is the first deep-dive investigation of a hazardous and illicit industry that has created a worldwide epidemic, ravaging communities and overwhelming and confounding government agencies that are challenged to combat it. "A whole new crop of chemicals is radically changing the recreational drug landscape," writes Ben Westhoff. "These are known as Novel Psychoactive Substances (NPS) and they include replacements for known drugs like heroin, cocaine, ecstasy, and marijuana. They are synthetic, made in a laboratory, and are much more potent than traditional drugs"--and all-too-often tragically lethal. Drugs like fentanyl, K2, and Spice--and those with arcane acronyms like 25i-NBOMe-- were all originally conceived in legitimate laboratories for proper scientific and medicinal purposes. Their formulas were then hijacked and manufactured by rogue chemists, largely in China, who change their molecular structures to stay ahead of the law, making the drugs' effects impossible to predict. Westhoff has infiltrated this shadowy world, becoming the first journalist to report from inside an illicit Chinese fentanyls lab and providing startling and original reporting on how China's vast chemical industry operates, and how the Chinese government subsidizes it. He tracks down the little-known scientists who invented these drugs and inadvertently killed thousands, as well as a mysterious drug baron who turned the law upside down in his home country of New Zealand. Poignantly, Westhoff chronicles the lives of addicted users and dealers, families of victims, law enforcement officers, and underground drug awareness organizers in the U.S. and Europe. Together they represent the shocking and riveting full anatomy of a calamity we are just beginning to understand. From its depths, as Westhoff relates, are emerging new strategies that may provide essential long-term solutions to the drug crisis that has affected so many.

    Set in Edwardian London and on the stormy coasts of Cornwall, Cape Cod, and Nova Scotia, Thunderstruck evokes the dynamism of those years when great shipping companies competed to build the biggest, fastest ocean liners, scientific advances dazzled the public with visions of a world transformed, and the rich outdid one another with ostentatious displays of wealth. Against this background, Marconi races against incredible odds and relentless skepticism to perfect his invention: the wireless, a prime catalyst for the emergence of the world we know today. Meanwhile, Crippen, “the kindest of men,” nearly commits the perfect crime. With his superb narrative skills, Erik Larson guides these parallel narratives toward a relentlessly suspenseful meeting on the waters of the North Atlantic. Along the way, he tells of a sad and tragic love affair that was described on the front pages of newspapers around the world, a chief inspector who found himself strangely sympathetic to the killer and his lover, and a driven and compelling inventor who transformed the way we communicate. Thunderstruck presents a vibrant portrait of an era of séances, science, and fog, inhabited by inventors, magicians, and Scotland Yard detectives, all presided over by the amiable and fun-loving Edward VII as the world slid inevitably toward the first great war of the twentieth century. Gripping from the first page, and rich with fascinating detail about the time, the people, and the new inventions that connect and divide us, Thunderstruck is splendid narrative history from a master of the form.

    Weight gain and obesity are driven by hormones—in everyone—and only by understanding the effects of insulin and insulin resistance can we achieve lasting weight loss.In this highly readable and provocative book, Dr. Jason Fung sets out an original, robust theory of obesity that provides startling insights into proper nutrition. In addition to his five basic steps, a set of lifelong habits that will improve your health and control your insulin levels, Dr. Fung explains how to use intermittent fasting to break the cycle of insulin resistance and reach a healthy weight—for good.

    Jewelry and valuables were left in plain sight, bodies were piled together, faces covered with cloth. Some of these cases, like the infamous Villasca, Iowa, murders, received national attention. But few people believed the crimes were related. And fewer still would realize that all of these families lived within walking distance to a train station.When celebrated baseball statistician and true crime expert Bill James first learned about these horrors, he began to investigate others that might fit the same pattern. Applying the same know-how he brings to his legendary baseball analysis, he empirically determined which crimes were committed by the same person. Then after sifting through thousands of local newspapers, court transcripts, and public records, he and his daughter Rachel made an astonishing discovery: they learned the true identity of this monstrous criminal. In turn, they uncovered one of the deadliest serial killers in America.Riveting and immersive, with writing as sharp as the cold side of an axe, The Man from the Train paints a vivid, psychologically perceptive portrait of America at the dawn of the twentieth century, when crime was regarded as a local problem, and opportunistic private detectives exploited a dysfunctional judicial system. James shows how these cultural factors enabled such an unspeakable series of crimes to occur, and his groundbreaking approach to true crime will convince skeptics, amaze aficionados, and change the way we view criminal history.

