With the assistance of a co-author, this popular student textbook has now been updated to include techniques such as membrane chromatography, aqueous phase partitioning, engineering recombinant proteins for purification and due to the rapid advances in bioinformatics/proteomics a discussion of the analysis of complex protein mixtures by 2D-electrophoresis and RPHPLC prior to sequencing by mass spectroscopy. Written with the student firmly in mind, no previous knowledge of biochemistry, and little of chemistry, is assumed. It is intended to provide an introduction to enzymology, and a balanced account of all the various theoretical and applied aspects of the subject which are likely to be included in a course.

    The book also pursues the major contribution that Levi-Strauss has made to contempoary aesthetic theory.

    Covering everything from ancient herbs to cutting-edge chemicals, this book in the hugely popular Milestones series looks at 250 of the most important moments in the development of life-altering, life-saving, and sometimes life-endangering pharmaceuticals. Illustrated entries feature ancient drugs like alcohol, opium, and hemlock; the smallpox and the polio vaccines; homeopathic cures; and controversial medical treatments like ether, amphetamines, and Xanax—while shining a light on the scientists, doctors, and companies who brought them to us.

    It sustainably provided enough food to allow cities, nations, and empires to grow, but it did so with a different emphasis. Where agriculture encouraged stability, fishing demanded movement. It frequently required a search for new and better fishing grounds; its technologies, centered on boats, facilitated movement and discovery; and fish themselves, when dried and salted, were the ideal food—lightweight, nutritious, and long-lasting—for traders, travelers, and conquering armies. This history of the long interaction of humans and seafood tours archaeological sites worldwide to show readers how fishing fed human settlement, rising social complexity, the development of cities, and ultimately the modern world.

    Among many stunning innovations, they helped invent our electronic battlefield and Star Wars missile defense technology, and are now looking into ways to improve our intelligence gathering. Recounting the unknown story of these brilliant, stubbornly independent thinkers, Ann Finkbeiner takes advantage of her unprecedented access to this elite group to explore the uncertain bargains between science and politics. It is a story older than Faust and as timely as tomorrow's headlines.

    They have also become vibrant educational centers, full of engaging exhibits that share those discoveries with students and an enthusiastic general public.   At the heart of it all from the very start have been curators. Yet after three decades as a natural history curator, Lance Grande found that he still had to explain to people what he does. This book is the answer—and, oh, what an answer it is: lively, exciting, up-to-date, it offers a portrait of curators and their research  like none we’ve seen, one that conveys the intellectual excitement and the educational and social value of curation. Grande uses the personal story of his own career—most of it spent at Chicago’s storied Field Museum—to structure his account as he explores the value of research and collections, the importance of public engagement, changing ecological and ethical considerations, and the impact of rapidly improving technology. Throughout, we are guided by Grande’s keen sense of mission, of a job where the why is always as important as the what.   This beautifully written and richly illustrated book is a clear-eyed but loving account of natural history museums, their curators, and their ever-expanding roles in the twenty-first century.

    Pairing Charles Darwin and a rare species of barnacle as her unlikely protagonists, Rebecca Stott has written an absorbing work of history that guides readers through the treacherous shoals of nineteenth-century biology. Beginning her scientific detective story in the 1820s, even before Darwin's Beagle voyage, Stott examines the mystery of why Darwin waited over two decades between formulating his pivotal theory of natural selection and publishing it. Lavishly illustrated, filled with riddles and concepts that challenge our notion of Victorian science, Darwin and the Barnacle is a thrilling account of how genius proceeds through indirection—and how one small item of curiosity contributed to history's most spectacular scientific breakthrough.

    A classic of scientific discovery that reveals to us the fullest picture yet of Neolithic man, our ancestor.

    But was it a savage sheep killer or a shy, fussy, nocturnal feeder? And did it really drink its victims' blood? Once reviled, feared and slaughtered by government decree, the myth of the Tasmanian Tiger continues to grow. So treasured is it now, the Tasmanian Tiger has become the official logo of the island that wiped it out and a symbol of the conservation movement world-wide.A number of Australian species have miraculously reappeared after being labelled as extinct. Perhaps the Tiger is still with us. And if it's not, can it be brought back by cloning?

