This was the world of medicine when Thomas Dent Mütter began his trailblazing career as a plastic surgeon in Philadelphia during the middle of the nineteenth century.Although he died at just forty-eight, Mütter was an audacious medical innovator who pioneered the use of ether as anesthesia, the sterilization of surgical tools, and a compassion-based vision for helping the severely deformed, which clashed spectacularly with the sentiments of his time.   Brilliant, outspoken, and brazenly handsome, Mütter was flamboyant in every aspect of his life. He wore pink silk suits to perform surgery, added an umlaut to his last name just because he could, and amassed an immense collection of medical oddities that would later form the basis of Philadelphia’s Mütter Museum. Cristin O’Keefe Aptowicz chronicles how Mütter’s efforts helped establish Philadelphia as a global mecca for medical innovation—despite intense resistance from his numerous rivals.

    Charles Darwin played a crucial part in turning heredity into a scientific question, and yet he failed spectacularly to answer it. The birth of genetics in the early 1900s seemed to do precisely that. Gradually, people translated their old notions about heredity into a language of genes. As the technology for studying genes became cheaper, millions of people ordered genetic tests to link themselves to missing parents, to distant ancestors, to ethnic identities. . . .But, Zimmer writes, "Each of us carries an amalgam of fragments of DNA, stitched together from some of our many ancestors. Each piece has its own ancestry, traveling a different path back through human history. A particular fragment may sometimes be cause for worry, but most of our DNA influences who we are--our appearance, our height, our penchants--in inconceivably subtle ways." Heredity isn't just about genes that pass from parent to child. Heredity continues within our own bodies, as a single cell gives rise to trillions of cells that make up our bodies. We say we inherit genes from our ancestors--using a word that once referred to kingdoms and estates--but we inherit other things that matter as much or more to our lives, from microbes to technologies we use to make life more comfortable. We need a new definition of what heredity is and, through Carl Zimmer's lucid exposition and storytelling, this resounding tour de force delivers it. Weaving historical and current scientific research, his own experience with his two daughters, and the kind of original reporting expected of one of the world's best science journalists, Zimmer ultimately unpacks urgent bioethical quandaries arising from new biomedical technologies, but also long-standing presumptions about who we really are and what we can pass on to future generations.

    He is beloved around the world for his pioneering detective fiction, tales of horror, and haunting, atmospheric verse. But what if there was another side to the man who wrote "The Raven" and "The Fall of the House of Usher"?In The Reason for the Darkness of the Night, John Tresch offers a bold new biography of a writer whose short, tortured life continues to fascinate. Shining a spotlight on an era when the lines separating entertainment, speculation, and scientific inquiry were blurred, Tresch reveals Poe's obsession with science and lifelong ambition to advance and question human knowledge. Even as he composed dazzling works of fiction, he remained an avid and often combative commentator on new discoveries, publishing and hustling in literary scenes that also hosted the era's most prominent scientists, semi-scientists, and pseudo-intellectual rogues. As one newspaper put it, "Mr. Poe is not merely a man of science--not merely a poet--not merely a man of letters. He is all combined; and perhaps he is something more."Taking us through his early training in mathematics and engineering at West Point and the tumultuous years that followed, Tresch shows that Poe lived, thought, and suffered surrounded by science--and that many of his most renowned and imaginative works can best be understood in its company. He cast doubt on perceived certainties even as he hungered for knowledge, and at the end of his life delivered a mind-bending lecture on the origins of the universe that would win the admiration of twentieth-century physicists. Pursuing extraordinary conjectures and a unique aesthetic vision, he remained a figure of explosive contradiction: he gleefully exposed the hoaxes of the era's scientific fraudsters even as he perpetrated hoaxes himself.Tracing Poe's hard and brilliant journey, The Reason for the Darkness of the Night is an essential new portrait of a writer whose life is synonymous with mystery and imagination--and an entertaining, erudite tour of the world of American science just as it was beginning to come into its own.

    The prolonged encounter between the Cro-Magnons and the archaic Neanderthals and between 45,000 and 30,000 years ago was one of the defining moments of history. The Neanderthals survived for some 15,000 years in the face of the newcomers, but were finally pushed aside by the Cro-Magnons' vastly superior intellectual abilities and cutting-edge technologies, which allowed them to thrive in the intensely challenging climate of the Ice Age.What do we know about this remarkable takeover? Who were the first modern Europeans and what were they like? How did they manage to thrive in such an extreme environment? And what legacy did they leave behind them after the cold millennia? The age of the Cro-Magnons lasted some 30,000 years?longer than all of recorded history. Cro-Magnon is the story of a little known, yet seminal, chapter of human experience.

