One sought to discover a new planet. Another—an adventuresome female astronomer—fought to prove that science was not anathema to femininity. And a young, megalomaniacal inventor, with the tabloid press fast on his heels, sought to test his scientific bona fides and light the world through his revelations. David Baron brings to three-dimensional life these three competitors—James Craig Watson, Maria Mitchell, and Thomas Edison—and thrillingly re-creates the fierce jockeying of nineteenth-century American astronomy. With spellbinding accounts of train robberies and Indian skirmishes, the mythologized age of the last days of the Wild West comes alive as never before. A magnificent portrayal of America’s dawn as a scientific superpower, American Eclipse depicts a young nation that looked to the skies to reveal its towering ambition and expose its latent genius.

    There have been exhilarating highs and devastating lows, but his love for the practice of neurosurgery has never wavered. Following the publication of his celebrated New York Times bestseller Do No Harm, Marsh retired from his full-time job in England to work pro bono in Ukraine and Nepal. In Admissions, he describes the difficulties of working in these troubled, impoverished countries and the further insights it has given him into the practice of medicine. Marsh also faces up to the burden of responsibility that can come with trying to reduce human suffering. Unearthing memories of his early days as a medical student and the experiences that shaped him as a young surgeon, he explores the difficulties of a profession that deals in probabilities rather than certainties and where the overwhelming urge to prolong life can come at a tragic cost for patients and those who love them. Reflecting on what forty years of handling the human brain has taught him, Marsh finds a different purpose in life as he approaches the end of his professional career and a fresh understanding of what matters to us all in the end.

    How did the table fork acquire a fourth tine?  What advantage does the Phillips-head screw have over its single-grooved predecessor? Why does the paper clip look the way it does? What makes Scotch tape Scotch?   In this delightful book Henry Petroski takes a microscopic look at artifacts that most of us count on but rarely contemplate, including such icons of the everyday as pins, Post-its, and fast-food "clamshell" containers.  At the same time, he offers a convincing new theory of technological innovation as a response to the perceived failures of existing products—suggesting that irritation, and not necessity, is the mother of invention.

    This early-20th-century battle centers on one man: Tom Anderson, the undisputed czar of the city's Storyville vice district, who fights desperately to keep his empire intact as it faces onslaughts from all sides. Surrounding him are the stories of flamboyant prostitutes, crusading moral reformers, dissolute jazzmen, ruthless Mafiosi, venal politicians, and one extremely violent serial killer, all battling for primacy in a wild and wicked city unlike any other in the world.

    From Mary, Queen of Scots, trapped by her own code, to the Navajo Code Talkers who helped the Allies win World War II, to the incredible (and incredibly simple) logisitical breakthrough that made Internet commerce secure, The Code Book tells the story of the most powerful intellectual weapon ever known: secrecy.Throughout the text are clear technical and mathematical explanations, and portraits of the remarkable personalities who wrote and broke the world’s most difficult codes. Accessible, compelling, and remarkably far-reaching, this book will forever alter your view of history and what drives it. It will also make you wonder how private that e-mail you just sent really is.

    For two decades, historian Alice Dreger has led a life of extraordinary engagement, combining activist service to victims of unethical medical research with defense of scientists whose work has outraged identity politics activists. With spirit and wit, Dreger offers in Galileo’s Middle Finger an unforgettable vision of the importance of rigorous truth seeking in today’s America, where both the free press and free scholarly inquiry struggle under dire economic and political threats.This illuminating chronicle begins with Dreger’s own research into the treatment of people born intersex (once called hermaphrodites). Realization of the shocking surgical and ethical abuses conducted in the name of “normalizing” intersex children’s gender identities moved Dreger to become an internationally recognized patient rights’ activist. But even as the intersex rights movement succeeded, Dreger began to realize how some fellow progressive activists were employing lies and personal attacks to silence scientists whose data revealed uncomfortable truths about humans. In researching one such case, Dreger suddenly became the target of just these kinds of attacks.Troubled, she decided to try to understand more—to travel the country to ferret out the truth behind various controversies, to obtain a global view of the nature and costs of these battles. Galileo’s Middle Finger describes Dreger’s long and harrowing journeys between the two camps for which she felt equal empathy: social justice activists determined to win and researchers determined to put hard truths before comfort. Ultimately what emerges is a lesson about the intertwining of justice and of truth—and a lesson of the importance of responsible scholars and journalists to our fragile democracy.

    He boarded a friend’s yacht, sailed into the calm blue waters of Long Island Sound, and--poof!--disappeared. He would not be heard from again for five days. What happened during those five days, and in the days and weeks that followed, was so incredible that, even when the truth was finally revealed, many Americans simply would not believe it.The President Is a Sick Man details an extraordinary but almost unknown chapter in American history: Grover Cleveland’s secret cancer surgery and the brazen political cover-up by a politician whose most memorable quote was “Tell the truth.” When an enterprising reporter named E. J. Edwards exposed the secret operation, Cleveland denied it. The public believed the “Honest President,” and Edwards was dismissed as “a disgrace to journalism.” The facts concerning the disappearance of Grover Cleveland that summer were so well concealed that even more than a century later a full and fair account has never been published. Until now.

