When an epidemic hits, the EIS will be there to crack the case, however mysterious or deadly, saving countless lives in the process. Over the years they have successfully battled polio, cholera, and smallpox, to name a few, and in recent years have turned to the epidemics killing us now--smoking, obesity, and gun violence among them.The successful EIS model has spread internationally: former EIS officers on the staff of the Centers for Disease Control have helped to establish nearly thirty similar programs around the world. EIS veterans have gone on to become leaders in the world of public health in organizations such as the World Health Organization."Inside the Outbreaks" takes readers on a riveting journey through the history of this remarkable organization, following Epidemic Intelligence Service officers on their globetrotting quest to eliminate the most lethal and widespread threats to the world's health.

    We are most familiar with the viruses that give us colds or the flu, but viruses also cause a vast range of other diseases, including one disorder that makes people sprout branch-like growths as if they were trees. Viruses have been a part of our lives for so long, in fact, that we are actually part virus: the human genome contains more DNA from viruses than our own genes. Meanwhile, scientists are discovering viruses everywhere they look: in the soil, in the ocean, even in caves miles underground.This fascinating book explores the hidden world of viruses—a world that we all inhabit. Here Carl Zimmer, popular science writer and author of Discover magazine’s award-winning blog The Loom, presents the latest research on how viruses hold sway over our lives and our biosphere, how viruses helped give rise to the first life-forms, how viruses are producing new diseases, how we can harness viruses for our own ends, and how viruses will continue to control our fate for years to come. In this eye-opening tour of the frontiers of biology, where scientists are expanding our understanding of life as we know it, we learn that some treatments for the common cold do more harm than good; that the world’s oceans are home to an astonishing number of viruses; and that the evolution of HIV is now in overdrive, spawning more mutated strains than we care to imagine.The New York Times Book Review calls Carl Zimmer “as fine a science essayist as we have.” A Planet of Viruses is sure to please his many fans and further enhance his reputation as one of America’s most respected and admired science journalists.

    Generations have been told Burr was a betrayer of Hamilton, of his country, of those who had nobler ideas. All untrue. He did not turn on Hamilton; rather, the politically aggressive Hamilton was preoccupied with Burr and subverted Burr's career at every turn for more than a decade through outright lies and slanderous letters. In Fallen Founder, Nancy Isenberg portrays the founders as they all really were and proves that Burr was no less a patriot and no less a principled thinker than those who debased him. He was an inspired politician who promoted decency at a moment when factionalism and ugly party politics were coalescing. He was a genuine hero of the Revolution, as much an Enlightenment figure as Jefferson, and a feminist generations ahead of his time. A brilliant orator and lawyer, he was New York's attorney general, a senator, and vice president. Denounced as a man of extreme tastes, he in fact pursued a moderate course, and his political assassination was accomplished by rivals who feared his power and who promoted the notion of his sexual perversions. Fallen Founder is an antidote to the worshipful biographies far too prevalent in the histories of the revolutionary era. Burr's story returns us to reality: to the cunning politicians our nation's founders really were and to a world of political maneuvering, cutthroat politicking, and media slander that is stunningly modern.

    From the battles at Lexington and Concord in spring 1775 to those at Trenton and Princeton in winter 1777, American militiamen and then the ragged Continental Army take on the world’s most formidable fighting force. It is a saga alive with astonishing characters: Henry Knox, the former bookseller with an uncanny understanding of artillery; Nathanael Greene, the bumpkin who becomes a brilliant battle captain; Benjamin Franklin, who proves to be the wiliest of diplomats; George Washington, the commander in chief who learns the difficult art of leadership when the war seems all but lost. The story is also told from the British perspective, making the mortal conflict between the redcoats and the rebels all the more compelling.

    General George Washington found his troops outmanned and outmaneuvered at the Battle of Brooklyn, and it looked like there was no escape. But thanks to a series of desperate rear guard attacks by a single heroic regiment, famously known as the “Immortal 400,” Washington was able to evacuate his men and the nascent Continental Army lived to fight another day.Today, only a modest, rusted and scarred metal sign near a dilapidated auto garage marks the mass grave where the bodies of the “Maryland Heroes” lie—256 men “who fell in the Battle of Brooklyn.” In Washington’s Immortals, best-selling military historian Patrick K. O’Donnell brings to life the forgotten story of this remarkable band of brothers. Known as “gentlemen of honour, family, and fortune,” they fought not just in Brooklyn, but in key battles including Trenton, Princeton, Camden, Cowpens, Guilford Courthouse, and Yorktown, where their heroism changed the course of the war.Drawing on extensive original sources, from letters to diaries to pension applications, O’Donnell pieces together the stories of these brave men—their friendships, loves, defeats, and triumphs. He explores their arms and tactics, their struggles with hostile loyalists and shortages of clothing and food, their development into an elite unit, and their dogged opponents, including British General Lord Cornwallis. And through the prism of this one group, O’Donnell tells the larger story of the Revolutionary War. Washington’s Immortals is gripping and inspiring boots-on-the-ground history, sure to appeal to a wide readership.

