Spelling and grammar errors go unseen after numerous reading. But then, as Bones might say, Jim, I'm a doctor, not an editor.

    The culprit--so necessary and yet the source of such upheaval--is the X chromosome, and this is its story. An enlightening and entertaining tour of the cultural and natural history of this intriguing member of the genome, "The X in Sex" traces the journey toward our current understanding of the nature of X. From its chance discovery in the nineteenth century to the promise and implications of ongoing research, David Bainbridge shows how the X evolved and where it and its counterpart Y are going, how it helps assign developing human babies their sex--and maybe even their sexuality--and how it affects our lives in infinitely complex and subtle ways. X offers cures for disease, challenges our cultural, ethical, and scientific assumptions about maleness and femaleness, and has even reshaped our views of human evolution and human nature.

    Fascinating... may presage a paradigm shift in medicine." --Kirkus Reviews (starred review)Teeming with information and big ideas... Outstanding."--Booklist (starred review) The origin of asthma, autism, Alzheimer's, allergies, cancer, heart disease, obesity, and even some kinds of depression is now clear. Award-winning researcher on the microbiome, professor Rodney Dietert presents a new paradigm in human biology that has emerged in the midst of the ongoing global epidemic of noncommunicable diseases.The Human Superorganism makes a sweeping, paradigm-shifting argument. It demolishes two fundamental beliefs that have blinkered all medical thinking until very recently: 1) Humans are better off as pure organisms free of foreign microbes; and 2) the human genome is the key to future medical advances. The microorganisms that we have sought to eliminate have been there for centuries supporting our ancestors. They comprise as much as 90 percent of the cells in and on our bodies--a staggering percentage! More than a thousand species of them live inside us, on our skin, and on our very eyelashes. Yet we have now significantly reduced their power and in doing so have sparked an epidemic of noncommunicable diseases--which now account for 63 percent of all human deaths.Ultimately, this book is not just about microbes; it is about a different way to view humans. The story that Dietert tells of where the new biology comes from, how it works, and the ways in which it affects your life is fascinating, authoritative, and revolutionary. Dietert identifies foods that best serve you, the superorganism; not new fad foods but ancient foods that have made sense for millennia. He explains protective measures against unsafe chemicals and drugs. He offers an empowering self-care guide and the blueprint for a revolution in public health. We are not what we have been taught. Each of us is a superorganism. The best path to a healthy life is through recognizing that profound truth.

    The stewards of Earth, these organisms transformed the chemistry of our planet to make it habitable for plants, animals, and us. Life's Engines takes readers deep into the microscopic world to explore how these marvelous creatures made life on Earth possible--and how human life today would cease to exist without them.Paul Falkowski looks "under the hood" of microbes to find the engines of life, the actual working parts that do the biochemical heavy lifting for every living organism on Earth. With insight and humor, he explains how these miniature engines are built--and how they have been appropriated by and assembled like Lego sets within every creature that walks, swims, or flies. Falkowski shows how evolution works to maintain this core machinery of life, and how we and other animals are veritable conglomerations of microbes.A vibrantly entertaining book about the microbes that support our very existence, Life's Engines will inspire wonder about these elegantly complex nanomachines that have driven life since its origin. It also issues a timely warning about the dangers of tinkering with that machinery to make it more "efficient" at meeting the ever-growing demands of humans in the coming century.

