What at first seemed like a case of food poisoning quickly turned critical, and by the time Tom had been transferred via emergency medevac to the world-class medical center at UC San Diego, where both he and Steffanie worked, blood work revealed why modern medicine was failing: Tom was fighting one of the most dangerous, antibiotic-resistant bacteria in the world.Frantic, Steffanie combed through research old and new and came across phage therapy: the idea that the right virus, aka "the perfect predator," can kill even the most lethal bacteria. Phage treatment had fallen out of favor almost 100 years ago, after antibiotic use went mainstream. Now, with time running out, Steffanie appealed to phage researchers all over the world for help. She found allies at the FDA, researchers from Texas A&M, and a clandestine Navy biomedical center -- and together they resurrected a forgotten cure.

    Debbie St. Germain’s death in her remote trailer, apparently at the hands of her fifth husband, is a passing curiosity. “A real-life old West murder mystery,” the local TV announcers intone before the commercial break, while barroom gossips snicker cruelly. But for her twenty-year-old son, Justin St. Germain, the tragedy marks the line that separates his world into before and after.   Long after his mother’s death is “solved,” closure still seems missing. Distancing himself from the legendary town of his childhood, Justin makes another life a world away in San Francisco and achieves all the surface successes that would have filled his mother with pride. Yet years later he’s still sleeping with a loaded rifle under his bed. Ultimately, he is pulled back to the desert landscape of his childhood on a search to make sense of the unfathomable. What made his mother, a onetime army paratrooper, the type of woman who would stand up to any man except the men she was in love with? What led her to move from place to place, house to house, man to man, job to job, until finally she found herself in a desperate and deteriorating situation, living on an isolated patch of desert with an unstable ex-cop?   Justin’s journey takes him back to the ghost town of Wyatt Earp and the Gunfight at the O.K. Corral, to the trailers he and Debbie shared, to the string of stepfathers who were a constant, sometimes threatening presence in his life, to a harsh world on the margins full of men and women all struggling to define what family means. He decides to confront people from his past and delve into the police records in an attempt to make sense of his mother’s life and death. All the while he tries to be the type of man she would have wanted him to be.   Brutally honest and beautifully written, Son of a Gun is a brave, unexpected and unforgettable memoir.

    Now, for the first time, this EGOT (Emmy, Grammy, Oscar, Tony) winner shares his story in his own words. “I hope fans of comedy will get a kick out of the stories behind my work, and really enjoy taking this remarkable ride with me.”—Mel Brooks For anyone who loves American comedy, the long wait is over. Here are the never-before-told, behind-the-scenes anecdotes and remembrances from a master storyteller, filmmaker, and creator of all things funny.All About Me! charts Mel Brooks’s meteoric rise from a Depression-era kid in Brooklyn to the recipient of the National Medal of Arts. Whether serving in the United States Army in World War II, or during his burgeoning career as a teenage comedian in the Catskills, Mel was always mining his experiences for material, always looking for the perfect joke. His iconic career began with Sid Caesar’s Your Show of Shows, where he was part of the greatest writers’ room in history, which included Carl Reiner, Neil Simon, and Larry Gelbart. After co-creating both the mega-hit 2000 Year Old Man comedy albums and the classic television series Get Smart, Brooks’s stellar film career took off. He would go on to write, direct, and star in The Producers, The Twelve Chairs, Blazing Saddles, Young Frankenstein, Silent Movie, High Anxiety, and Spaceballs, as well as produce groundbreaking and eclectic films, including The Elephant Man, The Fly, and My Favorite Year. Brooks then went on to conquer Broadway with his record-breaking, Tony-winning musical, The Producers. All About Me! offers fans insight into the inspiration behind the ideas for his outstanding collection of boundary-breaking work, and offers details about the many close friendships and collaborations Brooks had, including those with Sid Caesar, Carl Reiner, Gene Wilder, Madeleine Kahn, Alfred Hitchcock, and the great love of his life, Anne Bancroft. Filled with tales of struggle, achievement, and camaraderie (and dozens of photographs), readers will gain a more personal and deeper understanding of the incredible body of work behind one of the most accomplished and beloved entertainers in history.

    She volunteered to take the message to China, where the preaching she did was illegal and could result in her expulsion or worse. Here, she had some distance from her community for the first time. Immersion in a foreign language and culture--and a whole new way of thinking--turned her world upside down, and eventually led her to lose all that she had been sure was true.As a proselytizer in Shanghai, using fake names and secret codes to evade the authorities' notice, Scorah discreetly looked for targets in public parks and stores. To support herself, she found work at a Chinese language learning podcast, hiding her real purpose from her coworkers. Now with a creative outlet, getting to know worldly people for the first time, she began to understand that there were other ways of seeing the world and living a fulfilling life. When one of these relationships became an "escape hatch," Scorah's loss of faith culminated in her own personal apocalypse, the only kind of ending possible for a Jehovah's Witness.Shunned by family and friends as an apostate, Scorah was alone in Shanghai and thrown into a world she had only known from the periphery--with no education or support system. A coming of age story of a woman already in her thirties, this unforgettable memoir examines what it's like to start one's life over again with an entirely new identity. It follows Scorah to New York City, where a personal tragedy forces her to look for new ways to find meaning in the absence of religion. With compelling, spare prose, Leaving the Witness traces the bittersweet process of starting over, when everything one's life was built around is gone.

