Lieberman illuminates how these ongoing changes have brought many benefits, but also have created novel conditions to which our bodies are not entirely adapted, resulting in a growing incidence of obesity and new but avoidable diseases, including type-2 diabetes. He proposes that many of these chronic illnesses persist and in some cases are intensifying because of "dysevolution," a pernicious dynamic whereby only the symptoms rather than the causes of these maladies are treated. And finally—provocatively—he advocates the use of evolutionary information to help nudge, push, and sometimes oblige us to create a more salubrious environment.(With charts and line drawings throughout.)From the Hardcover edition.

    Just a half century ago, this idea was revolutionary. In April 1953, James Watson and Francis Crick published in Nature their groundbreaking work revealing the double helix structure of DNA. While this discovery received wide attention from both mainstream media and the academic community, it was just one part of the bigger story in this history of molecular biology. By the mid-1950s, the scientific community confirmed that genes were indeed comprised of DNA; they just needed to crack the genetic code—and the race was on. Life’s Greatest Secret is the full and rich history of this challenge and the characters—many of whom were not biologists—whose work contributed to this grand scientific endeavor: mathematician and father of cybernetics Norbert Wiener, physicist Erwin Schrödinger, information theorist Claude Shannon, and biologists Jacques Monod and Marshall Nirenberg.In Life’s Greatest Secret, science historian and zoologist Matthew Cobb shows that the race to crack the genetic code was mostly a matter of craft—individuals or small groups struggling with ideas and concepts as much as they were with facts, trying to find the right experiment to answer the right questions, even if they didn’t know what the questions were, and finding that, even when the most definitive answer served mostly to reveal more ignorance, whether in 1953, with Watson and Crick, or in 1961, when Nirenberg and Matthaei showed how DNA codes for specific amino acids, and again and again thereafter, or in 2000, with the first publication of a human genome. Each discovery was a leap forward in our understanding of the natural world and our place within in, akin to the discoveries of Galileo and Einstein in the realm of physics, or the publication of Darwin’s On the Origin of Species. And each served to show how much bigger the problem was that anyone had previously imagined, a trend that continues, as Cobb shows, even today, whether we are discussing gene regulation, epigenetics, or GMOs.Life’s Greatest Secret is a story of ideas and of experimentation, of ingenuity, insight, and dead-ends, in the hunt to make the greatest discovery of twentieth century biology. Ultimately, though, this is a story of humans exploring what it is that makes us human.

    We know they make your eyes blue, your hair curly or your nose straight. The media tells us that our genes control the risk of cancer, heart disease, alcoholism or Alzheimer's. The cost of DNA sequencing has plummeted from billions of pounds to a few hundred, and gene-based advances in medicine hold huge promise.So we've all heard of genes, but how do they actually work?According to legend, Ernest Hemingway was once given a six-toed cat by an old sea captain, and her distinctive descendants still roam the writer's Florida estate today. Scientists now know that the fault driving this profusion of digits lies in a tiny genetic control switch, miles away (in molecular terms) from the gene that 'makes' toes. And it's the same mistake that gives rise to multi-toed humans too.There are 2.2 metres of DNA inside every one of your cells, encoding roughly 20,000 genes. These are the 'recipes' that tell our cells how to make the building blocks of life, along with myriad control switches ensuring they're turned on and off at the right time and in the right place. But rather than a static string of genetic code, this is a dynamic, writhing biological library. And figuring out how it all works – how your genes make you, you – is a major challenge for researchers around the world.Drawing on stories ranging from six-toed cats and stickleback hips to wobbly worms and zombie genes, geneticist Kat Arney explores the how our genes work, creating a companion reader to the book of life itself.

    But for the past thirty-five years of his professional life, he has also been active as an investigator of the paranormal, occult, and supernatural claims that have impressed the thinking of the public for a generation: ESP, psychokinesis, psychic detectives, levitation, psychic surgery, UFOs, dowsing, astrology, and many others. Those of us unable to discriminate between geniune scientific research and the pseudoscientific nonsense that has resulted in fantastic theories and fancies have long needed James Randi and Flim-Flam!In this book, Randi explores and exposes what he believes to be the outrageous deception that has been promoted widely in the media. Unafraid to call researchers to account for their failures and impostures, Randi tells us that we have been badly served by scientists who have failed to follow the procedures required by their training and traditions. Here he shows us how what he views as sloppy research has been followed by rationalizations of evident failures, and we see these errors and misrepresentations clearly pointed out. Mr. Randi provides us with a compelling and convincing document that will certainly startle and enlighten all who read it.

    But are there limits to what we can discover about our physical universe?In this very personal journey to the edges of knowledge, Marcus du Sautoy investigates how leading experts in fields from quantum physics and cosmology, to sensory perception and neuroscience, have articulated the current lie of the land. In doing so, he travels to the very boundaries of understanding, questioning contradictory stories and consulting cutting edge data.Is it possible that we will one day know everything? Or are there fields of research that will always lie beyond the bounds of human comprehension? And if so, how do we cope with living in a universe where there are things that will forever transcend our understanding?In What We Cannot Know, Marcus du Sautoy leads us on a thought-provoking expedition to the furthest reaches of modern science. Prepare to be taken to the edge of knowledge to find out if there’s anything we truly cannot know.

    Why do living things and physical phenomena take the forms they do? Analyzing the mathematical and physical aspects of biological processes, this historic work, first published in 1917, has become renowned as well for the poetry of is descriptions.

