Translated into eight languages, it is an essential textbook, an accessible reference, and a bestselling text worldwide.This authoritative textbook retains the successful layout and approach of the bestselling fourth edition Four extra chapters have been added on dry eye, scleritis, corneal and refractive surgery, and systemic diseases.Each chapter have been updated and expanded and the number of illustrations greatly increased.Over a third of the illustrations are new for this editionFour extra chapters have been added on dry eye, scleritis, corneal and refractive surgery, and systemic diseases.The contents of each chapter have been updated and expanded and the number of illustrations has significantly increased.

    Frizzle were a physics student of Stephen Hawking, she might have written THE UNIVERSE IN YOUR HAND, a wild tour through the reaches of time and space, from the interior of a proton to the Big Bang to the rough suburbs of a black hole. It's friendly, excitable, erudite, and cosmic."—Jordan Ellenberg, New York Times besteselling author of How Not To Be WrongQuantum physics, black holes, string theory, the Big Bang, dark matter, dark energy, parallel universes: even if we are interested in these fundamental concepts of our world, their language is the language of math. Which means that despite our best intentions of finally grasping, say, Einstein's Theory of General Relativity, most of us are quickly brought up short by a snarl of nasty equations or an incomprehensible graph.Christophe Galfard's mission in life is to spread modern scientific ideas to the general public in entertaining ways. Using his considerable skills as a brilliant theoretical physicist and successful young adult author, The Universe in Your Hand employs the immediacy of simple, direct language to show us, not explain to us, the theories that underpin everything we know about our universe. To understand what happens to a dying star, we are asked to picture ourselves floating in space in front of it. To get acquainted with the quantum world, we are shrunk to the size of an atom and then taken on a journey. Employing everyday similes and metaphors, addressing the reader directly, and writing stories rather than equations renders these astoundingly complex ideas in an immediate and visceral way.Utterly captivating and entirely unique, The Universe in Your Hand will find its place among other classics in the field.

    And no delay causes more parental anxiety than late talking, which is associated in many parents' minds with such serious conditions as autism and severe intellectual disability. In fact, as children's speech expert Stephen Camarata points out in this enlightening book, children are late in beginning to talk for a wide variety of reasons. For some children, late talking may be a symptom of other, more serious, problems; for many others, however, it may simply be a stage with no long-term complications.Camarata describes in accessible language what science knows about the characteristics and causes of late talking. He explains that late talking is only one of a constellation of autism symptoms. Although all autistic children are late talkers, not all late-talking children are autistic.Camarata draws on more than twenty-five years of professional experience diagnosing and treating late talkers--and on his personal experience of being a late talker himself and having a late-talking son. He provides information that will help parents navigate the maze of doctors, speech therapists, early childhood services, and special education; and he describes the effect that late talking may have on children's post-talking learning styles.

    - Book Review Editor of the journal "Modern Pathology," the official journal of the United States-Canadian Academy of Pathology and prestigious best-selling author. This is the 5th edition of a book that has already established itself as the classic pathology textbook in India. This new edition has been updated, and improved to meet the highest standards of quality and information now required by pathology courses around the world. Editorially this new edition carries particular emphasis on molecular pathology and genetics in the pathogenesis of various diseases, and the pathological discussions of each organ or system is preceded with a short description of its structure and function. The material is integrated with extensive page cross references between chapters and the whole book has been thoroughly re-edited, with new images, illustrations and line drawings. The book is accompanied by the free student revision aid "Pathology - Quick Review and MCQs" and therefore, together as a package, "Textbook of Pathology, 5E" will be a major contribution to the required reading of undergraduate medical students worldwide.

