Intuitive Biostatistics covers all the topics typically found in an introductory statistics text, but with the emphasis on confidence intervals rather than P values, making it easier for students to understand both. Additionally, it introduces a broad range of topics left out of most other introductory texts but used frequently in biomedical publications, including survival curves. multiple comparisons, sensitivity and specificity of lab tests, Bayesian thinking, lod scores, and logistic, proportional hazards and nonlinear regression. By emphasizing interpretation rather than calculation, this text provides a clear and virtually painless introduction to statistical principles for those students who will need to use statistics constantly in their work. In addition, its practical approach enables readers to understand the statistical results published in biological and medical journals.

    At the dawn of the Industrial Revolution in eighteenth-century England, standards of measurement were established, giving way to the development of machine tools—machines that make machines. Eventually, the application of precision tools and methods resulted in the creation and mass production of items from guns and glass to mirrors, lenses, and cameras—and eventually gave way to further breakthroughs, including gene splicing, microchips, and the Hadron Collider.Simon Winchester takes us back to origins of the Industrial Age, to England where he introduces the scientific minds that helped usher in modern production: John Wilkinson, Henry Maudslay, Joseph Bramah, Jesse Ramsden, and Joseph Whitworth. It was Thomas Jefferson who later exported their discoveries to the fledgling United States, setting the nation on its course to become a manufacturing titan. Winchester moves forward through time, to today’s cutting-edge developments occurring around the world, from America to Western Europe to Asia.As he introduces the minds and methods that have changed the modern world, Winchester explores fundamental questions. Why is precision important? What are the different tools we use to measure it? Who has invented and perfected it? Has the pursuit of the ultra-precise in so many facets of human life blinded us to other things of equal value, such as an appreciation for the age-old traditions of craftsmanship, art, and high culture? Are we missing something that reflects the world as it is, rather than the world as we think we would wish it to be? And can the precise and the natural co-exist in society?

    Being Mortal by Atul Gawande - A 20-minute Summary Inside this Instaread Summary: • Overview of the entire book• Introduction to the important people in the book• Summary and analysis of all the chapters in the book• Key Takeaways of the book• A Reader's Perspective Preview of this summary: Chapter 1 Gawande grew up in Ohio. His parents were immigrants from India and both were doctors. His grandparents stayed in India, and there were few older people in his neighborhood, so he had little experience with aging or death until he met his wife’s grandmother, Alice Hobson. Hobson was seventy-seven and living on her own in Virginia. She was a spirited widow who fixed her own plumbing and volunteered with Meals On Wheels. However, Hobson was losing strength and height steadily each year as her arthritis worsened.Gawande’s father enthusiastically adopted the customs of his new country, but he could not understand the way in which seniors were treated in the US. In India, the elderly were treated with great respect and lived out their lives with family.In the United States, Sitaram Gawande, Gawande’s grandfather, likely would have been sent to a nursing home like most of the elderly who cannot handle the basics of daily living by themselves. However, in India, Sitaram Gawande was able to live in his own home and manage his own affairs, with family constantly around him. He died at the age of one hundred and ten when he fell off a bus during a business trip.Until recently, most elderly people stayed with their families. Even as the nuclear family unit became predominant, replacing the multi-generational family unit, people cared for their elderly relatives. Families were large and one child, usually a daughter, would not marry in order to take care of the parents.This has changed in much of the world, where elderly people end up struggling to live alone, like Hobson, rather than living with dignity amid family, like Sitaram Gawande.One cause of this change can be found in the nature of knowledge. When few people lived to be very old, elders were honored. Their store of knowledge was greatly useful. People often portrayed themselves as older to command respect. Modern society’s emphasis on youth is a complete reversal of this attitude. Technological advances are perceived as the territory of the young, and everyone wants to be younger. High-tech job opportunities are all over the world, and young people do not hesitate to leave their parents behind to pursue them.In developed countries, parents embrace the concept of a retirement filled with leisure activities. Parents are happy to begin living for themselves once children are grown. However, this system only works for young, healthy retirees, but not for those who cannot continue to be independent. Hobson, for example, was falling frequently and suffering memory lapses. Her doctor did tests and wrote prescriptions, but did not know what to do about her deteriorating condition. Neither did her family… About the Author With Instaread Summaries, you can get the summary of a book in 30 minutes or less. We read every chapter, summarize and analyze it for your convenience.