    Priestley represented a unique synthesis: by the 1780s, he had established himself as one of the world's most celebrated scientists, most prominent religious figures, and most outspoken political thinkers. Yet he would also have become one of the most hated men in all of his native England. When an angry mob burned down his house in Birmingham, Priestley and his family set sail for Pennsylvania.In the nascent United States, Priestley hoped to find the freedom to bridge the disciplines that had governed his life, to find a quiet lab and a receptive pulpit. Once he arrived, as a result of his close relationships with the Founding Fathers—Jefferson credited Priestley as the man who prevented him from abandoning Christianity—Priestley found himself at the center of what would go down as one of the seminal debates in American history. And as Johnson brilliant charts, Priestley exerted profound if little-known influence on the shape and course of this great experiment in nation-building.As in his most recent bestselling work, The Ghost Map, Steven Johnson here uses a dramatic historical story to explore themes that have long engaged him: innovation and the way new ideas emerge and spread, and the environments that foster these breakthroughs. As he did in Everything Bad is Good for You, he upsets some fundamental assumptions about the world we live in—namely, what it means when we invoke the Founding Fathers—and replaces them with a clear-eyed, eloquent assessment of where we stand today.

    Nobody is perfect. And that includes five of the greatest scientists in history—Charles Darwin, William Thomson (Lord Kelvin), Linus Pauling, Fred Hoyle, and Albert Einstein. But the mistakes that these great luminaries made helped advance science. Indeed, as Mario Livio explains, science thrives on error, advancing when erroneous ideas are disproven.As a young scientist, Einstein tried to conceive of a way to describe the evolution of the universe at large, based on General Relativity—his theory of space, time, and gravity. Unfortunately he fell victim to a misguided notion of aesthetic simplicity. Fred Hoyle was an eminent astrophysicist who ridiculed an emerging theory about the origin of the universe that he dismissively called “The Big Bang.” The name stuck, but Hoyle was dead wrong in his opposition.They, along with Darwin (a blunder in his theory of Natural Selection), Kelvin (a blunder in his calculation of the age of the earth), and Pauling (a blunder in his model for the structure of the DNA molecule), were brilliant men and fascinating human beings. Their blunders were a necessary part of the scientific process. Collectively they helped to dramatically further our knowledge of the evolution of life, the Earth, and the universe.

    Jail attendants said they understood she was held in connection with the shooting of an airline pilot.'Petite, glamorous and beguiling, Jessie 'Chubbie' Miller was one remarkable woman ... flyer, thrill seeker, heartbreaker. No adventure was too wild for her, no danger too extreme. And all over the world men adored her.When the young Jessie left suburban Melbourne and her newspaperman husband in 1927, little did she know that she'd become the first woman to complete an England to Australia flight (with a black silk gown thrown into her small flight bag, just in case), or fly the first air race for women with Amelia Earhart, or that she would disappear over the Florida Straits feared lost forever only to charm her way to a rescue. Nor could she have predicted that five years later she'd find herself at the centre of one of the most notorious and controversial murder trials in United States history. And this all began with something as ridiculously mundane as a pat of butter.The Fabulous Flying Mrs Miller is a spellbinding story of an extraordinary woman - an international celebrity during the golden age of aviation - and her passionate and spirited life.

    Einstein in BerlinIn the spring of 1913 two of the giants of modern science traveled to Zurich. Their mission: to offer the most prestigious position in the very center of European scientific life to a man who had just six years before been a mere patent clerk. Albert Einstein accepted, arriving in Berlin in March 1914 to take up his new post. In December 1932 he left Berlin forever. “Take a good look,” he said to his wife as they walked away from their house. “You will never see it again.”In between, Einstein’s Berlin years capture in microcosm the odyssey of the twentieth century. It is a century that opens with extravagant hopes--and climaxes in unparalleled calamity. These are tumultuous times, seen through the life of one man who is at once witness to and architect of his day--and ours. He is present at the events that will shape the journey from the commencement of the Great War to the rumblings of the next one. We begin with the eminent scientist, already widely recognized for his special theory of relativity. His personal life is in turmoil, with his marriage collapsing, an affair under way. Within two years of his arrival in Berlin he makes one of the landmark discoveries of all time: a new theory of gravity--and before long is transformed into the first international pop star of science. He flourishes during a war he hates, and serves as an instrument of reconciliation in the early months of the peace; he becomes first a symbol of the hope of reason, then a focus for the rage and madness of the right. And throughout these years Berlin is an equal character, with its astonishing eruption of revolutionary pathways in art and architecture, in music, theater, and literature. Its wild street life and sexual excesses are notorious. But with the debacle of the depression and Hitler’s growing power, Berlin will be transformed, until by the end of 1932 it is no longer a safe home for Einstein. Once a hero, now vilified not only as the perpetrator of “Jewish physics” but as the preeminent symbol of all that the Nazis loathe, he knows it is time to leave.From the Hardcover edition.

