The foundations of civilization and religion were raised and reinforced in this land of Togenkyo, the paradise known as Shangri-la.But now, a great evil threatens harmony in this great land. Far to the West, in India, someone is attempting to resurrect the youkai lord Gyumaoh by mixing human science with youkai magic. This forbidden practice has created a Minus Wave of negative energy that is spreading across Shangri-la, poisoning the souls of the youkai and turning them into mindless monsters. The only hope lies in four legendary heroes: Genjyo Sanzo, a high priest with low morals; Son Goku, the hungry and mischievous Monkey King, just released from 500 years imprisonment; Sha Gojyo, a water sprite with an addiction for good smokes and bad women; Cho Hakkai, the legendary demon slayer, and his transforming dragon Hakuryu. To save Shangri-la, these unlikely companions, united by fate, must travel together ... INTO THE WEST! Having been assigned by the human elders the mission of stopping a mystical plague that has afflicted the Youkai with madness, Genjyo Sanzo assembles his team of Youkai warriors, desperately hoping that the disease will not affect them. He sets up qualifying tests that will help him determine the loyalty and worth of Cho Hakkai, Son Goku and Sha Gojyo. The team then journeys west to rid the land of madness.

    Within this megastructure the silent, stoic Kyrii is on a mission to find the Net Terminal Gene—a genetic mutation that once allowed humans to access the cybernetic NetSphere. Armed with a powerful Graviton Beam Emitter, Kyrii fends off waves of attacks from fellow humans, cyborgs and silicon-based lifeforms. Along the way, he encounters a highly-skilled scientist whose body has deteriorated from a lengthy imprisonment who promises to help Kyrii find the Net Terminal Gene, once she settles a score for herself...