In 1875, tuberculosis was the deadliest disease in the world, accountable for a third of all deaths. A diagnosis of TB—often called consumption—was a death sentence. Then, in a triumph of medical science, a German doctor named Robert Koch deployed an unprecedented scientific rigor to discover the bacteria that caused TB. Koch soon embarked on a remedy—a remedy that would be his undoing.   When Koch announced his cure for consumption, Arthur Conan Doyle, then a small-town doctor in England and sometime writer, went to Berlin to cover the event. Touring the ward of reportedly cured patients, he was horrified. Koch’s "remedy" was either sloppy science or outright fraud.   But to a world desperate for relief, Koch’s remedy wasn’t so easily dismissed. As Europe’s consumptives descended upon Berlin, Koch urgently tried to prove his case. Conan Doyle, meanwhile, returned to England determined to abandon medicine in favor of writing. In particular, he turned to a character inspired by the very scientific methods that Koch had formulated: Sherlock Holmes.   Capturing the moment when mystery and magic began to yield to science, The Remedy chronicles the stunning story of how the germ theory of disease became a true fact, how two men of ambition were emboldened to reach for something more, and how scientific discoveries evolve into social truths.

    In The Horse, the journalist and equestrienne Wendy Williams brings that story brilliantly to life.Williams chronicles the 56-million-year journey of horses as she visits with horse experts around the world, revealing what our biological affinities and differences can tell us about the bond between horses and humans, and what our noble companion may think and feel. Indeed, recent scientific breakthroughs regarding the social and cognitive capacities of the horse and its ability to adapt to changing ecosystems indicate that this animal is a major evolutionary triumph.Williams charts the course that leads to our modern Equus-from the protohorse to the Dutch warmbloods, thoroughbreds, and miniature horses of the twenty-first century. She observes magnificent ancient cave art that signals a deep respect and admiration for horses well before they were domesticated, visits the mountains of Wyoming with an expert in equine behavior to understand the dynamics of free-roaming mustangs, witnesses the fluid gracefulness of the famous Lipizzaners of Vienna, contemplates what life is like for the sure-footed, mustachioed Garrano horses who thrive on the rugged terrain of Galicia, celebrates the Takhi horses of Mongolia, and more. She blends profound scientific insights with remarkable stories to create a unique biography of the horse as a sentient being with a fascinating past and a finely nuanced mind.The Horse is a revelatory account of the animal who has been at our side through the ages, carrying us into battle and traveling with us across the plains. Enriched by Wendy Williams's own experience with horses, The Horse is a masterful work of narrative nonfiction that pays tribute to this champion of the natural world.

    Herzog’s groundbreaking research on animal rights activists, cockfighters, professional dog-show handlers, veterinary students, and biomedical researchers. Blending anthropology, behavioral economics, evolutionary psychology, and philosophy, Herzog carefully crafts a seamless narrative enriched with real-life anecdotes, scientific research, and his own sense of moral ambivalence.Alternately poignant, challenging, and laugh-out-loud funny, this enlightening and provocative book will forever change the way we look at our relationships with other creatures and, ultimately, how we see ourselves.

    Gonzalez-Crussi, from the Introduction An international bestseller, translated into eighteen languages, Paul de Kruif’s classic account of the first scientists to see and learn about the microscopic world continues to fascinate new readers. This is a timeless dramatization of the scientists, bacteriologists, doctors, and medical technicians who discovered the microbes and invented the vaccines to counter them. De Kruif writes about how seemingly simple but really fundamental discovers of science—for instance, how a microbe was first viewed in a clear drop of rain water, and when, for the first time, Louis Pasteur discovered that a simple vaccine could save a man from the ravages of rabies by attacking the microbes that cause it.

    After 3.8 billion years humankind is about to start evolving by new rules...From leading geopolitical expert and technology futurist Jamie Metzl comes a groundbreaking exploration of the many ways genetic-engineering is shaking the core foundations of our lives -- sex, war, love, and death.At the dawn of the genetics revolution, our DNA is becoming as readable, writable, and hackable as our information technology. But as humanity starts retooling our own genetic code, the choices we make today will be the difference between realizing breathtaking advances in human well-being and descending into a dangerous and potentially deadly genetic arms race.Enter the laboratories where scientists are turning science fiction into reality. Look towards a future where our deepest beliefs, morals, religions, and politics are challenged like never before and the very essence of what it means to be human is at play. When we can engineer our future children, massively extend our lifespans, build life from scratch, and recreate the plant and animal world, should we?

    Unlike their human counterparts, who must alter their environment to accommodate our physical limitations, animals are adaptable to an amazing range of conditions--i.e., radical changes in a creature's physiology take place to match the demands of the environment. Winter provides an especially remarkable situation, because of how drastically it affects the most elemental component of all life: water.Examining everything from food sources in the extremely barren winter landscape to the chemical composition that allows certain creatures to survive, Heinrich's Winter World awakens the largely undiscovered mysteries by which nature sustains herself through the harsh, cruel exigencies of winters

    In this gripping, true account of the war against worldwide epidemics, one of medicine's frontline generals, Dr. Joseph McCormick, developer of the CDC's legendary hot zone, chronicles his decades as a virus hunter, working to combat the virus as predator. 16-pages of photos.

    In Elephants on Acid, Boese details the results of this scientific trial, as well as answers to the questions: Why can't people tickle themselves? Would the average dog summon help in an emergency? Will babies instinctually pick a well-balanced diet? Is it possible to restore life to the dead? Read on to find out...

