Two scientists explore the potential of a revolutionary genetics technology capable of easily and affordably manipulating DNA in human embryos to prevent specific diseases, addressing key concerns about related ethical and societal repercussions.

    Hallucinating that she looked like Shrek was terrifying, but it led to her first diagnosis and the start of a journey towards self-awareness, acceptance, success, and ultimately, joy. With humor and candor, Gotch shares the empowering story of her unlikely path to becoming the creator and CCO of a multimillion-dollar brand. From her childhood in Florida where her early struggles with bipolar disorder, generalized anxiety, and ADD were misdiagnosed, to her winding career path as a waitress, photographer, food stylist, and finally, accidental entrepreneur, she illuminates how embracing her flaws and understanding the influence of mental illness on her creativity actually led to her greatest successes in business and life. Hilarious, hyper-relatable, and filled with fascinating insights and hard-won wisdom on everything from why it’s okay to cry at work to the myth of busyness and perfection to the emotional rating system she uses every day, Gotch’s inspirational memoir dares readers to live each day with hope, optimism, kindness, and humor.

    His passion for and genuine curiosity about the people and cultures he visited made the world feel smaller and more connected. Despite his affable, confident, and trademark snarky TV persona, the real Tony was intensely private, deeply conflicted about his fame, and an enigma even to those close to him. Tony’s devoted crew knew him best, and no one else had a front-row seat for as long as his director and producer, Tom Vitale.Over the course of more than a decade traveling together, Tony became a boss, a friend, a hero and, sometimes, a tormentor.In the Weeds takes readers behind the scenes to reveal not just the insanity that went into filming in some of the most far-flung and volatile parts of the world, but what Tony was like unedited and off-camera. From the outside, the job looked like an all-expenses-paid adventure to places like Borneo, Vietnam, Iran, the Democratic Republic of Congo, and Libya. What happened off-camera was far more interesting than what made it to air. The more things went wrong, the better it was for the show. Fortunately, everything fell apart constantly.

    She writes songs about her anatomy, talks trash about her one-eyed rescue pug, and sexually harasses her husband, Stephen. And it pays the bills! Now, in her first-ever book, Laura recounts how she went from being a dangerously impulsive, broke, unemployable, suicidal, cocaine-addicted narcissist, crippled by fear and hopping from one toxic romance to the next…to a more-happy-than-not, somewhat rational, meditating, vegan yogi with good credit, a great marriage, a fantastic career, and four unfortunate-looking rescue animals. Still, above all, Laura remains an amazingly talented, adorable, and vulnerable, self-described…Idiot. With her signature brand of offbeat, no-holds-barred humor, Idiot introduces you to a wildly original—and undeniably relatable—new voice.Oh, the places I've peed --High school Hammer time --My summer of (possibly too much) freedom --How to ignore a hundred red flags --The Damon inside --A spoonful of sugar --Look, Mom! I'm on TV! --New beginnings (but, like, for real) --Two apartments and a home --Maggie: cat --Walking through fear

    From training to launch, from his historic spacewalk to re-entry, he reveals for readers of all ages the cutting-edge science behind his ground-breaking experiments, and the wonders of day-to-day life on board the International Space Station.The public were invited to submit questions using the hashtag #askanastronaut, and a selection are answered by Tim in the book, which will be accompanied with illustrations, diagrams and never-before-seen photos.Tim is pleased to announce that, as with his previous book, royalties received from the book will be donated to The Prince’s Trust.

    The child of two lawyers, they are staunchly anti-death penalty. But the moment convicted murderer Ricky Langley’s face flashes on the screen as they review old tapes—the moment they hear him speak of his crimes -- they are overcome with the feeling of wanting him to die. Shocked by their reaction, they dig deeper and deeper into the case. Despite their vastly different circumstances, something in his story is unsettlingly, uncannily familiar.Crime, even the darkest and most unsayable acts, can happen to any one of us. As Alex pores over the facts of the murder, they find themself thrust into the complicated narrative of Ricky’s childhood. And by examining the details of Ricky’s case, they are forced to face their own story, to unearth long-buried family secrets, and reckon with a past that colors their view of Ricky's crime.But another surprise awaits: They weren’t the only one who saw their life in Ricky’s.An intellectual and emotional thriller that is also a different kind of murder mystery, THE FACT OF A BODY is a book not only about how the story of one crime was constructed -- but about how we grapple with our own personal histories. Along the way it tackles questions about the nature of forgiveness, and if a single narrative can ever really contain something as definitive as the truth. This groundbreaking, heart-stopping work, ten years in the making, shows how the law is more personal than we would like to believe -- and the truth more complicated, and powerful, than we could ever imagine.