    The power of an artificial intelligence (AI) comes from its intelligence, not physical strength and laser guns. Humans steer the future not because we're the strongest or the fastest but because we're the smartest. When machines become smarter than humans, we'll be handing them the steering wheel. What promises—and perils—will these powerful machines present? Stuart Armstrong’s new book navigates these questions with clarity and wit.Can we instruct AIs to steer the future as we desire? What goals should we program into them? It turns out this question is difficult to answer! Philosophers have tried for thousands of years to define an ideal world, but there remains no consensus. The prospect of goal-driven, smarter-than-human AI gives moral philosophy a new urgency. The future could be filled with joy, art, compassion, and beings living worthwhile and wonderful lives—but only if we’re able to precisely define what a "good" world is, and skilled enough to describe it perfectly to a computer program.AIs, like computers, will do what we say—which is not necessarily what we mean. Such precision requires encoding the entire system of human values for an AI: explaining them to a mind that is alien to us, defining every ambiguous term, clarifying every edge case. Moreover, our values are fragile: in some cases, if we mis-define a single piece of the puzzle—say, consciousness—we end up with roughly 0% of the value we intended to reap, instead of 99% of the value.Though an understanding of the problem is only beginning to spread, researchers from fields ranging from philosophy to computer science to economics are working together to conceive and test solutions. Are we up to the challenge?A mathematician by training, Armstrong is a Research Fellow at the Future of Humanity Institute (FHI) at Oxford University. His research focuses on formal decision theory, the risks and possibilities of AI, the long term potential for intelligent life (and the difficulties of predicting this), and anthropic (self-locating) probability. Armstrong wrote Smarter Than Us at the request of the Machine Intelligence Research Institute, a non-profit organization studying the theoretical underpinnings of artificial superintelligence.

    Cyberia is an ideas-led, exuberant documentary written in 1994 about the converging strands of this new era, the empowerments of cyber-technology and the emergent hacker and cyber milieu.

    It is the history of who you are and how you came to be. It is unique to you, as it is to each of the 100 billion modern humans who have ever drawn breath. But it is also our collective story, because in every one of our genomes we each carry the history of our species births, deaths, disease, war, famine, migration, and a lot of sex. Since scientists first read the human genome in 2001, it has been subject to all sorts of claims, counterclaims, and myths. In fact, as Adam Rutherford explains, our genomes should be read not as instruction manuals, but as epic poems. DNA determines far less than we have been led to believe about us as individuals, but vastly more about us as a species. In this captivating journey through the expanding landscape of genetics, Adam Rutherford reveals what our genes now tell us about history, and what history tells us about our genes. From Neanderthals to murder, from redheads to race, dead kings to plague, evolution to epigenetics, this is a demystifying and illuminating new portrait of who we are and how we came to be."

    Reactions begins with the chemical formula almost everyone knows--the formula for water, H2O--a molecule with an "almost laughably simple chemical composition." But Peter Atkins shows that water is also rather miraculous--it is the only substance whose solid form is less dense than its liquid (hence ice floats in water)--and incredibly central to many chemical reactions, as it is an excellent solvent, being able to dissolve gases and many solids. Moreover, Atkins tells us that water is actually chemically aggressive, and can react with and destroy the compounds dissolved in it, and he also shows us what happens at the molecular level when water turns to ice--and when it melts. Moving beyond water, Atkins slowly builds up a toolkit of basic chemical processes, including precipitation (perhaps the simplest of all chemical reactions), combustion, reduction, corrosion, electrolysis, and catalysis. He then shows how these fundamental tools can be brought together in more complex processes such as photosynthesis, radical polymerization, vision, enzyme control, and synthesis. Peter Atkins is a world-renowned chemist who has taught at Oxford for decades and has an established track record as a popular science writer. In this crystal-clear, attractively illustrated, and insightful volume, Atkins treats the reader to a fantastic introductory tour--in just a few hundred colorful and lively pages.

