But things changed dramatically when he began suffering from inexplicable fatigue. In a matter of weeks, his organs were failing and he was read his last rites. Doctors were baffled by his condition, which they had yet to even diagnose. Floating in and out of consciousness, Fajgenbaum prayed for a second chance, the equivalent of a dramatic play to second the game into overtime.Miraculously, Fajgenbaum survived--only to endure repeated near-death relapses from what would eventually be identified as a form of Castleman disease, an extremely deadly and rare condition that acts like a cross between cancer and an autoimmune disorder. When he relapsed while on the only drug in development and realized that the medical community was unlikely to make progress in time to save his life, Fajgenbaum turned his desperate hope for a cure into concrete action: Between hospitalizations he studied his own charts and tested his own blood samples, looking for clues that could unlock a new treatment. With the help of family, friends, and mentors, he also reached out to other Castleman disease patients and physicians, and eventually came up with an ambitious plan to crowdsource the most promising research questions and recruit world-class researchers to tackle them. Instead of waiting for the scientific stars to align, he would attempt to align them himself.More than five years later and now married to his college sweetheart, Fajgenbaum has seen his hard work pay off: A treatment he identified has induced a tentative remission and his novel approach to collaborative scientific inquiry has become a blueprint for advancing rare disease research. His incredible story demonstrates the potency of hope, and what can happen when the forces of determination, love, family, faith, and serendipity collide.

    Frank, informative, and written with Larry Gonick's characteristic comic verve and scientific accuracy, this book gives a comprehensive discussion of the spectrum of human sexuality, including sexual structures and functions, gender roles and sexual identity, sexual arousal and response, sexual communication, love, marriage and other arrangements, contraception, and sexual health -- without the fig leaves.

    That much is true—but the epidemic is NOT obesity. The real crisis lies in the toxic stigma placed on certain bodies and the impact of living with inequality—not the numbers on a scale. In a mad dash to shrink our bodies, many of us get so caught up in searching for the perfect diet, exercise program, or surgical technique that we lose sight of our original goal: improved health and well-being. Popular methods for weight loss don’t get us there and lead many people to feel like failures when they can’t match unattainable body standards. It’s time for a cease-fire in the war against obesity.Dr. Linda Bacon and Dr. Lucy Aphramor’s Body Respect debunks common myths about weight, including the misconceptions that BMI can accurately measure health, that fatness necessarily leads to disease, and that dieting will improve health. They also help make sense of how poverty and oppression—such as racism, homophobia, and classism—affect life opportunity, self-worth, and even influence metabolism.Body insecurity is rampant, and it doesn’t have to be. It’s time to overcome our culture’s shame and distress about weight, to get real about inequalities and health, and to show every body respect.

    Among the most compelling and perplexing of these symptoms are the strange visual hallucinations and distortions of space, time, and body image which migraineurs sometimes experience. Portrayals of these uncanny states have found their way into many works of art, from the heavenly visions of Hildegard von Bingen to Alice in Wonderland. Dr. Oliver Sacks argues that migraine cannot be understood simply as an illness, but must be viewed as a complex condition with a unique role to play in each individual's life.

    Though the world at first recoiled at the notion of a woman studying medicine, her intelligence and intensity ultimately won her the acceptance of the male medical establishment. In 1849, she became the first woman in America to receive an M.D. She was soon joined in her iconic achievement by her younger sister, Emily, who was actually the more brilliant physician.Exploring the sisters’ allies, enemies, and enduring partnership, Janice P. Nimura presents a story of trial and triumph. Together, the Blackwells founded the New York Infirmary for Indigent Women and Children, the first hospital staffed entirely by women. Both sisters were tenacious and visionary, but their convictions did not always align with the emergence of women’s rights—or with each other. From Bristol, Paris, and Edinburgh to the rising cities of antebellum America, this richly researched new biography celebrates two complicated pioneers who exploded the limits of possibility for women in medicine. As Elizabeth herself predicted, "a hundred years hence, women will not be what they are now."

    Authors Barbara Ehrenreich and Deirdre English have never lost faith in science itself, but insist that we hold those who interpret it to higher standards. Women are entering the medical and scientific professions in greater numbers but as recent research shows, experts continue to use pseudoscience to tell women how to live. This edition of For Her Own Good provides today's readers with an indispensable dose of informed skepticism.

