After 3.8 billion years humankind is about to start evolving by new rules...From leading geopolitical expert and technology futurist Jamie Metzl comes a groundbreaking exploration of the many ways genetic-engineering is shaking the core foundations of our lives -- sex, war, love, and death.At the dawn of the genetics revolution, our DNA is becoming as readable, writable, and hackable as our information technology. But as humanity starts retooling our own genetic code, the choices we make today will be the difference between realizing breathtaking advances in human well-being and descending into a dangerous and potentially deadly genetic arms race.Enter the laboratories where scientists are turning science fiction into reality. Look towards a future where our deepest beliefs, morals, religions, and politics are challenged like never before and the very essence of what it means to be human is at play. When we can engineer our future children, massively extend our lifespans, build life from scratch, and recreate the plant and animal world, should we?

    He wrote vast volumes about animals. He described them, classified them, told us where and how they live and how they develop in the womb or in the egg. He founded a science. It can even be said that he founded science itself.In The Lagoon, acclaimed biologist Armand Marie Leroi recovers Aristotle’s science. He revisits Aristotle’s writings and the places where he worked. He goes to the eastern Aegean island of Lesbos to see the creatures that Aristotle saw, where he saw them. He explores Aristotle’s observations, his deep ideas, his inspired guesses—and the things he got wildly wrong. He shows how Aristotle’s science is deeply intertwined with his philosophical system and reveals that he was not only the first biologist, but also one of the greatest.The Lagoon is both a travelogue and a study of the origins of science. And it shows how a philosopher who lived almost two millennia ago still has so much to teach us today.

    By turns humorous and moving, Tales from Both Sides of the Brain interweaves Gazzaniga’s scientific achievements with his reflections on the challenges and thrills of working as a scientist.

    The fascinating story of the golden period from the revelation of the double helix of DNA to the cracking of the genetic code and first glimpses of gene regulation is told largely in the words of the main players, all of whom Judson interviewed extensively. The result is a book widely regarded as the best history of recent biological science yet published.This commemorative edition, honoring the memory of the author who died in 2011, contains essays by his daughter Olivia Judson, Matthew Meselson, and Mark Ptashne and an obituary by Jason Pontin. It contains all the content added to previous editions, including essays on some of the principal historical figures involved, such as Rosalind Franklin, and a sketch of the further development of molecular biology in the era of recombinant DNA.

    Hardy, in the years before World War I. Through their eyes the reader is taken on a journey through numbers theory. Ramanujan would regularly telescope 12 steps of logic into two - the effect is said to be like Dr Watson in the train of some argument by Sherlock Holmes. The language of symbols and infinitely large (and small) regions of mathematics should be rendered with clarity for the general reader.

    Breslin comes from the same Queens streets as mob bosses John Gotti and Vito Genovese. But even they couldn't match Kaplan in crime—and neither could anybody else.In his inimitable New York voice, Breslin, "the city's steadiest and most accurate chronicler" (Tom Robbins, Village Voice), gives us a look through the keyhole at the people and places that define the mafia—characters like Sammy "The Bull" Gravano, Gaspipe Casso (named for his weapon of choice), Thomas "Three-Finger Brown" Lucchese, and Jimmy "The Clam" Eppolito, interwoven with the good rat himself, Burt Kaplan of Bensonhurst, the star witness in the recent trial of two New York City detectives indicted for acting as hit men in eight gangland executions.Breslin takes us to the old-time hangouts like Pep McGuire's, the legendary watering hole where reporters and gangsters (all hailing from the same working-class neighborhoods) rubbed elbows and traded stories; the dog-fight circles and body dumps at Ozone Park; and the back room at Midnight Rose's candy store, where Murder, Inc., hired and fired.Most compelling of all, Breslin captures the moments in which the Mafia was made and broken—Breslin was there the night John Gotti celebrated his acquittal at his Ravenite Social Club on Mulberry, having bribed his way to inno­cence only to incite the wrath of the FBI, who would later crush Gotti and others with the full force of the RICO laws.As in his unforgettable novel The Gang That Couldn't Shoot Straight, Breslin brings together these real-life and long-forgotten Mafia stories to brilliantly create a sharp-eyed portrait of the mob as it lived and breathed, as it sounded and survived.

    In the spring of 1940, the aspiring but unknown writer Albert Camus and budding scientist Jacques Monod were quietly pursuing ordinary, separate lives in Paris. After the German invasion and occupation of France, each joined the Resistance to help liberate the country from the Nazis, ascended to prominent, dangerous roles, and were very lucky to survive. After the war and through twists of circumstance, they became friends, and through their passionate determination and rare talent, they emerged as leading voices of modern literature and biology, each receiving the Nobel Prize in their respective fields. Drawing upon a wealth of previously unpublished and unknown material gathered over several years of research, Brave Genius tells the story of how each man endured the most terrible episode of the twentieth century and then blossomed into extraordinarily creative and engaged individuals. It is a story of the transformation of ordinary lives into exceptional lives by extraordinary events--of courage in the face of overwhelming adversity, the flowering of creative genius, deep friendship, and of profound concern for and insight into the human condition.

