As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his co-discovery of the structure of DNA. She and her collaborators turned ​a curiosity ​of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020.

    Sixty-six million years ago, the Earth’s most fearsome creatures vanished. Today they remain one of our planet’s great mysteries. Now The Rise and Fall of the Dinosaurs reveals their extraordinary, 200-million-year-long story as never before.In this captivating narrative (enlivened with more than seventy original illustrations and photographs), Steve Brusatte, a young American paleontologist who has emerged as one of the foremost stars of the field—naming fifteen new species and leading groundbreaking scientific studies and fieldwork—masterfully tells the complete, surprising, and new history of the dinosaurs, drawing on cutting-edge science to dramatically bring to life their lost world and illuminate their enigmatic origins, spectacular flourishing, astonishing diversity, cataclysmic extinction, and startling living legacy. Captivating and revelatory, The Rise and Fall of the Dinosaurs is a book for the ages.Brusatte traces the evolution of dinosaurs from their inauspicious start as small shadow dwellers—themselves the beneficiaries of a mass extinction caused by volcanic eruptions at the beginning of the Triassic period—into the dominant array of species every wide-eyed child memorizes today, T. rex, Triceratops, Brontosaurus, and more. This gifted scientist and writer re-creates the dinosaurs’ peak during the Jurassic and Cretaceous, when thousands of species thrived, and winged and feathered dinosaurs, the prehistoric ancestors of modern birds, emerged. The story continues to the end of the Cretaceous period, when a giant asteroid or comet struck the planet and nearly every dinosaur species (but not all) died out, in the most extraordinary extinction event in earth’s history, one full of lessons for today as we confront a “sixth extinction.”Brusatte also recalls compelling stories from his globe-trotting expeditions during one of the most exciting eras in dinosaur research—which he calls “a new golden age of discovery”—and offers thrilling accounts of some of the remarkable findings he and his colleagues have made, including primitive human-sized tyrannosaurs; monstrous carnivores even larger than T. rex; and paradigm-shifting feathered raptors from China.An electrifying scientific history that unearths the dinosaurs’ epic saga, The Rise and Fall of the Dinosaurs will be a definitive and treasured account for decades to come.

    In The Ends of the World, Peter Brannen dives into deep time, exploring Earth’s past dead ends, and in the process, offers us a glimpse of our possible future.Many scientists now believe that the climate shifts of the twenty-first century have analogs in these five extinctions. Using the visible clues these devastations have left behind in the fossil record, The Ends of the World takes us inside “scenes of the crime,” from South Africa to the New York Palisades, to tell the story of each extinction. Brannen examines the fossil record—which is rife with creatures like dragonflies the size of sea gulls and guillotine-mouthed fish—and introduces us to the researchers on the front lines who, using the forensic tools of modern science, are piecing together what really happened at the crime scenes of the Earth’s biggest whodunits.Part road trip, part history, and part cautionary tale, The Ends of the World takes us on a tour of the ways that our planet has clawed itself back from the grave, and casts our future in a completely new light.

    Beginning with the study of DNA in Egyptian mummies in the early 1980s and culminating in the sequencing of the Neanderthal genome in 2010, Neanderthal Man describes the events, intrigues, failures, and triumphs of these scientifically rich years through the lens of the pioneer and inventor of the field of ancient DNA.We learn that Neanderthal genes offer a unique window into the lives of our hominin relatives and may hold the key to unlocking the mystery of why humans survived while Neanderthals went extinct. Drawing on genetic and fossil clues, Pääbo explores what is known about the origin of modern humans and their relationship to the Neanderthals and describes the fierce debate surrounding the nature of the two species’ interactions. His findings have not only redrawn our family tree, but recast the fundamentals of human history—the biological beginnings of fully modern Homo sapiens, the direct ancestors of all people alive today.A riveting story about a visionary researcher and the nature of scientific inquiry, Neanderthal Man offers rich insight into the fundamental question of who we are.

