Focusing on four specific examples — corn, silkworms, domestic cats, and apples — she traces the histories of species that have been fundamentally altered over the centuries by the whims and needs of people.

    In the mid-1970s, scientists began using DNA sequences to reexamine the history of all life. Perhaps the most startling discovery to come out of this new field—the study of life’s diversity and relatedness at the molecular level—is horizontal gene transfer (HGT), or the movement of genes across species lines. It turns out that HGT has been widespread and important. For instance, we now know that roughly eight percent of the human genome arrived not through traditional inheritance from directly ancestral forms, but sideways by viral infection—a type of HGT.David Quammen chronicles these discoveries through the lives of the researchers who made them—such as Carl Woese, the most important little-known biologist of the twentieth century; Lynn Margulis, the notorious maverick whose wild ideas about “mosaic” creatures proved to be true; and Tsutomu Wantanabe, who discovered that the scourge of antibiotic-resistant bacteria is a direct result of horizontal gene transfer, bringing the deep study of genome histories to bear on a global crisis in public health.

    She conjures up early operating theaters--no place for the squeamish--and surgeons, working before anesthesia, who were lauded for their speed and brute strength. These medical pioneers knew that the aftermath of surgery was often more dangerous than their patients' afflictions, and they were baffled by the persistent infections that kept mortality rates stubbornly high. At a time when surgery couldn't have been more hazardous, an unlikely figure stepped forward: a young, melancholy Quaker surgeon named Joseph Lister, who would solve the deadly riddle and change the course of history.Fitzharris dramatically recounts Lister's discoveries in gripping detail, culminating in his audacious claim that germs were the source of all infection--and could be countered by antiseptics. Focusing on the tumultuous period from 1850 to 1875, she introduces us to Lister and his contemporaries--some of them brilliant, some outright criminal--and takes us through the grimy medical schools and dreary hospitals where they learned their art, the deadhouses where they studied anatomy, and the graveyards they occasionally ransacked for cadavers.Eerie and illuminating, The Butchering Art celebrates the triumph of a visionary surgeon whose quest to unite science and medicine delivered us into the modern world.

    He was one of the leading pioneers of the greatest revolution in twentieth-century science: quantum mechanics. The youngest theoretician ever to win the Nobel Prize for Physics, he was also pathologically reticent, strangely literal-minded and legendarily unable to communicate or empathize. Through his greatest period of productivity, his postcards home contained only remarks about the weather.Based on a previously undiscovered archive of family papers, Graham Farmelo celebrates Dirac's massive scientific achievement while drawing a compassionate portrait of his life and work. Farmelo shows a man who, while hopelessly socially inept, could manage to love and sustain close friendship.The Strangest Man is an extraordinary and moving human story, as well as a study of one of the most exciting times in scientific history.'A wonderful book . . . Moving, sometimes comic, sometimes infinitely sad, and goes to the roots of what we mean by truth in science.' Lord Waldegrave, Daily Telegraph

    In this book, he expands the points he has made, and claims that this debate is not so much about religion versus science, as about the nature of science itself. With infectious enthusiasm, he reveals the mechanics of evolutionary theory, explains how it is rooted in the testable and verifiable scientific method, and why it is therefore a sound explanation of our beginning. He argues passionately that to continue to assert otherwise, to continue to insist that creationism has a place in the science classroom is harmful not only to our children, but to the future of the greater world as well.

    Unlike Origin, this book focuses on human ancestry and offers a concise, nontechnical survey of the state of mid-nineteenth-century knowledge about primate and human paleontology and ethology.Man's Place in Nature concurs with Darwin's assertion of the absence of a physiologic and psychic structural line of demarcation between humans and apes. Huxley ventures further than Darwin, however, by making the first attempt to apply the principles of evolution directly to the human race (an issue that Darwin skirted). Despite Huxley's acknowledgements of the wide gulf represented by the human capacity for rational speech and language, some Victorian readers were scandalized by the application of Darwinian theory to humans and by Huxley's evidence of the fundamental similarities between the human brain and the ape brain.A landmark of scientific progress, this immensely readable book reflects the stylistic gifts that made its author a popular public speaker.

    But there remains a critical gap in our knowledge: we still know very little about what happened in the first seconds after the Big Bang. At the Edge of Time focuses on what we have recently learned and are still striving to understand about this most essential and mysterious period of time at the beginning of cosmic history.Delving into the remarkable science of cosmology, Dan Hooper describes many of the extraordinary and perplexing questions that scientists are asking about the origin and nature of our world. Hooper examines how we are using the Large Hadron Collider and other experiments to re-create the conditions of the Big Bang and test promising theories for how and why our universe came to contain so much matter and so little antimatter. We may be poised to finally discover how dark matter was formed during our universe's first moments, and, with new telescopes, we are also lifting the veil on the era of cosmic inflation, which led to the creation of our world as we know it.Wrestling with the mysteries surrounding the initial moments that followed the Big Bang, At the Edge of Time presents an accessible investigation of our universe and its origin.

