But by itself, DNA is just an inert blueprint for life. It is the ribosome--an enormous molecular machine made up of a million atoms--that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases. But this is also a human story of Ramakrishnan's unlikely journey, from his first fumbling experiments in a biology lab to being the dark horse in a fierce competition with some of the world's best scientists. In the end, Gene Machine is a frank insider's account of the pursuit of high-stakes science.

    Life remains the only way to make life. Are we still missing a vital ingredient in its creation?      Like Richard Dawkins' The Selfish Gene, which provided a new perspective on how evolution works, Life on the Edge alters our understanding of our world's fundamental dynamics. Bringing together first-hand experience at the cutting edge of science with unparalleled gifts of explanation, Jim Al-Khalili and Johnjoe Macfadden reveal that missing ingredient to be quantum mechanics; the phenomena that lie at the heart of this most mysterious of sciences. Drawing on recent ground-breaking experiments around the world, each chapter in Life on the Edge engages by illustrating one of life's puzzles: How do migrating birds know where to go? How do we really smell the scent of a rose? How do our genes copy themselves with such precision? Life on the Edge accessibly reveals how quantum mechanics can answer these probing questions of the universe. Guiding the reader through the rapidly unfolding discoveries of the last few years, Al-Khalili and McFadden communicate the excitement of the explosive new field of quantum biology and its potentially revolutionary applications, while offering insights into the biggest puzzle of all: what is life? As they brilliantly demonstrate in these groundbreaking pages, life exists on the quantum edge.

    In captivity, octopuses have been known to identify individual human keepers, raid neighboring tanks for food, turn off lightbulbs by spouting jets of water, plug drains, and make daring escapes. How is it that a creature with such gifts evolved through an evolutionary lineage so radically distant from our own? What does it mean that evolution built minds not once but at least twice? The octopus is the closest we will come to meeting an intelligent alien. What can we learn from the encounter?In Other Minds, Peter Godfrey-Smith, a distinguished philosopher of science and a skilled scuba diver, tells a bold new story of how subjective experience crept into being—how nature became aware of itself. As Godfrey-Smith stresses, it is a story that largely occurs in the ocean, where animals first appeared. Tracking the mind’s fitful development, Godfrey-Smith shows how unruly clumps of seaborne cells began living together and became capable of sensing, acting, and signaling. As these primitive organisms became more entangled with others, they grew more complicated. The first nervous systems evolved, probably in ancient relatives of jellyfish; later on, the cephalopods, which began as inconspicuous mollusks, abandoned their shells and rose above the ocean floor, searching for prey and acquiring the greater intelligence needed to do so. Taking an independent route, mammals and birds later began their own evolutionary journeys.But what kind of intelligence do cephalopods possess? Drawing on the latest scientific research and his own scuba-diving adventures, Godfrey-Smith probes the many mysteries that surround the lineage. How did the octopus, a solitary creature with little social life, become so smart? What is it like to have eight tentacles that are so packed with neurons that they virtually “think for themselves”? What happens when some octopuses abandon their hermit-like ways and congregate, as they do in a unique location off the coast of Australia?By tracing the question of inner life back to its roots and comparing human beings with our most remarkable animal relatives, Godfrey-Smith casts crucial new light on the octopus mind—and on our own.

    Wilczek’s groundbreaking work in quantum physics was inspired by his intuition to look for a deeper order of beauty in nature. In fact, every major advance in his career came from this intuition: to assume that the universe embodies beautiful forms, forms whose hallmarks are symmetry—harmony, balance, proportion—and economy. There are other meanings of “beauty,” but this is the deep logic of the universe—and it is no accident that it is also at the heart of what we find aesthetically pleasing and inspiring.Wilczek is hardly alone among great scientists in charting his course using beauty as his compass. As he reveals in A Beautiful Question, this has been the heart of scientific pursuit from Pythagoras, the ancient Greek who was the first to argue that “all things are number,” to Galileo, Newton, Maxwell, Einstein, and into the deep waters of twentiethcentury physics. Though the ancients weren’t right about everything, their ardent belief in the music of the spheres has proved true down to the quantum level. Indeed, Wilczek explores just how intertwined our ideas about beauty and art are with our scientific understanding of the cosmos.Wilczek brings us right to the edge of knowledge today, where the core insights of even the craziest quantum ideas apply principles we all understand. The equations for atoms and light are almost literally the same equations that govern musical instruments and sound; the subatomic particles that are responsible for most of our mass are determined by simple geometric symmetries. The universe itself, suggests Wilczek, seems to want to embody beautiful and elegant forms. Perhaps this force is the pure elegance of numbers, perhaps the work of a higher being, or somewhere between. Either way, we don’t depart from the infinite and infinitesimal after all; we’re profoundly connected to them, and we connect them. When we find that our sense of beauty is realized in the physical world, we are discovering something about the world, but also something about ourselves.Gorgeously illustrated, A Beautiful Question is a mind-shifting book that braids the age-old quest for beauty and the age-old quest for truth into a thrilling synthesis. It is a dazzling and important work from one of our best thinkers, whose humor and infectious sense of wonder animate every page. Yes: The world is a work of art, and its deepest truths are ones we already feel, as if they were somehow written in our souls.

