In 1919, Spanish flu killed over 50 million people, more than died in both world wars combined. In 1950, an estimated 50 million people caught smallpox worldwide, of whom 10 million died. In 1980, before measles vaccine was widely used, an estimated 2.6 million children died of measles every year. Today we are hostage to a new pandemic disease -the seemingly unstoppable COVID-19.Less than 100 years ago, losing a child to an infection like diphtheria or polio was a dreaded but almost inevitable sorrow faced by all parents, from the richest to the poorest. Today, these killer diseases are almost never seen in industrialised countries, thanks to the development of vaccines. Immunisation has given modern parents peace of mind their ancestors could not imagine.The history of vaccination is rich with trial, error, sabotage and success. It encompasses the tragedy of lives lost, the drama of competition and discovery, the culpability of botched testing, and the triumph of effective, lifelong immunity. Yet with the eradication in the first world of some of humanity's deadliest foes, complacency in some quarters has set in. COVID-19 has us again racing for a vaccine. The story of past achievements and failures helps us keep the race - and the hope - in perspective.This is a book for everyone who wants to understand our past - and cares about our future.PRAISE'Anyone who has doubts about the life-saving miracle of vaccination should read this' Steven Carroll, Sydney Morning Herald'An entertaining and engaging work that is sure to delight general readers' Australian Book Review'The ideal handbook for pregnant women, parents, travellers, childcare and aged-care workers, GPs and anyone with an interest in public health' The Australian'Isaacs explores the understanding of immunity as it develops from the fifth century BC to the present day and thrills us with the progressive successes of each of the 14 vaccines which a child routinely receives today ... The work is authoritative, beguiling, amusing, instructive and inspirational. It deserves a wide readership, including infectious disease experts, other health professionals and, most assuredly, a diversity of lay people' Sir Gustav Nossal, immunologist and director of The Walter and Eliza Institute of Medical Research, Melbourne, 1965-1996'A rollicking story of human endeavour, error, misinformation, success and failure ... and more than a glimpse of why we need to continue to research, evaluate, educate and fund vaccines to prevent disease' Fiona Stanley, Distinguished Research Professor, University of Western Australia'Effortlessly accessible, Defeating the Ministers of Death brilliantly reveals the people behind the most important public health intervention in history' Professor Andrew J Pollard, Department of Paediatrics, University of Oxford'This book is an unflinching look at the triumphs and inevitable tragedies in the war against infectious diseases. Nonfiction is at its best when it reads like fiction. And David Isaacs has written a page turner' Paul A. Offit, MD, author of Bad Advice: Or Why Celebrities, Politicians, and Activists Aren't Your Best Source of Health Information

    The most trusted sources in the auto industry have called its Model S the most advanced, safest and best-performing car ever built - and it doesn’t use a drop of gasoline. Tesla has changed the way the public perceives electric vehicles, and inspired the major automakers to revive their own dormant efforts to sell EVs. However, even amidst the avalanche of media coverage that followed the triumph of the Model S, few have grasped the true significance of what is happening. Tesla has redefined the automobile, sparked a new wave of innovation comparable to the internet and mobile computing revolutions, and unleashed forces that will transform not just the auto industry, but every aspect of society. The Tesla story is one part of an ongoing tide of change driven by the use of information technology to eliminate “friction” such as geographic distance, middlemen and outdated regulations. Tesla is simply applying the new order to the auto industry, but the automobile is such a pervasive influence in our lives that redefining how it is designed, built, driven and sold will have sweeping effects in unexpected areas. Just as Tesla built the Model S as an electric vehicle “from the ground up,” it has taken an outsider’s approach to the way it markets its cars. Its direct sales model has drawn legal challenges from entrenched auto dealers, who fear that their outdated business model will be destroyed. Its systems approach to the software and electronics in its cars has highlighted how far behind the technological times the major automakers are. It’s easy to see why readers find Tesla irresistible. CEO Elon Musk is a superstar entrepreneur, a “nauseatingly pro-US” immigrant and the leader of two other cutting-edge companies. Tesla dares to challenge the establishment behemoths and, so far at least, has handily beaten them at their own game. In this history of the 21st century’s most exciting startup, Charles Morris begins with a brief history of EVs and a biography of Tesla’s driving force, Elon Musk. He then details the history of the company, told in the words of the Silicon Valley entrepreneurs who made it happen. There are many fascinating stories here: Martin Eberhard’s realization that there were many like himself, who loved fast cars but wanted to help the environment and bring about the post-oil age; the freewheeling first days, reminiscent of the early internet era; the incredible ingenuity of the team who built the Roadster; Tesla’s near-death experience and miraculous resurrection; the spiteful split between the company’s larger-than-life leaders; the gloves-off battles with hostile media such as Top Gear and the New York Times; and the media’s ironic about-face when the magnificent Model S won the industry’s highest honors, and naysayers became cheerleaders overnight. And the story is just beginning: Tesla has breathtakingly ambitious plans for the future.This book was updated May 1, 2015 to include the latest on the Gigafactory and the D package.

