The prolonged encounter between the Cro-Magnons and the archaic Neanderthals and between 45,000 and 30,000 years ago was one of the defining moments of history. The Neanderthals survived for some 15,000 years in the face of the newcomers, but were finally pushed aside by the Cro-Magnons' vastly superior intellectual abilities and cutting-edge technologies, which allowed them to thrive in the intensely challenging climate of the Ice Age.What do we know about this remarkable takeover? Who were the first modern Europeans and what were they like? How did they manage to thrive in such an extreme environment? And what legacy did they leave behind them after the cold millennia? The age of the Cro-Magnons lasted some 30,000 years?longer than all of recorded history. Cro-Magnon is the story of a little known, yet seminal, chapter of human experience.

    This trial serves as the backdrop for Superbugs, and the results will impact nothing less than the future of humanity.Dr. McCarthy explores the history of bacteria and antibiotics, from Alexander Fleming's discovery of penicillin, to obscure sources of innovative new medicines (often found in soil samples), to the cutting-edge DNA manipulation known as CRISPR, bringing to light how we arrived at this juncture of both incredible breakthrough and extreme vulnerability. We also meet the patients whose lives are hanging in the balance, from Remy, a teenager with a dangerous and rare infection, to Donny, a retired New York City firefighter with a compromised immune system, and many more.

    Are you the type of person who tilts at windmills, or the one who prefers to view them from the comfort of an air-conditioned motorcoach? Our personalities are endlessly fascinating—not just to ourselves but also to our spouses, our parents, our children, our co-workers, our neighbors. As a highly social species, humans have to navigate among an astonishing variety of personalities. But how did all these different permutations come about? And what purpose do they serve? With her trademark wit and sly humor, Hannah Holmes takes readers into the amazing world of personality and modern brain science. Using the Five Factor Model, which slices temperaments into the major factors (Extraversion, Neuroticism, Agreeableness, Conscientiousness, and Openness) and minor facets (such as impulsive, artistic, or cautious), Holmes demonstrates how our genes and brains dictate which factors and facets each of us displays. Are you a Nervous Nelly? Your amygdala is probably calling the shots. Hyperactive Hal? It’s all about the dopamine. Each facet took root deep in the evolution of life on Earth, with Nature allowing enough personal variation to see a species through good times and bad. Just as there are introverted and extroverted people, there are introverted and extroverted mice, and even starfish. In fact, the personality genes we share with mice make them invaluable models for the study of disorders like depression, schizophrenia, and anxiety. Thus it is deep and ancient biases that guide your dealings with a very modern world. Your personality helps to determine the political party you support, the car you drive, the way you eat M&Ms, and the likelihood that you’ll cheat on your spouse. Drawing on data from top research laboratories, the lives of her eccentric friends, the conflicts that plague her own household, and even the habits of her two pet mice, Hannah Holmes summarizes the factors that shape you. And what she proves is that it does take all kinds. Even the most irksome and trying personality you’ve ever encountered contributes to the diversity of our species. And diversity is the key to our survival.

    Contrary to what the glossy magazines would have us believe, we do not enjoy potato chips because they crunch just like the insects our forebears snacked on. As Zuk argues, such beliefs incorrectly assume that we’re stuck—finished evolving—and have been for tens of thousands of years. She draws on fascinating evidence that examines everything from adults’ ability to drink milk to the texture of our ear wax to show that we’ve actually never stopped evolving. Our nostalgic visions of an ideal evolutionary past in which we ate, lived, and reproduced as we were “meant to” fail to recognize that we were never perfectly suited to our environment. Evolution is about change, and every organism is full of trade-offs.From debunking the caveman diet to unraveling gender stereotypes, Zuk gives an analysis of widespread paleofantasies and the scientific evidence that undermines them, all the while broadening our understanding of our origins and what they can really tell us about our present and our future.

    In Missing Microbes, Dr. Martin Blaser invites us into the wilds of the human microbiome where for hundreds of thousands of years bacterial and human cells have existed in a peaceful symbiosis that is responsible for the health and equilibrium of our body. Now, this invisible eden is being irrevocably damaged by some of our most revered medical advances—antibiotics—threatening the extinction of our irreplaceable microbes with terrible health consequences. Taking us into both the lab and deep into the fields where these troubling effects can be witnessed firsthand, Blaser not only provides cutting edge evidence for the adverse effects of antibiotics, he tells us what we can do to avoid even more catastrophic health problems in the future. http://us.macmillan.com/missingmicrob...