    The answers are best found not in jurisprudence but in science: the curious science of human-wildlife conflict, a discipline at the crossroads of human behavior and wildlife biology.Roach tags along with animal-attack forensics investigators, human-elephant conflict specialists, bear managers, and "danger tree" faller blasters. Intrepid as ever, she travels from leopard-terrorized hamlets in the Indian Himalaya to St. Peter’s Square in the early hours before the pope arrives for Easter Mass, when vandal gulls swoop in to destroy the elaborate floral display. She taste-tests rat bait, learns how to install a vulture effigy, and gets mugged by a macaque.Combining little-known forensic science and conservation genetics with a motley cast of laser scarecrows, langur impersonators, and trespassing squirrels, Roach reveals as much about humanity as about nature’s lawbreakers. When it comes to "problem" wildlife, she finds, humans are more often the problem—and the solution. Fascinating, witty, and humane, Fuzz offers hope for compassionate coexistence in our ever-expanding human habitat.

    She was a poor Southern tobacco farmer who worked the same land as her enslaved ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine. The first “immortal” human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. If you could pile all HeLa cells ever grown onto a scale, they’d weigh more than 50 million metric tons—as much as a hundred Empire State Buildings. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions.Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave.Now Rebecca Skloot takes us on an extraordinary journey, from the “colored” ward of Johns Hopkins Hospital in the 1950s to stark white laboratories with freezers full of HeLa cells; from Henrietta’s small, dying hometown of Clover, Virginia — a land of wooden quarters for enslaved people, faith healings, and voodoo — to East Baltimore today, where her children and grandchildren live and struggle with the legacy of her cells.Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family — past and present — is inextricably connected to the history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of.Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah, who was devastated to learn about her mother’s cells. She was consumed with questions: Had scientists cloned her mother? Did it hurt her when researchers infected her cells with viruses and shot them into space? What happened to her sister, Elsie, who died in a mental institution at the age of fifteen? And if her mother was so important to medicine, why couldn’t her children afford health insurance?Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.

    By that afternoon, she saw the world—quite literally—upside down. By New Year’s Day, she was unable to form a coherent sentence. And after hours in the ER, days in the hospital, and multiple questions and tests, her doctors informed her that she had had a stroke. For months afterward, Lee outsourced her memories to a journal, taking diligent notes to compensate for the thoughts she could no longer hold on to. It is from these notes that she has constructed this frank and compelling memoir.In a precise and captivating narrative, Lee navigates fearlessly between chronologies, weaving her childhood humiliations and joys together with the story of the early days of her marriage; and then later, in painstaking, painful, and unflinching detail, the account of her stroke and every upset—temporary or permanent—that it caused. Lee illuminates the connection between memory and identity in an honest, meditative, and truly funny manner, utterly devoid of self-pity. And as she recovers, she begins to realize that this unexpected and devastating event has provided a catalyst for coming to terms with her true self—and, in a way, has allowed her to become the person she’s always wanted to be.

    Julia Cooke’s intimate storytelling weaves together the real-life stories of a memorable cast of characters, from Lynne Totten, a science major who decided life in a lab was not for her, to Hazel Bowie, one of the relatively few black stewardesses of the era, as they embraced the liberation of their new jet-set life. Cooke brings to life the story of Pan Am stewardesses’ role in the Vietnam War, as the airline added runs from Saigon to Hong Kong for planeloads of weary young soldiers straight from the battlefields, who were off for five days of R&R, and then flown back to war. Finally, with Operation Babylift—the dramatic evacuation of 2,000 children during the fall of Saigon—the book’s special cast of stewardesses unites to play an extraordinary role on the world stage.