    Czerski provides the tools to alter the way we see everything around us by linking ordinary objects and occurrences, like popcorn popping, coffee stains, and fridge magnets, to big ideas like climate change, the energy crisis, or innovative medical testing. She provides answers to vexing questions: How do ducks keep their feet warm when walking on ice? Why does it take so long for ketchup to come out of a bottle? Why does milk, when added to tea, look like billowing storm clouds? In an engaging voice at once warm and witty, Czerski shares her stunning breadth of knowledge to lift the veil of familiarity from the ordinary.

    Algorithms have made our lives more efficient, more entertaining, and, sometimes, better informed. At the same time, complex algorithms are increasingly violating the basic rights of individual citizens. Allegedly anonymized datasets routinely leak our most sensitive personal information; statistical models for everything from mortgages to college admissions reflect racial and gender bias. Meanwhile, users manipulate algorithms to "game" search engines, spam filters, online reviewing services, and navigation apps.Understanding and improving the science behind the algorithms that run our lives is rapidly becoming one of the most pressing issues of this century. Traditional fixes, such as laws, regulations and watchdog groups, have proven woefully inadequate. Reporting from the cutting edge of scientific research, The Ethical Algorithm offers a new approach: a set of principled solutions based on the emerging and exciting science of socially aware algorithm design. Michael Kearns and Aaron Roth explain how we can better embed human principles into machine code - without halting the advance of data-driven scientific exploration. Weaving together innovative research with stories of citizens, scientists, and activists on the front lines, The Ethical Algorithm offers a compelling vision for a future, one in which we can better protect humans from the unintended impacts of algorithms while continuing to inspire wondrous advances in technology.

    Call it the algebra oracle: By plugging in the right variables, GEEK LOGIK answers life’s most persistent questions. It covers Dating and Romance, Career and Finance, and everyday decisions like Should I get a tattoo? Can I still wear tight jeans? Is it time to see a therapist? How many beers should I have at the company picnic? How does it work? Take a simple issue that comes up once or twice a week: Should I call in sick? Fill in the variables honestly, such as D for doctor’s note (enter 1 for “no,†10 for “yes,†and 5 for “yes, but it’s a forgeryâ€), R for importance of job (1-10, with 10 being “personally responsible for Earth’s orbit around Sunâ€), Fj for how much fun you have at work (1-10, with 10 being “personal trainer for underwear modelsâ€), N for how much you need the money (1-10, with 10 being “I owe the mobâ€), then do the math, and voilà—if the product, Hooky, is greater than 1, enjoy your very own Ferris Bueller’s Day Off. Includes a pocket calculator so that prospective geeks can immediately solve the equation on the back cover: Should I buy this book?

    This volume of fifteen new, specially commissioned essays by notable journalists and scholars such as Rudy Rucker, Jim Holt, and Gregory Benford presents a series of speculations on the most radical but well-grounded ideas they can conceive, projecting the universe as it might be in the year 1,000,000 C.E. Their collective effort--first attempted by H. G. Wells in his 1893 essay "The Man of the Year Million"--is an exploration into a barely conceivable distant future, where the authors confront far-flung possibilities, at times bordering on philosophy of science. How would the galaxy look if it were redesigned for optimal energy use and maximized intelligence? What is a universe bereft of stars? Contributors include Amara D. Angelica, Catherine Asaro, Gregory Benford, Robert Bradbury, Sean M. Carroll, Anne Corwin, Dougal Dixon, Robin Hanson, Steven B. Harris, Jim Holt, Lisa Kaltenegger, Wil McCarthy, Rudy Rucker, Pamela Sargent, and George Zebrowski.