    In 1828, when New York City purchased this narrow, two-mile-long island in the East River, it was called Blackwell’s Island. There, over the next hundred years, the city would send its insane, indigent, sick, and criminal. Told through the gripping voices of Blackwell’s inhabitants, as well as the period’s city officials, reformers, and journalists (including the famous Nellie Bly), Stacy Horn has crafted a compelling and chilling narrative.  Damnation Island recreates what daily life was like on the island, what politics shaped it, and what constituted charity and therapy in the nineteenth century. Throughout the book, we return to the extraordinary Blackwell’s missionary Reverend French, champion of the forgotten, as he ministers to these inmates, battles the bureaucratic mazes of the Corrections Department and a corrupt City Hall, testifies at salacious trials, and in his diary wonders about man’s inhumanity to man.   For history fans, and for anyone interested in the ways we care for the least fortunate among us, Damnation Island is an eye-opening look at a closed and secretive world. With a tale that is exceedingly relevant today, Horn shows us how far we’ve come—and how much work still remains.

    But that November 1, her life was shattered when her roommate, British student Meredith Kercher, was murdered in their apartment. Five days later, Amanda was taken into custody and charged by the Italian police; her arrest and the subsequent investigation ignited an international media firestorm. Overnight, this ordinary young American student became the subject of intense scrutiny, forced to endure a barrage of innuendo and speculation. Two years later, after an extremely controversial trial, Amanda was convicted and imprisoned. But in 2011 an appeals court overturned her conviction and vacated the charges. Free at last, she immediately returned home to the U.S., where she has remained silent, until now.

    Missoula, Montana, is a typical college town, with a highly regarded state university, bucolic surroundings, a lively social scene, and an excellent football team — the Grizzlies — with a rabid fan base. The Department of Justice investigated 350 sexual assaults reported to the Missoula police between January 2008 and May 2012. Few of these assaults were properly handled by either the university or local authorities. In this, Missoula is also typical. A DOJ report released in December of 2014 estimates 110,000 women between the ages of eighteen and twenty-four are raped each year. Krakauer’s devastating narrative of what happened in Missoula makes clear why rape is so prevalent on American campuses, and why rape victims are so reluctant to report assault. Acquaintance rape is a crime like no other. Unlike burglary or embezzlement or any other felony, the victim often comes under more suspicion than the alleged perpetrator. This is especially true if the victim is sexually active; if she had been drinking prior to the assault — and if the man she accuses plays on a popular sports team. The vanishingly small but highly publicized incidents of false accusations are often used to dismiss her claims in the press. If the case goes to trial, the woman’s entire personal life becomes fair game for defense attorneys. This brutal reality goes a long way towards explaining why acquaintance rape is the most underreported crime in America. In addition to physical trauma, its victims often suffer devastating psychological damage that leads to feelings of shame, emotional paralysis and stigmatization. PTSD rates for rape victims are estimated to be 50%, higher than soldiers returning from war. In Missoula, Krakauer chronicles the searing experiences of several women in Missoula — the nights when they were raped; their fear and self-doubt in the aftermath; the way they were treated by the police, prosecutors, defense attorneys; the public vilification and private anguish; their bravery in pushing forward and what it cost them. Some of them went to the police. Some declined to go to the police, or to press charges, but sought redress from the university, which has its own, non-criminal judicial process when a student is accused of rape. In two cases the police agreed to press charges and the district attorney agreed to prosecute. One case led to a conviction; one to an acquittal. Those women courageous enough to press charges or to speak publicly about their experiences were attacked in the media, on Grizzly football fan sites, and/or to their faces. The university expelled three of the accused rapists, but one was reinstated by state officials in a secret proceeding. One district attorney testified for an alleged rapist at his university hearing. She later left the prosecutor’s office and successfully defended the Grizzlies’ star quarterback in his rape trial. The horror of being raped, in each woman’s case, was magnified by the mechanics of the justice system and the reaction of the community. Krakauer’s dispassionate, carefully documented account of what these women endured cuts through the abstract ideological debate about campus rape. College-age women are not raped because they are promiscuous, or drunk, or send mixed signals, or feel guilty about casual sex, or seek attention. They are the victims of a terrible crime and deserving of compassion from society and fairness from a justice system that is clearly broken.