    Both geneticists and anthropologists now generally agree that the human species originated in sub-Saharan Africa and darkly pigmented skin was the ancestral state of humanity. Moreover, worldwide human diversity is so complex that discrete races cannot be genetically defined. And for individuals, ancestry is more scientifically meaningful than race.Separate chapters are devoted to controversial topics: skin color and the scientific reasons for the differences; why ancestry is more important to individual health than race; intelligence and human diversity; and evolutionary perspectives on the persistence of racism.This is an enlightening book that goes a long way toward dispelling the irrational notions at the heart of racism.

    But to a geologist, stones are richly illustrated narratives, telling gothic tales of cataclysm and reincarnation. For more than four billion years, in beach sand, granite, and garnet schists, the planet has kept a rich and idiosyncratic journal of its past. Fulbright Scholar Marcia Bjornerud takes the reader along on an eye-opening tour of Deep Time, explaining in elegant prose what we see and feel beneath our feet. Both scientist and storyteller, Bjornerud uses anecdotes and metaphors to remind us that our home is a living thing with lessons to teach. She shows how our planet has long maintained a delicate balance, and how the global give-and-take has sustained life on Earth through numerous upheavals. But with the rapidly escalating effects of human beings on their home planet, that cosmic balance is being threatened -- and the consequences may be catastrophic. Containing a glossary and detailed timescale, as well as vivid descriptions and historic accounts, Reading the Rocks is literally a history of the world, for all friends of the Earth.

    They live everywhere—deep inside caves, 18,000 feet high in the Himalayas, inside computers, in Yellowstone’s hot springs, and in the ears and nostrils of much larger creatures. There are insects that have ears on their knees, eyes on their penises, and tongues under their feet. Most of us think life would be better without bugs. In fact, life would be impossible without them. Most of us know that we would not have honey without honeybees, but without the pinhead-sized chocolate midge, cocoa flowers would not pollinate. No cocoa, no chocolate. The ink that was used to write the Declaration of Independence was derived from galls on oak trees, which are induced by a small wasp. The fruit fly was essential to medical and biological research experiments that resulted in six Nobel prizes. Blowfly larva can clean difficult wounds; flour beetle larva can digest plastic; several species of insects have been essential to the development of antibiotics. Insects turn dead plants and animals into soil. They pollinate flowers, including crops that we depend on. They provide food for other animals, such as birds and bats. They control organisms that are harmful to humans. Life as we know it depends on these small creatures. With ecologist Anne Sverdrup-Thygeson as our capable, entertaining guide into the insect world, we’ll learn that there is more variety among insects than we can even imagine and the more you learn about insects, the more fascinating they become. Buzz, Sting, Bite is an essential introduction to the little creatures that make the world go round.

    When he emerged three years later, the summation of his efforts only hinted at what he'd experienced in one of the most dangerous regions on earth. Armed with an astonishing collection of zoological specimens, Du Chaillu leapt from the physical challenges of the jungle straight into the center of the biggest issues of the time--the evolution debate, racial discourse, the growth of Christian fundamentalism--and helped push each to unprecedented intensities. He experienced instant celebrity, but with that fame came whispers--about his past, his credibility, and his very identity--which would haunt the young man. Grand in scope, immediate in detail, and propulsively readable, Between Man and Beast brilliantly combines Du Chaillu's personal journey with the epic tale of a world hovering on the sharp edge of transformation.

    Scientists have long supported this assumption by claiming that emotions are hardwired in the body or the brain. Today, however, the science of emotion is in the midst of a revolution on par with the discovery of relativity in physics and natural selection in biology—ans this paradigm shift has far-reaching implications for us all.Leading the charge is psychologist and neuroscientist Lisa Feldman Barrett, whose theory of emotion is driving a deeper understanding of the mind and brain, and shedding new light on what it means to be human. Her research overturns the widely held belief that emotions are housed in different parts of the brain and are universally expressed and recognized. Instead, she has shown that emotion is constructed in the moment, by core systems that interact across the whole brain, aided by a lifetime of learning. This new theory means that you play a much greater role in your emotional life than you ever thought. Its repercussions are already shaking the foundations not only of psychology but also of medicine, the legal system, child-rearing, meditation, and even airport security.Why do emotions feel automatic? Does rational thought really control emotion? How does emotion affect disease? How can you make your children more emotionally intelligent? How Emotions Are Made answers these questions and many more, revealing the latest research and intriguing practical applications of the new science of emotion, mind, and brain.