    David A Kessler has studied this question with regard to tobacco, food, and drugs. Over the course of these investigations, he identified one underlying mechanism common to a broad range of human suffering. This phenomenon—capture—is the process by which our attention is hijacked and our brains commandeered by forces outside our control.In Capture, Dr. Kessler considers some of the most profound questions we face as human beings: What are the origins of mental afflictions, from everyday unhappiness to addiction and depression—and how are they connected? Where does healing and transcendence fit into this realm of emotional experience?Analyzing an array of insights from psychology, medicine, neuroscience, literature, philosophy, and theology, Dr. Kessler deconstructs centuries of thinking, examining the central role of capture in mental illness and questioning traditional labels that have obscured our understanding of it. With a new basis for understanding the phenomenon of capture, he explores the concept through the emotionally resonant stories of both well-known and un-known people caught in its throes.The closer we can come to fully comprehending the nature of capture, Dr. Kessler argues, the better the chance to alleviate its deleterious effects and successfully change our thoughts and behavior Ultimately, Capture offers insight into how we form thoughts and emotions, manage trauma, and heal. For the first time, we can begin to understand the underpinnings of not only mental illness, but also our everyday worries and anxieties. Capture is an intimate and critical exploration of the most enduring human mystery of all: the mind.

    Join renowned neuroscientist David Eagleman for a journey into the questions at the mysterious heart of our existence. What is reality? Who are “you”? How do you make decisions? Why does your brain need other people? How is technology poised to change what it means to be human?  In the course of his investigations, Eagleman guides us through the world of extreme sports, criminal justice, facial expressions, genocide, brain surgery, gut feelings, robotics, and the search for immortality.  Strap in for a whistle-stop tour into the inner cosmos. In the infinitely dense tangle of billions of brain cells and their trillions of connections, something emerges that you might not have expected to see in there: you.

    With the Big Bang, it went from a state of unimaginable density to an all-encompassing cosmic fireball to a simmering fluid of matter and energy, laying down the seeds for everything from dark matter to black holes to one rocky planet orbiting a star near the edge of a spiral galaxy that happened to develop life. But what happens at the end of the story? In billions of years, humanity could still exist in some unrecognizable form, venturing out to distant space, finding new homes and building new civilizations. But the death of the universe is final. What might such a cataclysm look like? And what does it mean for us? Dr. Katie Mack has been contemplating these questions since she was eighteen, when her astronomy professor first informed her the universe could end at any moment, setting her on the path toward theoretical astrophysics. Now, with lively wit and humor, she unpacks them in The End of Everything, taking us on a mind-bending tour through each of the cosmos’ possible finales: the Big Crunch; the Heat Death; Vacuum Decay; the Big Rip; and the Bounce. In the tradition of Neil DeGrasse’s bestseller Astrophysics for People in a Hurry, Mack guides us through major concepts in quantum mechanics, cosmology, string theory, and much more, in a wildly fun, surprisingly upbeat ride to the farthest reaches of everything we know.

    While some marvel at these changes, envisioning consciousness downloaded into a computer or humans "beamed" Star Trek-style, others view them with horror, seeing monsters brooding in the machines. In How We Became Posthuman, N. Katherine Hayles separates hype from fact, investigating the fate of embodiment in an information age.Hayles relates three interwoven stories: how information lost its body, that is, how it came to be conceptualized as an entity separate from the material forms that carry it; the cultural and technological construction of the cyborg; and the dismantling of the liberal humanist "subject" in cybernetic discourse, along with the emergence of the "posthuman."Ranging widely across the history of technology, cultural studies, and literary criticism, Hayles shows what had to be erased, forgotten, and elided to conceive of information as a disembodied entity. Thus she moves from the post-World War II Macy Conferences on cybernetics to the 1952 novel Limbo by cybernetics aficionado Bernard Wolfe; from the concept of self-making to Philip K. Dick's literary explorations of hallucination and reality; and from artificial life to postmodern novels exploring the implications of seeing humans as cybernetic systems.Although becoming posthuman can be nightmarish, Hayles shows how it can also be liberating. From the birth of cybernetics to artificial life, How We Became Posthuman provides an indispensable account of how we arrived in our virtual age, and of where we might go from here.