    Two months later, Max's body would be found in the lake. There’d been no note or obvious indication that Max wanted to harm himself; he’d signed up for a year-long subscription to a dating service; he’d spent the day he disappeared doing photography work for school. And this uncertainty became part of his father’s grief. I Keep Trying to Catch His Eye explores with grace, depth, and refinement the tragically transformative reality of losing a child. But it also tells the deeply human and deeply empathetic story of a father’s relationship with his son, of its complications, and of Max and Ivan’s struggle—as is the case for so many parents and their children—to connect.I Keep Trying to Catch His Eye is a stunning, poignant exploration of the father and son relationship, of how our tendency to overlook men’s mental health can have devastating consequences, and how ultimately letting those who grieve do so openly and freely can lead to greater healing.

    Paul's School recently came under state investigation after extensive reports of sexual abuse on campus, Lacy Crawford thought she'd put behind her the assault she'd suffered at St. Paul's decades before, when she was fifteen. Still, when detectives asked for victims to come forward, she sent a note.Her criminal case file reopened, she saw for the first time evidence that corroborated her memories. Here were depictions of the naïve, hard-working girl she'd been, a chorister and debater, the daughter of a priest; of the two senior athletes who assaulted her and were allowed to graduate with awards; and of the faculty, doctors, and priests who had known about Crawford's assault and gone to great lengths to bury it.Now a wife, mother, and writer living on the other side of the country, Crawford learned that police had uncovered astonishing proof of an institutional silencing years before, and that unnamed powers were still trying to block her case. The slander, innuendo, and lack of adult concern that Crawford had experienced as a student hadn't been imagined as the effects of trauma, after all: these were the actions of a school that prized its reputation above anything, even a child.This revelation launched Crawford on an extraordinary inquiry into the ways gender, privilege, and power shaped her experience as a girl at the gates of America's elite. Her investigation looks beyond the sprawling playing fields and soaring chapel towers of crucibles of power like St. Paul's, whose reckoning is still to come. And it runs deep into the channels of shame and guilt, witness and silencing, that dictate who can speak and who is heard in American society.An insightful, mature, beautifully written memoir, Notes on a Silencing is an arresting coming-of-age story that wrestles with an essential question for our time: what telling of a survivor's story will finally force a remedy?

    As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his co-discovery of the structure of DNA. She and her collaborators turned ​a curiosity ​of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020.

      We swim in freezing Arctic waters and piranha-infested rivers to test our limits. We swim for pleasure, for exercise, for healing. But humans, unlike other animals that are drawn to water, are not natural-born swimmers. We must be taught. Our evolutionary ancestors learned for survival; now, in the twenty-first century, swimming is one of the most popular activities in the world.Why We Swim is propelled by stories of Olympic champions, a Baghdad swim club that meets in Saddam Hussein’s palace pool, modern-day Japanese samurai swimmers, and even an Icelandic fisherman who improbably survives a wintry six-hour swim after a shipwreck. New York Times contributor Bonnie Tsui, a swimmer herself, dives into the deep, from the San Francisco Bay to the South China Sea, investigating what about water—despite its dangers—seduces us and why we come back to it again and again.

    After his death -- a calamity that claimed her favorite person--she returned to that beloved novel as a way of wrestling with his memory and understanding her own grief.Smyth's story moves between the New England of her childhood and Woolf's Cornish shores and Bloomsbury squares, exploring universal questions about family, loss, and homecoming. Through her inventive, highly personal reading of To the Lighthouse, and her artful adaptation of its groundbreaking structure, Smyth guides us toward a new vision of Woolf's most demanding and rewarding novel--and crafts an elegant reminder of literature's ability to clarify and console.Braiding memoir, literary criticism, and biography, All the Lives We Ever Lived is a wholly original debut: a love letter from a daughter to her father, and from a reader to her most cherished author.

    He dropped out of school and joined a group of Dené, Secwépemc, Gitxsan, Dakelh, Apache, Tohono O’odham, Seri, Purépecha, and Maya runners, all fleeing difficult beginnings. Telling their stories alongside his own, Álvarez writes about a four-month-long journey from Canada to Guatemala that pushed him to his limits. He writes not only of overcoming hunger, thirst, and fear―dangers included stone-throwing motorists and a mountain lion―but also of asserting Indigenous and working-class humanity in a capitalist society where oil extraction, deforestation, and substance abuse wreck communities.Running through mountains, deserts, and cities, and through the Mexican territory his parents left behind, Álvarez forges a new relationship with the land, and with the act of running, carrying with him the knowledge of his parents’ migration, and―against all odds in a society that exploits his body and rejects his spirit―the dream of a liberated future.