    Unseen but listening intently was an audience of more than a billion people.It was Christmas Eve, 1968. And the astronauts of Apollo 8 -- Commander Frank Borman, Jim Lovell, and Bill Anders -- were participants in a mission that took them farther (500,000 miles) and faster (24,000 miles an hour) than any human had ever traveled. Of the 27 previous manned launches, none had ever ventured higher than 850 miles in altitude. Apollo 8 was the first manned vehicle to leave the earth's orbit and the first craft to orbit the moon.Confined within a tiny 11 x 13-foot capsule -- the size of the interior of a 15-passenger van -- the astronauts were aided in their journey by a computer less powerful than one of today's least sophisticated handheld calculators. The mission was not only a triumph of engineering, but also an enduring moment in history. It was a triumph for America and its space agency, and assured the public's continued interest in exploring space.

    Bavin U.S. Fish and Wildlife Service Forensics Laboratory lies a rarely seen world, a CSI for wildlife, where a walk-in freezer contains carcasses and animal parts awaiting necropsies (animal autopsies); shelves and drawers hold pills, rugs, carvings, and countless other products made from parts of endangered animals; and a dedicated group of forensic scientists is responsible for victims from thirty thousand animal species. Accomplished environmental journalist Laurel A. Neme goes behind the scenes at the wildlife forensics lab -- the only crime lab of its kind -- to reveal how its forensic scientists and the agents of the U.S. Fish and Wildlife Service are working to investigate wildlife crimes, protect endangered species, and stem illegal wildlife trafficking, the third largest illegal trade in the world. In three fascinating cases -- headless walrus washed up on the shores of Alaska, black bears killed for the healing powers of their gallbladders, and gorgeous feathered headdresses secretly shipped to the United States from the Amazon -- Neme traces the USFWS's daring undercover investigations and how the scientists' innovative forensic techniques provide conclusive evidence of a crime. Throughout, she underscores the staggering international scope of the supply and demand for wildlife and animal parts. Filled with the suspense and thrilling detail of a crime novel yet driven by the all-too-real drama of a small band of scientists and investigators battling a lucrative, high-stakes underground industry, Animal Investigators is an engrossing account of crime and cutting-edge science.

    The book features case discussions, USMLE-style questions, and a USMLE-style practice exam.

    Here are the stories of forty of the world’s greatest explorers from Europe, America, Asia, and Australia. These are men and women who changed our perception of the world through their courageous adventures.Organized thematically, the book opens with the oceanic journeys of five hundred years ago, when the great era of recorded exploration began. The following sections look at The Land, Rivers, Polar Ice, Deserts, Life on Earth, and New Frontiers.Many of these explorers recounted their journeys in vivid firsthand accounts; others were superb artists or photographers. The book features quotes from their journals and reports, and it is illustrated with paintings, photographs, engravings, and maps, so that we can experience their adventures through their own eyes and in their own words.Featured explorers include: Christopher Columbus, Vasco da Gama, James Cook, Lewis and Clark, Richard Burton, Samuel de Champlain, David Livingstone, Roald Amundsen, Gertrude Bell, Alexander von Humboldt, Yuri Gagarin, and Jacques-Yves Cousteau.

    Today, more than sixty years later, members of a new generation of scientists are attempting to create life from the ground up. Science has moved forward in leaps and bounds since Schrodinger's time, but our understanding of what does and does not constitute life has only grown more complex. An era that has already seen computer chip-implanted human brains, genetically engineered organisms, genetically modified foods, cloned mammals, and brain-dead humans kept alive by machines is one that demands fresh thinking about the concept of life. While a segment of our national debate remains stubbornly mired in moral quandaries over abortion, euthanasia, and other right to life issues, the science writer Ed Regis demonstrates how science can and does provide us with a detailed understanding of the nature of life. Written in a lively and accessible style, and synthesizing a wide range of contemporary research, What Is Life? is a brief and illuminating contribution to an age-old debate.