. . alive and fascinating and provocative on every page."—Oliver Sacks, M.D.Porter's charting of the history of medicine affords readers the opportunity as never before to assess its culture and science and its costs and benefits to humankind. "A splendid and thoroughly engrossing book."--"L.A. Times." of illustrations.

    Theologians quickly labeled Charles Darwin the most dangerous man in England, and, as the Saturday Review noted, the uproar over the book quickly "passed beyond the bounds of the study and lecture-room into the drawing-room and the public street." Yet, after reading it, Darwin's friend and colleague T. H. Huxley had a different reaction: "How extremely stupid not to have thought of that."Based largely on Darwin's experience as a naturalist while on a five-year voyage aboard H.M.S. Beagle, The Origin of Species set forth a theory of evolution and natural selection that challenged contemporary beliefs about divine providence and the immutability of species. A landmark contribution to philosophical and scientific thought, this edition also includes an introductory historical sketch and a glossary Darwin later added to the original text.Charles Darwin grew up considered, by his own account, "a very ordinary boy, rather below the common standard of intellect." A quirk of fate kept him from the career his father had deemed appropriate--that of a country parson--when a botanist recommended Darwin for an appointment as a naturalist aboard H.M.S. Beagle from 1831 to 1836. Darwin is also the author of the five-volume work Zoology of the Voyage of the Beagle (1839) and The Descent of Man (1871).From the Trade Paperback edition.

    Describes how fractals were discovered, explains their unique properties, and discusses the mathematical foundation of fractals.

    Accompanying this unique perspective on our ever-evolving view of the universe are some of the most visually dramatic illustrations you'll ever see. Short, lucid articles focus on everything from the speculations of the ancient Greeks to today's Nobel Prize winners, from Ptolemy's theory of an Earth-centered universe to the first steps on the moon, and from the dawning of the concept of zero to the cloning of Dolly the sheep. Biology, physics, astronomy, medicine, and mathematics: the breakthroughs in every field are all here and celebrated, in the first truly accessible, fully illustrated story of science.

    This text has invited more than 4 million students into the study of this dynamic and essential discipline.The authors have restructured each chapter around a conceptual framework of five or six big ideas. An Overview draws students in and sets the stage for the rest of the chapter, each numbered Concept Head announces the beginning of a new concept, and Concept Check questions at the end of each chapter encourage students to assess their mastery of a given concept. New Inquiry Figures focus students on the experimental process, and new Research Method Figures illustrate important techniques in biology. Each chapter ends with a Scientific Inquiry Question that asks students to apply scientific investigation skills to the content of the chapter.

    Some of these drugs are truly transformative, offering major improvements in how long patients live or how they feel--but what is often missing from the popular narrative is that, far too often, these new drugs have marginal or minimal benefits. Some are even harmful. In Malignant, hematologist-oncologist Dr. Vinayak K. Prasad writes about the many sobering examples of how patients are too often failed by cancer policy and by how oncology is practiced. Throughout this work, Prasad illuminates deceptive practices which- promote novel cancer therapies long before credible data are available to support such treatment; and- exaggerate the potential benefits of new therapies, many of which cost thousands and in some cases hundreds of thousands of dollars.Prasad then critiques the financial conflicts of interest that pervade the oncology field, the pharmaceutical industry, and the US Food and Drug administration.This is a book about how the actions of human beings--our policies, our standards of evidence, and our drug regulation--incentivize the pursuit of marginal or unproven therapies at lofty and unsustainable prices. Prasad takes us through how cancer trials are conducted, how drugs come to market, and how pricing decisions are made, asking how we can ensure that more cancer drugs deliver both greater benefit and a lower price. Ultimately, Prasad says,- more cancer clinical trials should measure outcomes that actually matter to people with cancer;- patients on those trials should look more like actual global citizens;- we need drug regulators to raise, not perpetually lower, the bar for approval; and- we need unbiased patient advocates and experts.This well-written, opinionated, and engaging book explains what we can do differently to make serious and sustained progress against cancer--and how we can avoid repeating the policy and practice mistakes of the past.

    An eclectic collection of the year's best reportage, The Best American Crime Reporting 2007 brings together the murderers and muscle men, the masterminds, and the mysteries and missteps that make for brilliant stories, told by the aces of the true crime genre. This latest addition to the highly acclaimed series features guest editor Linda Fairstein, the bestselling crime novelist and former chief prosecutor of the Manhattan District Attorney's Office's pioneering Special Victims' Unit.The loved ones / Tom Junod --The inside job / Neil Swidey --The talented Dr. Krist / Steve Fennessy --The case of the killer priest / Sean Flynn --Double blind / Matthew Teague --The school / C.J. Chivers --A kiss before dying / Pamela Colloff --The devil in David Berkowitz / Steve Fishman --The man who loves books too much / Allison Hoover Bartlett --Dirty old women / Ariel Levy --Who killed Ellen Andros? / Dan P. Lee --Fatal connection / David Bernstein --Last seen on September 10th / Mark Fass --My roommate, the diamond thief / Brian Boucher --The monster of Florence / Douglas Preston

    The theme of Heisenberg's exposition is that words and concepts familiar in daily life can lose their meaning in the world of relativity and quantum physics. This in turn has profound philosophical implications for the nature of reality and for our total world view.

