From distressed small communities in Central Appalachia to wealthy suburbs; from disparate cities to once-idyllic farm towns; it's a heartbreaking trajectory that illustrates how this national crisis has persisted for so long and become so firmly entrenched. Beginning with a single dealer who lands in a small Virginia town and sets about turning high school football stars into heroin overdose statistics, Macy endeavors to answer a grieving mother's question-why her only son died-and comes away with a harrowing story of greed and need. From the introduction of OxyContin in 1996, Macy parses how America embraced a medical culture where overtreatment with painkillers became the norm. In some of the same distressed communities featured in her bestselling book Factory Man, the unemployed use painkillers both to numb the pain of joblessness and pay their bills, while privileged teens trade pills in cul-de-sacs, and even high school standouts fall prey to prostitution, jail, and death.Through unsparing, yet deeply human portraits of the families and first responders struggling to ameliorate this epidemic, each facet of the crisis comes into focus. In these politically fragmented times, Beth Macy shows, astonishingly, that the only thing that unites Americans across geographic and class lines is opioid drug abuse. But in a country unable to provide basic healthcare for all, Macy still finds reason to hope-and signs of the spirit and tenacity necessary in those facing addiction to build a better future for themselves and their families.

    But we should--even those of us who take care of our business in pristine, sanitary conditions. For it's not only in developing countries that human waste is a major public health threat: population growth is taxing even the most advanced sewage systems, and the disease spread by waste kills more people worldwide every year than any other single cause of death. Even in America, 1.95 million people have no access to an indoor toilet. Yet the subject remains unmentionable."The Big Necessity "takes aim at the taboo, revealing everything that matters about how people do--and don't--deal with their own waste. Moving from the deep underground sewers of Paris, London, and New York--an infrastructure disaster waiting to happen--to an Indian slum where ten toilets are shared by 60,000 people, Rose George stops along the way to explore the potential saviors: China's five million biogas digesters, which produce energy from waste; the heroes of third world sanitation movements; the inventor of the humble Car Loo; and the U.S. Army's personal lasers used by soldiers to zap their feces in the field.With razor-sharp wit and crusading urgency, mixing levity with gravity, Rose George has turned the subject we like to avoid into a cause with the most serious of consequences.

    After World War II, Don's work with the Air Force brought them to Colorado, where their twelve children perfectly spanned the baby boom: the oldest born in 1945, the youngest in 1965. In those years, there was an established script for a family like the Galvins—aspiration, hard work, upward mobility, domestic harmony—and they worked hard to play their parts. But behind the scenes was a different story: psychological breakdown, sudden shocking violence, hidden abuse. By the mid-1970s, six of the ten Galvin boys, one after another, were diagnosed as schizophrenic. How could all this happen to one family?What took place inside the house on Hidden Valley Road was so extraordinary that the Galvins became one of the first families to be studied by the National Institute of Mental Health. Their story offers a shadow history of the science of schizophrenia, from the era of institutionalization, lobotomy, and the schizophrenogenic mother to the search for genetic markers for the disease, always amid profound disagreements about the nature of the illness itself. And unbeknownst to the Galvins, samples of their DNA informed decades of genetic research that continues today, offering paths to treatment, prediction, and even eradication of the disease for future generations.With clarity and compassion, bestselling and award-winning author Robert Kolker uncovers one family's unforgettable legacy of suffering, love, and hope.

    But the historic landfall of October 1492 was only a secondary event of the year. The preceding January, they had accepted the surrender of Muslim Granada, ending centuries of Islamic rule in their peninsula. And later that year, they had ordered the expulsion or forced baptism of Spain's Jewish minority, a cruel crusade undertaken in an excess of zeal for their Catholic faith. Europe, in the century of Ferdinand and Isabella, was also awakening to the glories of a new age, the Renaissance, and the Spain of the "Catholic Kings" - as Ferdinand and Isabella came to be known - was not untouched by this brilliant revival of learning. Here, from the noted historian Malveena McKendrick, is their remarkable story.

