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Freaks of Nature: What Anomalies Tell Us about Development and Evolution
Mark S. Blumberg - 2008
Born and raised in a small town, they enjoy a close relationship, though each has her own tastes and personality. But the Hensels also share a body. Their two heads sit side-by-side on a single torso, with two arms and two legs. They have not only survived, but have developed into athletic, graceful young women. And that, writes Mark S. Blumberg, opens an extraordinary window onto human development and evolution.In Freaks of Nature, Blumberg turns a scientist's eye on the oddities of nature, showing how a subject once relegated to the sideshow can help explain some of the deepest complexities of biology. Why, for example, does a two-headed human so resemble a two-headed minnow? What we need to understand, Blumberg argues, is that anomalies are the natural products of development, and it is through developmental mechanisms that evolution works. Freaks of Nature induces a kind of intellectual vertigo as it upends our intuitive understanding of biology. What really is an anomaly? Why is a limbless human a freak, but a limbless reptile-a snake-a successful variation?What we see as deformities, Blumberg writes, are merely alternative paths for development, which challenge both the creature itself and our ability to fit it into our familiar categories. Rather than mere dead-ends, many anomalies prove surprisingly survivable-as in the case of the goat without forelimbs that learned to walk upright. Blumberg explains how such variations occur, and points to the success of the Hensel sisters and the goat as examples of the extraordinary flexibility inherent in individual development.In taking seriously a subject that has often been shunned as discomfiting and embarrassing, Mark Blumberg sheds new light on how individuals-and entire species-develop, survive, and evolve.
The Lost Family: How DNA Testing Is Uncovering Secrets, Reuniting Relatives, and Upending Who We Are
Libby Copeland - 2020
She explores the culture of genealogy buffs, the science of DNA, and the business of companies like Ancestry and 23andMe, all while tracing the story of one woman, her unusual results, and a relentless methodical drive for answers that becomes a thoroughly modern genetic detective story.
The Orphans of Davenport: Eugenics, the Great Depression, and the War over Children's Intelligence
Marilyn Brookwood - 2021
Their IQ scores, added together, totaled just 81. Following prevailing eugenic beliefs of the times, Skeels and his colleague Marie Skodak assumed that the girls had inherited their parents’ low intelligence and were therefore unfit for adoption. The girls were sent to an institution for the “feebleminded” to be cared for by “moron” women. To Skeels and Skodak’s astonishment, under the women’s care, the children’s IQ scores became normal.Now considered one of the most important scientific findings of the twentieth century, the discovery that environment shapes children’s intelligence was also one of the most fiercely contested—and its origin story has never been told. In The Orphans of Davenport, psychologist and esteemed historian Marilyn Brookwood chronicles how a band of young psychologists in 1930s Iowa shattered the nature-versus-nurture debate and overthrew long-accepted racist and classist views of childhood development.Transporting readers to a rural Iowa devastated by dust storms and economic collapse, Brookwood reveals just how profoundly unlikely it was for this breakthrough to come from the Iowa Child Welfare Research Station. Funded by the University of Iowa and the Rockefeller Foundation, and modeled on America’s experimental agricultural stations, the Iowa Station was virtually unknown, a backwater compared to the renowned psychology faculties of Stanford, Harvard, and Princeton. Despite the challenges they faced, the Iowa psychologists replicated increased intelligence in thirteen more “retarded” children.When Skeels published their incredible work, America’s leading psychologists—eugenicists all—attacked and condemned his conclusions. The loudest critic was Lewis M. Terman, who advocated for forced sterilization of low-intelligence women and whose own widely accepted IQ test was threatened by the Iowa research. Terman and his opponents insisted that intelligence was hereditary, and their prestige ensured that the research would be ignored for decades. Remarkably, it was not until the 1960s that a new generation of psychologists accepted environment’s role in intelligence and helped launch the modern field of developmental neuroscience..Drawing on prodigious archival research, Brookwood reclaims the Iowa researchers as intrepid heroes and movingly recounts the stories of the orphans themselves, many of whom later credited the psychologists with giving them the opportunity to forge successful lives. A radiant story of the power and promise of science to better the lives of us all, The Orphans of Davenport unearths an essential history at a moment when race science is dangerously resurgent.
Cell Biology,Genetics, Molecular Biology: Evolution And Ecology
P.S. Verma - 2004
Ecosystem: Structure and Function Biogeochemical Cycles, Aquatic Ecosystems: Freshwater Communities, Estuaries and Marine Communities Terrestrial Ecosystems Pollution Ecology and Human Welfare Wild Life Management Biogeography, Adaptations Indices
The Marks of Cain
Tom Knox - 2010
The map leads David into the heart of the dangerous Basque mountains, where a genetic curse lies buried and a frightening secret about the Western world's past is hidden. Meanwhile, London journalist Simon Quinn may have found his big break. A wealthy, elderly woman has been murdered in the most horrific fashion, and another homicide soon follows. Both victims came from villages in the Basque region, both were interred at a top-secret Nazi camp, both have been silenced for what they know about the experiments conducted on the Basques, the Jews, and a dwindling mystical tribe of pre-Caucasian locals called Cagots. From the North Sea islands to the Arizona desert, from the graveyards of the Basque countryside to the heart of colonial Africa, Martinez's and Quinn's quests intersect to reveal the shocking roots of racial persecution, human violence, and war. The Genesis Secret-already in its fourth hardcover printing and appearing on several bestseller lists-immediately established Tom Knox as a searing, brilliant new voice in commercial fiction. The Marks of Cain dares to raise the bar even higher and promises to be an even greater success.