    The expedition was described by the two men in Sea of Cortez, published in 1941. The day-to-day story of the trip is told here in the Log, which combines science, philosophy and high-spirited adventure.Log from the Sea of Cortez includes the narrative of the journey and the essay “About Ed Ricketts.” It does not include pictures and detailed descriptions of the species collected by Steinbeck and Ricketts. (See also Sea of Cortez.)

    Created by a Hungarian nobleman, the machine-man known as The Turk traveled Europe and America, made the acquaintance of Benjamin Franklin, Catherine the Great, Napoleon Bonaparte, and Edgar Allan Poe.

    With his own research as well as that of some of the most distinguished scientists of our time, Schäfer moves us from a reality of Darwinian competition to cooperation, a meaningless universe to a meaningful one, and a disconnected, isolated existence to an interconnected one. In so doing, he shows us that our potential is infinite and calls us to live in accordance with the order of the universe, creating a society based on the cosmic principle of connection, emphasizing cooperation and community.

    Inspired by his outrage at Edmund Burke’s attack on the French Revolution, Paine’s text is a passionate defense of man’s inalienable rights. Since its publication, Rights of Man has been celebrated, criticized, maligned, suppressed, and co-opted. But in Thomas Paine’s Rights of Man, the polemicist and commentator Christopher Hitchens, “at his characteristically incisive best,” marvels at its forethought and revels in its contentiousness (The Times, London). Hitchens is a political descendant of the great pamphleteer, “a Tom Paine for our troubled times.” (The Independent, London) In this “engaging account of Paine’s life and times [that is] well worth reading” he demonstrates how Paine’s book forms the philosophical cornerstone of the United States, and how, “in a time when both rights and reason are under attack,” Thomas Paine’s life and writing “will always be part of the arsenal on which we shall need to depend.” (New Statesman)

    Shrouded in mystery, Gregor Mendel's quiet life and discoveries make for fascinating reading. Among his pea plants Henig finds a tale filled with intrigue, jealousy, and a healthy dose of bad timing. She "has done a remarkable job of fleshing out the myth with what few facts there are" (Washington Post Book World) and has delivered Mendel's story with grace and glittering prose. THE MONK IN THE GARDEN is both a "classic tale of redemption" (New York Times Book Review) and a science book of the highest literary order.

    The fascinating tales in The Disappearing Spoon follow carbon, neon, silicon, gold and every single element on the table as they play out their parts in human history, finance, mythology, conflict, the arts, medicine and the lives of the (frequently) mad scientists who discovered them.Why did a little lithium (Li, 3) help cure poet Robert Lowell of his madness? And how did gallium (Ga, 31) become the go-to element for laboratory pranksters? The Disappearing Spoon has the answers, fusing science with the classic lore of invention, investigation, discovery and alchemy, from the big bang through to the end of time.

    Houbolt, an unsung hero of Apollo 11 and the man who showed NASA how to put America on the moon. Without John C. Houbolt, a junior engineer at NASA, Apollo 11 would never have made it to the moon. Top NASA engineers on the project, including Werner Von Braun, strongly advocated for a single, huge spacecraft to travel to the moon, land, and return to Earth. It's the scenario used in 1950s cartoons and horror movies about traveling to outer space. Houbolt had another idea: Lunar Orbit Rendezvous. LOR would link two spacecraft in orbit while the crafts were travelling at 17,000 miles per hour. His plan was ridiculed and considered unthinkable. But this junior engineer was irrepressible. He stood by his concept, fired off memos to executives, and argued that LOR was the only way to success. For the 50th anniversary of Apollo 11, hear the untold story of the man who helped fulfill Kennedy’s challenge to reach the moon and begin exploring the final frontier.