    But he was alive and trapped inside his own body for ten years.In January 1988 Martin Pistorius, aged twelve, fell inexplicably sick. First he lost his voice and stopped eating. Then he slept constantly and shunned human contact. Doctors were mystified. Within eighteen months he was mute and wheelchair-bound. Martin's parents were told an unknown degenerative disease left him with the mind of a baby and less than two years to live.Martin was moved to care centers for severely disabled children. The stress and heartache shook his parents’ marriage and their family to the core. Their boy was gone. Or so they thought.Ghost Boy is the heart-wrenching story of one boy’s return to life through the power of love and faith. In these pages, readers see a parent’s resilience, the consequences of misdiagnosis, abuse at the hands of cruel caretakers, and the unthinkable duration of Martin’s mental alertness betrayed by his lifeless body.We also see a life reclaimed—a business created, a new love kindled—all from a wheelchair. Martin's emergence from his own darkness invites us to celebrate our own lives and fight for a better life for others.

    Spanning decades and continents, subjects range from the opulent Hope Diamond to the humble Busy Stoop chair.They're lurking in museums, graveyards, and private homes around the world. Their stories have inspired countless horror movies, reality TV shows, campfire tales, books, and even chain emails. They're cursed objects, and in order to unleash a wave of misfortune, all they need...is you. As a culture, we can't seem to get enough of cursed objects. But never before have the true stories of these infamous real-life items been compiled into a fascinating and chilling volume.Entries include: • Annabelle the Doll, a Raggedy Ann doll which inspired the acclaimed horror franchise The Conjuring • The Tomb of Tutankhamen, the discovery of which kicked-started media hysteria over a rumored "Curse of the Pharaohs" • The Ring of Silvianus, a Roman artifact believed to have inspired J. R. R. Tolkien's The Hobbit • The Hope Diamond, which was owned by kings and inspired the Heart of the Ocean in James Cameron's Titanic • The Dybbuk Box, which was sold on eBay and inspired the horror film The PossessionWhether you believe in curses or not, the often tragic and always bizarre stories behind these objects will fascinate you. Many of them have intersected with some of the most notable events and people in history. But beyond Hollywood and beyond the hysteria, author J. W. Ocker suggests that cursed objects are simply objects which have been witness to great human tragedy, and thereafter operate as mechanisms for remembering and retelling those stories. Cursed Objects will be equally appealing to true believers as well as history buffs, horror fans, and anyone who loves a good spine-tingling tale.

    His assailant ran down the street, jumped into an SUV, and vanished, hoping to join the vast majority of killers in American cities who are never arrested for their crimes. But as soon as the case was assigned to Detective John Skaggs, the odds shifted. Here is the kaleidoscopic story of the quintessential American murder--one young black man slaying another--and a determined crew of detectives whose creed was to pursue justice at all costs for its forgotten victims. Ghettoside is a fast-paced narrative of a devastating crime, an intimate portrait of detectives and a community bonded in tragedy, and a surprising new lens into the great subject of murder in America--why it happens and how the plague of killings might yet be stopped.