    Craig Venter became the first to successfully create synthetic life putting humankind at the threshold of the most important and exciting phase of biological research, one that will enable us to actually write the genetic code for designing new species to help us adapt and evolve for long-term survival. The science of synthetic genomics will have a profound impact on human existence, including chemical and energy generation, health, clean water and food production, environmental control, and possibly even our evolution. In "Life at the Speed of Light," Venter presents a fascinating and authoritative study of this emerging field from the inside detailing its origins, current challenges and controversies, and projected effects on our lives. This scientific frontier provides an opportunity to ponder anew the age-old question What is life? and examine what we really mean by playing God. " Life at the Speed of Light "is a landmark work, written by a visionary at the dawn of a new era of biological engineering."

    The book analyzes how differences could affect the plant, animal and human life on planet Earth.

    One of the most important achievements of the past millennium, it did for biology what Galileo did for astronomy: made it into a single science rather than a collection of unrelated facts. Important though Origin remains, its examples and intricate Victorian prose are now a century and a half old. They are ripe for renewal and reaffirmation. Writing as "Darwin's ghost," eminent geneticist Steve Jones updates this seminal work—and restates evolution's case for the 21st century.Jones is a writer of engaging wit and dazzling erudition and has been called "the British Carl Sagan." Using modern examples—the AIDS virus, the puzzles of sexual selection, the physiology and psychology of pets, and the unparalleled genetic success of our own species—he shows the power and immediacy of Darwin's great argument and makes us appreciate how it makes life make sense. Eye-opening and entertaining, filled with astonishing facts, amusing anecdotes, and the very latest research, Darwin's Ghost is contemporary science writing at its very best.

    With personal anecdotes, a well-written narrative, and clear examples, Human Natures is a major work of synthesis and scholarship as well as a valuable primer on genetics and evolution that makes complex scientific concepts accessible to lay readers.

    Structured around a plane journey that sees encounters with substances from water and glue to coffee and wine, Liquid Rules shows how these liquids can bring death and destruction as well as wonder and fascination.From László Bíró's revolutionary pen and Abraham Gesner's kerosene to cutting-edge research on self-repairing roads and liquid computers, Miodownik uses his winning formula of scientific storytelling to bring the everyday to life. He reveals why liquids can flow up a tree but down a hill, why oil is sticky, how waves can travel so far, and how to make the perfect cup of tea. Here are the secret lives of substances.

    One sought to discover a new planet. Another—an adventuresome female astronomer—fought to prove that science was not anathema to femininity. And a young, megalomaniacal inventor, with the tabloid press fast on his heels, sought to test his scientific bona fides and light the world through his revelations. David Baron brings to three-dimensional life these three competitors—James Craig Watson, Maria Mitchell, and Thomas Edison—and thrillingly re-creates the fierce jockeying of nineteenth-century American astronomy. With spellbinding accounts of train robberies and Indian skirmishes, the mythologized age of the last days of the Wild West comes alive as never before. A magnificent portrayal of America’s dawn as a scientific superpower, American Eclipse depicts a young nation that looked to the skies to reveal its towering ambition and expose its latent genius.

    Dark matter. These strange and invisible substances don't just sound mysterious: their unexpected appearance in the cosmic census is upending long-held notions about the nature of the Universe. Astronomers have long known that the Universe is expanding, but everything they could see indicated that gravity should be slowing this spread. Instead, it appears that the Universe is accelerating its expansion and that something stronger than gravity--dark energy--is at work. In Einstein's Telescope Evalyn Gates, a University of Chicago astrophysicist, transports us to the edge of contemporary science to explore the revolutionary tool that unlocks the secrets of these little-understood cosmic constituents. Based on Einstein's theory of general relativity, gravitational lensing, or "Einstein's Telescope," is enabling new discoveries that are taking us toward the next revolution in scientific thinking--one that may change forever our notions of where the Universe came from and where it is going.

    From the tenth to the fifteenth centuries the earth experienced a rise in surface temperature that changed climate worldwide—a preview of today's global warming. In some areas, including Western Europe, longer summers brought bountiful harvests and population growth that led to cultural flowering. In the Arctic, Inuit and Norse sailors made cultural connections across thousands of miles as they traded precious iron goods. Polynesian sailors, riding new wind patterns, were able to settle the remotest islands on earth. But in many parts of the world, the warm centuries brought drought and famine. Elaborate societies in western and central America collapsed, and the vast building complexes of Chaco Canyon and the Mayan Yucatan were left empty.As he did in his bestselling The Little Ice Age, anthropologist and historian Brian Fagan reveals how subtle changes in the environment had far-reaching effects on human life, in a narrative that sweeps from the Arctic ice cap to the Sahara to the Indian Ocean. The history of the Great Warming of a half millennium ago suggests that we may yet be underestimating the power of climate change to disrupt our lives today—and our vulnerability to drought, writes Fagan, is the "silent elephant in the room."Learn more at www.brianfagan.com.Brian Fagan discusses The Great Warming on The Daily Show with John Stewart.PRAISE for The Great Warming:"This is not only World History at its best, sweeping across all of humankind with a coherent vision, but also a feat of imagination and massive research. If Fagan has given the medieval period throughout the globe a new dimension, he has at the same time issued an irrefutable warning about climate change that is deeply troubling."—Theodore Rabb, author of The Last Days of the Renaissance"Climate has been making history for a very long time, though historians have rarely paid much attention to it. But as it turns out, a few less inches of rain, a change in temperature of just a degree or two can make all the difference in how human events unfold. The Great Warming demonstrates that although human beings make history, they very definitely do not make it under circumstances of their own choosing.”—Ted Steinberg, author of Down to Earth: Nature’s Role in American History and American Green: The Obsessive Quest for the Perfect Lawn

    From tales of vegetarian piranha fish and voiceless dogs to the scientific search for the genes that threaten to destroy the cheetah, Quammen captures the natural world with precision. A distinguished natural science essayist, Quammen’s reporting is masterful and thought provoking and his curiosity and fascination with the world of living things is infectious.