They are the powerhouses of our cells, essential for the production and management of energy at cell level. Dr Sarah Myhill, together with Dr John McLaren Howard of Acumen Laboratories and Dr Norman Booth of Mansfield College Oxford, has spent many years studying the relationship between their malfunction and the commonest problem seen by GPs in the UK – fatigue. Their research findings have been published in three scientific papers in the International Journal of Clinical and Experimental Medicine, in 2009, 2012 and 2013. These studies showed that poor functioning of the mitochondria is the central problem in CFS. Patients with the worst mitochondrial function had the worst fatigue and vice versa. This is solid scientific evidence that CFS is a problem with mitochondria and has allowed the objective measurement of fatigue for the first time. With the publication of the third study, which showed that mitochondrial function tests and symptoms improved in patients who took measures to address their mitochondrial problems, Dr Myhill was ready to write this book. Here she explains the importance of healthy mitochondria, how we can measure their functioning and what we can do to keep them healthy, or restore them to health if problems arise. CFS is all in our cells, not in our minds!

    David Peat explains the development and meaning of this Superstring Theory in a thoroughly readable, dramatic manner accessible to lay readers with no knowledge of mathematics. The consequences of the Superstring Theory are nothing less than astonishing.

    With a hundred dollars in his pocket, a beat up cavalry saddle, and a faraway look in his eye, John Egenes saddled his horse Gizmo and started down the trail on an adventure across the North American continent. Their seven month journey took them across 11 states from California to Virginia, ocean to ocean.. As they left the pressing confinement of the city behind them, the pair experienced the isolation and loneliness of the southwestern deserts, the vastness of the prairie, and the great landscapes that make up America. Across hundreds of miles of empty land they slept with coyotes and wild horses under the stars, and in urban areas they camped alone in graveyards and abandoned shacks. Along the way John and Gizmo were transformed from inexperienced horse and rider to veterans of the trail. With his young horse as his spiritual guide John slowly began to comprehend his own place in the world and to find peace within himself. Full of heart and humor, Egenes serves up a tale that's as big as the America he witnessed, an America that no longer exists. It was a journey that could only have been experienced step by step, mile by mile, from the view between a horse's ears.

    Today, says Dale Purves, the dominant research agenda may have taken us as far as it can--and neuroscientists may be approaching a paradigm shift. In this highly personal book, Purves reveals how we got to this point and offers his notion of where neuroscience may be headed next. Purves guides you through a half-century of the most influential ideas in neuroscience and introduces the extraordinary scientists and physicians who created and tested them. Purves offers a critical assessment of the paths that neuroscience research has taken, their successes and their limitations, and then introduces an alternative approach for thinking about brains. Building on new research on visual perception, he shows why common ideas about brain networks can't be right and uncovers the factors that determine our subjective experience. The resulting insights offer a deeper understanding of what it means to be human. - Why we need a better conception of what brains are trying to do and how they do it Approaches to understanding the brain over the past several decades may be at an impasse - The surprising lessons that can be learned from what we see How complex neural processes owe more to trial-and-error experience than to logical principles - Brains--and the people who think about them Meet some of the extraordinary individuals who've shaped neuroscience - The -ghost in the machine- problem The ideas presented further undermine the concept of free will

    Thanks largely to YouTube clips posted by the sloth orphanage in Costa Rica, sloths have attracted a vast audience of admirers. Instead of seeing them as ridiculous anachronisms of which we know little, they have turned into creatures considered by many to be the most endearing on earth.Over much the same period, scientific investigations have also changed our view of sloths. No longer are they seen as total misfits in the modern world but, in the words of one specialist sloth investigator, they are 'masters of an alternative lifestyle'.In this wonderfully entertaining celebration of this most unique of creatures, William Hartston reveals the fascinating history of the sloth, from the prehistoric ground sloth to modern pygmy sloths in Panama, explores the current state of the science of sloths and reveals the truth behind sloth behaviour.

    This title is suitable for students preparing for careers in medicine, dentistry, nursing, and allied health, as well as research, teaching, and industry.

    Finally, she traces the last 30 years of Potter's life, when she abandoned books to become a working farmer and pioneer of the conservation movement in the early days of the National Trust. Special features throughout the book will show how Beatrix Potter developed many of her most famous characters, including Peter Rabbit, Mrs. Tiggy-winkle, and Jemima Puddleduck.

    And that's no fun! Enter the Cat in the Hat. His friend Gecko is an expert at hiding. Maybe Gecko can share some tips with the kids? So off they go to the jungle, where Gecko teaches them how to hide in plain sight--using camouflage! Kids won't be able to hide their delight in this rhymed Step 2, Step into Reading book based on an episode from the new PBS Kids television show The Cat in the Hat Knows a Lot About That! (Step 2 is for children who recognize familiar words and sound out new words with aural and visual cues. Step 2 titles have simple stories, basic vocabulary, and short sentences.)

    A Sunday Telegraph top 15 Christmas gift book of 2019 A dog is for life, but an old dog's wisdom is for ever. 'A truly heartwarming book - a perfect gift for any dog lover' Trisha Ashley'The Wisdom of Old Dogs is an absolute must-have' Countryside Magazine'A beautiful read that will leave dog owners and animal lovers brimming over with love and gratitude' Woman's Way Magazine Full of practical advice, uplifting stories, and scientific expertise, this book reveals how dogs can be a constant source of wisdom, comfort and love in their old age.The perfect Christmas present for anyone who treasures these wonderful animals.

    Our genetic makeup determines so much about who we are, and what we pass on to our children—from eye color, to height, to health, and even our longevity. Genetics 101 breaks down the science of how genes are inherited and passed from parents to offspring, what DNA is and how it works, how your DNA affects your health, and how you can use your personal genomics to find out more about who you are and where you come from. Whether you’re looking for a better scientific understanding of genetics, or looking into your own DNA, Genetics 101 is your go-to source to discover more about both yourself and your ancestry.

    Whenyou upgrade to Extra Class, you gain access to the entire Amateur Radio frequency spectrum. Ues this book to ace the top-level ham radio licensing exam. Our expert instruction will lead you through all of the knowledge you need to pass the exam: rules, specific operating skills and more advanced electronics theory.

    It is written to impart a sense of intellectual history of biochemistry, an understanding of the tools and approaches used to solve biochemical puzzles, and a hint of the excitement that accompanies new discoveries. This edition has been thoroughly updated to reflect the most recent advances in biochemistry, particularly in the areas of genomics and structural biology. A new chapter focuses on cytoskeletal and motor proteins, currently one of the most active areas of research in biochemistry.

    With a look at diet in relation to nutrition, this Very Short Introduction provides an overview of the biochemistry of nutrition and the health risks associated with poor nutrition- including obesity and types of food allergies. It provides an essential guide to effectively understand the principles of, and necessary reasons for, a healthy diet.ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

    Primates and cetaceans, at first they appear very different. Yet both are large brained, intelligent mammals who exhibit complex communication and social patterns. This book studies these animals side by side and comes up with some perhaps surprising results, which teach us about another large brained mammal, man.

    Colorful sidebars and numerous photographs highlight key information and provide extra training tips that every owner will appreciate.