Chapters cover cancer, infection, immune disorders, genetics, and disorders of each body system, highlighting pathophysiologic processes, resulting signs and symptoms, diagnostic test findings, and current treatments. Reader-friendly features include illustrations, checklists, and full-color miniguides illustrating the pathophysiology of specific disorders.This edition has new full-color miniguides on cancer pathophysiology and neuropathology. A new Focus on Genetics feature identifies gene-related discoveries and their implications for treatment or diagnosis. Review questions and answers follow current NCLEX-RN® requirements and alternate-format questions are included.

    Despite massive efforts to eradicate the disease, it remains a major public health problem in poorer tropical regions. But malaria has not always been concentrated in tropical areas. How did other regions control malaria and why does the disease still flourish in some parts of the globe?From Russia to Bengal to Palm Beach, Randall Packard’s far-ranging narrative traces the natural and social forces that help malaria spread and make it deadly. He finds that war, land development, crumbling health systems, and globalization—coupled with climate change and changes in the distribution and flow of water—create conditions in which malaria's carrier mosquitoes thrive. The combination of these forces, Packard contends, makes the tropical regions today a perfect home for the disease.Authoritative, fascinating, and eye-opening, this short history of malaria concludes with policy recommendations for improving control strategies and saving lives.

    Poisons permeate our world. They are in the environment, the workplace, the home. They are in food, our favorite whiskey, medicine, well water. They have been used to cure disease as well as to incapacitate and kill. They smooth wrinkles, block pain, stimulate, and enhance athletic ability. In this entertaining and fact-filled book, science writer Peter Macinnis considers poisons in all their aspects. He recounts stories of the celebrated poisoners in history and literature, from Nero to Thomas Wainewright, and from the death of Socrates to Hamlet and Peter Pan. He discusses the sources of various poisons-from cyanide to strychnine, from Botox to ricin and Sarin gas-as well as their detection. Then he analyzes the science of their action in the body and their uses in medicine, cosmetics, war, and terrorism. With wit and precision, he weighs such questions as: Was Lincoln's volatility caused by mercury poisoning? Was Jack the Ripper an arsenic eater? Can wallpaper kill? For anyone who has ever wondered and been afraid to ask, here is a rich miscellany for your secret questions about toxins.

    The book offers insight into 21st century modern healthcare and the state of society. You will laugh, cry, and question your beliefs about the healthcare system and patients. Read this before you go to the doctor next and share this information with your family. Throughout the United States stories like these are unfolding each day as you witness the stress of physician training and the ups and downs of the physician's and patient's lives. Dr. Brandon Green is a pseudonym, or pen name, for author who wishes to remain anonymous. He is an Attending Surgeon at an inner-city Level 1 Trauma Center. The author's goals for writing this book include the following: 1.Create awareness and discussion about today’s healthcare and society. 2.Raise money with 30% of profits from the sale of this book being donated to healthcare non-profit organizations such as the American Cancer Society, the American Heart Association, and any current global medical pandemic funds. 3.Therapy for the author to recount the intern year, which was more stressful and educational than ever imagined. Unexpected emotions occurred and life lessons were taught beyond the surgical training. The short stories are real occurrences that happened to the author and his other two co-interns in one residency year. The author broke ties with the publisher who wanted to adjust the stories to meet societal norms, and now the work is being self published with profits as above going to charity instead of a large publishing company. The names and locations have been changed to provide privacy protection and follow HIPPA guidelines. The author hopes to continue dialogue and discussion on stories from behind the scenes at hospitals, clinics, and in the operating rooms. It's beneficial to communicate with colleagues and other healthcare professionals and staff running into similar circumstances on a day to day basis. Please visit DIARYOFAHO.COM and email your stories to be published on the website and social media.This is a work of sociology, psychology, medicine, surgery, dealing with the public, putting others ins front of yourself, and self-reflective learning. Any story will be accepted and uploaded into the blog and social media. Stories will be screened for HIPPA compliance prior to publishing online. Thank you for taking the time to read and understand what’s happening in modern healthcare training.

    Bell ruling made government sterilization of "undesirable" citizens the law of the land. New York Times bestselling author Adam Cohen tells the story in Imbeciles of one of the darkest moments in the American legal tradition: the Supreme Court's decision to champion eugenic sterilization for the greater good of the country. In 1927, when the nation was caught up in eugenic fervor, the justices allowed Virginia to sterilize Carrie Buck, a perfectly normal young woman, for being an "imbecile." It is a story with many villains, from the superintendent of the Dickensian Virginia Colony for Epileptics and Feebleminded who chose Carrie for sterilization to the former Missouri agriculture professor and Nazi sympathizer who was the nation's leading advocate for eugenic sterilization. But the most troubling actors of all were the eight Supreme Court justices who were in the majority--including William Howard Taft, the former president; Louis Brandeis, the legendary progressive; and Oliver Wendell Holmes, Jr., America's most esteemed justice, who wrote the decision urging the nation to embark on a program of mass eugenic sterilization

