Roy Porter's historical overview of madness reveals the radically different perceptions of madness and approaches to its treatment, from antiquity to the beginning of the 21st century.Looking back on his confinement to Bethlem, Restoration playwright Nathaniel Lee declared: "They called me mad, and I called them mad, and damn them, they outvoted me." As Roy Porter shows in Madness: A Brief History, thinking about who qualifies as insane, what causes mental illness, and how such illness should be treated has varied wildly throughout recorded history, sometimes veering dangerously close to the arbitrariness Lee describes and often encompassing cures considerably worse than the illness itself.Drawing upon eyewitness accounts of doctors, writers, artists, and the mad themselves, Roy Porter tells the story of our changing notions of insanity and of the treatments for mental illness that have been employed from antiquity to the present day. Beginning with 5,000-year-old skulls with tiny holes bored in them (to allow demons to escape), through conceptions of madness as an acute phase in the trial of souls, as an imbalance of "the humors," as the "divine fury" of creative genius, or as the malfunctioning of brain chemistry, Porter shows the many ways madness has been perceived and misperceived in every historical period. He takes us on a fascinating round of treatments, ranging from exorcism and therapeutic terror--including immersion in a tub of eels--to the first asylums, shock therapy, the birth of psychoanalysis, and the current use of psychotropic drugs.Throughout, Madness: A Brief History offers a balanced view, showing both the humane attempts to help the insane as well as the ridiculous and often cruel misunderstanding that have bedeviled our efforts to heal the mind of its myriad afflictions.

    It was a sea in name only. It was actually a bone dry, ancient dusty basin pockmarked with craters and littered with rocks and boulders. Somewhere in that 500 mile diameter basin, the astronauts would attempt to make Mankind’s first landing on the Moon. Neil Armstrong would pilot the Lunar Module “Eagle” during its twelve minute descent from orbit down to a landing. Col. Edwin “Buzz” Aldrin would assist him. On the way down they would encounter a host of problems, any one of which could have potentially caused them to have to call off the landing, or, even worse, die making the attempt. The problems were all technical-communications problems, computer problems, guidance problems, sensor problems. Armstrong and Aldrin faced the very real risk of dying by the very same technical sword that they had to live by in order to accomplish the enormous task of landing on the Moon for the first time. Yet the human skills Armstrong and Aldrin employed would be more than equal to the task. Armstrong’s formidable skills as an aviator, honed from the time he was a young boy, would serve him well as he piloted Eagle down amidst a continuing series of systems problems that might have fatally distracted a lesser aviator. Armstrong’s brilliant piloting was complemented by Aldrin’s equally remarkable discipline and calmness as he stoically provided a running commentary on altitude and descent rate while handling systems problems that threatened the landing. Finally, after a harrowing twelve and a half minutes, Armstrong gently landed Eagle at “Tranquility Base”, a name he had personally chosen to denote the location of the first Moon landing. In “Landing Eagle-Inside the Cockpit During the First Moon Landing”, author Mike Engle gives a minute by minute account of the events that occurred throughout Eagle’s descent and landing on the Moon. Engle, a retired NASA engineer and Mission Control flight controller, uses NASA audio files of actual voice recordings made inside Eagle’s cockpit during landing to give the reader an “inside the cockpit” perspective on the first Moon landing. Engle’s transcripts of these recordings, along with background material on the history and technical details behind the enormous effort to accomplish the first Moon landing, give a new and fascinating insight into the events that occurred on that remarkable day fifty years ago.

    Biologists have been trying to solve the mystery of how organisms have the ability to migrate and orient with such precision—especially since our own adventurous ancestors spread across the world without maps or instruments. O'Connor goes to the Arctic, the Australian bush, and the South Pacific to talk to masters of their environment who seek to preserve their traditions at a time when anyone can use a GPS to navigate.O'Connor explores the neurological basis of spatial orientation within the hippocampus. Without it, people inhabit a dream state, becoming amnesiacs incapable of finding their way, recalling the past, or imagining the future. Studies have shown that the more we exercise our cognitive mapping skills, the greater the grey matter and health of our hippocampus. O'Connor talks to scientists studying how atrophy in the hippocampus is associated with afflictions such as impaired memory, dementia, Alzheimer's Disease, depression, and PTSD.Wayfinding is a captivating book that charts how our species' profound capacity for exploration, memory, and storytelling results in topophilia, the love of place.