    When Dr Ben Goldacre saw someone on daytime TV dipping her feet in an 'Aqua Detox' footbath, releasing her toxins into the water, turning it brown, he thought he'd try the same at home. 'Like some kind of Johnny Ball cum Witchfinder General', using his girlfriend's Barbie doll, he gently passed an electrical current through the warm salt water. It turned brown. In his words: 'before my very eyes, the world's first Detox Barbie was sat, with her feet in a pool of brown sludge, purged of a weekend's immorality.' Dr Ben Goldacre is the author of the Bad Science column in the Guardian. His book is about all the 'bad science' we are constantly bombarded with in the media and in advertising. At a time when science is used to prove everything and nothing, everyone has their own 'bad science' moments from the useless pie-chart on the back of cereal packets to the use of the word 'visibly' in cosmetics ads.

    But in the full history of life, ancient animals, even the trilobites, form only the half-billion-year tip of a nearly four-billion-year iceberg. Andrew Knoll explores the deep history of life from its origins on a young planet to the incredible Cambrian explosion, presenting a compelling new explanation for the emergence of biological novelty. The very latest discoveries in paleontology--many of them made by the author and his students--are integrated with emerging insights from molecular biology and earth system science to forge a broad understanding of how the biological diversity that surrounds us came to be. Moving from Siberia to Namibia to the Bahamas, Knoll shows how life and environment have evolved together through Earth's history. Innovations in biology have helped shape our air and oceans, and, just as surely, environmental change has influenced the course of evolution, repeatedly closing off opportunities for some species while opening avenues for others. Readers go into the field to confront fossils, enter the lab to discern the inner workings of cells, and alight on Mars to ask how our terrestrial experience can guide exploration for life beyond our planet. Along the way, Knoll brings us up-to-date on some of science's hottest questions, from the oldest fossils and claims of life beyond the Earth to the hypothesis of global glaciation and Knoll's own unifying concept of ''permissive ecology.'' In laying bare Earth's deepest biological roots, Life on a Young Planet helps us understand our own place in the universe--and our responsibility as stewards of a world four billion years in the making.In a new preface, Knoll describes how the field has broadened and deepened in the decade since the book's original publication.

    The term “complexity” can be misleading, however, because what makes West’s discoveries so beautiful is that he has found an underlying simplicity that unites the seemingly complex and diverse phenomena of living systems, including our bodies, our cities and our businesses. Fascinated by issues of aging and mortality, West applied the rigor of a physicist to the biological question of why we live as long as we do and no longer. The result was astonishing, and changed science, creating a new understanding of energy use and metabolism: West found that despite the riotous diversity in the sizes of mammals, they are all, to a large degree, scaled versions of each other. If you know the size of a mammal, you can use scaling laws to learn everything from how much food it eats per day, what its heart-rate is, how long it will take to mature, its lifespan, and so on. Furthermore, the efficiency of the mammal’s circulatory systems scales up precisely based on weight: if you compare a mouse, a human and an elephant on a logarithmic graph, you find with every doubling of average weight, a species gets 25% more efficient—and lives 25% longer. This speaks to everything from how long we can expect to live to how many hours of sleep we need. Fundamentally, he has proven, the issue has to do with the fractal geometry of the networks that supply energy and remove waste from the organism's body. West's work has been game-changing for biologists, but then he made the even bolder move of exploring his work's applicability to cities. Cities, too, are constellations of networks and laws of scalability relate with eerie precision to them. For every doubling in a city's size, the city needs 15% less road, electrical wire, and gas stations to support the same population. More amazingly, for every doubling in size, cities produce 15% more patents and more wealth, as well as 15% more crime and disease. This broad pattern lays the groundwork for a new science of cities. Recently, West has applied his revolutionary work on cities and biological life to the business world. This investigation has led to powerful insights into why some companies thrive while others fail. The implications of these discoveries are far-reaching, and are just beginning to be explored. Scale is a thrilling scientific adventure story about the elemental natural laws that bind us together in simple but profound ways. Through the brilliant mind of Geoffrey West, we can envision how cities, companies and biological life alike are dancing to the same simple, powerful tune, however diverse and unrelated they are to each other.From the Hardcover edition.

