Whether eating, taking drugs, engaging in sex, or doing good deeds, the pursuit of pleasure is a central drive of the human animal. In The Compass of Pleasure Johns Hopkins neuroscientist David J. Linden explains how pleasure affects us at the most fundamental level: in our brain. As he did in his award-winning book, The Accidental Mind, Linden combines cutting-edge science with entertaining anecdotes to illuminate the source of the behaviors that can lead us to ecstasy but that can easily become compulsive. Why are drugs like nicotine and heroin addictive while LSD is not? Why has the search for safe appetite suppressants been such a disappointment? The Compass of Pleasure concludes with a provocative consideration of pleasure in the future, when it may be possible to activate our pleasure circuits at will and in entirely novel patterns.

    Unveiling here the kind of cutting-edge research that has made them giants in their fields, Daniel Goleman and Richard Davidson show us the truth about what meditation can really do for us, as well as exactly how to get the most out of it.Sweeping away common misconceptions and neuromythology to open readers' eyes to the ways data has been distorted to sell mind-training methods, the authors demonstrate that beyond the pleasant states mental exercises can produce, the real payoffs are the lasting personality traits that can result. But short daily doses will not get us to the highest level of lasting positive change--even if we continue for years--without specific additions. More than sheer hours, we need smart practice, including crucial ingredients such as targeted feedback from a master teacher and a more spacious, less attached view of the self, all of which are missing in widespread versions of mind training. The authors also reveal the latest data from Davidson's own lab that point to a new methodology for developing a broader array of mind-training methods with larger implications for how we can derive the greatest benefits from the practice.Exciting, compelling, and grounded in new research, this is one of those rare books that has the power to change us at the deepest level.

    Exploring and participating in the cultures that have grown up around these drugs while consuming (or, in the case of caffeine, trying not to consume) them, Pollan reckons with the powerful human attraction to psychoactive plants. Why do we go to such great lengths to seek these shifts in consciousness, and then why do we fence that universal desire with laws and customs and fraught feelings?

    Sapolsky's acclaimed and successful Why Zebras Don't Get Ulcers features new chapters on how stress affects sleep and addiction, as well as new insights into anxiety and personality disorder and the impact of spirituality on managing stress.As Sapolsky explains, most of us do not lie awake at night worrying about whether we have leprosy or malaria. Instead, the diseases we fear--and the ones that plague us now--are illnesses brought on by the slow accumulation of damage, such as heart disease and cancer. When we worry or experience stress, our body turns on the same physiological responses that an animal's does, but we do not resolve conflict in the same way--through fighting or fleeing. Over time, this activation of a stress response makes us sick.

    With his classic Why We Get Sick, Dr. Randolph Nesse helped to establish the field of evolutionary medicine. Now he returns with a book that transforms our understanding of mental disorders by exploring a fundamentally new question. Instead of asking why certain people suffer from mental illness, Nesse asks why natural selection has left us all with fragile minds.Drawing on revealing stories from his own clinical practice and insights from evolutionary biology, Nesse shows how negative emotions are useful in certain situations, yet can become overwhelming. Anxiety protects us from harm in the face of danger, but false alarms are inevitable. Low moods prevent us from wasting effort in pursuit of unreachable goals, but they often escalate into pathological depression. Other mental disorders, such as addiction and anorexia, result from the mismatch between modern environment and our ancient human past. And there are good evolutionary reasons for sexual disorders and for why genes for schizophrenia persist. Taken together, these and many more insights help to explain the pervasiveness of human suffering, and show us new paths for relieving it by understanding individuals as individuals.

    Scientists have long supported this assumption by claiming that emotions are hardwired in the body or the brain. Today, however, the science of emotion is in the midst of a revolution on par with the discovery of relativity in physics and natural selection in biology—ans this paradigm shift has far-reaching implications for us all.Leading the charge is psychologist and neuroscientist Lisa Feldman Barrett, whose theory of emotion is driving a deeper understanding of the mind and brain, and shedding new light on what it means to be human. Her research overturns the widely held belief that emotions are housed in different parts of the brain and are universally expressed and recognized. Instead, she has shown that emotion is constructed in the moment, by core systems that interact across the whole brain, aided by a lifetime of learning. This new theory means that you play a much greater role in your emotional life than you ever thought. Its repercussions are already shaking the foundations not only of psychology but also of medicine, the legal system, child-rearing, meditation, and even airport security.Why do emotions feel automatic? Does rational thought really control emotion? How does emotion affect disease? How can you make your children more emotionally intelligent? How Emotions Are Made answers these questions and many more, revealing the latest research and intriguing practical applications of the new science of emotion, mind, and brain.

