Includes genealogical tables, coats of arms, and royal heraldry.

    The most up-to-date and beautifully illustrated text on the market, it has a strong molecular and cellular approach, firmly relating the molecular and cellular biological underpinnings of physiology to the study of human physiology and disease. Contributions from leading physiologists ensure authoritative, cutting-edge information, and thorough and consistent editing have produced a readable and student-friendly text.The smart way to study!Elsevier titles with STUDENT CONSULT will help you master difficult concepts and study more efficiently in print and online! Perform rapid searches. Integrate bonus content from other disciplines. Download text to your handheld device. And a lot more. Each STUDENT CONSULT title comes with full text online, a unique image library, case studies, USMLE style questions, and online note-taking to enhance your learning experience.

    Born with the rare genetic condition progeria, she ages eight times faster than the average person. In medical terms her body is like that of a 100-year-old woman. Yet she faces her condition with immense courage and a refreshing lack of self-pity. In Old Before My Time, Hayley and her mum Kerry reflect on her unusual life. Share Hayley's excitement as she travels the world meeting her pop heroes Kylie, Girls Aloud and Justin Bieber and her sadness as she loses her best friend to the disease at the age of 11. Now as she passes the age of 13 -- the average life expectancy for a child with progeria -- Hayley talks frankly about her hopes for the future and her pioneering drug trials in America which could unlock the secrets of ageing for everyone...

    Judt masterfully crystallizes what we’ve all been feeling into a way to think our way into, and thus out of, our great collective dis-ease about the current state of things.As the economic collapse of 2008 made clear, the social contract that defined postwar life in Europe and America – the guarantee of a basal level of security, stability and fairness -- is no longer guaranteed; in fact, it’s no longer part of the common discourse. Judt offers the language we need to address our common needs, rejecting the nihilistic individualism of the far right and the debunked socialism of the past. To find a way forward, we must look to our not so distant past and to social democracy in action: to re-enshrining fairness over mere efficiency.Distinctly absent from our national dialogue, social democrats believe that the state can play an enhanced role in our lives without threatening our liberties. Instead of placing blind faith in the market—as we have to our detriment for the past thirty years—social democrats entrust their fellow citizens and the state itself.Ill Fares the Land challenges us to confront our societal ills and to shoulder responsibility for the world we live in. For hope remains. In reintroducing alternatives to the status quo, Judt reinvigorates our political conversation, providing the tools necessary to imagine a new form of governance, a new way of life.

    And as outbreaks of COVID-19, Ebola, MERS, and Zika have demonstrated, we are woefully underprepared to deal with the fallout. So what can -- and must -- we do in order to protect ourselves from mankind's deadliest enemy?Drawing on the latest medical science, case studies, policy research, and hard-earned epidemiological lessons, Deadliest Enemy explores the resources and programs we need to develop if we are to keep ourselves safe from infectious disease. The authors show how we could wake up to a reality in which many antibiotics no longer cure, bioterror is a certainty, and the threat of a disastrous influenza or coronavirus pandemic looms ever larger. Only by understanding the challenges we face can we prevent the unthinkable from becoming the inevitable.Deadliest Enemy is high scientific drama, a chronicle of medical mystery and discovery, a reality check, and a practical plan of action.

    The wedding of the sixth son of King George III to the daughter of the Earl of Dunmore would not only be concealed – it would also be illegal.Lady Augusta Murray had known Prince Augustus Frederick for only three months but they had already fallen deeply in love and were desperate to be married. However, the Royal Marriages Act forbade such a union without the King’s permission and going ahead with the ceremony would change Augusta’s life forever. From a beautiful socialite she became a social pariah; her children were declared illegitimate and her family was scorned.In FORBIDDEN WIFE Julia Abel Smith uses material from the Royal Archives and the Dunmore family papers to create a dramatic biography set in the reigns of Kings George III and IV against the background of the American and French Revolutions.

