Provies basic theoretical discussions of the principles of biopharmaceutics and pharmacokinetics, along with illustrative examples and practice problems and solutions to help the student gain skill in practical problem solving.

    A vast and powerful alliance of thousands of farming hamlets and nearly 100 spectacular towns integrated the region through economic and religious ties, and the whole system was interconnected with hundreds of miles of roads. It took these Anasazi farmers more than seven centuries to lay the agricultural, organizational, and technological groundwork for the creation of classic Chacoan civilization, which lasted about 200 years--only to collapse spectacularly in a mere 40.Why did such a great society collapse? Who survived? Why? In this lively book anthropologist/archaeologist David Stuart presents answers to these questions that offer useful lessons to modern societies. His account of the rise and fall of the Chaco Anasazi brings to life the people known to us today as the architects of Chaco Canyon, the spectacular national park in New Mexico that thousands of tourists visit every year.

    Grant against Robert E. Lee for the first time in the Civil War-vividly re-creates the battles and maneuvers from the stalemate on the North Anna River through the Cold Harbor offensive. Cold Harbor: Grant and Lee, May 26-June 3, 1864 showcases Rhea's tenacious research which elicits stunning new facts from the records of a phase oddly ignored or mythologized by historians. In clear and profuse tactical detail, Rhea tracks the remarkable events of those nine days, giving a surprising new interpretation of the famous battle that left seven thousand Union casualties and only fifteen hundred Confederate dead or wounded. Here, Grant is not a callous butcher, and Lee does not wage a perfect fight. Within the pages of Cold Harbor, Rhea separates fact from fiction in a charged, evocative narrative. He leaves readers under a moonless sky, with Grant pondering the eastward course of the James River fifteen miles south of the encamped armies.

    The most exciting book on music in years. A book of treasure, a book of discovery, a book to open your ears to new worlds of pleasure. Doing for music what Patricia Schultz—author of the phenomenal 1,000 Places to See Before You Die—does for travel, Tom Moon recommends 1,000 recordings guaranteed to give listeners the joy, the mystery, the revelation, the sheer fun of great music. This is a book both broad and deep, drawing from the diverse worlds of classical, jazz, rock, pop, blues, country, folk, musicals, hip-hop, world, opera, soundtracks, and more. It's arranged alphabetically by artist to create the kind of unexpected juxtapositions that break down genre bias and broaden listeners’ horizons— it makes every listener a seeker, actively pursuing new artists and new sounds, and reconfirming the greatness of the classics. Flanking J. S. Bach and his six entries, for example, are the little-known R&B singer Baby Huey and the '80s Rastafarian hard-core punk band Bad Brains. Farther down the list: The Band, Samuel Barber, Cecelia Bartoli, Count Basie, and Afropop star Waldemer Bastos. Each entry is passionately written, with expert listening notes, fascinating anecdotes, and the occasional perfect quote—"Your collection could be filled with nothing but music from Ray Charles," said Tom Waits, "and you'd have a completely balanced diet." Every entry identifies key tracks, additional works by the artist, and where to go next. And in the back, indexes and playlists for different moods and occasions.

    His size and pace seemed to make him unstoppable - and he was still just 20, having only recently learned to play on the wing. How much better would he get? But a year later, a rare and serious kidney disorder threatened more than his career. He fought back, and continued to score tries at a remarkable rate.Lomu's astonishing story is not just about tries, but about adapting to becoming rugby's first superstar of the professional era, a life lived in the spotlight. This is an extraordinary tale from an extraordinary man.

    As a result of his famous "double pincer" maneuver, 70,000 Roman soldiers died within the space of a few hours on a field the size of New York's Central Park. Yet, as devastating and startling as Cannae was, it was only one of a long list of incredible achievements. Hannibal's fantastic 1,000-mile march across the Alps from Spain to Italy was one of the wonders of ancient times. He began his hazardous journey with 90,000 infantry, 12,000 cavalry, and 37 elephants. By the time he reached the Valley of the Po, more than 30,000 troops and many of his elephants had perished, but he still managed to stay in Italy for sixteen years.Blending biography and military adventure, Hannibal is a portrait of a military genius who was also a highly civilized man. The son of Hamilcar Barca, a famous general in his own right, Hannibal was a student of the Greek classics. But his father's lifelong grudge against Rome fostered in the son a deep hatred for that Republic and a fierce determination to subdue it forever. This resulted in the bloody battles of Lake Trasimene, Campania, Nole, Capua, and Zama, all of which Leonard Cottrell describes with vigor and authority. In gathering material for Hannibal, Cottrell traveled the entire route that Hannibal took across the Alps, thus bringing to his account a valuable firsthand knowledge of his subject. With the drama and authenticity for which he is famous, Leonard Cottrell describes Hannibal's amazing campaign-a saga of victory after victory which fell just short of its ultimate goal: the annihilation of Rome.