     A riveting, powerful telling of the story of the grassroots movement of activists, many of them in a life-or-death struggle, who seized upon scientific research to help develop the drugs that turned HIV from a mostly fatal infection to a manageable disease. Ignored by public officials, religious leaders, and the nation at large, and confronted with shame and hatred, this small group of men and women chose to fight for their right to live by educating themselves and demanding to become full partners in the race for effective treatments. Around the globe, 16 million people are alive today thanks to their efforts. Not since the publication of Randy Shilts's classic And the Band Played On has a book measured the AIDS plague in such brutally human, intimate, and soaring terms. In dramatic fashion, we witness the founding of ACT UP and TAG (Treatment Action Group), and the rise of an underground drug market in opposition to the prohibitively expensive (and sometimes toxic) AZT. We watch as these activists learn to become their own researchers, lobbyists, drug smugglers, and clinicians, establishing their own newspapers, research journals, and laboratories, and as they go on to force reform in the nation s disease-fighting agencies. With his unparalleled access to this community David France illuminates the lives of extraordinary characters, including the closeted Wall Street trader-turned-activist, the high school dropout who found purpose battling pharmaceutical giants in New York, the South African physician who helped establish the first officially recognized buyers club at the height of the epidemic, and the public relations executive fighting to save his own life for the sake of his young daughter. Expansive yet richly detailed, this is an insider's account of a pivotal moment in the history of American civil rights. Powerful, heart-wrenching, and finally exhilarating, How to Survive a Plague is destined to become an essential part of the literature of AIDS.

    In June 1962, a young biologist in Philadelphia, using tissue extracted from an aborted fetus from Sweden, produced safe, clean cells that allowed the creation of vaccines against rubella and other common childhood diseases. Two years later, in the midst of a devastating German measles epidemic, his colleague developed the vaccine that would one day wipe out homegrown rubella. The rubella vaccine and others made with those fetal cells have protected more than 150 million people in the United States, the vast majority of them preschoolers. The new cells and the method of making them also led to vaccines that have protected billions of people around the world from polio, rabies, chicken pox, measles, hepatitis A, shingles and adenovirus. Meredith Wadman’s masterful account recovers not only the science of this urgent race, but also the political roadblocks that nearly stopped the scientists. She describes the terrible dilemmas of pregnant women exposed to German measles and recounts testing on infants, prisoners, orphans, and the intellectually disabled, which was common in the era. These events take place at the dawn of the battle over using human fetal tissue in research, during the arrival of big commerce in campus labs, and as huge changes take place in the laws and practices governing who “owns” research cells and the profits made from biological inventions. It is also the story of yet one more unrecognized woman whose cells have been used to save countless lives. With another frightening virus imperiling pregnant women on the rise today, no medical story could have more human drama, impact, or urgency today than The Vaccine Race.

    Chartered by Queen Elizabeth I, their colony was to establish a foothold for England in the New World. But by the time the colony's leader, John White, returned to Roanoke from a resupply mission in England, his settlers were nowhere to be found. They had vanished into the wilderness, leaving behind only a single clue--the word "Croatoan" carved into a tree. The disappearance of the Lost Colony became an enduring American mystery. For four centuries, it has gone unsolved, obsessing countless historians, archeologists, and amateur sleuths. Today, after centuries of searching in vain, new clues have begun to surface. In The Secret Token, Andrew Lawler offers a beguiling history of the Lost Colony, and of the relentless quest to bring its fate to light. He accompanies competing archeologists as they seek out evidence, each team hoping to be the first to solve the riddle. In the course of his journey, Lawler explores how the Lost Colony came to haunt our national consciousness, working its way into literature, popular culture, and politics. Incisive and absorbing, The Secret Token offers a new understanding not just of the Lost Colony, but of how its absence continues to define--and divide--America.

    history. But few Americans know the true story of the men and women who launched a desperate strike at the slaveholding South. Now, Midnight Rising portrays Brown's uprising in vivid color, revealing a country on the brink of explosive conflict.Brown, the descendant of New England Puritans, saw slavery as a sin against America's founding principles. Unlike most abolitionists, he was willing to take up arms, and in 1859 he prepared for battle at a hideout in Maryland, joined by his teenage daughter, three of his sons, and a guerrilla band that included former slaves and a dashing spy. On October 17, the raiders seized Harpers Ferry, stunning the nation and prompting a counterattack led by Robert E. Lee. After Brown's capture, his defiant eloquence galvanized the North and appalled the South, which considered Brown a terrorist. The raid also helped elect Abraham Lincoln, who later began to fulfill Brown's dream with the Emancipation Proclamation, a measure he called "a John Brown raid, on a gigantic scale."Tony Horwitz's riveting book travels antebellum America to deliver both a taut historical drama and a telling portrait of a nation divided—a time that still resonates in ours.

    Intriguingly fascinating and entertaining reading for anyone who is interested in how society copes with catastrophe and pain. Relevant today in face of the worldwide medical calamity of AIDS. Continuously in print since its first publication in 1934, with over 75 printings.