    Maybe it's made of silicon! Maybe it has wheels! Or maybe it doesn't. In The Equations of Life, biologist Charles S. Cockell makes the forceful argument that the laws of physics narrowly constrain how life can evolve, making evolution's outcomes predictable. If we were to find on a distant planet something very much like a lady bug eating something like an aphid, we shouldn't be surprised. The forms of life are guided by a limited set of rules, and as a result, there is a narrow set of solutions to the challenges of existence.A remarkable scientific contribution breathing new life into Darwin's theory of evolution, The Equations of Life makes a radical argument about what life can -- and can't -- be.

    Many people think of microbes as germs to be eradicated, but those that live with us—the microbiome—build our bodies, protect our health, shape our identities, and grant us incredible abilities. In this astonishing book, Ed Yong takes us on a grand tour through our microbial partners, and introduces us to the scientists on the front lines of discovery. Yong, whose humor is as evident as his erudition, prompts us to look at ourselves and our animal companions in a new light—less as individuals and more as the interconnected, interdependent multitudes we assuredly are. The microbes in our bodies are part of our immune systems and protect us from disease. Those in cows and termites digest the plants they eat. In the deep oceans, mysterious creatures without mouths or guts depend on microbes for all their energy. Bacteria provide squids with invisibility cloaks, help beetles to bring down forests, and allow worms to cause diseases that afflict millions of people. I Contain Multitudes is the story of these extraordinary partnerships, between the creatures we are familiar with and those we are not. It reveals how we humans are disrupting these partnerships and how we might manipulate them for our own good. It will change both our view of nature and our sense of where we belong in it.

    In this thrill-ride across millennia and continents, the complete history of the planet comes to life: from the Earth's fiery birth to its near-obliteration in the Triassic period, and from the first signs of human life to the tentative future of a world with a burgeoning population and a global warming crisis. Covering a wide range of topics including astrophysics, zoology, and sociology, and complete with maps and illustrations, What on Earth Happened? In Brief is the endlessly entertaining story of the planet, life, and people.

    They were hunter-gatherers, consummate foraging experts, but taking the world as they found it. Then a revolution occurred – our ancestors’ interaction with other species changed. They began to tame them. The human population boomed; civilization began.In her new book, Tamed, Alice Roberts uncovers the amazing deep history of ten familiar species with incredible wild pasts: dogs, apples and wheat; cattle; potatoes and chickens; rice, maize, and horses – and, finally, humans. Alice Roberts not only reveals how becoming part of our world changed these animals and plants, but shows how they became our allies, essential to the survival and success of our own species – and to our future.Enlightening, wide-ranging and endlessly fascinating, Tamed is an epic story, encompassing hundreds of thousands of years of history and archaeology alongside cutting-edge genetics and anthropology. Yet it is also a deeply personal journey that will change how we see ourselves and the species on which we have left our mark.

    In the great halls of science, dogma holds that Darwin's theory of natural selection explains every branch on the tree of life: which species thrive, which wither away to extinction, and what features each evolves. But can adaptation by natural selection really account for everything we see in nature? Yale University ornithologist Richard Prum--reviving Darwin's own views--thinks not. Deep in tropical jungles around the world are birds with a dizzying array of appearances and mating displays: Club-winged Manakins who sing with their wings, Great Argus Pheasants who dazzle prospective mates with a four-foot-wide cone of feathers covered in golden 3D spheres, Red-capped Manakins who moonwalk. In thirty years of fieldwork, Prum has seen numerous display traits that seem disconnected from, if not outright contrary to, selection for individual survival. To explain this, he dusts off Darwin's long-neglected theory of sexual selection in which the act of choosing a mate for purely aesthetic reasons--for the mere pleasure of it--is an independent engine of evolutionary change. Mate choice can drive ornamental traits from the constraints of adaptive evolution, allowing them to grow ever more elaborate. It also sets the stakes for sexual conflict, in which the sexual autonomy of the female evolves in response to male sexual control. Most crucially, this framework provides important insights into the evolution of human sexuality, particularly the ways in which female preferences have changed male bodies, and even maleness itself, through evolutionary time. The Evolution of Beauty presents a unique scientific vision for how nature's splendor contributes to a more complete understanding of evolution and of ourselves.