    A practical, science-based guide that shows how in just 10 to 15 minutes a day you can make mediation part of your routine and improve your happiness, wellbeing and productivity, for people of all ages and all walks of life.Can't sleep because your thoughts won't switch off? Does a constant stream of unnecessary chatter run thought your head? Mediation is a simple practice that can help you address these common experiences.Through scientifically based research SILENCE YOUR MIND shows how meditation can fit into your busy schedule to improve your sense of wellbeing, help you reach your potential in sport, work and creative pursuits, and increase the quality of your life.For just 10 minutes a day you can feel the benefits that meditation brings to your mental and physical health.Australia's world-leading expert on meditation, Dr Ramesh Manocha, writes in a clear, straight forward way that will appeal to people who wouldn't normally consider meditation, as well as those who want to make it part of their daily lives.

    Some didn’t make it out alive. After hearing whispers that seemed almost too awful to believe, BuzzFeed News investigative reporter Christine Kenneally embarked on a years-long journey to find out what really went on in these institutions. What she discovered was even more horrifying than the legend: the systematic abuse and even the alleged murder of children by nuns. Her searing report, which is part investigation, part true crime drama, part ghost story, cracks open a secret history of American life — and adds a vast new dimension to the Catholic church’s mistreatment of children. From a world shrouded in secrecy, Kenneally tells the story of St. Joseph’s Orphanage in Burlington, Vermont, and of Sally Dale, the plucky redhead who was the apple of the nuns’ eyes. Until they decided to make an example of her, administering daily torments, isolating her from the rest of the world, and convincing her that she would never escape. Of all the children who passed through St. Joseph’s, she may have been there the longest. The horrors she suffered and the deaths she said she witnessed did not come into full view until the day, decades later, when she attended a St Joseph’s reunion. Then the past came flooding back like a torrent. Along with scores of other survivors, and guided by an idealistic young lawyer, Sally somehow found the courage to come forward and tell the world what she had experienced. She wanted more than anything else to be heard and believed. But she was going up against one of the most powerful institutions in the world, and she was in for the fight of a lifetime. The legal battle that ensued upended every assumption that the people of Burlington had. Could memory be trusted? Could forgetting be forgotten? Could a pleasant community turn a blind eye to evil? And could nuns, the very women charged with protecting these most vulnerable members of society, have instead tortured or even killed them? The Catholic sex abuse scandal – which most recently yielded a grand jury report on how the church hid the crimes of hundreds of priests — shattered the silence that for so long had protected the church. But the truth about what went on inside its orphanages has somehow remained all but unspoken, even as other countries have undertaken huge national inquiries. In the US, there has been no reckoning. The orphanages’ dark secrets, like the dead children who haunt survivors’ dreams, still lay buried. Until now. Through painstaking reporting, based in thousands of pages of documents — many of them secret — and interviews with survivors, Kenneally connects what happened at St. Joseph’s to similar accounts that emerged from seven countries across three continents, revealing a terrible matrix of corroboration.

    Author Suryacitta, aka The Happy Buddha, explores what happiness actually is and how we all can achieve it through the transformational practice of mindfulness meditation. This simple act of meditation is as unintimidating as it is effective. Even those completely new to meditation will feel the effects of mindfulness meditation immediately, and have their inner happiness flourish.