     Heather Sellers is face-blind-that is, she has prosopagnosia, a rare neurological condition that prevents her from reliably recognizing people's faces. Growing up, unaware of the reason for her perpetual confusion and anxiety, she took what cues she could from speech, hairstyle, and gait. But she sometimes kissed a stranger, thinking he was her boyfriend, or failed to recognize even her own father and mother. She feared she must be crazy. Yet it was her mother who nailed windows shut and covered them with blankets, made her daughter walk on her knees to spare the carpeting, had her practice secret words to use in the likely event of abduction. Her father went on weeklong "fishing trips" (aka benders), took in drifters, wore panty hose and bras under his regular clothes. Heather clung to a barely coherent story of a "normal" childhood in order to survive the one she had. That fairy tale unraveled two decades later when Heather took the man she would marry home to meet her parents and began to discover the truth about her family and about herself. As she came at last to trust her own perceptions, she learned the gift of perspective: that embracing the past as it is allows us to let it go. And she illuminated a deeper truth-that even in the most flawed circumstances, love may be seen and felt. Watch a Video

    In fact, your body is actually endowed with many self-defense measures to hold on to fat. For example, fat can use stem cells to regenerate; increase our appetite if it feels threatened; and use bacteria, genetics, and viruses to expand itself. The secret to losing twenty pounds? You have to work with your fat, not against it. Tara explains how your fat influences your appetite and willpower, how it defends itself when attacked, and why it grows back so quickly. The Secret Life of Fat brings cutting-edge research together with historical perspectives to reveal fat’s true identity: an endocrine organ that, in the right amount, is critical to our health. Fat triggers puberty, enables our reproductive and immune systems, and even affects brain size.Although we spend $60 billion annually fighting fat, our efforts are often misinformed and misdirected. Tara expertly illustrates the complex role that genetics, hormones, diet, exercise, and history play in our weight, and The Secret Life of Fat sets you on the path to beat the bulge once and for all.

    Drawing from scientific research, in-depth interviews with experts and other introverts, and her personal story, Granneman reveals the clockwork behind the introvert’s mind—and why so many people get it wrong initially.Whether you are a bona fide introvert, an extrovert anxious to learn how we tick, or a curious ambivert, these revelations will answer the questions you’ve always had:• What’s going on when introverts go quiet?• What do introvert lovers need to flourish in a relationship?• How can introverts find their own brand of fulfillment in the workplace?• Do introverts really have a lot to say—and how do we draw it out?• How can introverts mine their rich inner worlds of creativity and insight?• Why might introverts party on a Friday night but stay home alone all Saturday?• How can introverts speak out to defend their needs?With other myths debunked and truths revealed, The Secret Lives of Introverts is an empowering manifesto that guides you toward owning your introversion by working with your nature, rather than against it, in a world where you deserve to be heard.

    To get the USDA-recommended daily quota of vitamin D, for example, you need to eat 15 eggs or 26 sardines; of iron, 414 almonds or 15 cups of broccoli. So we rely on nutritional supplements—vitamins and minerals, probiotics and enzymes—but the variety of pills, products, and elixirs on the market today is overwhelming. And, as we have seen in recent news, some of these products are downright fakes. Trusted natural health physician and bestselling author Tieraona Low Dog, M.D. provides a personalized approach to using nutritional supplements for your specific health needs, helping you navigate the complex and often confusing landscape of vitamins, minerals, and more.   Dr. Low Dog explains the basics about every essential nutritional supplement and guides the reader in creating a personalized supplement plan, tailored to individual genetics, age, gender, and lifestyle. Low Dog evaluates current research, explains the relationship between food and supplements, describes how medications cause chemical imbalances in the body, and advises on how to judge brands and read labels.   Low Dog engages and encourages readers to take charge of their own health and provides guidance to find the right combination of nutritional supplements to improve mood, strength, energy, and well-being.

    Bringing an Asian American perspective to this almostimplausible story, Huang depicts the twins, arriving in Bostonin 1829, first as museum exhibits but later as financially savvyshowmen who gained their freedom and traveled the backroadsof rural America to bring “entertainment” to the Jacksonianmobs. Their rise from subhuman, freak-show celebrities to richsouthern gentry; their marriage to two white sisters, resulting intwenty-one children; and their owning of slaves, is here not justanother sensational biography but a Hawthorne-like excavationof America’s historical penchant for finding feast in the abnormal,for tyrannizing the “other”—a tradition that, as Huangreveals, becomes inseparable from American history itself.