    Life remains the only way to make life. Are we still missing a vital ingredient in its creation?      Like Richard Dawkins' The Selfish Gene, which provided a new perspective on how evolution works, Life on the Edge alters our understanding of our world's fundamental dynamics. Bringing together first-hand experience at the cutting edge of science with unparalleled gifts of explanation, Jim Al-Khalili and Johnjoe Macfadden reveal that missing ingredient to be quantum mechanics; the phenomena that lie at the heart of this most mysterious of sciences. Drawing on recent ground-breaking experiments around the world, each chapter in Life on the Edge engages by illustrating one of life's puzzles: How do migrating birds know where to go? How do we really smell the scent of a rose? How do our genes copy themselves with such precision? Life on the Edge accessibly reveals how quantum mechanics can answer these probing questions of the universe. Guiding the reader through the rapidly unfolding discoveries of the last few years, Al-Khalili and McFadden communicate the excitement of the explosive new field of quantum biology and its potentially revolutionary applications, while offering insights into the biggest puzzle of all: what is life? As they brilliantly demonstrate in these groundbreaking pages, life exists on the quantum edge.

    Told here for the first time, the dramatic tale of how the secrets of the brain were discovered in seventeenth-century England unfolds against a turbulent backdrop of civil war, the Great Fire of London, and plague. At the beginning of that chaotic century, no one knew how the brain worked or even what it looked like intact. But by the century's close, even the most common conceptions and dominant philosophies had been completely overturned, supplanted by a radical new vision of man, God, and the universe. Presiding over the rise of this new scientific paradigm was the founder of modern neurology, Thomas Willis, a fascinating, sympathetic, even heroic figure at the center of an extraordinary group of scientists and philosophers known as the Oxford circle. Chronicled here in vivid detail are their groundbreaking revelations and the often gory experiments that first enshrined the brain as the physical seat of intelligence -- and the seat of the human soul. Soul Made Flesh conveys a contagious appreciation for the brain, its structure, and its many marvelous functions, and the implications for human identity, mind, and morality.

    Too often, textbooks turn the fascinating systems, processes, and figures of anatomy into tedious discourse that even Leonardo Da Vinci would reject. This easy-to-read guide cuts out the boring details, and instead, provides you with a compelling lesson in anatomy. Covering every aspect of anatomical development and physiology, each chapter details the different parts of the human body, how systems are formed, and disorders that could disrupt bodily functions. You'll unravel the mysteries of anatomy with unique, accessible elements like: Detailed charts of each system in the body Illustrations of cross sections Unique profiles of the most influential figures in medical history From cell chemistry to the respiratory system, Anatomy 101 is packed with hundreds of entertaining facts that you can't get anywhere else!

    Prusiner received a Nobel Prize, the world's most prestigious award for achievement in physiology or medicine. That he was the sole recipient of the award for the year was entirely appropriate, for his struggle to identify the agent responsible for ravaging the brains of animals suffering from scrapie and mad cow disease, and of humans with Creutzfeldt-Jakob disease, had been waged largely alone and in some cases in the face of strenuous disagreement.   In this book, Prusiner tells the remarkable story of his discovery of prions—infectious proteins that replicate and cause disease but surprisingly contain no genetic material—and reveals how superb and meticulous science is actually practiced using talented teams of researchers who persevere. He recounts the frustrations and rewards of years of research and offers fascinating portraits of his peers as they raced to discover the causes of fatal brain diseases. Prusiner’s hypothesis, once considered heresy, now stands as accepted science and the basis for developing diagnoses and eventual cures. He closes with a meditation on the legacy of his discovery: What will it take to cure Alzheimer’s, Parkinson’s, Lou Gehrig’s and other devastating diseases of the brain?

