It tells the story of the epic line of cell research that is right now coming together with discoveries that take us across the borders of biology into some of its most fascinating and bewildering frontiers, including cloning, genomic, molecular genetics, genetic engineering, and embryonic stem cells. This is a book that explores the moment when life science in the pursuit of medicine achieves the power to direct new steps in the evolution of the human body and spirit.The story is told through the lives of two amazing brothers: Stephen Heywood, a carpenter, who discovers he has A.L.S., a gradual, mysterious deterioration of the nervous system, also known as Lou Gehrig `s disease, and Jamie Heywood, an engineer who quits his lucrative job to start a foundation where he obsessively works with cutting-edge scientists in a race to find a cure. Through this remarkable journey with a family in crisis, we are given an overview of the various gene therapies that are still on the horizon, capable of potentially bringing back those suffering from such neurological diseases as A.L.S., Alzheimer's, Parkinson's, and other various disorders of the brain. Through the translucent prose of Jonathan Weiner, we experience not only the passion and torment of the Heywoods, but we learn a vast amount about the groundbreaking technologies that may one day save our own lives and certainly change the way we live them.

    The inspiring story of turning stolen years into life-changing hope not only for her but two destitute children will bring tears to the reader as he identifies with her feelings of insecurity and fear. The timeless theme of God's faithfulness-the stuff out of which God brings redemption-will leave the reader riveted to the pages of this book. "Children of Dreams" is more than an adoption story set in the remotest regions of the planet. Facing insurmountable odds-communist blockades, life-threatening illness, betrayal and deceit-Lorilyn Roberts' courage and determination never to give up will touch the reader. Despair transformed into heavenly joy and evil overcome by God's redemptive love will inspire even the most skeptical to believe in miracles. "Children of Dreams" resonates with Biblical truth at a deep level and in a sense is everyone's story. Ms. Roberts is intimately familiar with adoption, having also been adopted as a child, and is able to present the spirit of adoption, as never before captured, in this tender tale. Comparing the adoption of her daughters to her adoption by the heavenly Father throughout the story flows naturally.

    He often came across as a man possessed, holding forth on culture and politics while mixing in personal revelations – all with mercurial, tongue-twisting intensity as he inhabited and shed one character after another with lightning speed.But as Dave Itzkoff shows in this revelatory biography, Williams’s comic brilliance masked a deep well of conflicting emotions and self-doubt, which he drew upon in his comedy and in celebrated films like Dead Poets Society; Good Morning, Vietnam; The Fisher King; Aladdin; and Mrs. Doubtfire, where he showcased his limitless gift for improvisation to bring to life a wide range of characters. And in Good Will Hunting he gave an intense and controlled performance that revealed the true range of his talent.Itzkoff also shows how Williams struggled mightily with addiction and depression – topics he discussed openly while performing and during interviews – and with a debilitating condition at the end of his life that affected him in ways his fans never knew. Drawing on more than a hundred original interviews with family, friends, and colleagues, as well as extensive archival research, Robin is a fresh and original look at a man whose work touched so many lives.

    Newly single and ready to embrace life, George was excited to turn fifty. It would be a welcome new phase in his life, a chance to say goodbye to a decade that included a kidney transplant and a divorce. But when he looked around a room full of his childhood friends, all gathered to celebrate his birthday, many now bald or overweight, it suddenly hit him that he was old. What happened? And more importantly, what was he going to do about it? George learns the hard way that when you turn 50, everything changes. You pull a muscle in your sleep. You avoid mirrors at all costs, and always, always wear a robe. You have to schedule an appointment to have sex. You have to dye your hair and buy a bathtub with a door. As George learns to embrace life after fifty, he invites readers into his world, sharing the ups and downs of getting older—from his relationship with a much younger woman to a bizarre session with a pet psychic, to a trip behind-the-scenes at his tumultuous two years at Lopez Tonight, to an intimate look at his sacred ground, the golf course—and, for the first time, he reveals in moving detail, the story of the battle for his life against kidney disease.   I’m Not Gonna Lie  will make you laugh at yourself, cry about yourself, and look at turning fifty in a way you never would’ve imagined—through the eyes of George Lopez.

    Until one day they all flood back in horrible detail.When television producers approached Alan Cumming to appear on a popular celebrity genealogy show, he hoped to solve the mystery of his maternal grandfather's disappearance that had long cast a shadow over his family. But this was not the only mystery laid before Alan.Alan grew up in the grip of a man who held his family hostage, someone who meted out violence with a frightening ease, who waged a silent war with himself that sometimes spilled over onto everyone around him. That man was Alex Cumming, Alan's father, whom Alan had not seen or spoken to for more than a decade when he reconnected just before filming for Who Do You Think You Are? began. He had a secret he had to share, one that would shock his son to his very core and set into motion a journey that would change Alan's life forever.With ribald humor, wit, and incredible insight, Alan seamlessly moves back and forth in time, integrating stories from his childhood in Scotland and his experiences today as the celebrated actor of film, television, and stage. At times suspenseful, at times deeply moving, but always incredibly brave and honest, Not My Father's Son is a powerful story of embracing the best aspects of the past and triumphantly pushing the darkness aside.