Eve & Adam
Michael Grant - 2012
But before Evening Spiker’s head clears a strange boy named Solo is rushing her to her mother’s research facility. There, under the best care available, Eve is left alone to heal.Just when Eve thinks she will die—not from her injuries, but from boredom—her mother gives her a special project: Create the perfect boy.Using an amazingly detailed simulation, Eve starts building a boy from the ground up. Eve is creating Adam. And he will be just perfect... won’t he?
The Deeper Genome: Why There Is More to the Human Genome Than Meets the Eye
John Parrington - 2015
But things didn't turn out that way. For a start, we turned out to have far fewer genes than originally thought - just over 20,000, the same sort of number as a fruit fly or worm. What's more, the proportionof DNA consisting of genes coding for proteins was a mere 2%. So, was the rest of the genome accumulated 'junk'?Things have changed since those early heady days of the Human Genome Project. But the emerging picture is if anything far more exciting. In this book, John Parrington explains the key features that are coming to light - some, such as the results of the international ENCODE programme, still much debated and controversial in their scope. He gives an outline of the deeper genome, involving layers of regulatory elements controlling and coordinating the switching on and off of genes; the impact ofits 3D geometry; the discovery of a variety of new RNAs playing critical roles; the epigenetic changes influenced by the environment and life experiences that can make identical twins different and be passed on to the next generation; and the clues coming out of comparisons with the genomes ofNeanderthals as well as that of chimps about the development our species. We are learning more about ourselves, and about the genetic aspects of many diseases. But in its complexity, flexibility, and ability to respond to environmental cues, the human genome is proving to be far more subtle than we ever imagined.
The Veil Series: Books 1-3
Pippa DaCosta - 2015
Beyond The Veil, #1 Devil May Care, #2 Darkest Before Dawn, #3Beyond The Veil Charlie Henderson is living a lie. Her real name is Muse and her attempt at a normal life is about to go up in smoke. When a half-demon assassin walks into her life, leaving a trail of destruction in his wake, Muse must return to the one man she hoped never to see again and ask for help. The Prince of Greed isn’t known for his charity. The price is high, and the cost could tear her apart. Trapped between the malevolent intentions of a Prince of Hell and an assassin with ulterior motives, Muse must embrace the lure of chaos at her core; the demon inside her, in order to survive. Devil May Care Three dead Enforcers in three weeks, their bodies butchered. Muse has seen it before, and when she reads the metal memories in the murder weapon, she sees it all again. Her owner, Damien, is back, and he wants what is rightfully his. Darkest Before Dawn When Akil leaves a nine year old half-blood girl on Muse’s doorstep, it’s not long before the demons come hunting, but this time Muse isn’t the target. The Institute, Muse’s immortal brother, and the Princes of Hell, all want a piece of the little half-blood. What’s so special about Dawn, and why has Akil conveniently disappeared just as Muse needs answers?
Eve of Snows
L. James RiceL. James Rice - 2018
Great for fans of George R.R. Martin’s A Song of Ice and Fire series, R. Scott Bakker’s Prince of Nothing series." - Booklife ReviewsFive hundred years ago the world shattered, banishing the gods from the Sister Continents and stealing the memories of the mortal peoples in an event known as the Great Forgetting. In 17 days the stars will align, and a religious cabal will summon the gods back to the realms of men. In the northern tundra priests search the Steaming Lakes, a place tormented by the Wakened Dead. Deep in the mountains, demonic shadows assail priests at a holy shrine. In the south, the clans know something foul is afoot, and dispatch warriors to seek answers, but instead they find horrors. A young priestess named Eliles stands in the heart of this conspiracy; on her shoulders rest decisions which could prevent a holy war or demonic genocide. Through lies, manipulation, and murder, everyone is on a 17-day march to fulfill or defy prophecy; the world will end or begin anew, come the Eve of Snows.
The King's Grave: The Discovery of Richard III’s Lost Burial Place and the Clues it Holds
Philippa Langley - 2013
Earlier this year, the remains of a man with a curving spine, who possible was killed in battle, were discovered underneath the paving of a parking lot in Leicester, England. Phillipa Langley, head of The Richard III Society, spurred on by the work of the historian Michael Jones, led the team of who uncovered the remains, certain that she had found the bones of the monarch. When DNA verification later confirmed that the skeleton was, indeed, that of King Richard III, the discovery ranks among the great stories of passionate intuition and perseverance against the odds. The news of the discovery of Richard's remains has been widely reported by the British as well as worldwide and was front page news for both the New York Times and The Washington Post. Many believe that now, with King Richard III's skeleton in hand, historians will finally begin to understand what happened to him following the Battle of Bosworth Field (twenty miles or so from Leicester) and, ultimately, to know whether he was the hateful, unscrupulous monarch of Shakespeare's drama or a much more benevolent king interested in the common man. Written in alternating chapters, with Richard's 15th century life told by historian Michael Jones (author of the critically acclaimed Bosworth - 1485) contrasting with the 21st century eyewitness account of the search and discovery of the body by Philippa Langley, The King's Grave will be both an extraordinary portrait of the last Plantagenet monarch and the inspiring story of the archaeological dig that finally brings the real King Richard III into the light of day.