    Whatever your circumstances, you can create the life you desire by following simple, counterintuitive steps; not the steps society wants you to follow. Unfortunately, you cannot even trust yourself when it comes to creating the life that you desire, because you’re programmed by your past, an accumulation of hundreds of thousands of years, a mind still adapted for a hunter-gatherer time period. What does this mean? It means every day you’re battling your emotions, logic versus emotion. Logically, you want to do one thing, but emotionally, you are drawn to something else. First, if this sounds familiar, then great, because it means you are human. But, if you’re going to win the game of life, you cannot sit around and wait for things to happen, because you’ll be living a life of supreme comfort and sameness; ultimately, a great sin. You are destined for great things, capable of forging dreams and living your aspirations. Maybe you’ve forgotten about this truth: that you are capable, worthy, and ready. Maybe you’ve been beaten into the ground by life, a teacher who doesn’t care if you’re rich or poor, weak or strong, ready or not, because life will continue forward regardless, waiting for no one. Fortunately, there’re things you can do to set yourself apart from the millions that will ultimately suffer and fail. One such thing, perhaps the most powerful of all, is by studying the great, people who have succeeded and who have gone beyond what is humanly thought possible. When it comes to studying someone great, there’s one name that stands tall, Stephen Hawking, a person who has persevered and flourished. Not only has he conquered great adversity, but he has inspired millions around the world with his brilliant mind. There is a reason why people compare him with the once living Albert Einstein, the genius. What follows are Stephen Hawking’s greatest life lessons, gems of wisdom that you can easily apply to your own life, which will help you live a more abundant, stronger life. If you’re in need of inspiration, a boost of confidence, or just a friendly reminder of the wonders in life, you’ve come to the right place. See for yourself why millions study his work and regard him as a genius. Scroll up and grab your copy today.*** Limited time offer ***

    Prusiner received a Nobel Prize, the world's most prestigious award for achievement in physiology or medicine. That he was the sole recipient of the award for the year was entirely appropriate, for his struggle to identify the agent responsible for ravaging the brains of animals suffering from scrapie and mad cow disease, and of humans with Creutzfeldt-Jakob disease, had been waged largely alone and in some cases in the face of strenuous disagreement.   In this book, Prusiner tells the remarkable story of his discovery of prions—infectious proteins that replicate and cause disease but surprisingly contain no genetic material—and reveals how superb and meticulous science is actually practiced using talented teams of researchers who persevere. He recounts the frustrations and rewards of years of research and offers fascinating portraits of his peers as they raced to discover the causes of fatal brain diseases. Prusiner’s hypothesis, once considered heresy, now stands as accepted science and the basis for developing diagnoses and eventual cures. He closes with a meditation on the legacy of his discovery: What will it take to cure Alzheimer’s, Parkinson’s, Lou Gehrig’s and other devastating diseases of the brain?

    

    Some of his tales will seem far fetched, unless you're a cop and then you know that anything can happen - and just when you think you've seen it all, someone will surprise you.

    

    Among the estimated one hundred billion solar systems in the known universe, evolving life is surely abundant. That evolution is a process of becoming in each case. Since Newton, we have turned to physics to assess reality. Butphysics alone cannot tell us where we came from, how we arrived, and why our world has evolved past the point of unicellular organisms to an extremely complex biosphere.Building on concepts from his work as a complex systems researcher at the Santa Fe Institute, Kauffman focuses in particular on the idea of cells constructing themselves and introduces concepts such as constraint closure. Living systems are defined by the concept of organization which has notbeen focused on in enough in previous works. Cells are autopoetic systems that build themselves: they literally construct their own constraints on the release of energy into a few degrees of freedom that constitutes the very thermodynamic work by which they build their own self creating constraints.Living cells are machines that construct and assemble their own working parts. The emergence of such systems-the origin of life problem-was probably a spontaneous phase transition to self-reproduction in complex enough prebiotic systems. The resulting protocells were capable of Darwin's heritablevariation, hence open-ended evolution by natural selection. Evolution propagates this burgeoning organization. Evolving living creatures, by existing, create new niches into which yet further new creatures can emerge. If life is abundant in the universe, this self-constructing, propagating, exploding diversity takes us beyond physics to biospheres everywhere.