    The warm memoir follows the lives of brothers Deepak and Sanjiv Chopra, who left a comfortable life in post-war India to develop their professional skills in America, both achieving success following in their father’s footsteps as healers—Deepak as bestselling author, physician, and speaker, and Sanjiv as professor of medicine and faculty dean for continuing medical education at Harvard Medical School.

    The phrase he hates most is "throw like a girl," so he teaches them to climb trees and play ball. But when he discovers a lump in five-year-old Zoë's midsection as she sits on his lap at a Chicago Cubs game, everything changes. Surgery, sleepless nights, treatments, a drumbeat of worry. Even as the family moves to New York and Zoë starts kindergarten, they must navigate a new normal: school and soccer games and hot chocolates in cafés regularly interrupted by anxious visits to the hospital. And Elisha is forced to balance his desire to be a protective parent—even as he encourages his girls to take risks—against the increasing helplessness he feels for his child's well-being, and his own. With the observant eye of an artist and remarkable humor, Elisha writes about what it took for him and his wife to preserve a sense of normalcy and joy in their daughters' lives; how the family emerged from this experience profoundly changed, but healed and whole; how we are all transformed by the fear and hope we feel for those we love.From the Hardcover edition.

    Last year, he made the stunning announcement that he had been diagnosed with stage four pancreatic cancer. What followed was an incredible outpouring of love and kindness. Social media was flooded with messages of support, and the Jeopardy! studio received boxes of cards and letters offering guidance, encouragement, and prayers.For over three decades, Trebek had resisted countless appeals to write a book about his life. Yet he was moved so much by all the goodwill, he felt compelled to finally share his story. “I want people to know a little more about the person they have been cheering on for the past year,” he writes in The Answer Is…: Reflections on My Life.The book combines illuminating personal anecdotes with Trebek’s thoughts on a range of topics, including marriage, parenthood, education, success, spirituality, and philanthropy. Trebek also addresses the questions he gets asked most often by Jeopardy! fans, such as what prompted him to shave his signature mustache, his insights on legendary players like Ken Jennings and James Holzhauer, and his opinion of Will Ferrell’s Saturday Night Live impersonation. The book uses a novel structure inspired by Jeopardy!, with each chapter title in the form of a question, and features dozens of never-before-seen photos that candidly capture Trebek over the years.This wise, charming, and inspiring book is further evidence why Trebek has long been considered one of the most beloved and respected figures in entertainment.

    Pamela Grim has delivered babies, treated heart attacks, saved car accident victims, comforted the dying, and consoled the living who were left behind. She has worked all over the world, caring for victims of gang life in America's inner cities, victims of the war in Bosnia, poverty-stricken patients in Nigeria, and bank presidents in the United States. Relating these rich and varied experiences with compelling prose, Dr. Grim takes readers into the E.R. and lets them experience first-hand what it takes to make split-second, life-and-death decisions in the course of an average day. And with unflinching honesty, she conveys what it's like to be a caring physician with one of the most demanding, exhilarating, frustrating, and rewarding jobs in the world.

    Now she offers her most personal and most deeply felt memoir yet as she embarks on her greatest, most terrifying, most rewarding endeavor of all….A good mother, writes Jeanne Marie Laskas in her latest report from Sweetwater Farm, would have bought a house in the suburbs with a cul-de-sac for her kids to ride bikes around instead of a ramshackle house in the middle of nowhere with a rooster. With the wryly observed self-doubt all mothers and mothers-to-be will instantly recognize, Laskas offers a poignant and laugh-out-loud-funny meditation on that greatest–and most impossible–of all life’s journeys: motherhood.What is it, she muses, that’s so exhausting about being a mom? You’d think raising two little girls would be a breeze compared to dealing with the barely controlled anarchy of “attack” roosters, feuding neighbors, and a scheme to turn sheep into lawn mowers on the fifty-acre farm she runs with her bemused husband Alex. But, as any mother knows, you’d be wrong.From struggling with the issues of race and identity as she raises two children adopted from China to taking her daughters to the mall for their first manicures, Jeanne Marie captures those magic moments that make motherhood the most important and rewarding job in the world–even if it’s never been done right. For, as she concludes in one of her three a.m. worry sessions, feeling like a bad mother is the only way to know you’re doing your job.Whether confronting Sasha’s language delay, reflecting on Anna’s devotion to a creepy backwards-running chicken, feeling outclassed by the fabulous homeroom moms, or describing the rich, secret language each family shares, these candid observations from the front lines of parenthood are filled with love and laughter–and radiant with the tough, tender, and timeless wisdom only raising kids can teach us.