    In Counting Backwards, pediatric anesthesiologist Dr. Henry Jay Przybylo delivers an unforgettable account of the procedure’s daily dramas and fundamental mysteries. Przybylo has administered anesthesia more than 30,000 times over his thirty-year career: on newborn babies, screaming toddlers, sullen teenagers, even a gorilla. Filled with intense moments of near-disaster, life-saving successes, and simple grace, Counting Backwards is for anyone curious about what happens after we lose consciousness.

    In the midst of all this death, a bizarre disease appeared in Europe. Eventually known as encephalitis lethargica, or sleeping sickness, it would spread across the world, leaving millions dead or locked in institutions. Then, in 1927, it would disappear as suddenly as it had arrived-or so the doctors at first thought. Asleep, set in 1920s and '30s New York, follows a group of neurologists through hospitals and insane asylums as they try to solve this worldwide epidemic. The symptoms could include not only unending sleep but dangerous insomnia, facial tics, catatonia, Parkinson's, and even violent insanity. Molly Caldwell Crosby, acclaimed author of The American Plague, explores the frightening history of this forgotten disease- and details the frantic effort to conquer it before it strikes again.

    This is a new view of mathematics, not the one we learned at school but a comprehensive guide to the patterns that recur through the universe and underlie human affairs. A Beginner's Guide to Constructing, the Universe shows you: Why cans, pizza, and manhole covers are round.Why one and two weren't considered numbers by the ancient Greeks.Why squares show up so often in goddess art and board games.What property makes the spiral the most widespread shape in nature, from embryos and hair curls to hurricanes and galaxies. How the human body shares the design of a bean plant and the solar system. How a snowflake is like Stonehenge, and a beehive like a calendar. How our ten fingers hold the secrets of both a lobster a cathedral, and much more.

    Learning all the tongue twisting names, picking favorites based on ferocity, armor, or sheer size. For many kids this love of ‘terrible lizards’ fizzles out at some point between starting and leaving primary school. All those fancy names slowly forgotten, no longer any need for a favorite.For all those child dino fanatics who didn’t grow up to become paleontologists, dinosaurs seem like something out of mythology. They are dragons, pictures in books, abstract, other, extinct.They are at the same time familiar and mysterious. And yet we’re in an age of rapid discovery—new dinosaur species and genera are being discovered at an accelerating rate, we’re learning more about what they looked like, how they lived, how they evolved and where they all went.This series isn’t just a top trumps list of dino facts—we’re interested in the why and the how and like all areas of science there is plenty of controversy and debate.

    But in the full history of life, ancient animals, even the trilobites, form only the half-billion-year tip of a nearly four-billion-year iceberg. Andrew Knoll explores the deep history of life from its origins on a young planet to the incredible Cambrian explosion, presenting a compelling new explanation for the emergence of biological novelty. The very latest discoveries in paleontology--many of them made by the author and his students--are integrated with emerging insights from molecular biology and earth system science to forge a broad understanding of how the biological diversity that surrounds us came to be. Moving from Siberia to Namibia to the Bahamas, Knoll shows how life and environment have evolved together through Earth's history. Innovations in biology have helped shape our air and oceans, and, just as surely, environmental change has influenced the course of evolution, repeatedly closing off opportunities for some species while opening avenues for others. Readers go into the field to confront fossils, enter the lab to discern the inner workings of cells, and alight on Mars to ask how our terrestrial experience can guide exploration for life beyond our planet. Along the way, Knoll brings us up-to-date on some of science's hottest questions, from the oldest fossils and claims of life beyond the Earth to the hypothesis of global glaciation and Knoll's own unifying concept of ''permissive ecology.'' In laying bare Earth's deepest biological roots, Life on a Young Planet helps us understand our own place in the universe--and our responsibility as stewards of a world four billion years in the making.In a new preface, Knoll describes how the field has broadened and deepened in the decade since the book's original publication.

    1 comes a fascinating chronicle of life’s history told not through the fossil record but through the stories of organisms that have survived, almost unchanged, throughout time. Evolution, it seems, has not completely obliterated its tracks as more advanced organisms have evolved; the history of life on earth is far older—and odder—than many of us realize.   Scattered across the globe, these remarkable plants and animals continue to mark seminal events in geological time. From a moonlit beach in Delaware, where the hardy horseshoe crab shuffles its way to a frenzy of mass mating just as it did 450 million years ago, to the dense rainforests of New Zealand, where the elusive, unprepossessing velvet worm has burrowed deep into rotting timber since before the breakup of the ancient supercontinent, to a stretch of Australian coastline with stromatolite formations that bear witness to the Precambrian dawn, the existence of these survivors offers us a tantalizing glimpse of pivotal points in evolutionary history. These are not “living fossils” but rather a handful of tenacious creatures of days long gone.   Written in buoyant, sparkling prose, Horseshoe Crabs and Velvet Worms is a marvelously captivating exploration of the world’s old-timers combining the very best of science writing with an explorer’s sense of adventure and wonder.

    In Under the Knife, surgeon Arnold Van de Laar uses his own experience and expertise to tell the witty history of the past, present and future of surgery.From the story of the desperate man from seventeenth-century Amsterdam who grimly cut a stone out of his own bladder to Bob Marley's deadly toe, Under the Knife offers all kinds of fascinating and unforgettable insights into medicine and history via the operating theatre.What happens during an operation? How does the human body respond to being attacked by a knife, a bacterium, a cancer cell or a bullet? And, as medical advances continuously push the boundaries of what medicine can cure, what are the limits of surgery?From the dark centuries of bloodletting and of amputations without anaesthetic to today's sterile, high-tech operating theatres, Under the Knife is both a rich cultural history, and a modern anatomy class for us all.