There have been exhilarating highs and devastating lows, but his love for the practice of neurosurgery has never wavered. Following the publication of his celebrated New York Times bestseller Do No Harm, Marsh retired from his full-time job in England to work pro bono in Ukraine and Nepal. In Admissions, he describes the difficulties of working in these troubled, impoverished countries and the further insights it has given him into the practice of medicine. Marsh also faces up to the burden of responsibility that can come with trying to reduce human suffering. Unearthing memories of his early days as a medical student and the experiences that shaped him as a young surgeon, he explores the difficulties of a profession that deals in probabilities rather than certainties and where the overwhelming urge to prolong life can come at a tragic cost for patients and those who love them. Reflecting on what forty years of handling the human brain has taught him, Marsh finds a different purpose in life as he approaches the end of his professional career and a fresh understanding of what matters to us all in the end.

    And, like most consumers, he often reads the ingredients label -- without a clue as to what most of it means. So when his young daughter asked, "Daddy, what's polysorbate 60?" he was at a loss -- and determined to find out. From the phosphate mines in Idaho to the corn fields in Iowa, from gypsum mines in Oklahoma to the vanilla harvest in Madagascar, Twinkie, Deconstructed is a fascinating, thoroughly researched romp of a narrative that demystifies some of the most common processed food ingredients -- where they come from, how they are made, how they are used -- and why. Beginning at the source (hint: they're often more closely linked to rock and petroleum than any of the four food groups), we follow each Twinkie ingredient through the process of being crushed, baked, fermented, refined, and/or reacted into a totally unrecognizable goo or powder with a strange name -- all for the sake of creating a simple snack cake. An insightful exploration into the food industry, if you've ever wondered what you're eating when you consume foods containing mono- and diglycerides or calcium sulfate (the latter, a food-grade equivalent) this book is for you.

    Brinkley–America’s most brazen young con man–arrived in the tiny town of Milford, Kansas. He set up a medical practice and introduced an outlandish surgical method using goat glands to restore the fading virility of local farmers.It was all nonsense, of course, but thousands of paying customers quickly turned “Dr.” Brinkley into America’s richest and most famous surgeon. His notoriety captured the attention of the great quackbuster Morris Fishbein, who vowed to put the country’s “most daring and dangerous” charlatan out of business.Their cat-and-mouse game lasted throughout the 1920s and ’30s, but despite Fishbein’s efforts Brinkley prospered wildly. When he ran for governor of Kansas, he invented campaigning techniques still used in modern politics. Thumbing his nose at American regulators, he built the world’s most powerful radio transmitter just across the Rio Grande to offer sundry cures, and killed or maimed patients by the score, yet his warped genius produced innovations in broadcasting that endure to this day. By introducing country music and blues to the nation, Brinkley also became a seminal force in rock ’n’ roll. In short, he is the most creative criminal this country has ever produced.Culminating in a decisive courtroom confrontation that pit Brinkley against his nemesis Fishbein, Charlatan is a marvelous portrait of a boundlessly audacious rogue on the loose in an America that was ripe for the bamboozling.

    It promised to shed light on the deep mysteries of consciousness, as well as offer relief to addicts and the mentally ill. But in the 1960s, with the vicious backlash against the counter-culture, all further research was banned. In recent years, however, work has quietly begun again on the amazing potential of LSD, psilocybin and DMT. Could these drugs in fact improve the lives of many people? Diving deep into this extraordinary world and putting himself forward as a guinea-pig, Michael Pollan has written a remarkable history of psychedelics and a compelling portrait of the new generation of scientists fascinated by the implications of these drugs. How to Change Your Mind is a report from what could very well be the future of human consciousness.

    Bundy's chilling revelations were chronicled in "The Riverman," "a page-turner" (Ted Montgomery, Detroit News ) praised by Ann Rule as "the definitive book on serials." But Ted Bundy wasn't the first killer of his kind - or the last "Signature Killers"They leave telltale identifiers, their gruesome "calling cards, " at the scenes of their crime. They are driven by a primitive motivation to act out the same brutality over and over. With brilliant detection, high-tech analysis - and a little luck - they can be caught. But what does the signature killer seek from victim to victim? The answers are hidden among the grisly evidence, the common threads that link each devastating act.Sparked by a growing concern over the steady rise of signature murders, Robert Keppel explores in unflinching detail the monstrous patterns, sadistic compulsions, and depraved motives of this breed of killer. From the Lonely Hearts Killer who hunted the most desperate of women in 1950s America, to the savage Midtown Torso Murders that stunned the NYPD, to such infamous symbols of evil as Jeffrey Dahmer, Ted Bundy, and John Gacy, these are the cases - horrifying, graphic and unforgettable - that Keppel ingeniously taps to shed light on the darkest corners of the pathological mind.

    She conjures up early operating theaters--no place for the squeamish--and surgeons, working before anesthesia, who were lauded for their speed and brute strength. These medical pioneers knew that the aftermath of surgery was often more dangerous than their patients' afflictions, and they were baffled by the persistent infections that kept mortality rates stubbornly high. At a time when surgery couldn't have been more hazardous, an unlikely figure stepped forward: a young, melancholy Quaker surgeon named Joseph Lister, who would solve the deadly riddle and change the course of history.Fitzharris dramatically recounts Lister's discoveries in gripping detail, culminating in his audacious claim that germs were the source of all infection--and could be countered by antiseptics. Focusing on the tumultuous period from 1850 to 1875, she introduces us to Lister and his contemporaries--some of them brilliant, some outright criminal--and takes us through the grimy medical schools and dreary hospitals where they learned their art, the deadhouses where they studied anatomy, and the graveyards they occasionally ransacked for cadavers.Eerie and illuminating, The Butchering Art celebrates the triumph of a visionary surgeon whose quest to unite science and medicine delivered us into the modern world.

