Within a few short decades the most hostile of the world’s environments had all been conquered. Likewise, in the twentieth century, medicine transformed human life. Doctors took what was routinely fatal and made it survivable. As modernity brought us ever more into different kinds of extremis, doctors pushed the bounds of medical advances and human endurance. Extreme exploration challenged the body in ways that only the vanguard of science could answer. Doctors, scientists, and explorers all share a defining trait: they push on in the face of grim odds. Because of their extreme exploration we not only understand our physiology better; we have also made enormous strides in the science of healing.Drawing on his own experience as an anesthesiologist, intensive care expert, and NASA adviser, Dr. Kevin Fong examines how cuttingedge medicine pushes the envelope of human survival by studying the human body’s response when tested by physical extremes. Extreme Medicine explores different limits of endurance and the lens each offers on one of the systems of the body. The challenges of Arctic exploration created opportunities for breakthroughs in open heart surgery; battlefield doctors pioneered techniques for skin grafts, heart surgery, and trauma care; underwater and outer space exploration have revolutionized our understanding of breathing, gravity, and much more. Avant-garde medicine is fundamentally changing our ideas about the nature of life and death.Through astonishing accounts of extraordinary events and pioneering medicine, Fong illustrates the sheer audacity of medical practice at extreme limits, where human life is balanced on a knife’s edge. Extreme Medicine is a gripping debut about the science of healing, but also about exploration in its broadest sense—and about how, by probing the very limits of our biology, we may ultimately return with a better appreciation of how our bodies work, of what life is, and what it means to be human.

    In July 1518 a terrifying and mysterious plague struck the medieval city of Strasbourg. Hundreds of men and women danced wildly, day after day, in the punishing summer heat. They did not want to dance, but could not stop. Throughout August and early September more and more were seized by the same terrible compulsion. By the time the epidemic subsided, heat and exhaustion had claimed an untold number of lives, leaving thousands bewildered and bereaved, and an enduring enigma for future generations. Drawing on fresh evidence, John Waller's account of the bizarre events of 1518 explains why Strasbourg's dancing plague took place. In doing so it leads us into a largely vanished world, evoking the sights, sounds, aromas, diseases and hardships, the fervent supernaturalism, and the desperate hedonism of the late medieval world. At the same time, the extraordinary story this book tells offers rich insights into how people behave when driven beyond the limits of endurance. Above all, this is an exploration into the strangest capabilities of the human mind and the extremes to which fear and irrationality can lead us.

    It’s what I won a Pulitzer Prize for, years ago. I go to epidemics, wars, places where people are struggling to cope with disasters, and I carefully log the accounts and events, trying to represent the lives and experiences of others. The position of “outsider” is emotionally safe, even as agonizing events unfold. But I could not distance myself from the extraordinary sequence of events that fell on America, and especially my home town of New York City, in 2001. A decade later I am still trying to understand how the attacks on the World Trade Center and the anthrax mailings affected me, and those I love. I heard the first jet slam into the north tower of the World Trade Center, and from the rooftop of my apartment building watched the second commercial jet veer towards lower Manhattan, change its trajectory, and slice across the upper floors of the south tower. I was standing on the Manhattan anchorage of the Brooklyn Bridge when the first tower crumbled like a deflated accordion, spewing dust and debris in every direction and crushing the life out of thousands of people within. And a month later, as people started falling ill from inhalation of anthrax spores, one of the nation’s top bioterrorism experts called me to warn that I was a likely target: Stop opening your mail. The flow of these events, from the hijacking of four commercial jets on September 11th to the November death of an anthrax-infected Connecticut villager, took most of the world population from a remarkably united emotional and political place, to a deeply divided, frustrated, angry position. The arc of the response matters: It ultimately determined the course of historic events worldwide and tore America asunder, the people having lost trust in their government and without it, most forms of social cohesion. By the end of the winter of 2002 the arc had completed, from spectacular unity and confidence in governance to deep division and accusations of American arrogance. Through the frustrated anthrax investigations and drumbeats of war, the global community, especially Americans, moved in just a few months’ time from collectivism to fragmentation.This book is structured in two parts. The first, THE END OF THE AGE OF INNOCENCE, is written in the present tense, describing almost hourly the events that unfolded primarily in Washington DC and New York City over 120 days in the fall and winter of 2001 and 2002. Each day is a chapter that opens with the actual diary entry that I sent on that date to a list of friends all over the world. The entry is followed by a detailed breakdown of the day’s events, unfolding like a novel.Part two, NEW WORLD ORDER, details the repercussions of these events, transformations of critical government institutions, public health disasters, and what, in particular, the specter of terrorism meant for the American people. Revelations abound in this book, including:• The bizarre chemistry of The Plume that rose from the burning crushed World Trade Center for four months, endangering the health of hundreds of thousands of New Yorkers.• Evidence that al-Qaeda may have been behind the anthrax mailings.• Devastating spending and restructuring followed the attacks, leaving the nation less prepared for terrorism ten years later, and broke.• Each incident following the opening of anthrax-laden letters reveals countless errors and misjudgments.• There was no “weapons-grade anthrax” in those letters – a finding with profound health and political implications.