    Bell ruling made government sterilization of "undesirable" citizens the law of the land. New York Times bestselling author Adam Cohen tells the story in Imbeciles of one of the darkest moments in the American legal tradition: the Supreme Court's decision to champion eugenic sterilization for the greater good of the country. In 1927, when the nation was caught up in eugenic fervor, the justices allowed Virginia to sterilize Carrie Buck, a perfectly normal young woman, for being an "imbecile." It is a story with many villains, from the superintendent of the Dickensian Virginia Colony for Epileptics and Feebleminded who chose Carrie for sterilization to the former Missouri agriculture professor and Nazi sympathizer who was the nation's leading advocate for eugenic sterilization. But the most troubling actors of all were the eight Supreme Court justices who were in the majority--including William Howard Taft, the former president; Louis Brandeis, the legendary progressive; and Oliver Wendell Holmes, Jr., America's most esteemed justice, who wrote the decision urging the nation to embark on a program of mass eugenic sterilization

    In addition to offering a clear-eyed explanation of the root causes of this insidious and entrenched bias and laying out its effects, she suggests concrete steps we can take to cure it.

    When he emerged three years later, the summation of his efforts only hinted at what he'd experienced in one of the most dangerous regions on earth. Armed with an astonishing collection of zoological specimens, Du Chaillu leapt from the physical challenges of the jungle straight into the center of the biggest issues of the time--the evolution debate, racial discourse, the growth of Christian fundamentalism--and helped push each to unprecedented intensities. He experienced instant celebrity, but with that fame came whispers--about his past, his credibility, and his very identity--which would haunt the young man. Grand in scope, immediate in detail, and propulsively readable, Between Man and Beast brilliantly combines Du Chaillu's personal journey with the epic tale of a world hovering on the sharp edge of transformation.

    An Edible History of Humanity is a pithy, entertaining account of how a series of changes—caused, enabled, or influenced by food—has helped to shape and transform societies around the world. The first civilizations were built on barley and wheat in the Near East, millet and rice in Asia, and corn and potatoes in the Americas. Why farming created a strictly ordered social hierarchy in contrast to the loose egalitarianism of hunter-gatherers is, as Tom Standage reveals, as interesting as the details of the complex cultures that emerged, eventually interconnected by commerce. Trade in exotic spices in particular spawned the age of exploration and the colonization of the New World. Food's influence over the course of history has been just as prevalent in modern times. In the late eighteenth century, Britain's solution to food shortages was to industrialize and import food rather than grow it. Food helped to determine the outcome of wars: Napoleon's rise and fall was intimately connected with his ability to feed his vast armies. In the twentieth century, Communist leaders employed food as an ideological weapon, resulting in the death by starvation of millions in the Soviet Union and China. And today the foods we choose in the supermarket connect us to global debates about trade, development, the environment, and the adoption of new technologies. Encompassing many fields, from genetics and archaeology to anthropology and economics—and invoking food as a special form of technology—An Edible History of Humanity is a fully satisfying discourse on the sweep of human history.

    Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings? A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.

    On 29 March 1849, the ten-year-old Maharajah of the Punjab was ushered into the magnificent Mirrored Hall at the centre of the great Fort in Lahore. There, in a public ceremony, the frightened but dignified child handed over to the British East India Company in a formal Act of Submission to Queen Victoria not only swathes of the richest land in India, but also arguably the single most valuable object in the subcontinent: the celebrated Koh-i Noor diamond. The Mountain of Light. The history of the Koh-i-Noor that was then commissioned by the British may have been one woven together from gossip of Delhi Bazaars, but it was to be become the accepted version. Only now is it finally challenged, freeing the diamond from the fog of mythology which has clung to it for so long. The resulting history is one of greed, murder, torture, colonialism and appropriation through an impressive slice of south and central Asian history. It ends with the jewel in its current controversial setting: in the crown of Queen Elizabeth the Queen Mother. Masterly, powerful and erudite, this is history at its most compelling and invigorating.

    But these tiny insects, once merely a seasonal annoyance, now are capturing headlines worldwide as new information emerges about the diseases they carry, their migratory population, and their growing resistance to pesticides.Harvard professor Andrew Spielman has dedicated his life to understanding this insect, a passion that makes him the perfect guide to their amazing world and the perfect author of this lively, accessible book that offers an intriguing and horrifying mosquito-eye view of nature and man. He explains where mosquitoes breed, and how they die, showing us their natural foes and man-made enemies while explaining the myriad diseases they bring to all corners of the world. Spielman offers colorful examples of how the mosquito has insinuated itself into human history, from the defeat of Sir Francis Drake's fleet to the death of thousands of Frenchmen working on the Panama Canal to the recent widespread West Nile panic in New York City. Filled with little-known facts and illuminating anecdotes that bring this tiny being into larger focus, Mosquito offers fascinating, alarming, and convincing evidence that the sooner we get to know this little creature, the better off we'll be.

    Sparking the idea for this book was Carroll’s visit to the spot where Abraham Lincoln’s son was saved by the brother of Lincoln’s assassin. Carroll wondered, How many other unmarked places are there where intriguing events have unfolded and that we walk past every day, not realizing their significance? To answer that question, Carroll ultimately trekked to every region of the country -- by car, train, plane, helicopter, bus, bike, and kayak and on foot. Among the things he learned: *Where in North America the oldest sample of human DNA was discovered * Where America’s deadliest maritime disaster took place, a calamity worse than the fate of the Titanic *Which virtually unknown American scientist saved hundreds of millions of lives *Which famous Prohibition agent was the brother of a notorious gangster *How a 14-year-old farm boy’s brainstorm led to the creation of television Featured prominently in Here Is Where are an abundance of firsts (from the first use of modern anesthesia to the first cremation to the first murder conviction based on forensic evidence); outrages (from riots to massacres to forced sterilizations); and breakthroughs (from the invention, inside a prison, of a revolutionary weapon; to the recovery, deep in the Alaskan tundra, of a super-virus; to the building of the rocket that made possible space travel). Here Is Where is thoroughly entertaining, but it’s also a profound reminder that the places we pass by often harbor amazing secrets and that there are countless other astonishing stories still out there, waiting to be found.