    Richard Davenport-Hines, an eminent, prize-winning historian, uncovers the centrality of drug abuse in our modern industrial society, from the drug habits of Charles Dickens and John F. Kennedy to today's $400 billion annual worldwide trade in illicit drugs (the same volume as the oil industry). A vivid portrayal of the people and events that have shaped the history of narcotics, The Pursuit of Oblivion reveals that, contrary to the assumption underlying current drug policies, our need to escape reality and our body's need for physical pleasure are both ineradicable aspects of our humanity, unchangeable by government initiative.

    This elegant, humane, and engaging book "captures what we know of the development of what makes us human" (Nature).Visit Armand Marie Leroi on the web: http: //armandleroi.com/index.htmlStepping effortlessly from myth to cutting-edge science,

    But are there limits to what we can discover about our physical universe?In this very personal journey to the edges of knowledge, Marcus du Sautoy investigates how leading experts in fields from quantum physics and cosmology, to sensory perception and neuroscience, have articulated the current lie of the land. In doing so, he travels to the very boundaries of understanding, questioning contradictory stories and consulting cutting edge data.Is it possible that we will one day know everything? Or are there fields of research that will always lie beyond the bounds of human comprehension? And if so, how do we cope with living in a universe where there are things that will forever transcend our understanding?In What We Cannot Know, Marcus du Sautoy leads us on a thought-provoking expedition to the furthest reaches of modern science. Prepare to be taken to the edge of knowledge to find out if there’s anything we truly cannot know.

    In the mid-1970s, scientists began using DNA sequences to reexamine the history of all life. Perhaps the most startling discovery to come out of this new field—the study of life’s diversity and relatedness at the molecular level—is horizontal gene transfer (HGT), or the movement of genes across species lines. It turns out that HGT has been widespread and important. For instance, we now know that roughly eight percent of the human genome arrived not through traditional inheritance from directly ancestral forms, but sideways by viral infection—a type of HGT.David Quammen chronicles these discoveries through the lives of the researchers who made them—such as Carl Woese, the most important little-known biologist of the twentieth century; Lynn Margulis, the notorious maverick whose wild ideas about “mosaic” creatures proved to be true; and Tsutomu Wantanabe, who discovered that the scourge of antibiotic-resistant bacteria is a direct result of horizontal gene transfer, bringing the deep study of genome histories to bear on a global crisis in public health.

    Here are Einstein, Fleming, Bohr, McClintock, Paul ing, Watson and Crick, Heisenberg and many others. With remarkable insight, Lightman charts the intellectual and emotional landscape of the time, portrays the human drama of discovery, and explains the significance and impact of the work. Finally he includes a fascinating and unique guided tour through the original papers in which the discoveries were revealed. Here is science writing at its best–beautiful, lyrical and completely accessible. It brings the process of discovery to life before our very eyes.

    Two leading cardiologists draw on their collective fifty years of clinical cardiology research to show you how to combine the benefits of modern medicine, over-the-counter vitamins and supplements, and simple lifestyle changes to have a healthy heart.

    Here’s why: In the 1960s hunger was going global. Asia was wracked by famine, Latin America was hungry, and Africa was about to face the Sahel drought and massive starvation.Worse still, almost half the world’s 3 billion people were under the age of 30. Billions of babies were about to be born into a planet unable to feed them.Then a miracle occurred: the productivity of wheat doubled, tripled and in some places quadrupled. It happened in almost 100 countries all at once.Soon thereafter, the productivity of rice, corn and other cereals followed suit.Borlaug worked only with wheat but he set the trend toward making cereal crops efficient in using land, sunlight, growing time, and inputs, not to mention immune to major diseases.Nowadays his influence can be seen worldwide: Most crop plants have gotten shorter. No longer shoulder-high, wheat is now waist high or knee high. No longer 12 feet tall, corn is now head-high. That is the most visible part of the Borlaug legacy. And it’s why 7 billion people are eating on the same land that half a century ago could not feed half that number.This farm kid from Iowa achieved all this under difficult conditions in a hungry country: Mexico. He did it with dedication and with conventional plant breeding. He gave his seeds away freely to all who asked. He trained young people from almost every wheat-growing nation, including the U.S. and Canada, and sent them home with seeds of his most advanced research lines. That is why food production soared so quickly and global famine was averted. Borlaug’s students – widely known as Wheat Apostles – were pre-positioned and pre-programmed to make the most of his latest and most productive seeds.Norman Borlaug is an Indiana Jones of our time. He was bold and adventurous and faced down difficulty (sometimes danger) his whole life. He is a great role model for humanitarian achievement.Our Daily Bread tells the Borlaug story in lively style. It has been called The World's First Cereal Thriller. The author worked with Borlaug and recorded the behind-the-scenes dramas that have not been made public until now.

    From the "phantom pain" experienced by people who have lost their limbs to the uncanny faculty of "blindsight," Humphrey argues that raw sensations are central to all conscious states and that consciousness must have evolved, just like all other mental faculties, over time from our ancestors' bodily responses to pain and pleasure. '

    It all comes down to communication and this is one book that has no problem with telling it how it is.