    Read all about these fantastic facts--and dozens of others--in this fun-to-read book.Did you know that some pioneers took a "shortcut" to Oregon that took them perilously close to Antarctica? Or that ferryboat operators on the Oregon Trail could earn nearly $2,000 per day? Or that many pioneers found ice in the middle of the blazing hot desert? It's all true! An entertaining read for young people or anyone interested in the great western journey.

    The age-old disease spread swiftly through an increasingly interconnected American landscape: from southern tobacco plantations to the dense immigrant neighborhoods of northern cities to far-flung villages on the edges of the nascent American empire. In Pox, award-winning historian Michael Willrich offers a gripping chronicle of how the nation's continentwide fight against smallpox launched one of the most important civil liberties struggles of the twentieth century.At the dawn of the activist Progressive era and during a moment of great optimism about modern medicine, the government responded to the deadly epidemic by calling for universal compulsory vaccination. To enforce the law, public health authorities relied on quarantines, pesthouses, and "virus squads"-corps of doctors and club-wielding police. Though these measures eventually contained the disease, they also sparked a wave of popular resistance among Americans who perceived them as a threat to their health and to their rights.At the time, anti-vaccinationists were often dismissed as misguided cranks, but Willrich argues that they belonged to a wider legacy of American dissent that attended the rise of an increasingly powerful government. While a well-organized anti-vaccination movement sprang up during these years, many Americans resisted in subtler ways-by concealing sick family members or forging immunization certificates. Pox introduces us to memorable characters on both sides of the debate, from Henning Jacobson, a Swedish Lutheran minister whose battle against vaccination went all the way to the Supreme Court, to C. P. Wertenbaker, a federal surgeon who saw himself as a medical missionary combating a deadly-and preventable-disease.As Willrich suggests, many of the questions first raised by the Progressive-era antivaccination movement are still with us: How far should the government go to protect us from peril? What happens when the interests of public health collide with religious beliefs and personal conscience? In Pox, Willrich delivers a riveting tale about the clash of modern medicine, civil liberties, and government power at the turn of the last century that resonates powerfully today.

    If you read one book on human origins, this should be it' Ian Morris, author of Why the West Rules - For Now 'The who, what, where, when and how of human evolution, from one of the world's experts on the dating of prehistoric fossils' Steve Brusatte, author of The Rise and Fall of the Dinosaurs50,000 years ago, we were not the only species of human in the world. There were at least four others, including the Neanderthals, Homo floresiensis, Homo luzonesis and the Denisovans. At the forefront of the latter's ground-breaking discovery was Oxford Professor Tom Higham. In The World Before Us, he explains the scientific and technological advancements - in radiocarbon dating and ancient DNA, for example - that allowed each of these discoveries to be made, enabling us to be more accurate in our predictions about not just how long ago these other humans lived, but how they lived, interacted and live on in our genes today. This is the story of us, told for the first time with its full cast of characters.'The application of new genetic science to pre-history is analogous to how the telescope transformed astronomy. Tom Higham brings us to the frontier of recent discoveries with a book that is both gripping and fun' Paul Collier, author of The Bottom Billion'This exciting book shows that we now have a revolutionary new tool for reconstructing the human past: DNA from minute pieces of tooth and bone, and even from the dirt on the floor of caves' David Abulafia, author of The Boundless Sea'The remarkable new science of palaeoanthropology, from lab bench to trench' Rebecca Wragg Sykes, author of Kindred'Higham's thrilling account makes readers feel as if they were participating themselves in the extraordinary series of events that in the last few years has revealed our long-lost cousins' David Reich, author of Who We Are and How We Got Here'A brilliant distillation of the ideas and discoveries revolutionising our understanding of human evolution' Chris Gosden, author of The History of Magic

    In the studio Louise unexpectedly finds freedom to be herself. But someone has been watching her every move...

