From dramatic, high-risk spacewalks to author Scott Parazynski’s death-defying quest to summit Mount Everest—his body ravaged by a career in space—readers will experience the life of an elite athlete, physician, and explorer.This intimate, compelling account offers a rare portrait of space exploration from the inside. A global nomad raised in the shadow of NASA’s Apollo missions, Parazynski never lost sight of his childhood dream to one day don a spacesuit and float outside the airlock. With deep passion, unbridled creativity, resilience, humility, and self-deprecation, Parazynski chases his dream of the ultimate adventure experience, again and again and again. In an era that transitioned from moon shots to the Space Shuttle, space station, and Mars research, Parazynski flies with John Glenn, tests jet packs, trains in Russia to become a cosmonaut, and flies five missions to outer space (including seven spacewalks) in his seventeen-year NASA career.An unparalleled, visceral opportunity to understand what it’s like to train for—and deploy to—a home in zero gravity, The Sky Below also portrays an astronaut’s engagement with the challenges of his life on Earth, including raising a beautiful autistic daughter and finding true love.

    Tell Me Where It Hurts: A Day of Humor, Healing, and Hope in My Life as an Animal Surgeon

    But sometimes, when obsession gets the better of scientists, they twist a noble pursuit into something sinister. Under this spell, knowledge isn’t everything, it’s the only thing—no matter the cost. Bestselling author Sam Kean tells the true story of what happens when unfettered ambition pushes otherwise rational men and women to cross the line in the name of science, trampling ethical boundaries and often committing crimes in the process.The Icepick Surgeon masterfully guides the reader across two thousand years of history, beginning with Cleopatra’s dark deeds in ancient Egypt. The book reveals the origins of much of modern science in the transatlantic slave trade of the 1700s, as well as Thomas Edison’s mercenary support of the electric chair and the warped logic of the spies who infiltrated the Manhattan Project. But the sins of science aren’t all safely buried in the past. Many of them, Kean reminds us, still affect us today. We can draw direct lines from the medical abuses of Tuskegee and Nazi Germany to current vaccine hesitancy, and connect icepick lobotomies from the 1950s to the contemporary failings of mental-health care. Kean even takes us into the future, when advanced computers and genetic engineering could unleash whole new ways to do one another wrong.Unflinching, and exhilarating to the last page, The Icepick Surgeon fuses the drama of scientific discovery with the illicit thrill of a true-crime tale. With his trademark wit and precision, Kean shows that, while science has done more good than harm in the world, rogue scientists do exist, and when we sacrifice morals for progress, we often end up with neither.

    His contribution to our understanding not only of mental illness but also of the human condition is truly stunning.The Noonday Demon examines depression in personal, cultural, and scientific terms. Drawing on his own struggles with the illness and interviews with fellow sufferers, doctors and scientists, policymakers and politicians, drug designers and philosophers, Solomon reveals the subtle complexities and sheer agony of the disease. He confronts the challenge of defining the illness and describes the vast range of available medications, the efficacy of alternative treatments, and the impact the malady has had on various demographic populations around the world and throughout history. He also explores the thorny patch of moral and ethical questions posed by emerging biological explanations for mental illness.The depth of human experience Solomon chronicles, the range of his intelligence, and his boundless curiosity and compassion will change the reader's view of the world.

    Robert D. Lesslie, it's a foundation for inspiring stories of everyday "angels"—friends, nurses, doctors, patients, and even strangers who offer love, help, and support in the midst of trouble."The ER is a difficult and challenging place to be. Yet the same pressures and stresses that make this place so challenging also provide an opportunity to experience some of life's greatest wonders and mysteries." Dr. Lesslie illuminates messages of hope while sharing fast-paced, captivating stories aboutdiscovering lessons from the ER frontlinewatching everyday miracles unfoldholding on to faith during tragedy and triumphembracing the healing balm of hopeFor anyone who enjoys true stories of the wonders of the human spirit, this immensely popular book is a reminder that hope can turn emergencies into opportunities and trials into demonstrations of God's grace.

