At fifty, Betty is unemployed, divorced and penniless, but with her stunningly beautiful niece Lori, she opens Take A Chance Tours, a Chicago-based company specializing in gaming destinations. Betty quickly becomes close friends with Tillie, the perky, effervescent bus driver who happens to be an ex-con. As soon as the tour bus arrives at Moose Lake Bay Resort and Casino in northern Minnesota, Betty and her driver Tillie, discover a dead body in the locked bathroom of their motor coach. The 350-pound corpse is riddled with stab wounds. With Tillie and Lori's help, Betty puts her amateur sleuth ability to work and searches for the killer.