    Born in a New York tenement, humble in manner, Salk had all the makings of a twentieth-century icon--a knight in a white coat. In the wake ofhis achievement, he received a staggering number of awards and honors; for years his name ranked with Gandhi and Churchill on lists of the most revered people. And yet the one group whose adulation he craved--the scientific community--remained ominously silent. The worst tragedy that could havebefallen me was my success, Salk later said. I knew right away that I was through--cast out.In the first complete biography of Jonas Salk, Charlotte DeCroes Jacobs unravels Salk's story to reveal an unconventional scientist and a misunderstood and vulnerable man. Despite his incredible success in developing the polio vaccine, Salk was ostracized by his fellow scientists, who accused him offailing to give proper credit to other researchers and scorned his taste for media attention. Even before success catapulted him into the limelight, Salk was an inscrutable man disliked by many of his peers. Driven by an intense desire to aid mankind, he was initially oblivious and eventuallyresigned to the personal cost--as well as the costs suffered by his family and friends. And yet Salk remained, in the eyes of the public, an adored hero.Based on hundreds of personal interviews and unprecedented access to Salk's sealed archives, Jacobs' biography offers the most complete picture of this complicated figure. Salk's story has never been fully told; until now, his role in preventing polio has overshadowed his part in co-developing thefirst influenza vaccine, his effort to meld the sciences and humanities in the magnificent Salk Institute, and his pioneering work on AIDS. A vivid and intimate portrait, this will become the standard work on the remarkable life of Jonas Salk.

    But in this groundbreaking book, prize-winning historian Edith Sheffer exposes that Asperger was not only involved in the racial policies of Hitler’s Third Reich, he was complicit in the murder of children.As the Nazi regime slaughtered millions across Europe during World War Two, it sorted people according to race, religion, behavior, and physical condition for either treatment or elimination. Nazi psychiatrists targeted children with different kinds of minds—especially those thought to lack social skills—claiming the Reich had no place for them. Asperger and his colleagues endeavored to mold certain "autistic" children into productive citizens, while transferring others they deemed untreatable to Spiegelgrund, one of the Reich’s deadliest child-killing centers.In the first comprehensive history of the links between autism and Nazism, Sheffer uncovers how a diagnosis common today emerged from the atrocities of the Third Reich. With vivid storytelling and wide-ranging research, Asperger’s Children will move readers to rethink how societies assess, label, and treat those diagnosed with disabilities.

    David Schneider’s The Invention of Surgery is an in-depth biography of the practice that has leapt forward over the centuries from the dangerous guesswork of ancient Greek physicians through the world-changing “implant revolution” of the twentieth century.The Invention of Surgery explains this dramatic progress and highlights the personalities of the discipline's most dynamic historical figures. It links together the lives of the pioneering scientists who first understood what causes disease, how organs become infected or cancerous, and how surgery could powerfully intercede in people’s lives, and then shows how the rise of surgery intersected with many of the greatest medical breakthroughs of the last century, including the evolution of medical education, the transformation of the hospital from a place of dying to a habitation of healing, the development of antibiotics, and the rise of transistors and polymer science.And as Schneider argues, surgery has not finished transforming; new technologies are constantly reinventing both the practice of surgery and the nature of the objects we are permanently implanting in our bodies. Schneider considers these latest developments, asking “What’s next?” and analyzing how our conception of surgery has changed alongside our evolving ideas of medicine, technology, and our bodies.

    history. She earned her degree thirty-one years before women could vote and thirty-five years before Indians could become citizens in their own country.By age twenty-six, this fragile but indomitable Indian woman became the doctor to her tribe. Overnight, she acquired 1,244 patients scattered across 1,350 square miles of rolling countryside with few roads. Her patients often were desperately poor and desperately sick—tuberculosis, small pox, measles, influenza—families scattered miles apart, whose last hope was a young woman who spoke their language and knew their customs.This is the story of an Indian woman who effectively became the chief of an entrenched patriarchal tribe, the story of a woman who crashed through thick walls of ethnic, racial and gender prejudice, then spent the rest of her life using a unique bicultural identity to improve the lot of her people—physically, emotionally, politically, and spiritually. A Warrior of the People is the moving biography of Susan La Flesche’s inspirational life, and it will finally shine a light on her numerous accomplishments.The author will donate all royalties from this book to a college scholarship fund he has established for Native American high school graduates.