    Humans: from the beginning will appeal to anybody who reads about these discoveries, is intrigued by them, and would like to know more about prehistory. Now brought fully up to date for 2015, Humans: from the beginning is a single-volume guide to the human past. Drawing upon expert literature and the latest multi-disciplinary research, this rigorous but accessible book traces the whole of the human story from the first apes to the first cities. The end product of five years of research, it has also been planned from the ground up to take advantage of the eBook format and ease access to visual matter, references and glossary items. Humans: from the beginning is written for the non-specialist, but it is sufficiently comprehensive in scope, rigorous in content, and well-referenced to serve as an ideal ‘one-stop’ text not only for undergraduate students of relevant disciplines, but also to postgraduates, researchers and other academics seeking to broaden their knowledge. This 32-chapter work presents an even-handed coverage of topics including: • How climate change has long played a pivotal role in our affairs and those of our ancestors. • How humans evolved from apes at a time when the apes were facing extinction. • Why the last common ancestor of humans and chimpanzees (our closest living relatives) might have been more like a human than a chimpanzee. • A possible Asian rather than African origin for the earliest humans. • Why the Neanderthals were not the dimwits of popular imagination. • How language and modern human behaviour evolved: an examination of theories including those of Robin Dunbar, Steven Mithen and Derek Bickerton. • How the small group of modern humans that eventually colonised the whole of the non-African world might have started from Arabia rather than Africa. • David Lewis-Williams’ theory that the cave art of Ice Age Europe was linked to a shamanistic belief system that might be rooted in the very architecture of the human brain. • Why the Neolithic transition from hunter-gathering to agriculture was a lengthy process, with many down sides. • Colin Renfrew’s still-controversial theory that the spread of farming communities in Neolithic times was responsible for the languages now spoken in many parts of the world. • How an ‘Urban Revolution’ replaced egalitarian farming communities with socially-stratified kingdoms and city-states in just a few millennia. • How the complex, technological societies of today have much in common with not only the earliest states but much earlier primate societies.

    Today, more than sixty years later, members of a new generation of scientists are attempting to create life from the ground up. Science has moved forward in leaps and bounds since Schrodinger's time, but our understanding of what does and does not constitute life has only grown more complex. An era that has already seen computer chip-implanted human brains, genetically engineered organisms, genetically modified foods, cloned mammals, and brain-dead humans kept alive by machines is one that demands fresh thinking about the concept of life. While a segment of our national debate remains stubbornly mired in moral quandaries over abortion, euthanasia, and other right to life issues, the science writer Ed Regis demonstrates how science can and does provide us with a detailed understanding of the nature of life. Written in a lively and accessible style, and synthesizing a wide range of contemporary research, What Is Life? is a brief and illuminating contribution to an age-old debate.

    A defiant atheist, Chapman is confronted not only by the fundamentalist beliefs that continue to banish the theory of evolution but by his own spiritual malaise as the outward journey becomes an inward quest, a tragicomic "accidental memoir"."First there was Charles Darwin, two yards long and nobody's fool. Then there was his son, my great-grandfather, Sir Francis Darwin, an eminent botanist. Then came my grandmother Frances, a modest poet who spent a considerable amount of time in rest-homes for depression From her issued my beloved mother, Clare, who was extremely short, failed to complete medical school, and eventually became an alcoholic. Then we get down to me. I'm in the movie business."Trials of the Monkey combines travel writing and reportage, as Chapman records his encounters in the South, with history and the accidental memoir of a man full of mid-life doubts in a genre-breaking first book that is darkly funny, provocative and poignant.