    Like a Wu Li Master who would teach us wonder for the falling petal before speaking of gravity, Zukav writes in beautifully clear language—with no mathematical equations—opening our minds to the exciting new theories that are beginning to embrace the ultimate nature of our universe...Quantum mechanics, relativity, and beyond to the Einstein-Podolsky-Rosen effect and Bell's theorem.At an Esalen Institute meeting in 1976, tai chi master Al Huang said that the Chinese word for physics is Wu Li, "patterns of organic energy." Journalist Gary Zukav and the others present developed the idea of physics as the dance of the Wu Li Masters--the teachers of physical essence. Zukav explains the concept further: The Wu Li Master dances with his student. The Wu Li Master does not teach, but the student learns. The Wu Li Master always begins at the center, the heart of the matter.... This book deals not with knowledge, which is always past tense anyway, but with imagination, which is physics come alive, which is Wu Li.... Most people believe that physicists are explaining the world. Some physicists even believe that, but the Wu Li Masters know that they are only dancing with it. The "new physics" of Zukav's 1979 book comprises quantum theory, particle physics, and relativity. Even as these theories age they haven't percolated all that far into the collective consciousness; they're too far removed from mundane human experience not to need introduction. The Dancing Wu Li Masters remains an engaging, accessible way to meet the most profound and mind-altering insights of 20th-century science. --Mary Ellen Curtin

    

    Most scientists don't care how they are perceived, but in our media-dominated age, style points count.Enter Randy Olson.  Fifteen years ago, Olson bid farewell to the science world and shipped off to Hollywood ready to change the world. With films like Flock of Dodos: The Evolution-Intelligent Design Circus (Tribeca '06, Showtime) and Sizzle: A Global Warming Comedy (Outfest '08), he has tried to bridge the cultural divide that has too often left science on the outside looking in.Now, in his first book, Olson, with a Harvard Ph.D. and formerly a tenured professor of marine biology at the University of New Hampshire, recounts the lessons from his own hilarious-and at times humiliating-evolution from science professor to Hollywood filmmaker.  In Don't Be Such a Scientist, he shares the secrets of talking substance in an age of style. The key, he argues, is to stay true to the facts while tapping into something more primordial, more irrational, and ultimately more human.In a book enlivened by a profane acting teacher who made Olson realize that "nobody wants to watch you think," he offers up serious insights and poignant stories. You'll laugh, you may cry, and as a communicator you'll certainly learn the importance of not only knowing how to fulfill, but also how to arouse.

    “Essays are restless literature, trying to find out how things fit together, how we can think about two things at once, how the personal and the public can inform each other, how two overtly dissimilar things share a secret kinship,” contends Rebecca Solnit in her introduction. From lost languages and extinct species to life-affirming cosmologies and literary myths that offer cold comfort, the personal and the public collide in The Best American Essays 2019. This searching, necessary collection grapples with what has preoccupied us in the past year—sexual politics, race, violence, invasive technologies—and yet, in reading for the book, Solnit also found “how discovery can be a deep pleasure.”  The Best American Essays 2019 includes Michelle Alexander, Jabari Asim, Alexander Chee, Masha Gessen, Jean Guerrero, Elizabeth Kolbert, Terese Marie Mailhot, Jia Tolentino, and others.

    Many people think of microbes as germs to be eradicated, but those that live with us—the microbiome—build our bodies, protect our health, shape our identities, and grant us incredible abilities. In this astonishing book, Ed Yong takes us on a grand tour through our microbial partners, and introduces us to the scientists on the front lines of discovery. Yong, whose humor is as evident as his erudition, prompts us to look at ourselves and our animal companions in a new light—less as individuals and more as the interconnected, interdependent multitudes we assuredly are. The microbes in our bodies are part of our immune systems and protect us from disease. Those in cows and termites digest the plants they eat. In the deep oceans, mysterious creatures without mouths or guts depend on microbes for all their energy. Bacteria provide squids with invisibility cloaks, help beetles to bring down forests, and allow worms to cause diseases that afflict millions of people. I Contain Multitudes is the story of these extraordinary partnerships, between the creatures we are familiar with and those we are not. It reveals how we humans are disrupting these partnerships and how we might manipulate them for our own good. It will change both our view of nature and our sense of where we belong in it.

    The science of complexity studies how single elements, such as a species or a stock, spontaneously organize into complicated structures like ecosystems and economies; stars become galaxies, and snowflakes avalanches almost as if these systems were obeying a hidden yearning for order. Drawing from diverse fields, scientific luminaries such as Nobel Laureates Murray Gell-Mann and Kenneth Arrow are studying complexity at a think tank called The Santa Fe Institute. The revolutionary new discoveries researchers have made there could change the face of every science from biology to cosmology to economics. M. Mitchell Waldrop's groundbreaking bestseller takes readers into the hearts and minds of these scientists to tell the story behind this scientific revolution as it unfolds.

    Wilson’s view? Recording observations in the field is an indispensable scientific skill, but researchers are not generally willing to share their personal records with others. Here, for the first time, are reproductions of actual pages from notebooks. And in essays abounding with fascinating anecdotes, the authors reflect on the contexts in which the notes were taken.Covering disciplines as diverse as ornithology, entomology, ecology, paleontology, anthropology, botany, and animal behavior, Field Notes offers specific examples that professional naturalists can emulate to fine-tune their own field methods, along with practical advice that amateur naturalists and students can use to document their adventures.