Beginning with his family’s odyssey, In a Different Key tells the extraordinary story of this often misunderstood condition, and of the civil rights battles waged by the families of those who have it. Unfolding over decades, it is a beautifully rendered history of ordinary people determined to secure a place in the world for those with autism—by liberating children from dank institutions, campaigning for their right to go to school, challenging expert opinion on what it means to have autism, and persuading society to accept those who are different.  It is the story of women like Ruth Sullivan, who rebelled against a medical establishment that blamed cold and rejecting “refrigerator mothers” for causing autism; and of fathers who pushed scientists to dig harder for treatments. Many others played starring roles too: doctors like Leo Kanner, who pioneered our understanding of autism; lawyers like Tom Gilhool, who took the families’ battle for education to the courtroom; scientists who sparred over how to treat autism; and those with autism, like Temple Grandin, Alex Plank, and Ari Ne’eman, who explained their inner worlds and championed the philosophy of neurodiversity. This is also a story of fierce controversies—from the question of whether there is truly an autism “epidemic,” and whether vaccines played a part in it; to scandals involving “facilitated communication,” one of many treatments that have proved to be blind alleys; to stark disagreements about whether scientists should pursue a cure for autism. There are dark turns too: we learn about experimenters feeding LSD to children with autism, or shocking them with electricity to change their behavior; and the authors reveal compelling evidence that Hans Asperger, discoverer of the syndrome named after him, participated in the Nazi program that consigned disabled children to death.<

    As the mosquito transformed the landscapes of civilization, humans were unwittingly required to respond to its piercing impact and universal projection of power.The mosquito has determined the fates of empires and nations, razed and crippled economies, and decided the outcome of pivotal wars, killing nearly half of humanity along the way. She (only females bite) has dispatched an estimated 52 billion people from a total of 108 billion throughout our relatively brief existence. As the greatest purveyor of extermination we have ever known, she has played a greater role in shaping our human story than any other living thing with which we share our global village.Imagine for a moment a world without deadly mosquitoes, or any mosquitoes, for that matter? Our history and the world we know, or think we know, would be completely unrecognizable.Driven by surprising insights and fast-paced storytelling, The Mosquito is the extraordinary untold story of the mosquito's reign through human history and her indelible impact on our modern world order.

    But these tiny insects, once merely a seasonal annoyance, now are capturing headlines worldwide as new information emerges about the diseases they carry, their migratory population, and their growing resistance to pesticides.Harvard professor Andrew Spielman has dedicated his life to understanding this insect, a passion that makes him the perfect guide to their amazing world and the perfect author of this lively, accessible book that offers an intriguing and horrifying mosquito-eye view of nature and man. He explains where mosquitoes breed, and how they die, showing us their natural foes and man-made enemies while explaining the myriad diseases they bring to all corners of the world. Spielman offers colorful examples of how the mosquito has insinuated itself into human history, from the defeat of Sir Francis Drake's fleet to the death of thousands of Frenchmen working on the Panama Canal to the recent widespread West Nile panic in New York City. Filled with little-known facts and illuminating anecdotes that bring this tiny being into larger focus, Mosquito offers fascinating, alarming, and convincing evidence that the sooner we get to know this little creature, the better off we'll be.

    Months later, several health professionals faced criminal allegations that they deliberately injected numerous patients with drugs to hasten their deaths. Five Days at Memorial, the culmination of six years of reporting, unspools the mystery of what happened in those days, bringing the reader into a hospital fighting for its life and into a conversation about the most terrifying form of health care rationing.In a voice at once involving and fair, masterful and intimate, Fink exposes the hidden dilemmas of end-of-life care and reveals just how ill-prepared we are in America for the impact of large-scale disasters—and how we can do better. A remarkable book, engrossing from start to finish, Five Days at Memorial radically transforms your understanding of human nature in crisis.

    William Maples can deduce the age, gender, and ethnicity of a murder victim, the manner in which the person was dispatched, and, ultimately, the identity of the killer.  In Dead Men Do Tell Tales, Dr. Maples revisits his strangest, most interesting, and most horrific investigations, from the baffling cases of conquistador Francisco Pizarro and Vietnam MIAs to the mysterious deaths of President Zachary Taylor and the family of Czar Nicholas II.