    Two years later, Clea Koff, a twenty-three-year-old forensic anthropologist, left the safe confines of a lab in Berkeley, California, to serve as one of sixteen scientists chosen by the United Nations to unearth the physical evidence of the Rwandan genocide. Over the next four years, Koff’s grueling investigations took her across geography synonymous with some of the worst crimes of the twentieth century. The Bone Woman is Koff’s unflinching, riveting account of her seven UN missions to Bosnia, Croatia, Kosovo, and Rwanda, as she shares what she saw, how it affected her, who was prosecuted based on evidence she found, and what she learned about the world. Yet even as she recounts the hellish nature of her work and the heartbreak of the survivors, she imbues her story with purpose, humanity, and a sense of justice. A tale of science in service of human rights, The Bone Woman is, even more profoundly, a story of hope and enduring moral principles.

    Rick Strassman conducted US DEA-approved clinical research at the University of New Mexico in which he injected 60 volunteers with DMT, one of the most powerful psychedelics known. His detailed account of those sessions is an inquiry into the nature of the human mind and the therapeutic potential of psychedelics. DMT, a plant-derived chemical that is also manufactured by the human brain, consistently produced near-death and mystical experiences. Many volunteers reported convincing encounters with intelligent nonhuman presences, especially "aliens." Nearly all felt that the sessions were among the most profound experiences of their lives.Strassman's research connects DMT with the pineal gland, considered by Hindus to be the site of the seventh chakra and by René Descartes to be the seat of the soul. DMT: The Spirit Molecule makes the case that DMT, naturally released by the pineal gland, facilitates the soul's movement in and out of the body and is an integral part of the birth and death experiences, as well as the highest states of meditation and even sexual transcendence. Strassman also believes that alien abduction experiences are brought on by accidental releases of DMT. If used wisely, DMT could trigger a period of remarkable progress in the scientific exploration of the most mystical regions of the human mind and soul.

    A tale of love, bribery, poison, treachery and retribution in Jacobean England.

    Before the Norman Conquest, Anglo-Saxons living in a wintry world wrote about the coldness of exile or the shelters they had to defend against enemies outside. The Middle Ages brought the warmth of spring; the new lyrics were sung in praise of blossoms and cuckoos. Descriptions of a rainy night are rare before 1700, but by the end of the eighteenth century the Romantics had adopted the squall as a fit subject for their most probing thoughts.The weather is vast and yet we experience it intimately, and Alexandra Harris builds her remarkable story from small evocative details. There is the drawing of a twelfth-century man in February, warming bare toes by the fire. There is the tiny glass left behind from the Frost Fair of 1684, and the Sunspan house in Angmering that embodies the bright ambitions of the 1930s. Harris catches the distinct voices of compelling individuals. “Bloody cold,” says Jonathan Swift in the “slobbery” January of 1713. Percy Shelley wants to become a cloud and John Ruskin wants to bottle one. Weatherland is a celebration of English air and a life story of those who have lived in it.

    Judy Mikovits is a modern-day Rosalind Franklin, a brilliant researcher shaking up the old boys’ club of science with her groundbreaking discoveries. And like many women who have trespassed into the world of men, she uncovered decades-old secrets that many would prefer to stay buried. From her doctoral thesis, which changed the treatment of HIV-AIDS, saving the lives of millions, including basketball great Magic Johnson, to her spectacular discovery of a new family of human retroviruses, and her latest research which points to a new golden age of health, Dr. Mikovits has always been on the leading edge of science. With the brilliant wit one might expect if Erin Brockovich had a doctorate in molecular biology, Dr. Mikovits has seen the best and worst of science. When she was part of the research community that turned HIV-AIDS from a fatal disease into a manageable one, she saw science at its best. But when her investigations questioned whether the use of animal tissue in medical research were unleashing devastating plagues of chronic diseases, such as autism and chronic fatigue syndrome, she saw science at its worst. If her suspicions are correct, we are looking at a complete realignment of scientific practices, including how we study and treat human disease. Recounting her nearly four decades in science, including her collaboration of more than thirty-five years with Dr. Frank Ruscetti, one of the founders of the field of human retrovirology, this is a behind the scenes look at the issues and egos which will determine the future health of humanity.