skodak assumed that the girls had inherited their parents’ low intelligence and were therefore unfit for adoption. The girls were sent to an institution for the “feebleminded” to be cared for by “moron” women. To Skeels and Skodak’s astonishment, under the women’s care, the children’s IQ scores became normal.Now considered one of the most important scientific findings of the twentieth century, the discovery that environment shapes children’s intelligence was also one of the most fiercely contested—and its origin story has never been told. In The Orphans of Davenport, psychologist and esteemed historian Marilyn Brookwood chronicles how a band of young psychologists in 1930s Iowa shattered the nature-versus-nurture debate and overthrew long-accepted racist and classist views of childhood development.Transporting readers to a rural Iowa devastated by dust storms and economic collapse, Brookwood reveals just how profoundly unlikely it was for this breakthrough to come from the Iowa Child Welfare Research Station. Funded by the University of Iowa and the Rockefeller Foundation, and modeled on America’s experimental agricultural stations, the Iowa Station was virtually unknown, a backwater compared to the renowned psychology faculties of Stanford, Harvard, and Princeton. Despite the challenges they faced, the Iowa psychologists replicated increased intelligence in thirteen more “retarded” children.When Skeels published their incredible work, America’s leading psychologists—eugenicists all—attacked and condemned his conclusions. The loudest critic was Lewis M. Terman, who advocated for forced sterilization of low-intelligence women and whose own widely accepted IQ test was threatened by the Iowa research. Terman and his opponents insisted that intelligence was hereditary, and their prestige ensured that the research would be ignored for decades. Remarkably, it was not until the 1960s that a new generation of psychologists accepted environment’s role in intelligence and helped launch the modern field of developmental neuroscience..Drawing on prodigious archival research, Brookwood reclaims the Iowa researchers as intrepid heroes and movingly recounts the stories of the orphans themselves, many of whom later credited the psychologists with giving them the opportunity to forge successful lives. A radiant story of the power and promise of science to better the lives of us all, The Orphans of Davenport unearths an essential history at a moment when race science is dangerously resurgent.

    In the mid-1970s, scientists began using DNA sequences to reexamine the history of all life. Perhaps the most startling discovery to come out of this new field—the study of life’s diversity and relatedness at the molecular level—is horizontal gene transfer (HGT), or the movement of genes across species lines. It turns out that HGT has been widespread and important. For instance, we now know that roughly eight percent of the human genome arrived not through traditional inheritance from directly ancestral forms, but sideways by viral infection—a type of HGT.David Quammen chronicles these discoveries through the lives of the researchers who made them—such as Carl Woese, the most important little-known biologist of the twentieth century; Lynn Margulis, the notorious maverick whose wild ideas about “mosaic” creatures proved to be true; and Tsutomu Wantanabe, who discovered that the scourge of antibiotic-resistant bacteria is a direct result of horizontal gene transfer, bringing the deep study of genome histories to bear on a global crisis in public health.

    If you could bring back to life a person or animal, what would you choose? Pilcher highlights her own choices from eras gone, including the King of the Dinosaurs, Tyrannosaurus rex, and the King of Rock 'n' Roll, Elvis Presley.From dinosaurs to dodos and Neanderthals, BRING BACK THE KING reveals how the burgeoning field of DNA science is being used to help resurrect individual animals (did your beloved Fido die before siring offspring?) and entire species from their stony graves. Pilcher describes current initiatives and future plans to restore deceased animals, and uses both science and willful irreverence to assess the ramifications of how these genetic Lazaruses might fare in their brave new world. Could a pet dinosaur be trained to roll over? Would Neanderthals enjoy opera? Could a returning dodo seek vengeance upon humanity?Blending the very latest de-extinction technology with cloning, and hard-core popular science with levity, BRING BACK THE KING will generate a lot of thoughtful discussion and a chuckle or two.

    That scientist, David Hungerford, had no way of knowing that he had stumbled upon the starting point of modern cancer research—the Philadelphia chromosome. This book charts not only that landmark discovery, but also—for the first time, all in one place—the full sequence of scientific and medical discoveries that brought about the first-ever successful treatment of a lethal cancer at the genetic level.The significance of this mutant chromosome would take more than three decades to unravel; in 1990, it was recognized as the sole cause of a deadly blood cancer, chronic myeloid leukemia, or CML. This dramatic discovery launched a race involving doctors and researchers around the world, who recognized that in principle it might be possible to target CML at its genetic source.Science journalist Jessica Wapner brings extensive original reporting to this book, including interviews with more than thirty-five people with a direct role in this story. Wapner reconstructs more than forty years of crucial breakthroughs, clearly explains the science behind them, and pays tribute to the dozens of researchers, doctors, and patients whose curiosity and determination restored the promise of a future to the more than 70,000 people worldwide who are diagnosed with CML each year. Chief among them is researcher and oncologist Dr. Brian Druker, whose dedication to his patients fueled his quest to do everything within his power to save them.The Philadelphia Chromosome helps us to fully understand and appreciate just how pathbreaking, hard-won, and consequential are the achievements it recounts—and to understand the principles behind much of today’s most important cancer research, as doctors and scientists race to uncover and treat the genetic roots of a wide range of cancers.