    While detailing the history of vaccine invention, Kinch reveals the ominous reality that our victories against vaccine-preventable diseases are not permanent—and could easily be undone. In the tradition of John Barry’s The Great Influenza and Siddhartha Mukherjee’s The Emperor of All Maladies, Between Hope and Fear relates the remarkable intersection of science, technology and disease that has helped eradicate many of the deadliest plagues known to man.

    It accommodates four of our five senses, encases the brain, and boasts the most expressive set of muscles in the body. It is our most distinctive attribute and connects our inner selves to the outer world. Yet there is a dark side to the head’s preeminence, one that has, in the course of human history, manifested itself in everything from decapitation to headhunting. So explains anthropologist Frances Larson in this fascinating history of decapitated human heads. From the Western collectors whose demand for shrunken heads spurred massacres to Second World War soldiers who sent the remains of the Japanese home to their girlfriends, from Madame Tussaud modeling the guillotined head of Robespierre to Damien Hirst photographing decapitated heads in city morgues,from grave-robbing phrenologists to skull-obsessed scientists, Larson explores our macabre fixation with severed heads.

    It is our knowledge of their secret lives, the eons spent quietly passing in and out of myriad other life forms, mutating and coadapting, that gives us hope of taming them. By putting these organisms—from bubonic plague to Ebola—at center-stage, Wills shows how we will eventually master them.

    Yet under the right circumstances, it is the single most dangerous germ on the planet.Orent reveals how Soviet scientists created genetically-altered forms of this terrible affliction, knowing exactly how to convert plague into a deadly weapon.She shows how scientists are still unable to defend against it, and how plague could be visited upon humanity again.

    Elizabeth A. Fenn is the first historian to reveal how deeply variola affected the outcome of the war in every colony and the lives of everyone in North America.By 1776, when military action and political ferment increased the movement of people and microbes, the epidemic worsened. Fenn's remarkable research shows us how smallpox devastated the American troops at Québec and kept them at bay during the British occupation of Boston. Soon the disease affected the war in Virginia, where it ravaged slaves who had escaped to join the British forces. During the terrible winter at Valley Forge, General Washington had to decide if and when to attempt the risky inoculation of his troops. In 1779, while Creeks and Cherokees were dying in Georgia, smallpox broke out in Mexico City, whence it followed travelers going north, striking Santa Fe and outlying pueblos in January 1781. Simultaneously it moved up the Pacific coast and east across the plains as far as Hudson's Bay.The destructive, desolating power of smallpox made for a cascade of public-health crises and heartbreaking human drama. Fenn's innovative work shows how this mega-tragedy was met and what its consequences were for America.

    How many of us understand the way seizures affect the brain, how the heart is connected to wellbeing, or the why the foot carries the key to our humanity? In Adventures in Human Being, award-winning author Gavin Francis leads readers on a journey into the hidden pathways of the human body, offering a guide to its inner workings and a celebration of its marvels.Drawing on his experiences as a surgeon, ER specialist, and family physician, Francis blends stories from the clinic with episodes from medical history, philosophy, and literature to describe the body in sickness and in health, in living and in dying. At its heart, Adventures in Human Being is a meditation on what it means to be human. Poetic, eloquent, and profoundly perceptive, this book will transform the way you view your body.