Inside the Cell: The Dark Side of Forensic DNA
Erin E. Murphy - 2015
He was five inches shorter and 65 pounds lighter than the suspect described by the victim, but at trial a lab analyst testified that his DNA was found at the crime scene. His case looked like many others -- arrest, swab, match, conviction. But there was just one problem -- Sutton was innocent. We think of DNA forensics as an infallible science that catches the bad guys and exonerates the innocent. But when the science goes rogue, it can lead to a gross miscarriage of justice. Erin Murphy exposes the dark side of forensic DNA testing: crime labs that receive little oversight and produce inconsistent results; prosecutors who push to test smaller and poorer-quality samples, inviting error and bias; law-enforcement officers who compile massive, unregulated, and racially skewed DNA databases; and industry lobbyists who push policies of "stop and spit." DNA testing is rightly seen as a transformative technological breakthrough, but we should be wary of placing such a powerful weapon in the hands of the same broken criminal justice system that has produced mass incarceration, privileged government interests over personal privacy, and all too often enforced the law in a biased or unjust manner. Inside the Cell exposes the truth about forensic DNA, and shows us what it will take to harness the power of genetic identification in service of accuracy and fairness.
Mutants: On Genetic Variety and the Human Body
Armand Marie Leroi - 2003
This elegant, humane, and engaging book "captures what we know of the development of what makes us human" (Nature).Visit Armand Marie Leroi on the web: http: //armandleroi.com/index.htmlStepping effortlessly from myth to cutting-edge science,
Germs, Genes, & Civilization: How Epidemics Shaped Who We Are Today
David P. Clark - 2004
No one can stop him--but he walks away. A miracle? No...dysentery. Microbes saved the Roman Empire. Nearly a millennium later, the microbes of the Black Death ended the Middle Ages, making possible the Renaissance, western democracy, and the scientific revolution. Soon after, microbes ravaged the Americas, paving the way for their European conquest. Again and again, microbes have shaped our health, our genetics, our history, our culture, our politics, even our religion and ethics. This book reveals much that scientists and cultural historians have learned about the pervasive interconnections between infectious microbes and humans. It also considers what our ongoing fundamental relationship with infectious microbes might mean for the future of the human species. The "good side" of history's worst epidemics The surprising debt we owe to killer diseases Where diseases came from... ...and where they may be going Children of pestilence: disease and civilization From Egypt to Mexico, the Romans to Attila the Hun STDs, sexual behavior, and culture How microbes may shape cultural cycles of puritanism and promiscuity
The Gene: An Intimate History
Siddhartha Mukherjee - 2016
It intersects with Darwin’s theory of evolution, and collides with the horrors of Nazi eugenics in the 1940s. The gene transforms post-war biology. It reorganizes our understanding of sexuality, temperament, choice and free will. This is a story driven by human ingenuity and obsessive minds – from Charles Darwin and Gregor Mendel to Francis Crick, James Watson and Rosalind Franklin, and the thousands of scientists still working to understand the code of codes.This is an epic, moving history of a scientific idea coming to life, by the author of The Emperor of All Maladies. But woven through The Gene, like a red line, is also an intimate history – the story of Mukherjee’s own family and its recurring pattern of mental illness, reminding us that genetics is vitally relevant to everyday lives. These concerns reverberate even more urgently today as we learn to “read” and “write” the human genome – unleashing the potential to change the fates and identities of our children.Majestic in its ambition, and unflinching in its honesty, The Gene gives us a definitive account of the fundamental unit of heredity – and a vision of both humanity’s past and future.
Wildwood Academy
Jacqueline Silvester - 2017
Once there, Nikka quickly falls in love with her bizarre classes, the jaw-dropping scenery and... two very different boys. However, Wildwood Academy has a dark and twisted secret, one that could cost Nikka the one thing she had never imagined she could lose, the one thing that money can’t buy. It is this very thing that Wildwood Academy was created to steal. Nikka can stay and lose everything, or she can risk death and run. ***About the Author*** Jacqueline has had a colourful and dual life thus far; she's lived in a refugee camp in Sweden, a castle in France, a village in Germany, and spent her formative years in between Los Angeles, London and New York. As a result, she speaks four languages. Jacqueline has a Bachelors in English Literature from the University Of Massachusetts, and a Masters in Screenwriting from Royal Holloway, University Of London. After graduating she wrote her first novel and began writing cartoon screenplays. The two years she spent in an arts boarding school in the woods have inspired the particular world described in her debut novel Wunderkids. She lives in London with her husband, her excessive YA collection and a hyper husky named Laika. Wunderkids has been translated into a number of languages and featured in Vogue magazine!