    It's not that she's an outcast (she might even be your friend or your wife, or your mother) so much as she's a social variable. Sometimes, she's the life of the party; others, she's the center of gossip. She's the unruly woman, and she's one of the most provocative, powerful forms of womanhood today. There have been unruly women for as long as there have been boundaries of what constitutes acceptable "feminine" behavior, but there's evidence that she's on the rise--more visible and less easily dismissed--than ever before. In Too Fat, Too Slutty, Too Loud, Anne Helen Petersen uses the lens of "unruliness" to explore the ascension of eleven contemporary powerhouses: Serena Williams, Melissa McCarthy, Abbi Jacobson, Ilana Glazer, Nicki Minaj, Kim Kardashian, Hillary Clinton, Caitlyn Jenner, Jennifer Weiner, and Lena Dunham. Petersen explores why the public loves to love (and hate) these controversial figures, each of whom has been conceived as "too" something: too queer, too strong, too honest, too old, too pregnant, too shrill, too much. With its brisk, incisive analysis, Too Fat, Too Slutty, Too Loud will be a conversation-starting book on what makes and breaks celebrity today.

    Authors Barbara Ehrenreich and Deirdre English have never lost faith in science itself, but insist that we hold those who interpret it to higher standards. Women are entering the medical and scientific professions in greater numbers but as recent research shows, experts continue to use pseudoscience to tell women how to live. This edition of For Her Own Good provides today's readers with an indispensable dose of informed skepticism.

    The late-night passing of a beloved aunt summons a childhood bully who shows up minutes later, after twenty-five years, to be forgiven and to heal a broken doctor. This ER doctor finds God's opposite in: a battered child's bruises covered over by make-up, a dying patient whose son finally shows up at the end to reclaim the man's high-top sneakers, the rich or celebrity patients loaded with prescription drugs from doctor friends who end up addicted. But, his real outrage is directed at our cavalier treatment of the elderly, If you put a G-tube in your 80-year-old mother with Alzheimer's because she's no longer eating, you will probably have a fast track to hell.

    Somewhere between the exhilarating rise of Girl Power in the 1990s and today, the pursuit of physical perfection has been recast as the source of female empowerment. And commercialization has spread the message faster and farther, reaching girls at ever-younger ages. But how dangerous is pink and pretty, anyway? Being a princess is just make-believe; eventually they grow out of it . . . or do they?In search of answers, Peggy Orenstein visited Disneyland, trolled American Girl Place, and met parents of beauty-pageant preschoolers tricked out like Vegas showgirls. The stakes turn out to be higher than she ever imagined. From premature sexualization to the risk of depression to rising rates of narcissism, the potential negative impact of this new girlie-girl culture is undeniable—yet armed with awareness and recognition, parents can effectively counterbalance its influence in their daughters' lives.

    When attorney Chris Hansen learned that the U.S. government was issuing patents for human genes to biotech companies, his first thought was, How can a corporation own what makes us who we are? Then he discovered that women were being charged exorbitant fees to test for hereditary breast and ovarian cancers, tests they desperately needed—all because Myriad Genetics had patented the famous BRCA genes. So he sued them. Jorge L. Contreras, one of the nation’s foremost authorities on human genetics law, has devoted years to investigating the groundbreaking civil rights case known as AMP v. Myriad. In The Genome Defense Contreras gives us the view from inside as Hansen and his team of ACLU lawyers, along with a committed group of activists, scientists, and physicians, take their one-in-a-million case all the way to the U.S. Supreme Court. Contreras interviewed more than a hundred key players involved in all aspects of the case—from judges and policy makers to ethicists and genetic counselors, as well as cancer survivors and those whose lives would be impacted by the decision—expertly weaving together their stories into a fascinating narrative of this pivotal moment in history.  The Genome Defense is a powerful and compelling story about how society must balance scientific discovery with corporate profits and the rights of all people.

    The media seized hold of the story and, in the process, helped to launch one of the most devastating health scares ever. In the years to come Wakefield would be revealed as a profiteer in league with class-action lawyers, and he would eventually lose his medical license. Meanwhile, one study after another failed to find any link between childhood vaccines and autism. Yet the myth that vaccines somehow cause developmental disorders lives on. Despite the lack of corroborating evidence, it has been popularized by media personalities such as Oprah Winfrey and Jenny McCarthy and legitimized by journalists who claim that they are just being fair to “both sides” of an issue about which there is little debate. Meanwhile, millions of dollars have been diverted from potential breakthroughs in autism research; families have spent their savings on ineffective “miracle cures"; and declining vaccination rates have led to outbreaks of deadly illnesses like Hib, measles, and whooping cough. Most tragic of all is the increasing number of children dying from vaccine-preventable diseases. In The Panic Virus Seth Mnookin draws on interviews with parents, public-health advocates, scientists, and anti-vaccine activists to tackle a fundamental question: How do we decide what the truth is? The fascinating answer helps explain everything from the persistence of conspiracy theories about 9/11 to the appeal of talk-show hosts who demand that President Obama “prove” he was born in America. The Panic Virus is the ultimate cautionary tale for our time.