    In 1985 Hans von Ohain, the scientist who pioneered Nazi Germany's efforts to build a jet plane, posed the question: 'Would World War II have occured if the Luftwaffe knew it faced operational British jets instead of Spitfires?' He immediately answered, 'I, for one, think not.'Frank Whittle, working-class outsider and self-taught enthusiast, had worked out the blueprint of a completely new type of engine in 1929, only for his ideas to be blocked by bureaucratic opposition until the outbreak of war in 1939. The importance of his work was recognized too late by the government for his revolutionary engine to play a major part in World War II. After the war Whittle's dream of civilian jet-powered aircraft became a reality and Britain enjoyed a golden age of 1950's jet-powered flight.Drawing on Whittle's extensive private papers, Campbell-Smith tells the story of a stoic and overlooked British hero, a tantalizing tale of 'what might have been'.

    A young surgeon is drafted into the U.S. Navy and sent to Vietnam, where he finds himself closer than he ever imagined to the carnage of war. He performs operations while under fire and sees wounds that can barely be contemplated. Marines are dying on the operating table in front of him. The small-town moral certainties he grew up believing in may themselves succumb to the ravages he is witnessing. More than anything, he wants to make it home to marry the woman he loves.

    The struggle for reconciliation between the contending forces is not an easy one. It cuts deep into the soul and usually leaves scars that ache while life endures. There are thousands of young people in the Church to-day, and hundreds of thousands throughout the world, who are struggling to set themselves right with the God above and the world about them. It is for these young people, primarily, that the following chapters have been written...

    Told here for the first time, the dramatic tale of how the secrets of the brain were discovered in seventeenth-century England unfolds against a turbulent backdrop of civil war, the Great Fire of London, and plague. At the beginning of that chaotic century, no one knew how the brain worked or even what it looked like intact. But by the century's close, even the most common conceptions and dominant philosophies had been completely overturned, supplanted by a radical new vision of man, God, and the universe. Presiding over the rise of this new scientific paradigm was the founder of modern neurology, Thomas Willis, a fascinating, sympathetic, even heroic figure at the center of an extraordinary group of scientists and philosophers known as the Oxford circle. Chronicled here in vivid detail are their groundbreaking revelations and the often gory experiments that first enshrined the brain as the physical seat of intelligence -- and the seat of the human soul. Soul Made Flesh conveys a contagious appreciation for the brain, its structure, and its many marvelous functions, and the implications for human identity, mind, and morality.

    Nobody is perfect. And that includes five of the greatest scientists in history—Charles Darwin, William Thomson (Lord Kelvin), Linus Pauling, Fred Hoyle, and Albert Einstein. But the mistakes that these great luminaries made helped advance science. Indeed, as Mario Livio explains, science thrives on error, advancing when erroneous ideas are disproven.As a young scientist, Einstein tried to conceive of a way to describe the evolution of the universe at large, based on General Relativity—his theory of space, time, and gravity. Unfortunately he fell victim to a misguided notion of aesthetic simplicity. Fred Hoyle was an eminent astrophysicist who ridiculed an emerging theory about the origin of the universe that he dismissively called “The Big Bang.” The name stuck, but Hoyle was dead wrong in his opposition.They, along with Darwin (a blunder in his theory of Natural Selection), Kelvin (a blunder in his calculation of the age of the earth), and Pauling (a blunder in his model for the structure of the DNA molecule), were brilliant men and fascinating human beings. Their blunders were a necessary part of the scientific process. Collectively they helped to dramatically further our knowledge of the evolution of life, the Earth, and the universe.

    But Maurice Hilleman came close. Maurice Hilleman is the father of modern vaccines. Chief among his accomplishments are nine vaccines that practically every child gets, rendering formerly deadly diseases — including mumps, rubella, and measles — nearly forgotten. Author Paul A. Offit's rich and lively narrative details Hilleman's research and experiences as the basis for a larger exploration of the development of vaccines, covering two hundred years of medical history and traveling across the globe in the process. The history of vaccines necessarily brings with it a cautionary message, as they have come under assault from those insisting they do more harm than good. Paul Offit clearly and compellingly rebuts these arguments, and, by demonstrating how much the work of Hilleman and others has gained for humanity, shows us how much we have to lose.