    Through the years historians have placed him at both ends of the spectrum: some have portrayed him as a hero, others have judged him incompetent.In Jefferson Davis and His Generals, Steven Woodworth shows that both extremes are accurate--Davis was both heroic and incompetent. Yet neither viewpoint reveals the whole truth about this complicated figure. Woodworth's portrait of Davis reveals an experienced, talented, and courageous leader who, nevertheless, undermined the Confederacy's cause in the trans-Appalachian west, where the South lost the war.At the war's outbreak, few Southerners seemed better qualified for the post of commander-in-chief. Davis had graduated from West Point, commanded a combat regiment in the Mexican War (which neither Lee nor Grant could boast), and performed admirably as U.S. Senator and Secretary of War. Despite his credentials, Woodworth argues, Davis proved too indecisive and inconsistent as commander-in-chief to lead his new nation to victory.As Woodworth shows, however, Davis does not bear the sole responsibility for the South's defeat. A substantial part of that burden rests with Davis's western generals. Bragg, Beauregard, Van Dorn, Pemberton, Polk, Buckner, Hood, Forrest, Morgan, and the Johnstons (Albert and Joseph) were a proud, contentious, and uneven lot. Few could be classed with the likes of a Lee or a Jackson in the east. Woodworth assesses their relations with Davis, as well as their leadership on and off the battlefields at Donelson, Shiloh, Vicksburg, Murfreesboro, Chickamauga, and Atlanta, to demonstrate their complicity in the Confederacy's demise.Extensive research in the marvelously rich holdings of the Jefferson Davis Association at Rice University enriches Woodworth's study. He provides superb analyses of western military operations, as well as some stranger-than-fiction tales: Van Dorn's shocking death, John Hood and Sally Preston's bizarre romance, Gideon Pillow's undignified antics, and Franklin Cheatham's drunken battlefield behavior. Most important, he has avoided the twin temptations to glorify or castigate Davis and thus restored balance to the evaluation of his leadership during the Civil War."A long-awaited work on an important topic--a counterpart for T. Harry Williams's celebrated Lincoln and His Generals. Experts in the field will have to take Woodworth into account. He writes well--in a good, clear style that should appeal to a wide audience. I found many passages to be pure pleasure to read. . . . The really exciting thing, though, is his insightful series of conclusions."--Herman Hattaway, author of How the North Won."Highly readable, stimulating, and at times even provocative. This fast-paced and compelling narrative provides a very effective overview of Confederate command problems in the West."--Albert Castel, author of General Sterling Price and the Civil War in the West.

    No, not since Treasure Island... Actually, not since Jonah and the Whale has there been a sea saga to rival The Pirates! In an Adventure with Scientists, featuring the greatest sea-faring hero of all time, the immortal Pirate Captain, who, although he lives for months at a time at sea, somehow manages to keep his beard silky and in good condition. Worried that his pirates are growing bored with a life of winking at pretty native ladies and trying to stick enough jellyfish together to make a bouncy castle, the Pirate Captain decides it's high time to spearhead an adventure. While searching for some major pirate booty, he mistakenly attacks the young Charles Darwin's Beagle and then leads his ragtag crew from the exotic Galapagos Islands to the fog-filled streets of Victorian London. There they encounter grisly murder, vanishing ladies, radioactive elephants, and the Holy Ghost himself. And that's not even the half of it.