    There’s also Felicia Day—violinist, filmmaker, Internet entrepreneur, compulsive gamer, hoagie specialist, and former lonely homeschooled girl who overcame her isolated childhood to become the ruler of a new world... or at least semi-influential in the world of Internet Geeks and Goodreads book clubs.After growing up in the south where she was "home-schooled for hippie reasons", Felicia moved to Hollywood to pursue her dream of becoming an actress and was immediately typecast as a crazy cat-lady secretary. But Felicia’s misadventures in Hollywood led her to produce her own web series, own her own production company, and become an Internet star.Felicia’s short-ish life and her rags-to-riches rise to Internet fame launched her career as one of the most influential creators in new media. Now, Felicia’s strange world is filled with thoughts on creativity, video games, and a dash of mild feminist activism—just like her memoir.Hilarious and inspirational, You’re Never Weird on the Internet (Almost) is proof that everyone should embrace what makes them different and be brave enough to share it with the world, because anything is possible now—even for a digital misfit.

    Don't, for instance, pass the Fryemont Inn when the windows are open--not unless you plan to come inside and enjoy fresh-baked rolls, gourmet cooking, and an owner who is as warm and inviting as the food. She's just one of the friendly faces you'll meet in Bryson City Secrets.Told with winsome humor and deep affection, Bryson City Secrets is a story-lover's delight, continuing Dr. Walt Larimore's reminiscences of his early years of country medical practice. Pull up a chair and feast on this rich fare of Smoky Mountain personalities, highland wisdom, and all the tears, laughter, tenderness, faith, courage, and misadventures of small-town life.

    It has been out of print since at least 1977 and was never published outside the USA.

    With soaring prose that celebrates a resurgent American Midwest, Shortest Way Home narrates the heroic transformation of a “dying city” (Newsweek) into nothing less than a shining model of urban reinvention.Interweaving two narratives—that of a young man coming of age and a town regaining its economic vitality—Buttigieg recounts growing up in a Rust Belt city, amid decayed factory buildings and the steady soundtrack of rumbling freight trains passing through on their long journey to Chicagoland. Inspired by John F. Kennedy’s legacy, Buttigieg first left northern Indiana for red-bricked Harvard and then studied at Oxford as a Rhodes Scholar, before joining McKinsey, where he trained as a consultant—becoming, of all things, an expert in grocery pricing. Then, Buttigieg defied the expectations that came with his pedigree, choosing to return home to Indiana and responding to the ultimate challenge of how to revive a once-great industrial city and help steer its future in the twenty-first century.Elected at twenty-nine as the nation’s youngest mayor, Pete Buttigieg immediately recognized that “great cities, and even great nations, are built through attention to the everyday.” As Shortest Way Home recalls, the challenges were daunting—whether confronting gun violence, renaming a street in honor of Martin Luther King Jr., or attracting tech companies to a city that had appealed more to junk bond scavengers than serious investors. None of this is underscored more than Buttigieg’s audacious campaign to reclaim 1,000 houses, many of them abandoned, in 1,000 days and then, even as a sitting mayor, deploying to serve in Afghanistan as a Navy officer. Yet the most personal challenge still awaited Buttigieg, who came out in a South Bend Tribune editorial, just before being reelected with 78 percent of the vote, and then finding Chasten Glezman, a middle-school teacher, who would become his partner for life.While Washington reels with scandal, Shortest Way Home, with its graceful, often humorous, language, challenges our perception of the typical American politician. In chronicling two once-unthinkable stories—that of an Afghanistan veteran who came out and found love and acceptance, all while in office, and that of a revitalized Rust Belt city no longer regarded as “flyover country”—Buttigieg provides a new vision for America’s shortest way home.

    It's a bizarre parade of humanity looking for help -- in the one place they know they can find it.Welcome to the frontline trenches of medicine: the emergency room of the legendary Bellevue Hospital. Here, an army of doctors and nurses faces the onslaught of young and old, rich and ragged, sick and dying. All day, all night. All year.This is their story -- an around-the-clock drama of the unexpected: a crane falling on a hapless pedestrian; a crazed executive wearing two-thirds of a three-piece suit; a pretty paralegal aide struggling with an on-the-job cocaine overdose; a trauma victim of an East River helicopter crash clinging to life. It's terrifying, tragic, triumphant ... and true.