As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his co-discovery of the structure of DNA. She and her collaborators turned ​a curiosity ​of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020.

    The family are Sikhs. Today. In a few years they will be Jewish. Cheryl’s name is Harbhajan. Today. But in a few years she will be Crystal. By the time she turns nine, Cheryl has had at least six assumed identities. She has lived on five continents, fleeing the specter of Interpol and law enforcement. Her father, a master financial criminal, or so she believes, uproots the family at the slightest sign of suspicion.   Despite the strange circumstances, Diamond’s life as a young child is mostly joyful and exciting, her family of five a tiny, happy circle unto themselves. Even as she learn how to forge identity papers and fix a car with chicken wire, she somehow becomes a near-Olympic-level athlete and then an international teenage model. She even publishes a book about it. As she grows older, though, things get darker. Her identity is burned again and again, leaving her with no past, no proof even that she exists, and her family—the only people she has in the world—begins to unravel. Love and trust turn to fear and violence. Secrets are revealed, and she is betrayed by those on whom she relies most.   Slowly, Diamond begins to realize that her life itself might be a big con. Surviving would require her to escape, and we root for this determined woman as she unlearns all the rules of her family. Cinematic and witty, Nowhere Girl is an impossible-to-believe true story of self-discovery and triumph.

    Though imperfect in every way, her dysfunctional childhood was as beautiful as it was strange, and as nurturing as it was difficult. At the age of five, Brandi contracted bacterial meningitis, which almost took her life, leaving an indelible mark on her formative years and altering her journey into young adulthood.As an openly gay teenager, Brandi grappled with the tension between her sexuality and her faith when her pastor publicly refused to baptize her on the day of the ceremony. Shockingly, her small town rallied around Brandi in support and set her on a path to salvation where the rest of the misfits and rejects find it: through twisted, joyful, weird, and wonderful music.In Broken Horses, Brandi Carlile takes listeners through the events of her life that shaped her very raw art - from her start at a local singing competition where she performed Elton John’s “Honky Cat” in a bedazzled white polyester suit, to her first break opening for Dave Matthews Band, to many sleepless tours over 15 years and six studio albums, all while raising two children with her wife, Catherine Shepherd. This hard-won success led her to collaborations with personal heroes like Elton John, Dolly Parton, Mavis Staples, Pearl Jam, Tanya Tucker, and Joni Mitchell, as well as her peers in the supergroup The Highwomen, and ultimately to the Grammy stage, where she converted millions of viewers into instant fans.Evocative and piercingly honest, Broken Horses is at once an examination of faith through the eyes of a person rejected by the church’s basic tenets and a meditation on the moments and lyrics that have shaped the life of a creative mind, a brilliant artist, and a genuine empath on a mission to give back.

    But in The Night the Lights Went Out, he finds himself far out of his depths. On the night of the 2018 Deadspin Awards, he suffered a mysterious fall that caused him to smash his head so hard on a cement floor that he cracked his skull in three places and suffered a catastrophic brain hemorrhage. For two weeks, he remained in a coma. The world was gone to him, and him to it.In his long recovery from his injury, including understanding what his family and friends went through as he lay there dying, coming to terms with his now permanent disabilities, and trying to find some lesson in this cosmic accident, he leaned on the one sure thing that he knows and that didn't leave him--his writing.Drew takes a deep dive into what it meant to be a bystander to his own death and figuring out who this new Drew is: a Drew that doesn't walk as well, doesn't taste or smell or see or hear as well, and a Drew that is often failing as a husband and a father as he bounces between grumpiness, irritability, and existential fury. But what's a good comeback story without heartbreak? Eager to get back what he lost, Drew experiences an awakening of a whole other kind in this incredibly funny, medically illuminating, and heartfelt memoir.

    The ultimate DC outsider, she joined the elite team who accompanied the president wherever he went, recorder and mic in hand. On whirlwind trips across time zones, Beck forged friendships with a tight group of fellow travelers--young men and women who, like her, left their real lives behind to hop aboard Air Force One in service of the president. But as she learned the ropes of protocol, Beck became romantically entangled with a consummate DC insider, and suddenly, the political became all too personal. Set against the backdrop of a White House full of glamour, drama, and intrigue, this is the story of a young woman making unlikely friendships, getting her heart broken, learning what truly matters, and discovering her voice in the process.

    Powerful and unforgettable, In Pieces is an inspiring account of life as a woman in the second half of the twentieth century.