    The Golden Retriever's personality is as golden as his outer coat. He was bred to please, and please he does. He started out as a hunting partner who delivered birds to hand and has evolved into modern times delivering whatever suits his owner's fancy. Because Golden Retrievers were originally bred to work in tandem with humans, they are also highly trainable. Golden Retrievers For Dummies is intended for busy 21st century dog owners who don't have time to sit down and read through 300 pages at a crack. This is a reference you can jump in and out of as dog questions rear their furry heads. This handy guide is also for you ifYou own a Golden Retriever or thinking about getting one. You've just brought home a Golden pup. You want to find the best way to raise and train your Golden. You want to help your Golde n to not just survive but to thrive. Find out what it takes to own this active, intelligent, and friendly dog. Explore the Golden's personality traits and living requirements. Discover which diseases are hereditary. This reference guide covers all the aspects of dog ownership, including:Looking at breeders, rescue groups, and animal shelters Adopting and caring for older dogs Selecting a puppy with help from an established testing process Dog-proofing your house and yard Crate training, housetraining, and obedience training Canine communication and growing pains Feeding, exercising, and playing with your Golden Dealing with illness, problem behavior, and treatment Grooming for health and beauty If you're serious about this Golden business and not just caving in to the kids or some other wild impulse, follow the advice of responsible dog owners and breeders. Look deep into your dog-loving soul and carefully consider the big picture. Love alone is not enough.

    The New Mind Readers provides a compelling look at the origins, development, and future of these extraordinary tools, revealing how they are increasingly being used to decode our thoughts and experiences--and how this raises sometimes troubling questions about their application in domains such as marketing, politics, and the law.Russell Poldrack takes readers on a journey of scientific discovery, telling the stories of the visionaries behind these breakthroughs. Along the way, he gives an insider's perspective on what is perhaps the single most important technology in cognitive neuroscience today--functional magnetic resonance imaging, or fMRI, which is providing astonishing new insights into the contents and workings of the mind. He highlights both the amazing power and major limitations of these techniques and describes how applications outside the lab often exceed the bounds of responsible science. Poldrack also details the unique and sometimes disorienting experience of having his own brain scanned more than a hundred times as part of a landmark study of how human brain function changes over time.Written by one of the world's leading pioneers in the field, The New Mind Readers cuts through the hype and misperceptions surrounding these emerging new methods, offering needed perspective on what they can and cannot do--and demonstrating how they can provide new answers to age-old questions about the nature of consciousness and what it means to be human.

    It discusses how to plan your stargazing and what you can see with your eyes, as well as how to choose binoculars and telescopes and what you can see using them. The book also offers seasonal star charts and constellation charts and gives readers specific objects to look for in the sky. This guide from Royal Observatory Greenwich provides all you need to know to get started in stargazing and discover the universe.

    It presents the important traditional content of mineralogy including crystallography, chemical bonding, controls on mineral structure, mineral stability, and crystal growth to provide a foundation that enables students to understand the nature and occurrence of minerals. Physical, optical, and X-ray powder diffraction techniques of mineral study are described in detail, and common chemical analytical methods are outlined as well. Detailed descriptions of over 100 common minerals are provided, and the geologic context within which these minerals occur is emphasized. Appendices provide tables and diagrams to help students with mineral identification, using both physical and optical properties. Numerous line drawings, photographs, and photomicrographs help make complex concepts understandable. Introduction to Mineralogy not only provides specific knowledge about minerals but also helps students develop the intellectual tools essential for a solid, scientific education. This comprehensive text is useful for undergraduate students in a wide range of mineralogy courses.

    How is it that Homo sapiens formed such a special relationship with what, on the face of it, is a most unlikely ally? It is more than just a story of domestication but an astonishing example of the co-evolution of two species, man and wolf, to each others' mutual benefit. This co-evolution was a vital step in helping Homo sapiens overcome competition from other human species and to expand in numbers from relative obscurity on the margins towards the overwhelming numerical superiority and influence that we enjoy today. The book draws on the rich scientific detail of the genomes, both dog and human, that has accumulated over the past two decades. In each case we see a clear pattern of the origins of both species, resolving questions that have puzzled scientists for centuries. Sykes explores the breadth of this `special relationship' between man and dog. We know that dogs descend from wolves. We know that their domesticated descendants form close bonds with ourselves and there are a multitude of theories to account for our compatible social organisations. But to a geneticist, this is nowhere near powerful enough to explain this most peculiar situation. Many theories explore what it was that propelled Homo sapiens from the position of a scarce, medium-sized primate to the position of complete domination that we enjoy today. The ability to control fire, the evolution of language and the invention of agriculture are three prominent examples. Sykes crucially adds a fourth: our transformation of the wolf into the multi-purpose helpmate that is the dog. We owe our dominance and our survival to the dog.