Until now, the relatively slow speed of marketplace evolution has allowed wasteful habits to continue without consequence. This reality is ending. Detonate explains how organizations built up bad habits, identifies which ones masquerade as "best practices," and suggests alternatives that can contribute to winning in the marketplace. With a focus on optimism and empowerment, it focuses on an approach and mindset which are critical to successfully compete in an era characterized by profound technological advances and uncertainty.  •    Core themes challenge how you think about and approach problems •    Case studies illustrate the challenges you face and how to overcome them •    Recommendations are pragmatic and steer clear of suggesting a brand-new, complicated wiring diagram •    Actionable advice provides the first steps down an evolutionary pathIf you want to compete differently in today’s marketplace and to challenge the things your company does which you have a nagging feeling are actually just a waste of time – and maybe value-destroying – Detonate gives you what you need to ignite change.

    It can be microscopic, yet also accounts for the largest organisms ever recorded, living for millennia and weighing tens of thousands of tonnes. Its ability to digest rock enabled the first life on land, it can survive unprotected in space, and thrives amidst nuclear radiation.In this captivating adventure, Merlin Sheldrake explores the spectacular and neglected world of fungi: endlessly surprising organisms that sustain nearly all living systems. They can solve problems without a brain, stretching traditional definitions of ‘intelligence’, and can manipulate animal behaviour with devastating precision. In giving us bread, alcohol and life-saving medicines, fungi have shaped human history, and their psychedelic properties, which have influenced societies since antiquity, have recently been shown to alleviate a number of mental illnesses. The ability of fungi to digest plastic, explosives, pesticides and crude oil is being harnessed in break-through technologies, and the discovery that they connect plants in underground networks, the ‘Wood Wide Web’, is transforming the way we understand ecosystems. Yet they live their lives largely out of sight, and over ninety percent of their species remain undocumented.Entangled Life is a mind-altering journey into this hidden kingdom of life, and shows that fungi are key to understanding the planet on which we live, and the ways we think, feel and behave. The more we learn about fungi, the less makes sense without them.

    Where do you look for information when transferring a patient from one drug to another? Where do you find a clear overview when dealing with a complex patient (e.g, with co-morbid epilepsy or liver disease or HIV infection)? Where can you seek advice on prescribing psychotropics during pregnancy? "The Maudsley Prescribing Guidelines in Psychiatry"! The leading clinical reference for handling prescribing problems as encountered in daily practice and for formulating prescribing policy.Evidence-based and written by expertsThis book is the essential guide for anyone responsible for prescribing, dispensing or administering drugs for patients with mental health disorders. All the evidence has been reviewed and summarized succinctly by an expert team of psychiatrists and pharmacists.New content and improved formatThis new edition makes greater use of tables and boxes to facilitate quick reference and includes new sections on cytochrome-mediated interactions and psychiatric side effects of non-psychotropic drugs.Clinically relevantChapters address plasma monitoring, schizophrenia, bipolar disorder, depression and anxiety, children and adolescents, substance abuse and special patient groups. Each section has a full reference list. The book covers prescribing drugs outside their licensed indications and their interaction with substances such as alcohol, nicotine and caffeine.Useful for all levels of experienceTrainees will gain important information regarding the rational, safe and effective use of medications for patients with mental illness. Experienced clinicians will find excellent guidance regarding more complex issues that they may not encounter regularly.Why the Maudsley Prescribing Guidelines in Psychiatry?Long recognized as an international trailblazer in mental health care, the Maudsley Hospital earned its reputation for excellence in both in-patient and community care. It is highly regarded for its research, and pioneered the use of clinical neuroscience. You can trust "The Maudsley Prescribing Guidelines in Psychiatry" to be scientifically sound and clinically effective.