    When first published in 1969, this study was described by the Guardian as …as exciting and readable an account as you could wish." This new edition of the major study on the subject is illustrated by over seventy contemporary black and white illustrations and eight pages of color.A series of natural disasters in the furthest reaches of the Orient during the third of the fourteenth century heralded what was, for the population of Europe, the most devastating period of death and destruction in its history. By the autumn of 1347 the Black Death had reached the shores of the eastern Mediterranean, and the years that followed were to witness a horrifying and apparently relentless epidemic.One third of England's population died between the years 1347 and 1350, and over one thousand villages were deserted, never to be repopulated. In towns and cities the cemeteries were unable to provide space for all the dead, and violence and crime spiraled. Travel became dangerous and interruption of food and other supplies across the country added hunger and deprivation to the problems of people already overwhelmed by the threat of the vilest of deaths. In the countryside the population was halved in places, and as land became plentiful, landowners' profits fell and the government tried in vain to fix labourers' wages and prices, peasant unrest accelerated and the manorial system disintegrated, culminating eventually in the Peasants' Revolt of 1381. Throughout Europe whole societies were disrupted; racial tensions built as a direct result of the plague, and persecution of Jews began in earnest throughout the continent. The social and economic consequences of the period were to reach far into the following century.

    As Ferling demonstrates, it was a war that America came much closer to losing than is now usually remembered. General George Washington put it best when he said that the American victory was "little short of a standing miracle." Almost a Miracle offers an illuminating portrait of America's triumph, offering vivid descriptions of all the major engagements, from the first shots fired on Lexington Green to the surrender of General Cornwallis at Yorktown, revealing how these battles often hinged on intangibles such as leadership under fire, heroism, good fortune, blunders, tenacity, and surprise. Ferling paints sharp-eyed portraits of the key figures in the war, including General Washington and other American officers and civilian leaders. Some do not always measure up to their iconic reputations, including Washington himself. The book also examines the many faceless men who soldiered, often for years on end, braving untold dangers and enduring abounding miseries. The author explains why they served and sacrificed, and sees them as the forgotten heroes who won American independence.

    No one can stop him--but he walks away. A miracle? No...dysentery. Microbes saved the Roman Empire. Nearly a millennium later, the microbes of the Black Death ended the Middle Ages, making possible the Renaissance, western democracy, and the scientific revolution. Soon after, microbes ravaged the Americas, paving the way for their European conquest. Again and again, microbes have shaped our health, our genetics, our history, our culture, our politics, even our religion and ethics. This book reveals much that scientists and cultural historians have learned about the pervasive interconnections between infectious microbes and humans. It also considers what our ongoing fundamental relationship with infectious microbes might mean for the future of the human species. The "good side" of history's worst epidemics The surprising debt we owe to killer diseases Where diseases came from... ...and where they may be going Children of pestilence: disease and civilization From Egypt to Mexico, the Romans to Attila the Hun STDs, sexual behavior, and culture How microbes may shape cultural cycles of puritanism and promiscuity

    In setting up his household he took Tobias Lear, his celebrated secretary, and nine slaves, including Ona Judge, about which little has been written. As he grew accustomed to Northern ways, there was one change he couldn’t get his arms around: Pennsylvania law required enslaved people be set free after six months of residency in the state. Rather than comply, Washington decided to circumvent the law. Every six months he sent the slaves back down south just as the clock was about to expire.Though Ona Judge lived a life of relative comfort, the few pleasantries she was afforded were nothing compared to freedom, a glimpse of which she encountered first-hand in Philadelphia. So, when the opportunity presented itself one clear and pleasant spring day in Philadelphia, Judge left everything she knew to escape to New England. Yet freedom would not come without its costs.At just twenty-two-years-old, Ona became the subject of an intense manhunt led by George Washington, who used his political and personal contacts to recapture his property.Impeccably researched, historian Erica Armstrong Dunbar weaves a powerful tale and offers fascinating new scholarship on how one young woman risked it all to gain freedom from the famous founding father.

    From the fourteenth-century plague to HIV/AIDS today, diseases have fundamentally altered the shape of society, politics, and culture. In a sweeping, thoughtful account, "Twelve Diseases That Changed Our World" considers the history of twelve important diseases: their impact, their consequences, their costs, and the lessons learned. Examining hemophilia, blight, tuberculosis, cholera, smallpox, bubonic plague, influenza, malaria, yellow fever, and syphilis, this book not only covers the diseases' histories but also addresses public health responses and societal upheavals. Historical perspectives on these diseases will be indispensable for a better understanding of how we and our forbearers survived the onslaught of "plagues" and how we might avoid their devastating consequences in the future. Crucial to this examination is exploring how past experience can help us to deal effectively with "coming plagues." Whether attempts to control outbreaks were successful or not, lessons can be learned that are crucial for disease containment today. Most significantly, this book explains the lessons learned from attempts to contain past disease outbreaks and how that knowledge can be utilized in the future. Despite the challenges that a major epidemic presents, "Twelve Diseases That Changed Our World" also details various past successes in which diseases were brought under control and social disorder was minimized.