    But Maurice Hilleman came close. Maurice Hilleman is the father of modern vaccines. Chief among his accomplishments are nine vaccines that practically every child gets, rendering formerly deadly diseases — including mumps, rubella, and measles — nearly forgotten. Author Paul A. Offit's rich and lively narrative details Hilleman's research and experiences as the basis for a larger exploration of the development of vaccines, covering two hundred years of medical history and traveling across the globe in the process. The history of vaccines necessarily brings with it a cautionary message, as they have come under assault from those insisting they do more harm than good. Paul Offit clearly and compellingly rebuts these arguments, and, by demonstrating how much the work of Hilleman and others has gained for humanity, shows us how much we have to lose.

    In Papua New Guinea, a primitive tribe is nearly obliterated by a sickness whose chief symptom is uncontrollable laughter. Across Europe, millions of sheep rub their fleeces raw before collapsing. In England, cows attack their owners in the milking parlors, while in the American West, thousands of deer starve to death in fields full of grass.What these strange conditions–including fatal familial insomnia, kuru, scrapie, and mad cow disease–share is their cause: prions. Prions are ordinary proteins that sometimes go wrong, resulting in neurological illnesses that are always fatal. Even more mysterious and frightening, prions are almost impossible to destroy because they are not alive and have no DNA–and the diseases they bring are now spreading around the world.In The Family That Couldn’t Sleep, essayist and journalist D. T. Max tells the spellbinding story of the prion’s hidden past and deadly future

    Here are astounding animals of every stripe: Dung beetles that steer by the light of the Milky Way. Ants and bees that rely on patterns of light invisible to humans. Sea turtles and moths that find their way using Earth’s magnetic field. Humpback whales that swim thousands of miles while holding a rocksteady course. Birds that can locate their nests on a tiny island after crisscrossing an ocean.The age of viewing animals as unthinking drones is over. As Supernavigators makes clear, a stunning array of species command senses and skills—and arguably, types of intelligence—beyond our own. Weaving together interviews with leading animal behaviorists and the groundbreaking discoveries of Nobel Prize–winning scientists, David Barrie reveals these wonders in a whole new light.

    In The Compatibility Gene, one of our foremost immunologists tells the remarkable history of these genes' discovery and the unlocking of their secrets. Davis shows how the compatibility gene is radically transforming our knowledge of the way our bodies work - and is having profound consequences for medical research and ethics. Looking to the future, he considers the startling possibilities of what these wondrous discoveries might mean for you and me.

    With numerous black-and-white images and eight pages of color plates, The Lives of Ants provides a state-of-the-art look at what we now know about these fascinating creatures, portraying a world that is rich and full of surprises, one which, even after decades of observation, is still full of unsolved mysteries.The authors illuminate the world of the ant, shedding light on such topics as the ant's impressive abilities in direction finding and quite amazing ingenuity when it comes to building their nests, finding supplies, or exploiting other members of the animal kingdom. They show, too, that they are capable of aggression and violence, which can disturb the apparent peace of their colonies and embroil them in fratricidal or matricidal strife. Even their sexual arrangements are at times quite strange. In this area, as in many others, they display marked originality. Readers also discover that ants are walking bundles of secretory glands (they have about forty of them), which enable them to emit between ten and twenty different pheromones, each of which has its own "meaning." Some are produced by workers for recruiting their sisters or for alerting them to danger. Others are used for marking territory, for identifying members of their colony or conversely for detecting foreigners, and for indicating the location of food. In addition, ants can also emit sound signals, made of a high-pitched squeak, and they can even dance, though not as intricately or as well as bees.The Lives of Ants combines natural history with molecular biology, genetics, and even the latest developments in robotics, to explore the remarkable societies of ants, revealing the secrets of their mysterious lives.