His cybernetics are a decade out of date, he's got a pair of twin sister loan sharks knocking on his door, and his work scouting for a baseball league run by pharmaceutical companies is about to go belly-up. Things couldn't get much worse.Then his childhood best friend-Monsanto Mets slugger J.J. Zunz-is murdered at home plate.Determined to find the killer, Kobo plunges into the dark corners and glittering cloud condos of a world ravaged by climate change and repeat pandemics, and where genetic editing and advanced drugs mean you can have any body you want--as long as you can afford it. But even among the philosophical Neanderthals, zootech weapons, and genetically modified CEOs, there's a curveball he never could have called.

    But all of these plans changed when Ronan was diagnosed at nine months old with Tay-Sachs disease, a rare and always-fatal degenerative disorder.  Ronan was not expected to live beyond the age of three; he would be permanently stalled at a developmental level of six months.  Rapp and her husband were forced to re-evaluate everything they thought they knew about parenting.  They would have to learn to live with their child in the moment; to find happiness in the midst of sorrow; to parent without a future.The Still Point of the Turning World is the story of a mother’s journey through grief and beyond it.  Rapp’s response to her son’s diagnosis was a belief that she needed to “make my world big”—to make sense of her family’s situation through art, literature, philosophy, theology and myth.  Drawing on a broad range of thinkers and writers, from C.S. Lewis to Sylvia Plath, Hegel to Mary Shelley’s Frankenstein, Rapp learns what wisdom there is to be gained from parenting a terminally ill child.  In luminous, exquisitely moving prose she re-examines our most fundamental assumptions about what it means to be a good parent, to be a success, and to live a meaningful life.

    Two scientists explore the potential of a revolutionary genetics technology capable of easily and affordably manipulating DNA in human embryos to prevent specific diseases, addressing key concerns about related ethical and societal repercussions.

    But, despite appearances, these are not dogs—they are foxes. They are the result of the most astonishing experiment in breeding ever undertaken—imagine speeding up thousands of years of evolution into a few decades. In 1959, biologists Dmitri Belyaev and Lyudmila Trut set out to do just that, by starting with a few dozen silver foxes from fox farms in the USSR and attempting to recreate the evolution of wolves into dogs in real time in order to witness the process of domestication. This is the extraordinary, untold story of this remarkable undertaking. Most accounts of the natural evolution of wolves place it over a span of about 15,000 years, but within a decade, Belyaev and Trut’s fox breeding experiments had resulted in puppy-like foxes with floppy ears, piebald spots, and curly tails. Along with these physical changes came genetic and behavioral changes, as well. The foxes were bred using selection criteria for tameness, and with each generation, they became increasingly interested in human companionship. Trut has been there the whole time, and has been the lead scientist on this work since Belyaev’s death in 1985, and with Lee Dugatkin, biologist and science writer, she tells the story of the adventure, science, politics, and love behind it all.  In How to Tame a Fox, Dugatkin and Trut take us inside this path-breaking experiment in the midst of the brutal winters of Siberia to reveal how scientific history is made and continues to be made today. To date, fifty-six generations of foxes have been domesticated, and we continue to learn significant lessons from them about the genetic and behavioral evolution of domesticated animals. How to Tame a Fox offers an incredible tale of scientists at work, while also celebrating the deep attachments that have brought humans and animals together throughout time.

    As part of the healing process, she decided to use DNA research to learn more about herself, her family, and the interconnectedness of society. She went deep in search of her genealogy, having her DNA sequenced and tested, and effectively becoming an experimental subject. Remarkably, she was able to trace the path of her ancestors through recorded history and into prehistory. Through the course of her research, she met dozens of scientists working in genetic research. The narrative travels the length and breadth of Europe, from the Neanderthals of central Germany to the Cro-Magnon in France. Bojs visited the ancient caves, realizing that her direct ancestors must have been living in the area when the cave art was painted. A second DNA analysis later revealed she has Sami (i.e. Lapp) genetic material in her genome, and there were further revelations about her hunter-gatherer, Bronze-Age, and Iron-Age relatives, including the Vikings. This fresh, first-person exploration of genes and genetics goes well beyond personal genealogy and reveals much about the shared history of European peoples.

    Our Inheritance 2. Mendel and Genes 3. Genes and Chromosomes 4. The Search for the GeneDNA 5. DNA Structure and Replication 6. DNA Expression in Proteins 7. Genes, Enzymes, and Metabolism 8. From DNA to Protein 9. Genomes 10. Manipulating GenesRecombinant DNA 11. Isolating Genes and DNA 12. BiotechnologyGenetic Engineering 13. Biotechnology and the Environment 14. Manipulating DNA by PCR and Other Methods 15. DNA in IdentificationForensics 16. DNA and Evolution 17. DNA and Human Evolution 18. Molecular MedicineGenetic Screening 19. Molecular MedicineThe Immune System 20. Molecular MedicineCancer 21. Molecular MedicineGene Therapy 22. Molecular MedicineCloning and Stem Cells 23. Genetics and Agriculture 24. Biotechnology and Agriculture

    Lisa Seachrist Chiu has a smorgasbord of stories to tell about rare and not so rare genetic quirks. We read about the Dracula Gene, a mutation in zebra fish that causes blood cells to explode on contact with light, and suites of genes that also influence behavior and physical characteristics; the Tangier Island Gene, first discovered after physicians discovered a boy with orange tonsils (scientists now realize that the child's odd condition comes from an inability to process cholesterol); and Wilson's Disease, a gene defect that fails to clear copper from the body, which can trigger schizophrenia and other neurological symptoms, and can be fatal if left untreated. Friendlier mutations include the Myostatin gene, which allows muscles to become much larger than usual and enhances strength and the much-envied Cheeseburger Gene, which allows a lucky few to eat virtually anything they want and remain razor thin. While fascinating us with stories of genetic peculiarities, Chiu also manages to effortlessly explain much of the cutting-edge research in modern genetics, resulting in a book that is both informative and entertaining. It is a must read for everyone who loves popular science or is curious about the human body.

