The Epigenetics Revolution


Nessa Carey - 2011
    The Human Genome Project finished sequencing human DNA. It seemed it was only a matter of time until we had all the answers to the secrets of life on this planet. The cutting-edge of biology, however, is telling us that we still don't even know all of the questions. How is it that, despite each cell in your body carrying exactly the same DNA, you don't have teeth growing out of your eyeballs or toenails on your liver? How is it that identical twins share exactly the same DNA and yet can exhibit dramatic differences in the way that they live and grow? It turns out that cells read the genetic code in DNA more like a script to be interpreted than a mould that replicates the same result each time. This is epigenetics and it's the fastest-moving field in biology today. The Epigenetics Revolution traces the thrilling path this discipline has taken over the last twenty years. Biologist Nessa Carey deftly explains such diverse phenomena as how queen bees and ants control their colonies, why tortoiseshell cats are always female, why some plants need a period of cold before they can flower, why we age, develop disease and become addicted to drugs, and much more. Most excitingly, Carey reveals the amazing possibilities for humankind that epigenetics offers for us all - and in the surprisingly near future.

End of the Megafauna: The Fate of the World's Hugest, Fiercest, and Strangest Animals


Ross D.E. MacPhee - 2018
    These great beasts, or “megafauna,” lived on every habitable continent and on many islands. With a handful of exceptions, all are now gone.What caused the disappearance of these prehistoric behemoths? No one event can be pinpointed as a specific cause, but several factors may have played a role. Paleomammalogist Ross D. E. MacPhee explores them all, examining the leading extinction theories, weighing the evidence, and presenting his own conclusions. He shows how theories of human overhunting and catastrophic climate change fail to account for critical features of these extinctions, and how new thinking is needed to elucidate these mysterious losses.Along the way, we learn how time is determined in earth history; how DNA is used to explain the genomics and phylogenetic history of megafauna—and how synthetic biology and genetic engineering may be able to reintroduce these giants of the past. Until then, gorgeous four-color illustrations by Peter Schouten re-create these megabeasts here in vivid detail.