    Entering a room with stainless-steel tables topped by corpses in body bags is shocking no matter how long you've prepared yourself, but a strange thing happened when Montross met her cadaver. Instead of being disgusted by her, she was utterly intrigued-intrigued by the person the woman once was, humbled by the sacrifice she had made in donating her body to science, fascinated by the strange, unsettling beauty of the human form. They called her Eve. This is the story of Montross and Eve-the student and the subject-and the surprising relationship that grew between them. Body of Work is a mesmerizing, rarely seen glimpse into the day-to-day life of a medical student-yet one that follows naturally in the footsteps of recent highly successful literary renderings of the mysteries of medicine such as Atul Gawande's Complications: A Surgeon's Notes on an Imperfect Science. Christine Montross was a poet long before she became a doctor and brings an uncommon perspective to the emotional difficulty of the first year of medical school-the dispiriting task of remaining clinical and detached while in the anatomy lab and the struggle with the line you've crossed by violating another's body once you leave it. Montross was so affected by her experience with Eve that she undertook to learn more about the history of cadavers and the study of anatomy. She visited an autopsy lab in Ireland and the University of Padua in Italy where Vesalius, a forefather of anatomy, once studied; she learned about body snatchers and grave-robbers and anatomists who practiced their work on live criminals. Her disturbing, often entertaining anecdotes enrich this exquisitely crafted memoir, endowing an eerie beauty to the world of a doctor-in-training. Body of Work is an unforgettable examination of the mysteries of the human body and a remarkable look at our relationship with both the living and the dead.

    Scourges that have plagued human beings since the ancients still threaten to unleash themselves; new maladies are brewing that have yet to make their appearance in the headlines; lethal germs employed as weapons of warfare and terrorism have reemerged as a worldwide menace. Regardless of their mode of attack, microbes exist to multiply, thrive, and find new hosts; they cross national boundaries and social classes, attacking without prejudice. Now medical historian and pediatrician Howard Markel, author of Quarantine! (“Engrossing . . . Meticulously documented” —Sherwin Nuland, The New Republic), tells the story of six epidemics that broke out during the two great waves of immigration to the United States—from 1880 through 1924, and from 1965 to the present—and shows how federal legislation closed the gates to newcomers for almost forty-one years out of fear that these new people would alter the social, political, economic, and even genetic face of the nation. Markel writes about tuberculosis today, the most serious public health threat facing the contemporary world. He writes about bubonic plague and how it came to this country in the early twentieth century; about trachoma in the years before World War I; about Ellis Island and how an East European rabbi was diagnosed and treated for the dreaded eye infection; about typhus fever and an epidemic on the Texas-Mexico border in the aftermath of Pancho Villa’s revolution; and about AIDS, the Haitian exodus, and the early years of the AIDS epidemic.Markel explains how immigration in the twenty-first century is characterized by porous borders, rapid travel, and scattered destinations. While more than 75 percent of all immigrants during the first great wave of immigration came through New York Harbor, transportation today allows travel to all parts of the United States from the farthest reaches of the globe, giving public health physicians little opportunity to definitively diagnose infectious diseases that can incubate silently in a traveler, making the spread of epidemics far more than a theoretical concern.Markel looks at our nation’s response to the pathogens present in our midst and examines our foolhardy attempts at isolation and our vacillation between demanding a public health system so punitive that it worsens matters rather than protects and settling for one that is too lax; how we are fascinated with all things infectious and then hardly give microbes a second thought; how the United States, a country that since its inception has prided itself on being a nation of immigrants, continues its tradition of blaming newcomers for its physical and social ills; and how globalization, social upheaval, and international travel render us all potential inhabitants of the so-called Hot Zone. Finally, Markel puts forth a plan for a globally funded public health program that could stop the spread of epidemics, help eradicate certain diseases, and protect us all.