    But how did Watson and Crick do it—and why were they the ones who succeeded?In truth, the discovery of DNA’s structure is the story of five towering minds in pursuit of the advancement of science, and for almost all of them, the prospect of fame and immortality: Watson, Crick, Rosalind Franklin, Maurice Wilkins, and Linus Pauling. Each was fascinating and brilliant, with strong personalities that often clashed. Howard Markel skillfully re-creates the intense intellectual journey, and fraught personal relationships, that ultimately led to a spectacular breakthrough. But it is Rosalind Franklin—fiercely determined, relentless, and an outsider at Cambridge and the University of London in the 1950s, as the lone Jewish woman among young male scientists—who becomes a focal point for Markel.The Secret of Life is a story of genius and perseverance, but also a saga of cronyism, misogyny, anti-Semitism, and misconduct. Drawing on voluminous archival research, including interviews with James Watson and with Franklin’s sister, Jenifer Glynn, Markel provides a fascinating look at how science is done, how reputations are undone, and how history is written, and revised.A vibrant evocation of Cambridge in the 1950s, Markel also provides colorful depictions of Watson and Crick—their competitiveness, idiosyncrasies, and youthful immaturity—and compelling portraits of Wilkins, Pauling, and most cogently, Rosalind Franklin. The Secret of Life is a lively and sweeping narrative of this landmark discovery, one that finally gives the woman at the center of this drama her due.

    A dramatic and carefully detailed account of one family's journey through the maze of genetic counseling, medical technology, and disability rights; destined to become required reading for anyone touched by any of these issues.

    In The Compatibility Gene, one of our foremost immunologists tells the remarkable history of these genes' discovery and the unlocking of their secrets. Davis shows how the compatibility gene is radically transforming our knowledge of the way our bodies work - and is having profound consequences for medical research and ethics. Looking to the future, he considers the startling possibilities of what these wondrous discoveries might mean for you and me.

    After spending the first half of his life as an adamant omnivore, Lindstrom went 100% vegan. Reluctantly. Overnight. From burgers to beets, from pork to parsnips.It’s time for a down-to-earth book that proves anyone can go vegan (even someone who once ate sixty-eight chicken wings in a sitting). How can a man adopt a vegan approach? Won’t he die of protein deficiency? What if he is married to a vegan woman? How would he order a salad at a Minnesota steakhouse? What should he bring to a gluten-free, nut-free, macrobiotic, nightshade-free, oil-free, vegan potluck (true story)?The Skeptical Vegan explains how simple it really is to be vegan, covering topics from food and nutrition to social challenges and lifestyle. Snarky, witty, and opinionated to a fault, Lindstrom speaks as a male vegan, contesting the notion that “real men” should only eat meat. With twenty original “veganized” recipes including portobello steaks, carrot hot dogs, tofu wings, “meaty” chili, and cauliflower bites (which helped him shed thirty pounds), Lindstrom demonstrates how to take control of your diet while still eating “meatily” and taking into account the ethical considerations of living a better life for the animals, the environment, and yourself.

    He found a precarious balance as a con man, but when a client offers him untold wealth to move a squadron of warships across an enemy wormhole, he must embrace his birthright to even try. In fact, the job is so big that he'll need a crew built from all the new sub-branches of humanity. If he succeeds, he might trigger an interstellar war, but success might also point the way to the next step of Homo quantus evolution.

    Lieberman illuminates how these ongoing changes have brought many benefits, but also have created novel conditions to which our bodies are not entirely adapted, resulting in a growing incidence of obesity and new but avoidable diseases, including type-2 diabetes. He proposes that many of these chronic illnesses persist and in some cases are intensifying because of "dysevolution," a pernicious dynamic whereby only the symptoms rather than the causes of these maladies are treated. And finally—provocatively—he advocates the use of evolutionary information to help nudge, push, and sometimes oblige us to create a more salubrious environment.(With charts and line drawings throughout.)From the Hardcover edition.

    They are GENs, Genetically Engineered Non-humans, and in their strict caste system, GENs are at the bottom rung of society. GENs are gestated in a tank and sent to work as slaves as soon as they reach age fifteen.When Kayla is Assigned to care for Zul Manel, the patriarch of a trueborn family, she finds secrets and surprises; not least of which is her unexpected friendship with Zul's great-grandson. Meanwhile, the children that Mishalla is Assigned to care for are being stolen in the middle of the night. After weeks of toiling in their Assignments, mystifying circumstances enable Kayla and Mishalla to reunite. Together they hatch a plan to save the disappearing children. Yet can GENs really trust humans? Both girls must put their lives and hearts at risk to crack open a sinister conspiracy, revealing secrets no one is ready to face.

    Realizing that the child has no living relatives, Jenny begins to care for Lucy as her own. But as she reads the late scientist’s notebooks, she discovers that Lucy is the result of a shocking experiment, and that the adorable, magical, wonderful girl she has come to love is an entirely new hybrid species—half human, half bonobo.