    Isolated and desolate, they were largely overlooked by early explorers until Charles Darwin arrived there in the 1830s. It was Darwin who recognized that Galapagos' isolation and desolation were advantages: the paucity of species and lack of outside influences made the workings of natural selection crystal clear. Since then, every important advance and controversy in evolutionary thinking has had its reflection on the Galapagos. In every sense-intellectually, institutionally, and culturally-the history of science on these islands is a history of the way evolutionary science was done for the past 150 years. Evolution's Workshop tells the story of Darwin's explorations there; the fabulous Gilded Age expeditions, run from rich men's gigantic yachts, that featured rough-and-ready science during the day and black-tie dinners every night; the struggle for control of research on the Galapagos; the current efforts by "creation scientists" to use the Galapagos to undercut evolutionary teaching; and many other compelling stories.

    Pluto is entrenched in our cultural and emotional view of the cosmos, and Neil deGrasse Tyson, award-winning author and director of the Rose Center, is on a quest to discover why. He stood at the heart of the controversy over Pluto's demotion, and consequently Plutophiles have freely shared their opinions with him, including endless hate mail from third-graders. With his inimitable wit, Tyson delivers a minihistory of planets, describes the oversized characters of the people who study them, and recounts how America's favorite planet was ousted from the cosmic hub.

    Yuri Gagarin is one of the great heroes of the twentieth century, but the details of his life and the Russian space effort have been shrouded in secrecy: even the names of the engineers who worked with Gagarin were a mystery to the West for many years.Starman is the first book to tell the compelling story behind Gagarin's life and his audacious first flight into space aboard a converted nuclear weapon.He was once the most famous man in the world yet in his life, as in death, he was a man the world knew almost nothing about.

    Judy Mikovits is a modern-day Rosalind Franklin, a brilliant researcher shaking up the old boys’ club of science with her groundbreaking discoveries. And like many women who have trespassed into the world of men, she uncovered decades-old secrets that many would prefer to stay buried. From her doctoral thesis, which changed the treatment of HIV-AIDS, saving the lives of millions, including basketball great Magic Johnson, to her spectacular discovery of a new family of human retroviruses, and her latest research which points to a new golden age of health, Dr. Mikovits has always been on the leading edge of science. With the brilliant wit one might expect if Erin Brockovich had a doctorate in molecular biology, Dr. Mikovits has seen the best and worst of science. When she was part of the research community that turned HIV-AIDS from a fatal disease into a manageable one, she saw science at its best. But when her investigations questioned whether the use of animal tissue in medical research were unleashing devastating plagues of chronic diseases, such as autism and chronic fatigue syndrome, she saw science at its worst. If her suspicions are correct, we are looking at a complete realignment of scientific practices, including how we study and treat human disease. Recounting her nearly four decades in science, including her collaboration of more than thirty-five years with Dr. Frank Ruscetti, one of the founders of the field of human retrovirology, this is a behind the scenes look at the issues and egos which will determine the future health of humanity.

    With his classic Why We Get Sick, Dr. Randolph Nesse helped to establish the field of evolutionary medicine. Now he returns with a book that transforms our understanding of mental disorders by exploring a fundamentally new question. Instead of asking why certain people suffer from mental illness, Nesse asks why natural selection has left us all with fragile minds.Drawing on revealing stories from his own clinical practice and insights from evolutionary biology, Nesse shows how negative emotions are useful in certain situations, yet can become overwhelming. Anxiety protects us from harm in the face of danger, but false alarms are inevitable. Low moods prevent us from wasting effort in pursuit of unreachable goals, but they often escalate into pathological depression. Other mental disorders, such as addiction and anorexia, result from the mismatch between modern environment and our ancient human past. And there are good evolutionary reasons for sexual disorders and for why genes for schizophrenia persist. Taken together, these and many more insights help to explain the pervasiveness of human suffering, and show us new paths for relieving it by understanding individuals as individuals.

    Starting once again with fossils, he turns his gaze skyward, showing us how the entirety of the universe’s fourteen-billion-year history can be seen in our bodies. As he moves from our very molecular composition (a result of stellar events at the origin of our solar system) through the workings of our eyes, Shubin makes clear how the evolution of the cosmos has profoundly marked our own bodies. Fully illustrated with black and white drawings.

    In this amazingly comprehensible history of the universe, Simon Singh decodes the mystery behind the Big Bang theory, lading us through the development of one of the most extraordinary, important, and awe-inspiring theories in science.

    The more we discover, the more puzzling the universe appears to be. How and why are the laws of nature what they are? A philosopher and a physicist, world-renowned for their radical ideas in their fields, argue for a revolution. To keep cosmology scientific, we must replace the old view in which the universe is governed by immutable laws by a new one in which laws evolve. Then we can hope to explain them. The revolution that Roberto Mangabeira Unger and Lee Smolin propose relies on three central ideas. There is only one universe at a time. Time is real: everything in the structure and regularities of nature changes sooner or later. Mathematics, which has trouble with time, is not the oracle of nature and the prophet of science; it is simply a tool with great power and immense limitations. The argument is readily accessible to non-scientists as well as to the physicists and cosmologists whom it challenges.