    Its job is to protect us from cancer. This gene--known simply as p53--constantly scans our cells to ensure that when they grow and divide as part of the routine maintenance of our bodies, they do so without mishap. If a cell makes a mistake in copying its DNA during the process of division, p53 stops it in its tracks, sending in the repair team before allowing the cell to carry on dividing. If the mistake is irreparable and the rogue cell threatens to grow out of control (as happens in cancer), p53 commands the cell to commit suicide. Cancer cannot develop unless p53 itself is damaged or handicapped by some other fault in the system. Not surprisingly, p53 is the most studied single gene in history. p53: The Gene that Cracked the Cancer Code tells the story of the discovery of the gene and of medical science's mission to unravel its mysteries and get to the heart of what happens in our cells when they turn cancerous. Through the personal accounts of key researchers, the book reveals the excitement of the hunt for new cures--the hype, the enthusiasm, the lost opportunities, the blind alleys and the thrilling breakthroughs. As the long-anticipated revolution in cancer treatment tailored to each individual patient's symptoms starts to take off at last, p53 is at the cutting edge. This is a timely tale of scientific discovery and advances in our understanding of a disease that still affects more than one in three of us at some point in our lives.

    Robert Oppenheimer, Freeman Dyson has composed an autobiography unlike any other. Dyson evocatively conveys the thrill of a deep engagement with the world-be it as scientist, citizen, student, or parent. Detailing a unique career not limited to his groundbreaking work in physics, Dyson discusses his interest in minimizing loss of life in war, in disarmament, and even in thought experiments on the expansion of our frontiers into the galaxies.

    It’s so bound up with our deepest feelings that emotional trauma causes it to change shape.Practising cardiologist Sandeep Jauhar beautifully weaves his own experiences with the defining discoveries of the past to tell the story of our most vital organ. He looks at some of the pioneers who risked their careers and their patients’ lives to better understand the heart. People like Daniel Hale Williams, who performed the world’s first documented heart surgery, and Wilson Greatbatch, who accidentally invented the pacemaker.Amid gripping scenes from the operating theatre, Jauhar interweaves stories about the patients he’s treated with the moving tale of his family’s own history of heart problems, from his grandfather’s sudden death in India – an event that sparked his life-long obsession – to the ominous signs of how he himself might die.He also confronts the limits of medical technology and argues that future progress will be determined more by how we choose to live rather than by any device we invent.

    During his life he created numerous works of art and kept voluminous notebooks that detailed his artistic and intellectual pursuits.The collection of writings and art in this magnificent book are drawn from his notebooks. The book organizes his wide range of interests into subjects such as human figures, light and shade, perspective and visual perception, anatomy, botany and landscape, geography, the physical sciences and astronomy, architecture, sculpture, and inventions. Nearly every piece of writing throughout the book is keyed to the piece of artwork it describes.The writing and art is selected by art historian H. Anna Suh, who provides fascinating commentary and insight into the material, making Leonardo's Notebooks an exquisite single-volume compendium celebrating his enduring genius.

    Though she kept her private life a mystery, for some years Agatha had secretly written her autobiography, and when it was published after her death, millions of her fans agreed - this was her best story!From early childhood at the end of the 19th century, through two marriages and two World Wars, and her experiences both as a writer and on archaeological expeditions with her second husband, Max Mallowan, this book reveals the true genius of her legendary success with real passion and openness.

    A defiant atheist, Chapman is confronted not only by the fundamentalist beliefs that continue to banish the theory of evolution but by his own spiritual malaise as the outward journey becomes an inward quest, a tragicomic "accidental memoir"."First there was Charles Darwin, two yards long and nobody's fool. Then there was his son, my great-grandfather, Sir Francis Darwin, an eminent botanist. Then came my grandmother Frances, a modest poet who spent a considerable amount of time in rest-homes for depression From her issued my beloved mother, Clare, who was extremely short, failed to complete medical school, and eventually became an alcoholic. Then we get down to me. I'm in the movie business."Trials of the Monkey combines travel writing and reportage, as Chapman records his encounters in the South, with history and the accidental memoir of a man full of mid-life doubts in a genre-breaking first book that is darkly funny, provocative and poignant.

    In this sensational and macabre story, we meet the surgeon who counted not only luminaries Benjamin Franklin, Lord Byron, Adam Smith, and Thomas Gainsborough among his patients but also “resurrection men” among his close acquaintances. A captivating portrait of his ruthless devotion to uncovering the secrets of the human body, and the extraordinary lengths to which he went to do so—including body snatching, performing pioneering medical experiments, and infecting himself with venereal disease—this rich historical narrative at last acknowledges this fascinating man and the debt we owe him today.

    The authors bring to life Darwin's reckless student days in Cambridge, his epic five-year voyage on the Beagle, and his grueling struggle to develop his theory of evolution.Adrian Desmond and James Moore's gripping narrative reveals the great personal cost to Darwin of pursuing inflammatory truths—telling the whole story of how he came to his epoch-making conclusions.