    See ISBN 9780465094646History is full of strange animal stories invented by the brightest and most influential, from Aristotle to Disney. But when it comes to understanding animals, we’ve got a long way to go.Whether we’re watching a viral video of romping baby pandas or looking at a picture of penguins ‘holding hands’, we often project our own values – innocence, abstinence, hard work – onto animals. So you’ve probably never considered that moose get drunk and that penguins are notorious cheats.In The Unexpected Truth About Animals Zoologist Lucy unravels many such myths – that eels are born from sand, that swallows hibernate under water, and that bears gave birth to formless lumps that are licked into shape by their mothers – to show that the stories we create reveal as much about us as they do about the animals.Astonishing, illuminating and laugh-out-loud funny.

    Now, in The New Science of the Human Past, Reich describes just how the human genome provides not only all the information that a fertilized human egg needs to develop but also contains within it the history of our species. He delineates how the Genomic Revolution and ancient DNA are transforming our understanding of our own lineage as modern humans; how genomics deconstructs the idea that there are no biologically meaningful differences among human populations (though without adherence to pernicious racist hierarchies); and how DNA studies reveal the deep history of human inequality--among different populations, between the sexes, and among individuals within a population.

    Your head hurts. You're mildly annoyed as you get the kids ready for school and dress for work yourself. Meanwhile, an epic war is being fought, just below your skin. Millions are fighting and dying for you to be able to complain as you head out the door.So what, exactly, is your immune system?Second only to the human brain in its complexity, it is one of the oldest and most critical facets of life on Earth. Without it, you would die within days. In Immune, Philipp Dettmer, the brains behind the most popular science channel on YouTube, takes readers on a journey through the fortress of the human body and its defenses. There is a constant battle of staggering scale raging within us, full of stories of invasion, strategy, defeat, and noble self-sacrifice. In fact, in the time you've been reading this, your immune system has probably identified and eradicated a cancer cell that started to grow in your body.Each chapter delves into an element of the immune system, including defenses like antibodies and inflammation as well as threats like bacteria, allergies, and cancer, as Dettmer reveals why boosting your immune system is actually nonsense, how parasites sneak their way past your body's defenses, how viruses work, and what goes on in your wounds when you cut yourself.Enlivened by engaging graphics and immersive descriptions, Immune turns one of the most intricate, interconnected, and confusing subjects—immunology—into a gripping adventure through an astonishing alien landscape. Immune is a vital and remarkably fun crash course in what is arguably, and increasingly, the most important system in the body.

    With humor and insight, Melissa Mohr takes readers on a journey to discover how "swearing" has come to include both testifying with your hand on the Bible and calling someone a *#$&!* when they cut you off on the highway. She explores obscenities in ancient Rome and unearths the history of religious oaths in the Middle Ages, when swearing (or not swearing) an oath was often a matter of life and death. Holy Sh*t also explains the advancement of civility and corresponding censorship of language in the 18th century, considers the rise of racial slurs after World War II, examines the physiological effects of swearing and answers a question that preoccupies the FCC, the US Senate, and anyone who has recently overheard little kids at a playground: are we swearing more now than people did in the past?A gem of lexicography and cultural history, Holy Sh*t is a serious exploration of obscenity.

    Crammed into old houses and hotels, abandoned prisons and empty hospitals, the spirits that linger continue to capture our collective imagination, but why? His own fascination piqued by a house hunt in Los Angeles that revealed derelict foreclosures and "zombie homes," Dickey embarks on a journey across the continental United States to decode and unpack the American history repressed in our most famous haunted places. Some have established reputations as "the most haunted mansion in America," or "the most haunted prison"; others, like the haunted Indian burial grounds in West Virginia, evoke memories from the past our collective nation tries to forget.            With boundless curiosity, Dickey conjures the dead by focusing on questions of the living—how do we, the living, deal with stories about ghosts, and how do we inhabit and move through spaces that have been deemed, for whatever reason, haunted? Paying attention not only to the true facts behind a ghost story, but also to the ways in which changes to those facts are made—and why those changes are made—Dickey paints a version of American history left out of the textbooks, one of things left undone, crimes left unsolved. Spellbinding, scary, and wickedly insightful, Ghostland discovers the past we're most afraid to speak of aloud in the bright light of day is the same past that tends to linger in the ghost stories we whisper in the dark.From the Hardcover edition.