    David Abulafia's The Great Sea is the first complete history of the Mediterranean, from the erection of temples on Malta around 3500 BC to modern tourism. Ranging across time and the whole extraordinary space of the Mediterranean from Gibraltar to Jaffa, Genoa to Tunis, and bringing to life pilgrims, pirates, sultans and naval commanders, this is the story of the sea that has shaped much of world history.

    A killer with little respect for class or wealth, cholera ravaged the squalid streets of Soho and rocked the great centers of Victorian power. In this gripping book, Sandra Hempel tells the story of John Snow, a reclusive doctor without money or social position, who—alone and unrecognized—had the genius to look beyond the conventional wisdom of his day and uncover the truth behind the pandemic. She describes how Snow discovered that cholera was spread through drinking water and how this subsequently laid the foundations for the modern, scientific investigation of today's fatal plagues. A dramatic account with a colorful cast of characters, The Strange Case of the Broad Street Pump features diversions into fascinating facets of medical and social history, such as Snow's tending of Queen Victoria in childbirth, Dutch microbiologist Leeuwenhoek's deliberate breeding of lice in his socks, Dickensian children's farms, and riotous nineteenth-century anesthesia parties. An afterword discusses the new threat of infectious diseases—including malaria, yellow fever, and cholera—with today's global warming. Copub: Granta

    In this book, he builds on that theme by showing why this is the luckiest time yet to be alive, giving you the keys to the new kingdom of wellness.Medicine is undergoing rapid change. In the old world, you followed general principles and doctors treated you based on broad, one-size-fits all solutions. In this new golden age, you’ll be able to take full advantage of the latest scientific findings and leverage the power of technology to customize your care. Only those who know how to access and adapt to these breakthroughs—without being distracted by hyped ideas and bad medicine—will benefit. Imagine being able to get fit and lose weight without dieting, train your immune system to fight cancer, edit your DNA to avoid a certain fate, erase the risk of a heart attack, reverse aging, and know exactly which drugs to take to optimize health with zero side effects.That’s the picture of the future that you can enter starting today. Welcome to The Lucky Years.

    Doctors and scientists at prestigious institutions were pressured to produce medical advances to compete with the perceived threats coming from the Soviet Union. In Against Their Will, authors Allen Hornblum, Judith Newman, and Gregory Dober reveal the little-known history of unethical and dangerous medical experimentation on children in the United States. Through rare interviews and the personal correspondence of renowned medical investigators, they document how children—both normal and those termed "feebleminded"—from infants to teenagers, became human research subjects in terrifying experiments. They were drafted as "volunteers" to test vaccines, doused with ringworm, subjected to electric shock, and given lobotomies. They were also fed radioactive isotopes and exposed to chemical warfare agents. This groundbreaking book shows how institutional superintendents influenced by eugenics often turned these children over to scientific researchers without a second thought. Based on years of archival work and numerous interviews with both scientific researchers and former test subjects, this is a fascinating and disturbing look at the dark underbelly of American medical history.

    You will be astonished to learn about some of the events that have occurred! Here is a Sneak Peek of What you will Learn: - Ancient History - Asian History - European and Russian History - American History - Australian History - World Wars I & II, and the Vietnam War - And much, much, more Here is what other readers say about this book: "This book is packed with really important information about the world's history." "I was surprised how much I learned from this. I really like how everything is laid out, it makes it very easy to follow. I especially like the section on Native Americans" "I couldn't put this book down, and not because I'm a nerdy avid reader (I am) but because it's filled with so much about our world history without the facts jumping all over the place like some history books I've read." "I am highly impressed by the content of this book and I would recommend this to all my colleagues as well" Subjects include: Ancient Greece, Ancient Egypt, The Roman Empire, Constantine and Christianity, India, Ancient Korea, Chinese Dynasties, Napoleonic Europe, Foundation of USA, The 1812 War, Australia and Wars, World War I, World War II, The Ottoman Empire, Greece and North Africa, The Diem Regime, Pearl Harbor and much more! All Continents As Known Today Are Covered: North America, Europe, Asia, Africa and Australia. Take action and get this book now!

    While apocalyptic weather patterns destroyed entire harvests and incited mass migrations, they gave rise to the growth of European cities, the emergence of early capitalism, and the vigorous stirrings of the Enlightenment. A timely examination of how a society responds to profound and unexpected change, Nature’s Mutiny will transform the way we think about climate change in the twenty-first century and beyond.