    This is the story of a fateful year that prefigured the events of 1776.In The Fever of 1721, Stephen Coss brings to life an amazing cast of characters in a year that changed the course of medical history, American journalism, and colonial revolution, including Cotton Mather, the great Puritan preacher, son of the president of Harvard College; Zabdiel Boylston, a doctor whose name is on one of Boston's grand avenues; James and his younger brother Benjamin Franklin; and Elisha Cooke and his protegee; Samuel Adams.During the worst smallpox epidemic in Boston history Mather convinced Doctor Boylston to try a procedure that he believed would prevent death--by making an incision in the arm of a healthy person and implanting it with smallpox. Inoculation led to vaccination, one of the most profound medical discoveries in history. Public outrage forced Boylston into hiding, and Mather's house was firebombed.A political fever also raged. Elisha Cooke was challenging the Crown for control of the colony and finally forced Royal Governor Samuel Shute to flee Massachusetts. Samuel Adams and the Patriots would build on this to resist the British in the run-up to the American Revolution. And a bold young printer James Franklin (who was on the wrong side of the controversy on inoculation), launched America's first independent newspaper and landed in jail. His teenage brother and apprentice, Benjamin Franklin, however, learned his trade in James' shop and became a father of the Independence movement.One by one, the atmosphere in Boston in 1721 simmered and ultimately boiled over, leading to the full drama of the American Revolution.

    The most up-to-date and beautifully illustrated text on the market, it has a strong molecular and cellular approach, firmly relating the molecular and cellular biological underpinnings of physiology to the study of human physiology and disease. Contributions from leading physiologists ensure authoritative, cutting-edge information, and thorough and consistent editing have produced a readable and student-friendly text.The smart way to study!Elsevier titles with STUDENT CONSULT will help you master difficult concepts and study more efficiently in print and online! Perform rapid searches. Integrate bonus content from other disciplines. Download text to your handheld device. And a lot more. Each STUDENT CONSULT title comes with full text online, a unique image library, case studies, USMLE style questions, and online note-taking to enhance your learning experience.

    Stewart's history of the Donner Party is “compulsive reading ??—?? a wonderful account, both scholarly and gripping, of horrifying episode in the history of the west" (Pulitzer Prize-winner Arthur Schlesinger, Jr.)The tragedy of the Donner party constitutes one of the most amazing stories of the American West. In 1846 eighty-seven people ??—?? men, women, and children ??—?? set out for California, persuaded to attempt a new overland route. After struggling across the desert, losing many oxen, and nearly dying of thirst, they reached the very summit of the Sierras, only to be trapped by blinding snow and bitter storms. Many perished; some survived by resorting to cannibalism; all were subjected to unbearable suffering. Incorporating the diaries of the survivors and other contemporary documents, George R. Stewart wrote the definitive history of that ill-fated band of pioneers. Ordeal by Hunger: The Story of the Donner Party is an astonishing account of what human beings may endure and achieve in the final press of circumstance.

    From the conquest of Mexico by smallpox as much as by the Spanish, to the bubonic plague in China, to the typhoid epidemic in Europe, the history of disease is the history of humankind. With the identification of AIDS in the early 1980s, another chapter has been added to this chronicle of events, which William McNeill explores in his new introduction to this updated editon.Thought-provoking, well-researched, and compulsively readable, Plagues and Peoples is that rare book that is as fascinating as it is scholarly, as intriguing as it is enlightening. "A brilliantly conceptualized and challenging achievement" (Kirkus Reviews), it is essential reading, offering a new perspective on human history.

    Squirming parasites, bursting pustules, rotting limbs, and cascading diarrhea: it's all depicted here in vivid detail. Sometimes the remedy proved as unbearable as the sickness itself. Whether performing dire dentistry or ice-pick lobotomies, bloodletting or blistering, the medical practitioners of history were ever inventive, if not effective. Disease played a role in shaping human history, too: read how measles and smallpox hastened the decline of the native peoples of the Americas, and how typhus helped to defeat Napoleon. Extraordinary anecdotes abound, such as the cautionary tale of Typhoid Mary and how a cow called Blossom saved the day. Packed with startling medical illustrations, this morbidly fascinating study of all that ails is bound to grip you from page one and leave you reaching for the disinfectant."

    In Sam Houston, James L. Haley explores Houston’s momentous career and the complex man behind it. Haley’s fifteen years of research and writing have produced possibly the most complete, most personal, and most readable Sam Houston biography ever written. Drawn from personal papers never before available as well as the papers of others in Houston’s circle, this biography will delight anyone intrigued by Sam Houston, Texas history, Civil War history, or America’s tradition of rugged individualism.Sam Houston is the winner of numerous awards, including:T. R. Fehrenbach Book Award, Texas Historical CommissionCoral Horton Tullis Memorial Prize, Texas State Historical AssociationSpur Award, Biography, Western Writers of America

    It is hard to find a photo of Humphrey Bogart or Lauren Bacall without a cigarette. No product has been so heavily promoted or has become so deeply entrenched in American consciousness.And no product has received such sustained scientific scrutiny. The development of new medical knowledge demonstrating the dire harms of smoking ultimately shaped the evolution of evidence-based medicine. In response, the tobacco industry engineered a campaign of scientific disinformation seeking to delay, disrupt, and suppress these studies. Using a massive archive of previously secret documents, historian Allan Brandt shows how the industry pioneered these campaigns, particularly using special interest lobbying and largesse to elude regulation.But even as the cultural dominance of the cigarette has waned and consumption has fallen dramatically in the U.S., Big Tobacco remains securely positioned to expand into new global markets. The implications for the future are vast: 100 million people died of smoking-related diseases in the 20th century; in the next 100 years, we expect 1 billion deaths worldwide.