     In this masterful account of the 1995 Ebola outbreak in Zaire, Garrett, now the Senior Fellow for Global Health at the Council on Foreign Relations, shows how superstition and fear, compounded by a lack of resources, education, and clearheaded government planning have plagued our response to Ebola. In an extensive new introduction, Garrett forcefully argues that learning from past outbreaks is the key to solving the Ebola crisis of 2014. In her account of the 1995 Zaire outbreak, first published in her bestselling book Betrayal of Trust, Garrett takes readers through the epidemic's course-beginning with the Kikwit villager who first contracted it from an animal encounter while chopping wood for charcoal deep in the forest. As she documents the outbreak in riveting detail, Garrett shows why our trust in world governments to protect people's health has been irrevocably broken. She details the international community's engagement in the epidemic's aftermath: a pattern of response and abandonment, urgency that devolves into amnesia. Ebola: Story of an Outbreak is essential reading for anyone who wants to comprehend Ebola, one of mankind's most mysterious, malicious scourges. Garrett has issued a powerful call for governments, citizens, and the disease-fighting agencies of the wealthy world to take action.

    But there is one other crucial factor, which is much less well known. The same team had done it before. The truth is that many of those most closely involved in cracking the Enigma code – Alistair Denniston, Frank Birch, Dilly Knox – had wrestled with German naval codes for most of the First World War. By the end of the war they had been successfully cracking a new code every day, from their secret Room 40 at the Old Admiralty Building, in a London blacked out for Zeppelin Raids.The techniques they developed then, the ideas that they came to rely on, the people they came to trust, had been developed the hard way, under intense pressure and absolute secrecy during World War I. Before Enigma tells their story and explains how they managed to crack the supposedly indecipherable code. The book outlines the capture of the Magdeburg and the Hobart, discusses the use of cracked codes to bring German fleets to battle at Dogger Bank and Jutland, and focuses on individuals such as Winston Churchill and Admiral Sir Reginald ‘Blinker’ Hall and their importance in the development of a British naval code tradition. Praise for David Boyle ‘Exhilarating’ - Daily Mail David Boyle is a British author and journalist who writes mainly about history and new ideas in economics, money, business and culture. He lives in Crystal Palace, London. His books include Alan Turing: Unlocking the Enigma, Operation Primrose, Rupert Brooke: England’s Last Patriot, Peace on Earth: The Christmas Truce of 1914, Jerusalem: England’s National Anthem and Unheard Unseen: Warfare in the Dardanelles .Endeavour Press is the UK's leading independent digital publisher. For more information on our titles please sign up to our newsletter at www.endeavourpress.com. Each week you will receive updates on free and discounted ebooks. Follow us on Twitter: @EndeavourPress and on Facebook via http://on.fb.me/1HweQV7. We are always interested in hearing from our readers. Endeavour Press believes that the future is now.

    In his delightfully down-to-earth style, he explores & explains a mind-boggling future of intelligent robots, extraterrestrial life & its consquences, & other provocative, fascinating quandries of the future we want to see today.

    Only 17 when he enlisted in 1964, Johnson deployed to Vietnam with the 3rd Reconnaissance Battalion, 3rd Marine Division, and his tour included such now famous locations as Phu Bai, Khe Sanh, Nha Trang and Quang Tri, among others. With a sometimes humorous tone, Johnson describes a war of often terrified high school and college-aged youngsters faced with exotic plant and animal life, monsoon rains, harrowing reconnaissance missions and death. Details are plentiful about tactics, equipment, geography and, always, fellow Marines.

    There are tranquil tropical harbours and violent storms far from shore. We are in the wireless room when ships are calling for help. The story begins with humble origins on the coast of County Durham surrounded by family still coming to terms with the Great War. The author's father went to war on horseback, yet in this story we are on the brink of the modern world. The writer was fortunate to join the Merchant Navy in the 1950s, and know its most glorious days. Harry Nicholson now lives near Whitby, on the Yorkshire coast. His other books are Tom Fleck, a Tudor novel of Cleveland and Flodden, and its sequel The Black Caravel. His collected poetry is suitably titled, Wandering About.

    military conducted on President’s Kennedy’s body on the night of November 22, 1963. Hornberger’s new book, The Kennedy Autopsy 2, expands on his earlier work. In this new book, you will learn: The important role that Lyndon Johnson played in the U.S. military’s fraudulent autopsy on the president’s body. The significance of various meetings at the National Archives prior to the 1968 presidential race, where autopsy pathologists signed false affidavits relating to the inventory of autopsy photographs. An alternative explanation as to why Johnson suddenly decided to drop out of the 1968 presidential race. How and why Lee Harvey Oswald escaped the U.S. government’s Cold War anticommunist crusade. And much more.