    All this changed with a phone call that set a journey of discovery in motion, leading to a series of shocking revelations that forced Stephanie to revise the meaning of almost every aspect of her very compromised childhood.American Daughter is at once the deeply moving memoir of a troubled mother-daughter relationship and a meditation on resilience, transcendence, and redemption. Stephanie's story is unique but its messages are universal, offering insight into what it means to rise above, heal, and forgive.

    You can’t help but fall for Chika. A page-turner that will no doubt become a classic.” --Mary Karr, author of The Liars’ Club and The Art of Memoir From the #1 New York Times bestselling author of Tuesdays With Morrie comes Mitch Albom’s most personal story to date: an intimate and heartwarming memoir about what it means to be a family and the young Haitian orphan whose short life would forever change his heart.  Chika Jeune was born three days before the devastating earthquake that decimated Haiti in 2010. She spent her infancy in a landscape of extreme poverty, and when her mother died giving birth to a baby brother, Chika was brought to The Have Faith Haiti Orphanage that Albom operates in Port Au Prince. With no children of their own, the forty-plus children who live, play, and go to school at the orphanage have become family to Mitch and his wife, Janine. Chika’s arrival makes a quick impression. Brave and self-assured, even as a three-year-old, she delights the other kids and teachers. But at age five, Chika is suddenly diagnosed with something a doctor there says, “No one in Haiti can help you with.” Mitch and Janine bring Chika to Detroit, hopeful that American medical care can soon return her to her homeland. Instead, Chika becomes a permanent part of their household, and their lives, as they embark on a two-year, around-the-world journey to find a cure. As Chika’s boundless optimism and humor teach Mitch the joys of caring for a child, he learns that a relationship built on love, no matter what blows it takes, can never be lost. Told in hindsight, and through illuminating conversations with Chika herself, this is Albom at his most poignant and vulnerable. Finding Chika is a celebration of a girl, her adoptive guardians, and the incredible bond they formed—a devastatingly beautiful portrait of what it means to be a family, regardless of how it is made.

    Their magical interlude ends, full stop, when Heather becomes pregnant - Brian is sure he loves her, only he doesn't want kids. Heather returns to California to deliver their daughter alone, buoyed by family and friends. Mere hours after Gracie's arrival, Heather's bliss is interrupted when a nurse wakes her, "Get dressed, your baby is in trouble." This is not how Heather had imagined new motherhood – alone, heartsick, an unexpectedly solo caretaker of a baby who smelled "like sliced apples and salted pretzels" but might be perilously ill. Brian reappears as Gracie's condition grows dire; together Heather and Brian have to decide what they are willing to risk to ensure their girl sees adulthood. The grace and humor that ripple through Harpham's writing transform the dross of heartbreak and parental fears into a clear-eyed, warm-hearted view of the world. Profoundly moving and subtly written, Happiness radiates in many directions - new, romantic love; gratitude for a beautiful, inscrutable world; deep, abiding friendship; the passion a parent has for a child; and the many unlikely ways to build a family. Ultimately it's a story about love and happiness, in their many crooked configurations.

    You want to know what it takes to rise above your circumstances when all the cards are stacked against you? Ask me.Comedian Patricia Williams, who for years went by her street-name "Rabbit," was born and raised in Atlanta’s most troubled neighborhood at the height of the crack epidemic. One of five children, Pat watched as her alcoholic mother struggled to get by on charity, cons and petty crimes. At seven Pat was taught to roll drunks for money. At 12, she was targeted for sex by a man eight years her senior; by 13 she was pregnant. By 15 Pat was a mother of two. Alone at 16, Pat was determined to make a better life for her children. But with no job skills and an eighth-grade education, her options were limited. She learned quickly that hustling and humor were the only tools she had to survive. Rabbit is an unflinching memoir of cinematic scope and unexpected humor that offers a rare glimpse into the harrowing reality of life on America’s margins, resilience, determination, and the transformative power of love.

    Born two years after her parents' only son died just hours after his birth, Kat Chow became unusually fixated with death. She worried constantly about her parents dying -- especially her mother. One morning, when Kat was nine, her mother, a vivacious and mischievous woman, casually made a morbid joke: When she eventually dies, she said laughing, she'd like to be stuffed and displayed in Kat's future apartment in order to always watch over her.Four years later when her mother dies unexpectedly from cancer, Kat, her two older sisters, and their father are plunged into a debilitating, lonely grief. With a distinct voice that is wry and heartfelt, Kat weaves together what is part ghost story and part excavation of her family's history of loss spanning three generations and their immigration from China and Hong Kong to America and Cuba. This redemptive coming-of-age story uncovers the uncanny parallels in Kat's lineage, including the strength of sisterhood and the complicated duty of looking after parents, even after death.Seeing Ghosts asks what it means to claim and tell your family's story: Is writing an exorcism or is it its own form of preservation? What do we owe to our families in our grief, and how does it shape us? In order to answer these questions and to understand her family's ghosts, Kat unearths their sorrow and challenges the power structures of race, class, and gender. The result is an extraordinary new contribution to the literature of grief and the American family, and a provocative and transformative meditation on who we become under the specter of loss.