    In the mid-1970s, scientists began using DNA sequences to reexamine the history of all life. Perhaps the most startling discovery to come out of this new field—the study of life’s diversity and relatedness at the molecular level—is horizontal gene transfer (HGT), or the movement of genes across species lines. It turns out that HGT has been widespread and important. For instance, we now know that roughly eight percent of the human genome arrived not through traditional inheritance from directly ancestral forms, but sideways by viral infection—a type of HGT.David Quammen chronicles these discoveries through the lives of the researchers who made them—such as Carl Woese, the most important little-known biologist of the twentieth century; Lynn Margulis, the notorious maverick whose wild ideas about “mosaic” creatures proved to be true; and Tsutomu Wantanabe, who discovered that the scourge of antibiotic-resistant bacteria is a direct result of horizontal gene transfer, bringing the deep study of genome histories to bear on a global crisis in public health.

    This book will show you how to refine your testing skills as an Electrician or Technician using all the best testing methods!! Now in a new revised edition filled with new illustrations and explanation!! Here Is A Preview Of What You'll Learn... Chapter 1: Important Things To Remember Before Starting Diagnosis Chapter 2: Voltage Testing Like a Pro Chapter 3: Open Circuit Testing Chapter 4: Resistance Problem Testing Using The Voltmeter Chapter 5: Miscellaneous Electrical Tricks And Diagnostic Tips &Much, much more! Download Your Copy Today! And You Too Can Get Started In Testing Electrical Circuit Like A Pro!! Read on your PC, Mac, smart phone, tablet or Kindle device. Last Revised (8/29/2017) Important Note When Purchasing My Books!! I am constantly updating and adding new content to all my books based off of customer comments & requests. To get the latest version after purchase please go to [Your Account] on the top right of the Amazon homepage. then click [Manage Your Content And Devices], then go to [Setting] and please turn ON your [Automatic Book Updates]. This will allow you to get the latest revised edition after the initial purchase for free . Thank you. (: Tags. Electrical Troubleshooting How to Diagnosis Diagnostics Beginner Electronics Automotive Motorcycle Testing Industrial Household Electric Aviation Circuit Voltmeter Multimeter Tools

    A major Manchester gangster called Tommy McKinlay is on remand and it looks as though he will be going away for a long stretch. But he knows something that DCI Miller can't possibly afford to be made public. Something about the infamous "Pop" case from three years earlier. Something that could see Miller behind bars, for a very long time. It was supposed to be a very closely guarded secret. As far as Miller was aware, only a handful of people knew the details which are now threatening to destroy his career, and his life. What does McKinlay want in return for his silence? More importantly, can McKinlay be trusted to keep this explosive information silent if Miller agrees to his demands? Twisting the Truth is a heart-stopping DCI Miller page-turner which promises to keep readers guessing until the very last page. Can Miller get out of this? Or is Tommy McKinlay going to be Miller's puppet-master for the rest of time? Will Miller manage to keep his team together as the gravity of the situation rocks his officers who also face disgrace and prison time if McKinlay's information ever became public? This is a very deep hole that Manchester's best known detective has found himself in, one which threatens everything. Twisting the Truth will be released on May 18th. It is advisable to read the first DCI Miller story: One Man Crusade, in order to fully enjoy this nail-biting thriller. Twisting the Truth is the 8th DCI Miller adventure and is a sequel to Miller 1: One Man Crusade. Miller 1 is "One Man Crusade" Miller 2 is "Neighbours From Hell" Miller 3 is "Road To Nowhere" Miller 4 is "Gone Too Far" Miller 5 is "The Final Cut" Miller 6 is "Proof of Life" Miller 7 is "Nothing to Lose" WARNING, Contains frequent bad language, including the worst one a few times. Please do not purchase if offended by swearing. On Amazon's "customers also bought" function, Steven Suttie's books are ranked alongside titles by Ian Rankin, Val McDermid, Kerry Wilkinson, Ben Cheetham, Martina Cole, Karen Woods, Paul Finch, Heather Burnside, Rachel Abbott, Kimberley Chambers, Anna Smith, David Menon, Ed James, Robin Roughley. Lisa Hartley, D.S. Butler, Helen Durrant, RC Bridgestock, Col Bury, Lisa Hall, Pam Howes, Iain Cameron, Jessie Keane, Val McDermid, Adam Croft, P.F Ford, Matt Brolly, Mel Sherratt, Angela Clarke, Leigh Russell, Derek Fee, Janice Frost, Paul Gitsham, Steven Dunne, Katherine Pathak, Oliver Tidy, T.M.E Walsh, Peter Grainger, Dave Sivers, Tony Black, Mike Craven, Peter Grainger, Angie Smith, Stephen Puleston, Michael Murray, Angela Marsons, Mark Edwards, LJ Ross, Kathryn Croft, Graham Masterton, Caroline Mitchell, Nick Alexander, CL Taylor, Louise Voss, Jenny Blackhurst, Marnie Riches, Michael Wood, Luca Veste, Damien Boyd, Paula Hawkins, Lynwood Barclay, Ann Cleeves, M.A. Comley, Mark Sennen, Tara Lyons, Louise Voss, Squid McFinnigan, Rob Sinclair, Jane Isaac, Nicky Black, Faith Mortimer, Dreda Say Mitchell, Michael Kerr, Stephen Edger, John Nicholl, Ruth Dugdall, Robert Bryndza, B.A. Paris, Katerina Diamond, Maggie James, Lisa Hall, Georgie Logan, Tammy Robinson and Linda Tweedie

