Increased emphasis on gene activity, signal transduction and the emphasis on the roles of paracrine factors in development.

    Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with - and perished from - for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. From the Persian Queen Atossa, whose Greek slave cut off her malignant breast, to the nineteenth-century recipients of primitive radiation and chemotherapy to Mukherjee’s own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through fiercely demanding regimens in order to survive—and to increase our understanding of this iconic disease. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

    As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his co-discovery of the structure of DNA. She and her collaborators turned ​a curiosity ​of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020.

    The planet is full of millions of species of plants, birds, animals, and microbes, and every single one -- including us -- is part of a big, beautiful, complicated pattern. When humans interfere with parts of the pattern, by polluting the air and oceans, taking too much from the sea, and cutting down too many forests, animals and plants begin to disappear. What sort of world would it be if it went from having many types of living things to having just one? In a beautiful follow-up, the creators of the award-winning Tiny Creatures: The World of Microbes deliver an inspiring look at the extraordinary diversity of Earth's inhabitants -- and the importance of their preservation.

    David Horowitz’s classic Why Israel is the Victim, updated by the author, sets the record straight about the basic truths of the Middle East conflict. In addition to restoring the authentic history of the region – a history of obsessive aggression first by Arab countries determined to physically annihilate the Jewish State and later by terror groups determined to destroy its will to survive and right to exist—this booklet brings the story up to date by showing the systematic way in which Hamas and Hezbollah, under Iran’s direction, have subverted peace in the Middle East. As Shillman Fellow Daniel Greenfield notes in his insightful introduction, this pamphlet “tells us why we should reject the “Blame Israel First” narrative that has so thoroughly saturated the mainstream media… It confronts the myth of Palestinian victimhood… and it delivers a rousing restatement of the true history of the hate that led us to all this.” America should be Israel’s protector. Instead, as David Horowitz notes, under the leadership of Barack Obama, it has become its prosecutor.

    Created through a "student-tested, faculty-approved" review process with over 150 students and faculty, PSYCH 2 is an engaging and accessible solution to accommodate the diverse lifestyles of today's learners.

    Its presence in nature was dismissed as a desperate response to starvation or other life-threatening circumstances, and few spent time studying it. A taboo subject in our culture, the behavior was portrayed mostly through horror movies or tabloids sensationalizing the crimes of real-life flesh-eaters. But the true nature of cannibalism--the role it plays in evolution as well as human history--is even more intriguing (and more normal) than the misconceptions we've come to accept as fact. In Cannibalism: A Perfectly Natural History, zoologist Bill Schutt sets the record straight, debunking common myths and investigating our new understanding of cannibalism's role in biology, anthropology, and history in the most fascinating account yet written on this complex topic. Schutt takes readers from Arizona's Chiricahua Mountains, where he wades through ponds full of tadpoles devouring their siblings, to the Sierra Nevadas, where he joins researchers who are shedding new light on what happened to the Donner Party--the most infamous episode of cannibalism in American history. He even meets with an expert on the preparation and consumption of human placenta (and, yes, it goes well with Chianti). Bringing together the latest cutting-edge science, Schutt answers questions such as why some amphibians consume their mother's skin; why certain insects bite the heads off their partners after sex; why, up until the end of the twentieth century, Europeans regularly ate human body parts as medical curatives; and how cannibalism might be linked to the extinction of the Neanderthals. He takes us into the future as well, investigating whether, as climate change causes famine, disease, and overcrowding, we may see more outbreaks of cannibalism in many more species--including our own.Cannibalism places a perfectly natural occurrence into a vital new context and invites us to explore why it both enthralls and repels us.

    Its unique 'Frontiers' chapters cover materials science, nanotechnology, catalysis, and biological inorganic chemistry, and have been fully updated to reflect advances in these key areas of contemporary research and industrial application.