    But in the inevitable condition of aging and death, the goals of medicine seem too frequently to run counter to the interest of the human spirit. Nursing homes, preoccupied with safety, pin patients into railed beds and wheelchairs. Hospitals isolate the dying, checking for vital signs long after the goals of cure have become moot. Doctors, committed to extending life, continue to carry out devastating procedures that in the end extend suffering.Gawande, a practicing surgeon, addresses his profession's ultimate limitation, arguing that quality of life is the desired goal for patients and families. Gawande offers examples of freer, more socially fulfilling models for assisting the infirm and dependent elderly, and he explores the varieties of hospice care to demonstrate that a person's last weeks or months may be rich and dignified.

     She’s Britney Spears shaving her head, Whitney Houston saying, “crack is whack,” and Amy Winehouse, dying in front of millions. But the trainwreck is also as old (and as meaningful) as feminism itself. From Mary Wollstonecraft—who, for decades after her death, was more famous for her illegitimate child and suicide attempts than for A Vindication of the Rights of Woman—to Charlotte Brontë, Billie Holiday, Sylvia Plath, and even Hillary Clinton, Sady Doyle’s Trainwreck dissects a centuries-old phenomenon and asks what it means now, in a time when we have unprecedented access to celebrities and civilians alike, and when women are pushing harder than ever against the boundaries of what it means to “behave.” Where did these women come from? What are their crimes? And what does it mean for the rest of us? For an age when any form of self-expression can be the one that ends you, Sady Doyle’s book is as fierce and intelligent as it is funny and compassionate—an essential, timely, feminist anatomy of the female trainwreck.

    Traversing the country, he encounters a pompous Western businessman swindling his way to millions, a local vendor with a flair for painting nudes, and long ago legends of a western circus. Sensitively written and expertly researched, Greetings from Myanmar: Exploring the Price of Progress in One of the Last Countries on Earth to Open for Business is the story of a flourishing nation still very much in limbo and an answer to the hard questions that arise when tourism not only charts, but shapes a place as well.

    For months Kantor and Twohey had been having confidential discussions with top actresses, former Weinstein employees and other sources, learning of disturbing long-buried allegations, some of which had been covered up by onerous legal settlements. The journalists meticulously picked their way through a web of decades-old secret payouts and nondisclosure agreements, pressed some of the most famous women in the world--and some unknown ones--to risk going on the record, and faced down Weinstein, his team of high-priced defenders, and even his private investigators. But nothing could have prepared them for what followed the publication of their Weinstein story. Within days, a veritable Pandora's Box of sexual harassment and abuse was opened, and women who had suffered in silence for generations began coming forward, trusting that the world would understand their stories. Over the next twelve months, hundreds of men from every walk of life and industry would be outed for mistreating their colleagues. But did too much change--or not enough? Those questions plunged the two journalists into a new phase of reporting and some of their most startling findings yet. With superlative detail, insight, and journalistic expertise, Kantor and Twohey take us for the first time into the very heart of this social shift, reliving in real-time what it took to get the story and giving an up-close portrait of the forces that hindered and spurred change. They describe the surprising journeys of those who spoke up--for the sake of other women, for future generations, and for themselves--and so changed us all.

    A number of studies show a link between vitamin K2, bone health and heart health. Is vitamin K2 a nutrient you need more of in your diet? As physicians, we feel everyone needs to be aware of the role this vitamin plays in health and wellness. This concise ebook explores the link between vitamin K2 and how it may protect against some of the most common diseases you’re at risk for as you age. Here are some of the questions this book will answer: The Role of Vitamin K in Your Body How Vitamin K2 Differs from Vitamin K1 and Why Most People Don’t Get Enough of It The Various Isoforms of Vitamin K2 and Which Ones Are Most Important for Health The Role Vitamin K2 Plays in Bone Health and Osteoporosis Prevention Vitamin K2 and Heart Disease: Can It Lower Your Risk or Even Reverse Atherosclerosis? Do You Need a Vitamin K2 Supplement? Vitamin K2 and Cancer: Is There a Link? The Role Vitamin K2 Plays in Dental Health Are You at Risk for Vitamin K Deficiency? Can You Get Enough Vitamin K2 Through Diet Alone? The Best Dietary Source of Vitamin K2 Why You Must Have Vitamin K2 if You Take a Vitamin D Supplement Are There Risks to Taking a Vitamin K2 Supplement? One Type of Vitamin K2 Supplement Source You Should Avoid You should have a better understanding of the health benefits of vitamin K2 once you finish.