    The Eighth Edition has been thoroughly revised and updated and is available in both print and e-book formats.Janeway s Immunobiology continues to set the standard for currency and authority with its clear writing style and organization, uniform art program, and scientific accuracy. It presents a consistent point of view throughout that of the host s interaction with an environment containing many species of potentially harmful microorganisms. The full-color art program is conceptually coherent and illustrates the processes and mechanisms underlying the concepts in the text. The 16 chapters in this readable, accessible textbook are organized and presented in such a way as to help deliver a complete one-semester immunology course, beginning with innate immunity, then moving to adaptive immunity, and ending with applied clinical immunology.Discussion questions are provided at the end of Chapters 2 to 16. These questions can be used for review, or as the basis for discussion in class or in informal study groups. Summaries conclude each section and each chapter. As in previous editions, a caduceus icon in the margins indicates topics which are correlated to Case Studies in Immunology, Sixth Edition by Geha and Notarangelo.New in the Eighth EditionInnate immunity has been updated and expanded and is now presented in two separate chapters (Chapters 2 and 3), as well as being further emphasized in the rest of the textbook. Chapter 2 covers antimicrobial peptides and the complement system, and Chapter 3 deals with cellular innate receptors and cell-mediated innate immunity (e.g. TLRs, phagocytosis, NK cells, interferon production, innate-like lymphocytes). The section on complement has been reworked and reconceived explaining the lectin pathway first making it easier to teach by placing it into the context of innate recognition. Evolution is now incorporated throughout the text, helping students see similar strategies used by different organisms. The text and figures of Chapter 7 Signaling Through Immune System Receptors have been revised to present a cohesive synthesis of signaling for immunology, focusing on improved illustration of antigen recognition signaling and lymphocyte activation. Signaling through other receptors is dealt with wherever appropriate throughout the book. Updated chapter on B-cell immune responses (Chapter 10), especially on trafficking of B cells in peripheral lymphoid organs (e.g. lymph nodes) and the locations at which they encounter antigen. Coverage of mucosal immunity (Chapter 12) has been brought up to date, including responses to the commensal microbiota and the role of specialized dendritic cells and the regulatory T cells in maintaining tolerance to food antigens and commensal bacteria. Chapter 13, Failures of Host Defense Mechanisms, has been reorganized and revised to structure an understanding of primary immunodeficiencies in the context of developmental pathways. Chapter 16, Manipulation of the Immune Response, has been heavily revised to include a greater emphasis on clinical issues and a complete update of immunotherapeutics and vaccines. Many new and revised figures illustrate the processes and mechanisms underlying the concepts presented in the text. The icons used have been updated and expanded to incorporate a new emphasis on signaling pathways. New references have been added throughout the text.

    Now in full color for easier referencing, this New Edition continues the tradition, incorporating a wealth of exciting updates and changes-ensuring you have access to today's authoritative knowledge to best diagnose and treat every pediatric patient you see. Whether you're treating patients in the office or in the hospital, or preparing for the boards, Nelson Textbook of Pediatrics, 18th Edition is your comprehensive guide to providing the best possible care.Get an enhanced focus on general pediatrics with editorial contributions from new editor Dr. Bonita F. Stanton.Treat your inpatient and ambulatory patients more effectively with the absolute latest on new topics such as quality improvement and patient care safety . school violence and bullying . preventive measures . vitamin deficiencies . adolescent rape . effect of war on children . and more.Improve your therapeutic skills with the newest knowledge on the principles of antibiotic therapy . antiviral therapy . antiparasitic therapy . antimycobacterial therapy . and others.Understand the principles of therapy and which drugs and dosages to prescribe for every disease.Locate key content more easily and identify clinical conditions quicker thanks to a new full-color design and full-color photographs.Get an enhanced focus on general pediatrics with editorial contributions from new editor Dr. Bonita F. Stanton.Treat your inpatient and ambulatory patients more effectively with the absolute latest on new topics such as quality improvement and patient care safety *school violence and bullying * preventive measures * vitamin deficiencies * adolescent rape * effect of war on children * and more.Improve your therapeutic skills with the newest knowledge on the principles of antibiotic therapy * antiviral therapy * antiparasitic therapy * antimycobacterial therapy * and others.Understand the principles of therapy and which drugs and dosages to prescribe for every disease.Locate key content more easily and identify clinical conditions quicker thanks to a new full-color design and full-color photographs.

    Conventional wisdom calls it incurable, but renowned Dr. Gabriel Cousens counters that claim with this breakthrough book. There Is a Cure for Diabetes lays out a three-week plan for reversing the negative genetic expression of diabetes to a physiology of health and well-being. Dr. Cousens’s method, widely tested at his famous Tree of Life centers, is to reset the DNA through green juice fasting and a 100% organic, nutrient-dense, vegan, low-glycemic, low-insulin-scoring, and high-mineral diet of living foods in the first twenty-one days. Both practical and inspirational, the book explains how to abandon the widespread “culture of death”–symbolized by addictive junk food–that fosters diabetes in favor of a more natural, nurturing approach. The program renders insulin and related medicines unnecessary within four days as the blood sugar drops to normal levels; and the diabetic shifts into a non-diabetic physiology within two weeks. The third week focuses on live-food preparation, featuring 100 delicious raw recipes. Dr. Cousens emphasizes regular consultations, monitoring blood chemistries, and emotional support, and includes a one-year support program to help maintain a diabetes-free life.