    Putting people into places and situations unprecedented in history is stirred the imagination while the human experience was expanding and redefining. Yet, space exploration compels humans to confront a hostile environment of cosmic radiations, radical changes in the gravity and magnetic fields, as well as social isolation. Therefore, any space traveller is submitted to relevant health-related threats. In the twenty-first century, human space flight is poised to continue, but it will enjoy the ongoing developments in science and technology. It will become more networked, more global, and more oriented toward primary goals. A novel international human space flight policy could help achieve these objectives by clarifying the rationale, the ethics of acceptable risk, the role of remote presence, and the need for balance between funding and ambition to justify the risk of human lives. In order to address such a challenge, a preliminary careful survey of the available scientific data is mandatory to set forth adequate countermeasures. Envisaged solutions should provide a sound and technically feasible approach for counteracting microgravity and cosmic rays effects, which represent the main health risk for space crews. This objective must necessarily be sustained by national/international space agencies, which would coordinate their common efforts into a defined international spaceflight program.

    Evo Devo Evolutionary Developmental Biology is the new science that has finally cracked open the box. Within the pages of his rich and riveting book, Sean B. Carroll explains how we are discovering that complex life is ironically much simpler than anyone ever expected.

    But Neil Armstrong and Sally Ride would have never made history, and humankind would not have touched the stars, if not for the men and women on the ground who lit the fuse that launched the first rockets.Enthralled as a boy by the exploits of Flash Gordon and the novels of Robert Heinlein and Arthur C. Clarke—who put the science in science fiction—James French became one of the original unsung engineers of America’s groundbreaking space program. His fascinating memoir offers an up-close-and-technical look at building, testing, and perfecting the pioneering Saturn rockets and original lunar landing module, and he shares true tales, both humorous and harrowing, of life—and near death—on the front lines of scientific exploration.If you’ve ever said, “It’s not rocket science,” you’re right. It’s rocket engineering—and here’s your chance to marvel at how it changed the world and made it possible to explore all that lies beyond Earth. James R French graduated from MIT in 1958 with a degree of BSME Specializing in Propulsion. His first job was with Rocketdyne Division of North American Aviation where he worked on developmental testing of H-1 engines and combustion devices hardware for F-1 and J-2 engines used in Saturn 5. Mr. French has also worked at TRW Systems, where he was Lead Development Test Engineer on the Lunar Module Descent Engine, and Jet Propulsion Laboratory where he was Advanced Planetary studies Manager as well as Chief Engineer for the SP-100 Space Nuclear Power System and worked on Mariners 5, 6, 7, 8, and 9; Viking 1 & 2 and Voyager 1 & 2. . In 1986, he helped found American Rocket Co., a commercial launch company.Since 1987, Mr. French has been consultant to a variety of aerospace companies, SDIO, NASA, and USAF. He has participated in various startup companies in the private space flight arena and currently consults extensively to Blue Origin. Mr. French is co-author with Dr. Michael Griffin of the best-selling text Space Vehicle Design, published by AIAA. The second edition of the book has received the Summerfield Book Award for 2008. Mr. French is a Fellow of both AIAA and the British Interplanetary Society and a 50+ year member of AIAA. He has held several Technical Committee and other posts in AIAA. Cover design by Evan Twohy

    In this compelling study of true crime, Liverpool's most popular author Tom Slemen recounts some of the most intriguing and baffling murders of Merseyside such as:• The baffling case of the Victorian canned corpse• The magistrate's beautiful granddaughter who was killed by a crazed admirer• The condemned man who was hanged twice• Frederick Deeming - the Rainhill psychopath who wiped out his own family and danced on their grave with his next victim• The bizarre link between a South Seas cult and the housewife who was stabbed fourteen times in her Knotty Ash home by a killer who struck under the cover of a fog• The unsolved case of the superintendent and his son who died of gunshot wounds under mysterious circumstances - in a police station• The enigmatic murder of Julia Wallace - and a very credible solution• The only assassination of a British prime minister - by a Liverpool businessman Plus many more fascinating murder cases.This fascinating book is a must for all readers of true crime in general and Liverpudlians and Merseysiders in particular.