    We may know a bit about Napoleon or Joan of Arc or Louis XIV, but for most of us that's about it. In my own three schools we were taught only about the battles we won: Crécy and Poitiers, Agincourt and Waterloo. The rest was silence. So here is my attempt to fill in the blanks... John Julius Norwich (at 88) has finally written the book he always wanted to write, the extremely colourful story of the country he loves best. From frowning Roman generals and belligerent Gallic chieftains, to Charlemagne (hated by generations of French children taught that he invented schools) through Marie Antoinette and the storming of the Bastille to Vichy, the Resistance and beyond, FRANCE is packed with heroes and villains, adventures and battles, romance and revolution. Full of memorable stories and racy anecdotes, this is the perfect introduction to the country that has inspired the rest of the world to live, dress, eat -- and love better.

    Egypt is stunningly beautiful with a pleasant climate year-round, and if that alone isn't a big enough draw for the time-traveler, the fruits of Egyptian civilization are plentiful and worthy of contemplation. Pyramids and temples to the gods abound, and colossal statues of Egypt's divine rulers are seemingly everywhere. The Egyptians, however, are not particularly fond of foreigners, and just getting to Egypt can be arduous. Here is the inside scoop on how to enter and travel through Egypt, conform to its customs and expectations, and appreciate its often mysterious culture. You'll travel the Nile from north to south, stopping at such intriguing places as Memphis, Akhetaten, Abydos, and Thebes, where Egypt's grand past and present unfold before you. Egypt has long been a subject of broad popular interest, and this book provides an enjoyable glimpse of the ancient empire and its industrious people. Advice for the traveler in ancient Egypt: Foreigners might be bewildered by animal-headed deities and what appear to be numerous contradictions in Egyptian theology. Not to worry: there's a system behind it. Don't bring up the topic of the renegade pharaoh, Akhenaten, among new acquaintances. Many wish he hadn't existed. Should you need to visit an Egyptian physician, there's agood chance he'll prescribe a purge of one sort or another, accompanied by a magic spell.

    Utilizing his background in medicine, he led the investigations of more than eight thousand individual deaths, becoming a key figure in some of New York’s most bizarre death cases and eventually taking charge of the largest forensic investigation ever attempted: identifying the dead in the aftermath of the September 11 tragedies.Now, in this mesmerizing book, Ribowsky pulls back the curtain on the New York City’s medical examiner’s office, giving an enthralling, never-before-seen glimpse into death and the city. Born and raised in New York City’s orthodox Jewish community, Ribowsky seems an unlikely candidate for this macabre profession. Nevertheless he has forsaken a promising career of medical work with the living, descending instead into the realm of the dead, enticed by the challenge of confronting death on a daily basis. Taking you through the vermin-infested Bowery flophouses and posh Upper East Side apartments of the city’s dead, Ribowsky explores in gruesome detail the skeletons that hang in the Big Apple’s closets. Combing through the autopsy room, he also exposes the grim secrets that only a scalpel and a dead body can tell and explains how forensic investigation does not merely solve crimes—it saves lives.But it is in the aftermath of September 11 that the ME’s office is handed its biggest challenge: to identify as many of the fallen as possible. With poignant descriptions, Ribowsky provides a dramatic account of the office’s diligent and unflappable work with the families of the victims, helping them emerge from the ashes of this tragedy while displaying the strength, grit, intelligence, and compassion that Americans expect from true New Yorkers.At once compelling and heartbreaking, Dead Center is a story of New York unlike any other, blending the haunting with the sublime, while painting a striking portrait of death (and life) in the city that never sleeps.

    Smallpox. Incurable and horrifying Ebola-related fevers. For two decades, while a fearful world prepared for nuclear winter, an elite team of Russian bioweaponeers began to till a new killing field: a bleak tract sown with powerful seeds of mass destruction—by doctors who had committed themselves to creating a biological Armageddon. Biohazard is the never-before-told story of Russia’s darkest, deadliest, and most closely guarded Cold War secret.   No one knows more about Russia’s astounding experiments with biowarfare than Ken Alibek. Now the mastermind behind Russia’s germ warfare effort reveals two decades of shocking breakthroughs . . . how Moscow’s leading scientists actually reengineered hazardous microbes to make them even more virulent . . . the secrets behind the discovery of an invisible, untraceable new class of biological agents just right for use in political assassinations . . . the startling story behind Russia’s attempt to turn a sample of the AIDS virus into the ultimate bioweapon. And in a chilling work of real-world intrigue, Biohazard offers us all a rare glimpse into a shadowy scientific underworld where doctors manufacture mass destruction, where witnesses to errors are silenced forever, and where ground zero is closer than we ever dared believe.