    One day, Lori Gottlieb is a therapist who helps patients in her Los Angeles practice. The next, a crisis causes her world to come crashing down. Enter Wendell, the quirky but seasoned therapist in whose office she suddenly lands. With his balding head, cardigan, and khakis, he seems to have come straight from Therapist Central Casting. Yet he will turn out to be anything but. As Gottlieb explores the inner chambers of her patients' lives -- a self-absorbed Hollywood producer, a young newlywed diagnosed with a terminal illness, a senior citizen threatening to end her life on her birthday if nothing gets better, and a twenty-something who can't stop hooking up with the wrong guys -- she finds that the questions they are struggling with are the very ones she is now bringing to Wendell. With startling wisdom and humor, Gottlieb invites us into her world as both clinician and patient, examining the truths and fictions we tell ourselves and others as we teeter on the tightrope between love and desire, meaning and mortality, guilt and redemption, terror and courage, hope and change.Maybe You Should Talk to Someone is revolutionary in its candor, offering a deeply personal yet universal tour of our hearts and minds and providing the rarest of gifts: a boldly revealing portrait of what it means to be human, and a disarmingly funny and illuminating account of our own mysterious lives and our power to transform them.

    How could she help these girls if she couldn't even be honest with herself and face her own demons? A fitful night led to pages and pages of scribbled notes with two clear words at the top: Me too.Tarana Burke is the founder and activist behind the largest social movement of the twentieth and twenty-first centuries, the me too movement, but first she had to find the strength to say me too herself. Unbound is the story of how she came to those two words, after a childhood growing up in the Bronx with a loving mother that took a terrible turn when she was sexual assaulted. She became withdrawn and her self split: there was the Tarana that was a good student, model kid, and eager to please young girl, and then there was the Tarana that she hid from everyone else, the one she believed to be bad. The one that would take all the love in her life away if she revealed.Tarana's debut memoir explores how to piece back together our fractured selves. How to not just bring the me too movement back to empathy, but how to empathize with our past selves, with out bad selves, and how to begin to love ourselves unabashedly. Healing starts with empowerment, and to Tarana empowerment starts with empathy. This is her story of finding that for herself, and then spreading it to an entire world.

    One day he was a doctor treating the dying, and the next he was a patient struggling to live. And just like that, the future he and his wife had imagined evaporated. When Breath Becomes Air chronicles Kalanithi's transformation from a naïve medical student "possessed," as he wrote, "by the question of what, given that all organisms die, makes a virtuous and meaningful life" into a neurosurgeon at Stanford working in the brain, the most critical place for human identity, and finally into a patient and new father confronting his own mortality. What makes life worth living in the face of death? What do you do when the future, no longer a ladder toward your goals in life, flattens out into a perpetual present? What does it mean to have a child, to nurture a new life as another fades away? These are some of the questions Kalanithi wrestles with in this profoundly moving, exquisitely observed memoir. Paul Kalanithi died in March 2015, while working on this book, yet his words live on as a guide and a gift to us all. "I began to realize that coming face to face with my own mortality, in a sense, had changed nothing and everything," he wrote. "Seven words from Samuel Beckett began to repeat in my head: 'I can't go on. I'll go on.'" When Breath Becomes Air is an unforgettable, life-affirming reflection on the challenge of facing death and on the relationship between doctor and patient, from a brilliant writer who became both.

    Eilene Zimmerman noticed that her ex-husband looked thin, seemed distracted, and was frequently absent from activities with their children. She thought he looked sick and needed to see a doctor, and indeed, he told her he had been diagnosed with an autoimmune disorder. Yet in many ways, Peter also seemed to have it all: a beautiful house by the beach purchased after their divorce, expensive cars, and other luxuries that came with an affluent life. Eilene assumed his odd behavior was due to stress and overwork--he was a senior partner at a prominent law firm and had been working more than 60 hours a week for the last 20 years.Although they were divorced, Eilene and Peter had been partners and friends for decades, so, when her calls to Peter were not returned for several days, Eilene went to his house to see if he was OK.So begins Smacked, a brilliant, moving memoir of Eilene's shocking discovery, one that sets her on a journey to find out how a man she knew for nearly 30 years became a drug addict, and hid it so well that neither she nor anyone else in his life suspected what was happening. Eilene discovers that Peter led a secret life, one that started with pills and ended with opioids, cocaine and methamphetamine. Peter was also addicted to work; the last call he ever made was to dial into a conference call.Eilene is determined to learn all she can about Peter's hidden life, and also about drug addiction among ambitious and high achieving professionals like him. Through extensive research and interviews, she presents a picture of drug dependence today in that moneyed, upwardly mobile world. She also embarks on a journey to recreate her life in the wake of loss, both of the person--and the relationship--that profoundly defined the woman she had become.Smacked takes readers on an intimate journey into a little-known part of the drug epidemic, through the story of one man, one woman and one family.