    However, for every victory, there are no doubt numerous little-known blunders. Neuroscientist Simon LeVay brings together a collection of fascinating, yet shocking, stories of failure from recent scientific history in When Science Goes Wrong.From the fields of forensics and microbiology to nuclear physics and meteorology, in When Science Goes Wrong LeVay shares twelve true essays illustrating a variety of ways in which the scientific process can go awry. Failures, disasters and other negative outcomes of science can result not only from bad luck, but from causes including failure to follow appropriate procedures and heed warnings, ethical breaches, quick pressure to obtain results, and even fraud. Often, as LeVay notes, the greatest opportunity for notable mishaps occurs when science serves human ends. LeVay shares these examples:To counteract the onslaught of Parkinson's disease, a patient undergoes cutting-edge brain surgery using fetal transplants, and is later found to have hair and cartilage growing inside his brain.In 1999, NASA's Mars Climate Orbiter spacecraft is lost due to an error in calculation, only months after the agency adopts a policy of "Faster, Better, Cheaper."Britain's Bracknell weather forecasting team predicts two possible outcomes for a potentially violent system, but is pressured into releasing a 'milder' forecast. The BBC's top weatherman reports there is "no hurricane," while later the storm hits, devastating southeast England.Ignoring signals of an imminent eruption, scientists decide to lead a party to hike into the crater of a dormant volcano in Columbia, causing injury and death.When Science Goes Wrong provides a compelling glimpse into human ambition in scientific pursuit.

    With plenty of engaging material, practice questions, and practical ideas, this updated edition contains everything your students need to succeed in Cambridge IGCSE biology.

    The germ revolution came after two decades of scientific virtuosity, outstanding feats of intellectual courage and bitter personal rivalries, doctors at last recognised that infectious diseases are caused by mircoscopic organisms.

    David Schneider’s The Invention of Surgery is an in-depth biography of the practice that has leapt forward over the centuries from the dangerous guesswork of ancient Greek physicians through the world-changing “implant revolution” of the twentieth century.The Invention of Surgery explains this dramatic progress and highlights the personalities of the discipline's most dynamic historical figures. It links together the lives of the pioneering scientists who first understood what causes disease, how organs become infected or cancerous, and how surgery could powerfully intercede in people’s lives, and then shows how the rise of surgery intersected with many of the greatest medical breakthroughs of the last century, including the evolution of medical education, the transformation of the hospital from a place of dying to a habitation of healing, the development of antibiotics, and the rise of transistors and polymer science.And as Schneider argues, surgery has not finished transforming; new technologies are constantly reinventing both the practice of surgery and the nature of the objects we are permanently implanting in our bodies. Schneider considers these latest developments, asking “What’s next?” and analyzing how our conception of surgery has changed alongside our evolving ideas of medicine, technology, and our bodies.

    Ultimately, the history of these challenges tells the story of humanity itself. Through an unforgettable cast of characters, Pulitzer Prize-winning author Richard Rhodes explains how wood gave way to coal and coal made room for oil, as we now turn to natural gas, nuclear power, and renewable energy. Rhodes looks back on five centuries of progress, through such influential figures as Queen Elizabeth I, King James I, Benjamin Franklin, Herman Melville, John D. Rockefeller, and Henry Ford. In Energy, Rhodes highlights the successes and failures that led to each breakthrough in energy production; from animal and waterpower to the steam engine, from internal-combustion to the electric motor. He addresses how we learned from such challenges, mastered their transitions, and capitalized on their opportunities. Rhodes also looks at the current energy landscape, with a focus on how wind energy is competing for dominance with cast supplies of coal and natural gas. He also addresses the specter of global warming, and a population hurtling towards ten billion by 2100. Human beings have confronted the problem of how to draw life from raw material since the beginning of time. Each invention, each discovery, each adaptation brought further challenges, and through such transformations, we arrived at where we are today. In Rhodes’s singular style, Energy details how this knowledge of our history can inform our way tomorrow.

    It's also a book full of entertainment and wonders. In The Song of the Dodo, we follow Quammen's keen intellect through the ideas, theories, and experiments of prominent naturalists of the last two centuries. We trail after him as he travels the world, tracking the subject of island biogeography, which encompasses nothing less than the study of the origin and extinction of all species. Why is this island idea so important? Because islands are where species most commonly go extinct -- and because, as Quammen points out, we live in an age when all of Earth's landscapes are being chopped into island-like fragments by human activity. Through his eyes, we glimpse the nature of evolution and extinction, and in so doing come to understand the monumental diversity of our planet, and the importance of preserving its wild landscapes, animals, and plants. We also meet some fascinating human characters. By the book's end we are wiser, and more deeply concerned, but Quammen leaves us with a message of excitement and hope.