    It intersects with Darwin’s theory of evolution, and collides with the horrors of Nazi eugenics in the 1940s. The gene transforms post-war biology. It reorganizes our understanding of sexuality, temperament, choice and free will. This is a story driven by human ingenuity and obsessive minds – from Charles Darwin and Gregor Mendel to Francis Crick, James Watson and Rosalind Franklin, and the thousands of scientists still working to understand the code of codes.This is an epic, moving history of a scientific idea coming to life, by the author of The Emperor of All Maladies. But woven through The Gene, like a red line, is also an intimate history – the story of Mukherjee’s own family and its recurring pattern of mental illness, reminding us that genetics is vitally relevant to everyday lives. These concerns reverberate even more urgently today as we learn to “read” and “write” the human genome – unleashing the potential to change the fates and identities of our children.Majestic in its ambition, and unflinching in its honesty, The Gene gives us a definitive account of the fundamental unit of heredity – and a vision of both humanity’s past and future.

    MacNeill examines the surprising - and sometimes unsettling - answers to this most basic of human questions. The remarkable new field of evolutionary psychology takes a scientific approach to the evolution of human nature. Analyzing human behavior in relation to food, clothing, shelter, health care, and sex, Evolutionary Psychology proves an immensely stimulating exploration of human endeavor.

    But, despite appearances, these are not dogs—they are foxes. They are the result of the most astonishing experiment in breeding ever undertaken—imagine speeding up thousands of years of evolution into a few decades. In 1959, biologists Dmitri Belyaev and Lyudmila Trut set out to do just that, by starting with a few dozen silver foxes from fox farms in the USSR and attempting to recreate the evolution of wolves into dogs in real time in order to witness the process of domestication. This is the extraordinary, untold story of this remarkable undertaking. Most accounts of the natural evolution of wolves place it over a span of about 15,000 years, but within a decade, Belyaev and Trut’s fox breeding experiments had resulted in puppy-like foxes with floppy ears, piebald spots, and curly tails. Along with these physical changes came genetic and behavioral changes, as well. The foxes were bred using selection criteria for tameness, and with each generation, they became increasingly interested in human companionship. Trut has been there the whole time, and has been the lead scientist on this work since Belyaev’s death in 1985, and with Lee Dugatkin, biologist and science writer, she tells the story of the adventure, science, politics, and love behind it all.  In How to Tame a Fox, Dugatkin and Trut take us inside this path-breaking experiment in the midst of the brutal winters of Siberia to reveal how scientific history is made and continues to be made today. To date, fifty-six generations of foxes have been domesticated, and we continue to learn significant lessons from them about the genetic and behavioral evolution of domesticated animals. How to Tame a Fox offers an incredible tale of scientists at work, while also celebrating the deep attachments that have brought humans and animals together throughout time.