    In 2018, he was the owner and chef of his own restaurant empire, with 15 locations from New York to Australia, the star of his own hit Netflix show and podcast, was named one of the most influential people of the 21st century and had a following of over 1.2 million. In this inspiring, honest and heartfelt memoir, Chang shares the extraordinary story of his culinary coming-of-age.Growing up in Virginia, the son of Korean immigrant parents, Chang struggled with feelings of abandonment, isolation and loneliness throughout his childhood. After failing to find a job after graduating, he convinced his father to loan him money to open a restaurant. Momofuku's unpretentious air and great-tasting simple staples - ramen bowls and pork buns - earned it rave reviews, culinary awards and before long, Chang had a cult following.Momofuku's popularity continued to grow with Chang opening new locations across the U.S. and beyond. In 2009, his Ko restaurant received two Michelin stars and Chang went on to open Milk Bar, Momofuku's bakery. By 2012, he had become a restaurant mogul with the opening of the Momofuku building in Toronto, encompassing three restaurants and a bar.Chang's love of food and cooking remained a constant in his life, despite the adversities he had to overcome. Over the course of his career, the chef struggled with suicidal thoughts, depression and anxiety. He shied away from praise and begged not to be given awards. In Eat a Peach, Chang opens up about his feelings of paranoia, self-confidence and pulls back the curtain on his struggles, failures and learned lessons. Deeply personal, honest and humble, Chang's story is one of passion and tenacity, against the odds.

    He’s an established legend, having starred in Mary Poppins, Chitty Chitty Bang Bang, and The Dick Van Dyke Show. And yet he’s still keeping himself busy, entertaining America on television, movies, the stage, and social media. Everyone wonders, “How does he do it?” For the first time, Van Dyke shares his secrets and tips on old age: Just keep moving. In a fun and folksy way of addressing readers, Keep Moving serves as an instruction book on how to embrace old age with a positive attitude. The chapters are filled with exclusive personal anecdotes that explore various themes on aging: how to adapt to the physical and social changes, deal with loss of friends and loved ones, stay current, fall in love again, and “keep moving” every day like there’s no tomorrow.

    It is a poignant observation about the relationship between Mira, her sister, and their mentally ill mother. Before she was struck with schizophrenia at the age of nineteen, beautiful piano protégé Norma Herr had been the most vibrant personality in the room. She loved her daughters and did her best to raise them well, but as her mental state deteriorated, Norma spoke less about Chopin and more about Nazis and her fear that her daughters would be kidnapped, murdered, or raped. When the girls left for college, the harassment escalated--Norma called them obsessively, appeared at their apartments or jobs, threatened to kill herself if they did not return home. After a traumatic encounter, Mira and her sister were left with no choice but to change their names and sever all contact with Norma in order to stay safe. But while Mira pursued her career as an artist--exploring the ancient romance of Florence, the eerie mysticism of northern Norway, and the raw desert of Israel--the haunting memories of her mother were never far away. Then one day, Mira’s life changed forever after a debilitating car accident. As she struggled to recover from a traumatic brain injury, she was confronted with a need to recontextualize her life--she had to relearn how to paint, read, and interact with the outside world. In her search for a way back to her lost self, Mira reached out to the homeless shelter where she believed her mother was living and discovered that Norma was dying. Mira and her sister traveled to Cleveland, where they shared an extraordinary reconciliation with their mother that none of them had thought possible. At the hospital, Mira discovered a set of keys that opened a storage unit Norma had been keeping for seventeen years. Filled with family photos, childhood toys, and ephemera from Norma’s life, the storage unit brought back a flood of previous memories that Mira had thought were lost to her forever. The Memory Palace is a breathtaking literary memoir about the complex meaning of love, truth, and the capacity for forgiveness among family. Through stunning prose and original art created by the author in tandem with the text, The Memory Palace explores the connections between mother and daughter that cannot be broken no matter how much exists--or is lost--between them.

    But her story has had its obstacles, including being her own parent, living in her car as a teenager, and moving to New York City to pursue her dreams. Through it all, she looked to movies, TV, and music as the family and support systems she never had.From spending the holidays alone to having better “stranger luck” than with those closest to her to feeling like the last hopeless romantic on earth, Lane reveals her powerful and entertaining journey in all its candor, anxiety, and ultimate acceptance—with humor always her bolstering force and greatest gift.How to Be Alone is a must-read for anyone whose childhood still feels unresolved, who spends more time pretending to have friends online than feeling close to anyone in real life, who tries to have genuine, deep conversations in a roomful of people who would rather you not. Above all, it’s a book for anyone who desperately wants to feel less alone and a little more connected through reading her words.

    And that's what Furiously Happy is all about."Jenny’s readings are standing room only, with fans lining up to have Jenny sign their bottles of Xanax or Prozac as often as they are to have her sign their books. Furiously Happy appeals to Jenny's core fan base but also transcends it. There are so many people out there struggling with depression and mental illness, either themselves or someone in their family—and in Furiously Happy they will find a member of their tribe offering up an uplifting message (via a taxidermied roadkill raccoon). Let's Pretend This Never Happened ostensibly was about embracing your own weirdness, but deep down it was about family. Furiously Happy is about depression and mental illness, but deep down it's about joy—and who doesn't want a bit more of that?