    This is the thrilling untold story of the young helicopter pilots -- most barely out of their teens -- who risked their lives during this brief but ferocious war. In April 1982 Harry Benson was a 21 year-old Royal Navy commando helicopter pilot, fresh out of training and one of the youngest helicopter pilots to serve in the Falklands War. These pilots, nicknamed 'junglies', flew most of the land-based missions in the Falklands in their Sea King and Wessex helicopters. Much of what happened in the war -- the politics, task force ships, Sea Harriers, landings, Paras and Marines -- is well-known and documented. But almost nothing is known of the young commando helicopter pilots and aircrewmen who made it all happen on land and sea. This is their 'Boys Own' story, told for the very first time. Harry Benson has interviewed forty of his former colleagues for the book creating a tale of skill, initiative, resourcefulness, humour, luck, and adventure. This is a fast-paced, meticulously researched and compelling account written by someone who was there, in the cockpit of a Wessex helicopter.  None of these pilots has spoken before about: - The two helicopter crashes and eventual rescue following a failed SAS mission high up on an in hospitable glacier in South Georgia - The harrowing story of the Exocet strike that sunk the transport ship Atlantic Conveyor - The daring missile raid on the Argentine high command in Port Stanley - The constant mortar fire faced while supporting troops and evacuating casualties - The hair-raising head-on attacks by Argentine jets on British helicopters - The extraordinary courage shown during the evacuation of the bombed landing ship 'Sir Galahad'  If you liked Apache, Vulcan 607 and Chickenhawk, you'll love Scram!  The word "Scram" was coined by Falklands helicopter pilots to warn other 'junglies' to go to ground or risk being shot down as Argentinean jets blasted through 'bomb alley'. The term has never been used before or since.

    bombers began pounding Al Qaeda and Taliban forces. His dispatches provide an unprecedented and riveting on-the-ground account of the Afghan conflict, and his e-mails to the magazine — selections of which frame the pieces here — paint a vivid behind-the-scenes portrait of war journalism. From the battle for the Taliban bastion of Kunduz and the interim government's clumsy takeover of Kabul, to the search for Osama bin Laden in the Tora Bora caves and the truth of Al Qaeda's assassination of charismatic Northern Alliance leader Ahmad Shah Massoud — two days before September 11, 2001 — Anderson offers an unprecedented look into the forces that shape the conflict and the players who may threaten Afghanistan's future. In the distinguished tradition of New Yorker war reporting, The Lion's Grave illuminates a region to which we will be inextricably bound for some time to come.

    Mystic Seaport's bookstore has acquired a number of copies in excellent condition, and they are available from this catalog or from the bookstore as long as they last. This analysis of storms at sea and the behavior of yachts in them is both scientific and journalistic, including not only weather and wave-behavior data but accounts of storm experience and strategy from seasoned offshore sailors, not the least of them Adlard Coles himself. Typical storms in a number of locales are documented, and included is the 1979 Fastnet storm in four of the book's eleven appendixes.

    The new arms transformed society, too, as cities were built and rebuilt to limit the effects of bombardment by cannon. This book follows these far-reaching changes in comprehensive and fascinating detail and demonstrates how the innovations of the Renaissance paved the way to further changes in warfare.An in-depth technical look at the weaponry of the age and the tactical drills that honed the skills of Renaissance soldiersThe epic wars abroad between Western Christians and the Muslim Turks Civil strife at home between despotic rulers and rebellious forcesKingly duels that play out on an international stage

    He was the first to discover Australia and the Hawaiian Islands and the first to circumnavigate New Zealand. By the 1700s, England, eager to expand its realm of trade, promoted exploration of all the unclaimed regions of the world. The eighteenth century, the age of reason and enlightenment, required a new kind of explorer: not a rover or a plunderer or a seeker of adventure for its own sake, but a master of navigation and seamanship. Captain James Cook filled the bill. No one ever surpassed Cook's record. From South America to Australia, from the ice islands of the South Pacific to the fogbound Bering Strait, lay thousands of miles of islands, atolls, and ocean that Cook charted.

    It remains one of the largest losses of life ever in a maritime accident.At more than a hundred feet deep in the frigid Gulf of St. Lawrence, diving the "Empress" is like trying to navigate an unfamiliar sixty-story building lying on its side at a forty-five-degree angle, in pitch blackness with only a flashlight. In "Dark Descent," Kevin McMurray takes us deep into the bowels of the lost ship, first to relive her tragic death and then to join the divers who have probed the wreck's secrets. It's an adventure from which some divers don't return."Impressively researched. . . . For those who love the lure of the deep water and the mysteries of shipwrecks, this specialized history will be a pleasure."--"Publishers Weekly""Kevin has a remarkable knack of adding life and realism. A great job."--R. W. Hamilton, Chairman of the Board, Divers Alert Network

    Each of the tales implores us to continue our human legacy, reminding us of the virtuous nature that is inherently ours but is often hidden by life’s daily struggles.This book set in medieval times contains spiritual stories that can change lives, involving Indian kings, mystics, princes, and farmers. Stripping away the distractions of the present day, author Santhosh K. Komaraju provides a poignant look at what truly matters and encourages us to seek the essence of who we really are.