    As corporations seek to save money and government agencies aim to increase constituent access, minimum qualifications for the guardians of our nation’s healthcare continue to decline—with deadly consequences. This is a story that has not yet been told, and one that has dangerous repercussions for all Americans.

    A neurologist's insightful and compassionate look into the misunderstood world of psychosomatic disorders, told through individual case histories

    “I walk with a new spring in my step and I look at life through physics-colored eyes,” wrote one such fan. When Lewin’s lectures were made available online, he became an instant YouTube celebrity, and The New York Times declared, “Walter Lewin delivers his lectures with the panache of Julia Child bringing French cooking to amateurs and the zany theatricality of YouTube’s greatest hits.” For more than thirty years as a beloved professor at the Massachusetts Institute of Technology, Lewin honed his singular craft of making physics not only accessible but truly fun, whether putting his head in the path of a wrecking ball, supercharging himself with three hundred thousand volts of electricity, or demonstrating why the sky is blue and why clouds are white. Now, as Carl Sagan did for astronomy and Brian Green did for cosmology, Lewin takes readers on a marvelous journey in For the Love of Physics, opening our eyes as never before to the amazing beauty and power with which physics can reveal the hidden workings of the world all around us. “I introduce people to their own world,” writes Lewin, “the world they live in and are familiar with but don’t approach like a physicist—yet.” Could it be true that we are shorter standing up than lying down? Why can we snorkel no deeper than about one foot below the surface? Why are the colors of a rainbow always in the same order, and would it be possible to put our hand out and touch one? Whether introducing why the air smells so fresh after a lightning storm, why we briefly lose (and gain) weight when we ride in an elevator, or what the big bang would have sounded like had anyone existed to hear it, Lewin never ceases to surprise and delight with the extraordinary ability of physics to answer even the most elusive questions. Recounting his own exciting discoveries as a pioneer in the field of X-ray astronomy—arriving at MIT right at the start of an astonishing revolution in astronomy—he also brings to life the power of physics to reach into the vastness of space and unveil exotic uncharted territories, from the marvels of a supernova explosion in the Large Magellanic Cloud to the unseeable depths of black holes. “For me,” Lewin writes, “physics is a way of seeing—the spectacular and the mundane, the immense and the minute—as a beautiful, thrillingly interwoven whole.” His wonderfully inventive and vivid ways of introducing us to the revelations of physics impart to us a new appreciation of the remarkable beauty and intricate harmonies of the forces that govern our lives.

    The DOs chronicles the development of this controversial medical movement from the nineteenth century to the present. Historian Norman Gevitz describes the philosophy and practice of osteopathy, as well as its impact on medical care. From the theories underlying the use of spinal manipulation developed by osteopathy's founder, Andrew Taylor Still, Gevitz traces the movement's early success, despite attacks from the orthodox medical community, and details the internal struggles to broaden osteopathy's scope to include the full range of pharmaceuticals and surgery. He also recounts the efforts of osteopathic colleges to achieve parity with institutions granting M.D. degrees and looks at the continuing effort by osteopathic physicians and surgeons to achieve greater recognition and visibility.In print continuously since 1982, The DOs has now been thoroughly updated and expanded to include two new chapters addressing recent and current challenges and to bring the history of the profession up to the beginning of the new millennium.

    This entertaining reference reviews fundamental cardiac anatomy and physiology, explains how to obtain and interpret a rhythm strip, and teaches the reader how to recognize and treat 18 arrhythmias. It also explains how to obtain and interpret 12-lead ECGs, posterior ECGs, and 15- and 18-lead ECGs. The familiar Incredibly Easy! elements found throughout the reference make it easy to remember key points.