    Leslie Jamison deftly excavates the stories we tell about addiction--both her own and others'--and examines what we want these stories to do, and what happens when they fail us.All the while, she offers a fascinating look at the larger history of the recovery movement, and at the literary and artistic geniuses whose lives and works were shaped by alcoholism and substance dependence, including John Berryman, Jean Rhys, Raymond Carver, Billie Holiday, David Foster Wallace, and Denis Johnson, as well as brilliant figures lost to obscurity but newly illuminated here.For the power of her striking language and the sharpness of her piercing observations, Jamison has been compared to such iconic writers as Joan Didion and Susan Sontag. Yet her utterly singular voice also offers something new. With enormous empathy and wisdom, Jamison has given us nothing less than the story of addiction and recovery in America writ large, a definitive and revelatory account that will resonate for years to come.

    In the span of twelve hours, lives can be lost, life-altering medical treatment decisions made, and dreams fulfilled or irrevocably stolen. In Brown’s skilled hands--as both a dedicated nurse and an insightful chronicler of events--we are given an unprecedented view into the individual struggles as well as the larger truths about medicine in this country, and by shift’s end, we have witnessed something profound about hope and healing and humanity. Every day, Theresa Brown holds patients' lives in her hands. On this day there are four. There is Mr. Hampton, a patient with lymphoma to whom Brown is charged with administering a powerful drug that could cure him--or kill him; Sheila, who may have been dangerously misdiagnosed; Candace, a returning patient who arrives (perhaps advisedly) with her own disinfectant wipes, cleansing rituals, and demands; and Dorothy, who after six weeks in the hospital may finally go home. Prioritizing and ministering to their needs takes the kind of skill, sensitivity, and, yes, humor that enable a nurse to be a patient’s most ardent advocate in a medical system marked by heartbreaking dysfunction as well as miraculous success.

    Obsessive and inspired efforts by scientists to solve mysteries and save lives. From The Hot Zone to The Demon in the Freezer and beyond, Richard Preston’s bestselling works have mesmerized readers everywhere by showing them strange worlds of nature they never dreamed of.Panic in Level 4 is a grand tour through the eerie and unforgettable universe of Richard Preston, filled with incredible characters and mysteries that refuse to leave one’s mind. Here are dramatic true stories from this acclaimed and award-winning author, including:• The phenomenon of “self-cannibals,” who suffer from a rare genetic condition caused by one wrong letter in their DNA that forces them to compulsively chew their own flesh–and why everyone may have a touch of this disease.• The search for the unknown host of Ebola virus, an organism hidden somewhere in African rain forests, where the disease finds its way into the human species, causing outbreaks of unparalleled horror.• The brilliant Russian brothers–“one mathematician divided between two bodies”–who built a supercomputer in their apartment from mail-order parts in an attempt to find hidden order in the number pi (π).In fascinating, intimate, and exhilarating detail, Richard Preston portrays the frightening forces and constructive discoveries that are currently roiling and reordering our world, once again proving himself a master of the nonfiction narrative and, as noted in The Washington Post, “a science writer with an uncommon gift for turning complex biology into riveting page-turners.”From the Hardcover edition.

    The childhood illness that left her bedridden for a year, which she was not expected to survive. A teenage yearning to escape that nearly ended in disaster. An encounter with a disturbed man on a remote path. And, most terrifying of all, an ongoing, daily struggle to protect her daughter--for whom this book was written--from a condition that leaves her unimaginably vulnerable to life's myriad dangers.Seventeen discrete encounters with Maggie at different ages, in different locations, reveal a whole life in a series of tense, visceral snapshots. In taut prose that vibrates with electricity and restrained emotion, O'Farrell captures the perils running just beneath the surface, and illuminates the preciousness, beauty, and mysteries of life itself.