    . . . Almost every page could make you say, I didn’t know that!"Tampa Tribune"Gannon’s love for Florida comes through in a marvelous narrative style [that] doesn’t bog down in dates and reams of facts that historians find interesting, but others don’t."--Miami Herald"First rate . . . desperately needed . . . entertaining . . . fun!"--Orlando Sentinel"Gannon is a lifelong student of the history of his state, an acclaimed teacher, a masterful and tireless raconteur, and a superb stylist. Florida: A Short History showcases each of these strengths and talents and contains the latest archaeological and historical scholarship."--Florida Historical QuarterlyAs if Ponce de León, who happened on the peninsula in 1513, returned today to demand a quick reckoning (“Tell me what happened after I was there, but leave out the boring parts!”), Michael Gannon recounts the longest recorded history of any state in the nation in twenty-seven brisk, fully illustrated chapters.From indigenous tribes who lived along spring-fed streams to environmentalists who labor to "Save Our Rivers," from the first conquistadors whose broad black ships astonished the natives to the 123,000 refugees whose unexpected immigration stunned South Floridians in 1980, the story of the state is as rich and distinctive as the story of America.And it’s older than most people think. As Gannon writes, “By the time the Pilgrims came ashore at Plymouth, St. Augustine was up for urban renewal. It was a town with fort, church, seminary, six-bed hospital, fish market, and about 120 shops and houses. Because La Florida stretched north from the Keys to Newfoundland and west to Texas, St. Augustine could claim to be the capital of much of what is now the United States.”Gannon tells his fast-marching saga in chronological fashion. Starting with the wilderness of the ancient earth, he fills the landscape with Indians, colonists, pioneers, entrepreneurs, politicians, and the panorama of Florida today--“the broad superhighways that wind past horse farms, retirement communities, international airports, launch pads, futuristic attractions, and come to rest, finally, amidst the gleaming towers of Oz?like cities.” This revised edition concludes with a look into the twenty-first century, including “in-migration,” restoration of the Everglades, education, the work force, and the infamous 2000 presidential election.Michael Gannon is distinguished service professor emeritus of history at the University of Florida. Among other honors, he has received the first Arthur W. Thompson Prize from the Florida Historical Society and the decoration Knight Commander of the Order of Isabel la Católica from King Juan Carlos I of Spain. He is the author of the best-selling Operation Drumbeat and editor of The New History of Florida.

    Sound familiar?"(Fritz Lanham, Houston Chronicle) Just as we do today, Americans of the 1890s faced changes in economics, politics, society, and technology that led to wrenching and sometimes violent tensions between rich and poor, capital and labor, white and black, East and West. In The Reckless Decade, H. W. Brands demonstrates that we can learn a lot about the contradictions that lie at the heart of America today by looking at them through the lens of the 1890s. The 1890s saw the closing of the American frontier and a shift toward imperialist ambitions. Populists and muckrakers grappled with robber barons and gold-bugs. Americans addressed the unfinished business of Reconstruction by separating blacks and whites. Booker T. Washington, W. E. B. Du Bois, and other black leaders clashed over the proper response to continuing racial inequality. Those on top of the economic heap—Rockefeller, Carnegie, and Morgan—created vast empires of wealth, while those at the bottom worked for dimes a day. Brands brings all this to life in a vivid narrative filled with larger-than-life characters facing momentous challenges as they worked toward an uncertain future.

    Its defeat was a reflection not only of progress in medical knowledge but of enduring changes in American social thought. Rosenberg has focused his study on New York City, the most highly developed center of this new society. Carefully documented, full of descriptive detail, yet written with an urgent sense of the drama of the epidemic years, this narrative is as absorbing for general audiences as it is for the medical historian. In a new Afterword, Rosenberg discusses changes in historical method and concerns since the original publication of The Cholera Years."A major work of interpretation of medical and social thought . . . this volume is also to be commended for its skillful, absorbing presentation of the background and the effects of this dread disease."—I.B. Cohen, New York Times"The Cholera Years is a masterful analysis of the moral and social interest attached to epidemic disease, providing generally applicable insights into how the connections between social change, changes in knowledge and changes in technical practice may be conceived."—Steven Shapin, Times Literary Supplement"In a way that is all too rarely done, Rosenberg has skillfully interwoven medical, social, and intellectual history to show how medicine and society interacted and changed during the 19th century. The history of medicine here takes its rightful place in the tapestry of human history."—John B. Blake, Science