    After World War II, Don's work with the Air Force brought them to Colorado, where their twelve children perfectly spanned the baby boom: the oldest born in 1945, the youngest in 1965. In those years, there was an established script for a family like the Galvins—aspiration, hard work, upward mobility, domestic harmony—and they worked hard to play their parts. But behind the scenes was a different story: psychological breakdown, sudden shocking violence, hidden abuse. By the mid-1970s, six of the ten Galvin boys, one after another, were diagnosed as schizophrenic. How could all this happen to one family?What took place inside the house on Hidden Valley Road was so extraordinary that the Galvins became one of the first families to be studied by the National Institute of Mental Health. Their story offers a shadow history of the science of schizophrenia, from the era of institutionalization, lobotomy, and the schizophrenogenic mother to the search for genetic markers for the disease, always amid profound disagreements about the nature of the illness itself. And unbeknownst to the Galvins, samples of their DNA informed decades of genetic research that continues today, offering paths to treatment, prediction, and even eradication of the disease for future generations.With clarity and compassion, bestselling and award-winning author Robert Kolker uncovers one family's unforgettable legacy of suffering, love, and hope.

    Thanks to the introduction of free-roaming cattle, ponies, pigs and deer – proxies of the large animals that once roamed Britain – the 3,500 acre project has seen extraordinary increases in wildlife numbers and diversity in little over a decade.Once-common species, including turtle doves, nightingales, peregrine falcons, lesser spotted woodpeckers and purple emperor butterflies, are now breeding at Knepp, and populations of other species are rocketing. The Burrells’ degraded agricultural land has become a functioning ecosystem again, heaving with life – all by itself.This recovery has taken place against a backdrop of catastrophic loss elsewhere. According to the 2016 ‘State of Nature’ report, the UK is ranked 29th in the world for biodiversity loss: 56% of species in the UK are in decline and 15% are threatened with extinction. We are living in a desert, compared with our gloriously wild past.In Wilding, Isabella Tree tells the story of the ‘Knepp experiment’ and what it reveals of the ways in which we might regain that wilder, richer country. It shows how rewilding works across Europe; that it has multiple benefits for the land; that it can generate economic activity and employment; how it can benefit both nature and us – and that all of this can happen astonishingly quickly. Part gripping memoir, part fascinating account of the ecology of our countryside, Wilding is, above all, an inspiring story of hope.

    "Go ahead, ask your question," her father urged, nudging her forward. She smiled shyly and said, "You're my hero. Who's yours?" Many people - especially girls - have asked us that same question over the years. It's one of our favourite topics.HILLARY: Growing up, I knew hardly any women who worked outside the home. So I looked to my mother, my teachers, and the pages of Life magazine for inspiration. After learning that Amelia Earhart kept a scrapbook with newspaper articles about successful women in male-dominated jobs, I started a scrapbook of my own. Long after I stopped clipping articles, I continued to seek out stories of women who seemed to be redefining what was possible.CHELSEA: This book is the continuation of a conversation the two of us have been having since I was little. For me, too, my mom was a hero; so were my grandmothers. My early teachers were also women. But I grew up in a world very different from theirs. My pediatrician was a woman, and so was the first mayor of Little Rock who I remember from my childhood. Most of my close friends' moms worked outside the home as nurses, doctors, teachers, professors, and in business. And women were going into space and breaking records here on Earth.Ensuring the rights and opportunities of women and girls remains a big piece of the unfinished business of the twenty-first century. While there's a lot of work to do, we know that throughout history and around the globe women have overcome the toughest resistance imaginable to win victories that have made progress possible for all of us. That is the achievement of each of the women in this book.So how did they do it? The answers are as unique as the women themselves. Civil rights activist Dorothy Height, LGBTQ trailblazer Edie Windsor, and swimmer Diana Nyad kept pushing forward, no matter what. Writers like Rachel Carson and Chimamanda Ngozi Adichie named something no one had dared talk about before. Historian Mary Beard used wit to open doors that were once closed, and Wangari Maathai, who sparked a movement to plant trees, understood the power of role modeling. Harriet Tubman and Malala Yousafzai looked fear in the face and persevered. Nearly every single one of these women was fiercely optimistic - they had faith that their actions could make a difference. And they were right.To us, they are all gutsy women - leaders with the courage to stand up to the status quo, ask hard questions, and get the job done. So in the moments when the long haul seems awfully long, we hope you will draw strength from these stories. We do. Because if history shows one thing, it's that the world needs gutsy women.