    The Psychopath Test is a fascinating journey through the minds of madness. Jon Ronson's exploration of a potential hoax being played on the world's top neurologists takes him, unexpectedly, into the heart of the madness industry. An influential psychologist who is convinced that many important CEOs and politicians are, in fact, psychopaths teaches Ronson how to spot these high-flying individuals by looking out for little telltale verbal and nonverbal clues. And so Ronson, armed with his new psychopath-spotting abilities, enters the corridors of power. He spends time with a death-squad leader institutionalized for mortgage fraud in Coxsackie, New York; a legendary CEO whose psychopathy has been speculated about in the press; and a patient in an asylum for the criminally insane who insists he's sane and certainly not a psychopath. Ronson not only solves the mystery of the hoax but also discovers, disturbingly, that sometimes the personalities at the helm of the madness industry are, with their drives and obsessions, as mad in their own way as those they study. And that relatively ordinary people are, more and more, defined by their maddest edges.

    Months later, several health professionals faced criminal allegations that they deliberately injected numerous patients with drugs to hasten their deaths. Five Days at Memorial, the culmination of six years of reporting, unspools the mystery of what happened in those days, bringing the reader into a hospital fighting for its life and into a conversation about the most terrifying form of health care rationing.In a voice at once involving and fair, masterful and intimate, Fink exposes the hidden dilemmas of end-of-life care and reveals just how ill-prepared we are in America for the impact of large-scale disasters—and how we can do better. A remarkable book, engrossing from start to finish, Five Days at Memorial radically transforms your understanding of human nature in crisis.

    Brought up in Washington, DC, in an abusive family, she went to Harvard, where she met her husband. They stayed together through medical school until two months before she was scheduled to join the staff of a hospital in central Philadelphia, when he told her he couldn't move with her. Her marriage at an end, Harper began her new life in a new city, in a new job, as a newly single woman.In the ensuing years, as Harper learned to become an effective ER physician, bringing insight and empathy to every patient encounter, she came to understand that each of us is broken—physically, emotionally, psychically. How we recognize those breaks, how we try to mend them, and where we go from there are all crucial parts of the healing process.The Beauty in Breaking is the poignant true story of Harper's journey toward self-healing. Each of the patients Harper writes about taught her something important about recuperation and recovery. How to let go of fear even when the future is murky. How to tell the truth when it's simpler to overlook it. How to understand that compassion isn't the same as justice. As she shines a light on the systemic disenfranchisement of the patients she treats as they struggle to maintain their health and dignity, Harper comes to understand the importance of allowing ourselves to make peace with the past as we draw support from the present. In this hopeful, moving, and beautiful book, she passes along the precious, necessary lessons that she has learned as a daughter, a woman, and a physician.

    Readers of "The New Yorker" may be familiar with the author's suspenseful tales of strange illnesses, rare diseases, poisons and parasites.

    At the end of the nineteenth century, serial murderer Joseph Vacher, known and feared as "The Killer of Little Shepherds," terrorized the French countryside. He eluded authorities for years--until he ran up against prosecutor Emile Fourquet and Dr. Alexandre Lacassagne, the era's most renowned criminologist. The two men--intelligent and bold--typified the Belle Epoque, a period of immense scientific achievement and fascination with science's promise to reveal the secrets of the human condition. With high drama and stunning detail, Douglas Starr revisits Vacher's infamous crime wave, interweaving the story of how Lacassagne and his colleagues were developing forensic science as we know it. We see one of the earliest uses of criminal profiling, as Fourquet painstakingly collects eyewitness accounts and constructs a map of Vacher's crimes. We follow the tense and exciting events leading to the murderer's arrest. And we witness the twists and turns of the trial, celebrated in its day. In an attempt to disprove Vacher's defense by reason of insanity, Fourquet recruits Lacassagne, who in the previous decades had revolutionized criminal science by refining the use of blood-spatter evidence, systematizing the autopsy, and doing groundbreaking research in psychology. Lacassagne's efforts lead to a gripping courtroom denouement. "The Killer of Little Shepherds" is an important contribution to the history of criminal justice, impressively researched and thrillingly told.

    Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings? A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.