    There are no fences, no guards, no locked gates. But McLean Hospital is a mental institution-one of the most famous, most elite, and once most luxurious in America. McLean "alumni" include Olmsted himself, Robert Lowell, Sylvia Plath, James Taylor and Ray Charles, as well as (more secretly) other notables from among the rich and famous. In its "golden age," McLean provided as genteel an environment for the treatment of mental illness as one could imagine. But the golden age is over, and a downsized, downscale McLean-despite its affiliation with Harvard University-is struggling to stay afloat. Gracefully Insane, by Boston Globe columnist Alex Beam, is a fascinating and emotional biography of McLean Hospital from its founding in 1817 through today. It is filled with stories about patients and doctors: the Ralph Waldo Emerson prot'g' whose brilliance disappeared along with his madness; Anne Sexton's poetry seminar, and many more. The story of McLean is also the story of the hopes and failures of psychology and psychotherapy; of the evolution of attitudes about mental illness, of approaches to treatment, and of the economic pressures that are making McLean-and other institutions like it-relics of a bygone age. This is a compelling and often oddly poignant reading for fans of books like Plath's The Bell Jar and Susanna Kaysen's Girl, Interrupted (both inspired by their author's stays at McLean) and for anyone interested in the history of medicine or psychotherapy, or the social history of New England.

    Many people think of microbes as germs to be eradicated, but those that live with us—the microbiome—build our bodies, protect our health, shape our identities, and grant us incredible abilities. In this astonishing book, Ed Yong takes us on a grand tour through our microbial partners, and introduces us to the scientists on the front lines of discovery. Yong, whose humor is as evident as his erudition, prompts us to look at ourselves and our animal companions in a new light—less as individuals and more as the interconnected, interdependent multitudes we assuredly are. The microbes in our bodies are part of our immune systems and protect us from disease. Those in cows and termites digest the plants they eat. In the deep oceans, mysterious creatures without mouths or guts depend on microbes for all their energy. Bacteria provide squids with invisibility cloaks, help beetles to bring down forests, and allow worms to cause diseases that afflict millions of people. I Contain Multitudes is the story of these extraordinary partnerships, between the creatures we are familiar with and those we are not. It reveals how we humans are disrupting these partnerships and how we might manipulate them for our own good. It will change both our view of nature and our sense of where we belong in it.

    Confusing messages from health authorities and ineffective treatments have left many people desperate for reliable solutions. An enormous alternative industry is filling the void, selling products that are often of questionable safety and totally unknown effectiveness.In Clean, doctor and journalist James Hamblin explores how we got here, examining the science and culture of how we care for our skin today. He talks to dermatologists, microbiologists, allergists, immunologists, aestheticians, bar-soap enthusiasts, venture capitalists, Amish people, theologians, and straight-up scam artists, trying to figure out what it really means to be clean. He even experiments with giving up showers entirely, and discovers that he is not alone.Along the way he realizes that most of our standards of cleanliness are less related to health than most people think. A major part of the picture has been missing: a little-known ecosystem known as the skin microbiome--the trillions of microbes that live on our skin and in our pores. These microbes are not dangerous; they're more like an outer layer of skin that no one knew we had, and they influence everything from acne, eczema, and dry skin to how we smell. The new goal of skin care will be to cultivate a healthy biome--and to embrace the meaning of "clean" in the natural sense. This can mean doing much less, saving time, money, energy, water, and plastic bottles in the process.Lucid, accessible, and deeply researched, Clean explores the ongoing, radical change in the way we think about our skin, introducing readers to the emerging science that will be at the forefront of health and wellness conversations in coming years.

    From Simon & Schuster, Virus Ground Zero is Ed Regis' fascinating book about stalking the many killer viruses with The Center for Disease Control.An acclaimed science writer takes readers behind the scenes at the Centers for Disease Control to tell the story of an engrossing odyssey across the viral frontier.