    Mikel Jollett was born into one of the country’s most infamous cults, and subjected to a childhood filled with poverty, addiction, and emotional abuse. Yet, ultimately, his is a story of fierce love and family loyalty told in a raw, poetic voice that signals the emergence of a uniquely gifted writer.We were never young. We were just too afraid of ourselves. No one told us who we were or what we were or where all our parents went. They would arrive like ghosts, visiting us for a morning, an afternoon. They would sit with us or walk around the grounds, to laugh or cry or toss us in the air while we screamed. Then they’d disappear again, for weeks, for months, for years, leaving us alone with our memories and dreams, our questions and confusion. …So begins Hollywood Park, Mikel Jollett’s remarkable memoir. His story opens in an experimental commune in California, which later morphed into the Church of Synanon, one of the country’s most infamous and dangerous cults. Per the leader’s mandate, all children, including Jollett and his older brother, were separated from their parents when they were six months old, and handed over to the cult’s “School.” After spending years in what was essentially an orphanage, Mikel escaped the cult one morning with his mother and older brother. But in many ways, life outside Synanon was even harder and more erratic.In his raw, poetic and powerful voice, Jollett portrays a childhood filled with abject poverty, trauma, emotional abuse, delinquency and the lure of drugs and alcohol. Raised by a clinically depressed mother, tormented by his angry older brother, subjected to the unpredictability of troubled step-fathers and longing for contact with his father, a former heroin addict and ex-con, Jollett slowly, often painfully, builds a life that leads him to Stanford University and, eventually, to finding his voice as a writer and musician.Hollywood Park is told at first through the limited perspective of a child, and then broadens as Jollett begins to understand the world around him. Although Mikel Jollett’s story is filled with heartbreak, it is ultimately an unforgettable portrayal of love at its fiercest and most loyal.

    In her brutally honest, hilarious, heartbreaking memoir, she reveals what was going on behind the scenes of her sometimes tumultuous personal and professional life - a story she’s never shared, until now. Of the medium she loves, the one that made her a household name, she says, “Television can put you in a box; the flat-screen can flatten. On TV, you are larger than life but smaller, too. It is not the whole story, and it is not the whole me. This book is.”Beginning in early childhood, Couric was inspired by her journalist father to pursue the career he loved but couldn’t afford to stay in. Balancing her vivacious, outgoing personality with her desire to be taken seriously, she overcame every obstacle in her way: insecurity, an eating disorder, being typecast, sexism . . . challenges, and how she dealt with them, setting the tone for the rest of her career. Couric talks candidly about adjusting to sudden fame after her astonishing rise to co-anchor of the TODAY show, and guides us through the most momentous events and news stories of the era, to which she had a front-row seat:  Rodney King, Anita Hill, Columbine, the death of Princess Diana, 9/11, the Iraq War . . . In every instance, she relentlessly pursued the facts, ruffling more than a few feathers along the way.  She also recalls in vivid and sometimes lurid detail the intense pressure on female anchors to snag the latest “get”—often sensational tabloid stories like Jon Benet Ramsey, Tonya Harding, and OJ Simpson.Couric’s position as one of the leading lights of her profession was  shadowed by the shock and trauma of losing her husband to stage 4 colon cancer when he was just 42, leaving her a widow and single mom to two daughters, 6 and 2. The death of her sister Emily, just three years later, brought yet more trauma—and an unwavering commitment to cancer awareness and research, one of her proudest accomplishments. Couric is unsparing in the details of her historic move to the anchor chair at the CBS Evening News—a world rife with sexism and misogyny.  Her “welcome” was even more hostile at 60 Minutes, an unrepentant boys club that engaged in outright hazing of even the most established women.  In the wake of the MeToo movement, Couric shares her clear-eyed reckoning with gender inequality and predatory behavior in the workplace, and downfall of Matt Lauer—a colleague she had trusted and respected for more than a decade.Couric also talks about the challenge of finding love again, with all the hilarity, false-starts, and drama that search entailed, before finding her midlife Mr. Right.  Something she has never discussed publicly—why her second marriage almost didn’t happen. If you thought you knew Katie Couric, think again. Going There is the fast-paced, emotional, riveting story of a thoroughly modern woman, whose journey took her from humble origins to superstardom. In these pages, you will find a friend, a confidante, a role model, a survivor whose lessons about life will enrich your own.