    Fascinating... may presage a paradigm shift in medicine." --Kirkus Reviews (starred review)Teeming with information and big ideas... Outstanding."--Booklist (starred review) The origin of asthma, autism, Alzheimer's, allergies, cancer, heart disease, obesity, and even some kinds of depression is now clear. Award-winning researcher on the microbiome, professor Rodney Dietert presents a new paradigm in human biology that has emerged in the midst of the ongoing global epidemic of noncommunicable diseases.The Human Superorganism makes a sweeping, paradigm-shifting argument. It demolishes two fundamental beliefs that have blinkered all medical thinking until very recently: 1) Humans are better off as pure organisms free of foreign microbes; and 2) the human genome is the key to future medical advances. The microorganisms that we have sought to eliminate have been there for centuries supporting our ancestors. They comprise as much as 90 percent of the cells in and on our bodies--a staggering percentage! More than a thousand species of them live inside us, on our skin, and on our very eyelashes. Yet we have now significantly reduced their power and in doing so have sparked an epidemic of noncommunicable diseases--which now account for 63 percent of all human deaths.Ultimately, this book is not just about microbes; it is about a different way to view humans. The story that Dietert tells of where the new biology comes from, how it works, and the ways in which it affects your life is fascinating, authoritative, and revolutionary. Dietert identifies foods that best serve you, the superorganism; not new fad foods but ancient foods that have made sense for millennia. He explains protective measures against unsafe chemicals and drugs. He offers an empowering self-care guide and the blueprint for a revolution in public health. We are not what we have been taught. Each of us is a superorganism. The best path to a healthy life is through recognizing that profound truth.

    Sleep patterns may be the most obvious manifestation of the highly individualized biological clocks we inherit, but these clocks also regulate bodily functions from digestion to hormone levels to cognition. Living at odds with our internal timepieces, Till Roenneberg shows, can make us chronically sleep deprived and more likely to smoke, gain weight, feel depressed, fall ill, and fail geometry. By understanding and respecting our internal time, we can live better.Internal Time combines storytelling with accessible science tutorials to explain how our internal clocks work—for example, why morning classes are so unpopular and why “lazy” adolescents are wise to avoid them. We learn why the constant twilight of our largely indoor lives makes us dependent on alarm clocks and tired, and why social demands and work schedules lead to a social jet lag that compromises our daily functioning.Many of the factors that make us early or late “chronotypes” are beyond our control, but that doesn’t make us powerless. Roenneberg recommends that the best way to sync our internal time with our external environment and feel better is to get more sunlight. Such simple steps as cycling to work and eating breakfast outside may be the tickets to a good night’s sleep, better overall health, and less grouchiness in the morning.[Description taken from publisher's web site.]

    In You Are the Placebo, Dr. Joe Dispenza shares numerous documented cases of those who reversed cancer, heart disease, depression, crippling arthritis, and even the tremors of Parkinson’s disease by believing in a placebo. Similarly, Dr. Joe tells of how others have gotten sick and even died the victims of a hex or voodoo curse—or after being misdiagnosed with a fatal illness. Belief can be so strong that pharmaceutical companies use double- and triple-blind randomized studies to try to exclude the power of the mind over the body when evaluating new drugs.     Dr. Joe does more than simply explore the history and the physiology of the placebo effect. He asks the question: “Is it possible to teach the principles of the placebo, and without relying on any external substance, produce the same internal changes in a person’s health and ultimately in his or her life?” Then he shares scientific evidence (including color brain scans) of amazing healings from his workshops, in which participants learn his model of personal transformation, based on practical applications of the so-called placebo effect. The book ends with a “how-to” meditation for changing beliefs and perceptions that hold us back—the first step in healing.     You Are the Placebo combines the latest research in neuroscience, biology, psychology, hypnosis, behavioral conditioning, and quantum physics to demystify the workings of the placebo effect . . . and show how the seemingly impossible can become possible.

    Charting the most cutting-edge scientific breakthroughs, and marshalling his decades of research and clinical practice, Walker explains how we can harness sleep to improve learning, mood and energy levels, regulate hormones, prevent cancer, Alzheimer's and diabetes, slow the effects of aging, and increase longevity. He also provides actionable steps towards getting a better night's sleep every night.

    Spanning evolutionary science from its inception to its latest findings, from discoveries and data to philosophy and history, this book is an authoritative introduction to evolutionary biology.