    New technologies have revealed secrets locked in prehistoric bones that no one could have previously predicted. We can now work out the color of dinosaurs, the force of their bite, their top speeds, and even how they cared for their young.Remarkable new fossil discoveries—giant sauropod dinosaur skeletons in Patagonia, dinosaurs with feathers in China, and a tiny dinosaur tail in Burmese amber—remain the lifeblood of modern paleobiology. Thanks to advances in technologies and methods, however, there has been a recent revolution in the scope of new information gleaned from such fossil finds.In Dinosaurs Rediscovered, leading paleontologist Michael J. Benton gathers together all the latest paleontological evidence, tracing the transformation of dinosaur study from its roots in antiquated natural history to an indisputably scientific field. Among other things, the book explores how dinosaur remains are found and excavated, and especially how paleontologists read the details of dinosaurs’ lives from their fossils—their colors, their growth, and even whether we will ever be able to bring them back to life. Benton’s account shows that, though extinct, dinosaurs are still very much a part of our world.

    Why do we recognize patterns? Is there such a thing as positive stress? Are we genetically programmed to be in conflict with each other? Those are just some of the 150 questions that the world's best scientific minds answer with elegant simplicity.With contributions from Jared Diamond, Richard Dawkins, Nassim Taleb, Brian Eno, Steven Pinker, and more, everything is explained in fun, uncomplicated terms that make the most complex concepts easy to comprehend.

    Here is the Naked Ape at his most primal in love, at work, at war. Meet man as he really is: relative to the apes, stripped of his veneer as we see him courting, making love, sleeping, socializing, grooming, playing. The Naked Ape takes its place alongside Darwin’s Origin of the Species, presenting man not as a fallen angel, but as a risen ape, remarkable in his resilience, energy and imagination, yet an animal nonetheless, in danger of forgetting his origins. With its penetrating insights on man's beginnings, sex life, habits and our astonishing bonds to the animal kingdom, The Naked Ape is a landmark, at once provocative, compelling and timeless.

    Having just completed his masterpiece, The General Theory of Relativity—which provided a brand-new theory of gravity and promised a new perspective on the cosmos as a whole—he set out at once to share his excitement with as wide a public as possible in this popular and accessible book.Here published for the first time as a Penguin Classic, this edition of Relativity features a new introduction by bestselling science author Nigel Calder.

    How they got here, persevered, and ultimately thrived is a story that resonates from the Pleistocene to our modern era. The lower sea levels of the Ice Age exposed a vast land bridge between Asia and North America, but the land bridge was not the only way across. Different people arrived from different directions, and not all at the same time.The first explorers of the New World were few, their encampments fleeting. The continent they reached had no people but was inhabited by megafauna--mastodons, giant bears, mammoths, saber-toothed cats, five-hundred-pound panthers, enormous bison, and sloths that stood one story tall. The first people were hunters--Paleolithic spear points are still encrusted with the proteins of their prey--but they were wildly outnumbered and many would themselves have been prey to the much larger animals.Atlas of a Lost World chronicles the last millennia of the Ice Age, the violent oscillations and retreat of glaciers, the clues and traces that document the first encounters of early humans, and the animals whose presence governed the humans' chances for survival. A blend of science and personal narrative reveals how much has changed since the time of mammoth hunters, and how little. Across unexplored landscapes yet to be peopled, readers will see the Ice Age, and their own age, in a whole new light.

    Just about everyone has at least heard of Albert Einstein's formulation of 1905, which came into the world as something of an afterthought. But far fewer can explain his insightful linkage of energy to mass. David Bodanis offers an easily grasped gloss on the equation. Mass, he writes, "is simply the ultimate type of condensed or concentrated energy," whereas energy "is what billows out as an alternate form of mass under the right circumstances." Just what those circumstances are occupies much of Bodanis's book, which pays homage to Einstein and, just as important, to predecessors such as Maxwell, Faraday, and Lavoisier, who are not as well known as Einstein today. Balancing writerly energy and scholarly weight, Bodanis offers a primer in modern physics and cosmology, explaining that the universe today is an expression of mass that will, in some vastly distant future, one day slide back to the energy side of the equation, replacing the "dominion of matter" with "a great stillness"--a vision that is at once lovely and profoundly frightening. Without sliding into easy psychobiography, Bodanis explores other circumstances as well; namely, Einstein's background and character, which combined with a sterling intelligence to afford him an idiosyncratic view of the way things work--a view that would change the world. --Gregory McNamee

    In 2013, the New York Times published an obituary for Yvonne Brill. It began: “She made a mean beef stroganoff, followed her husband from job to job, and took eight years off from work to raise three children.” It wasn’t until the second paragraph that readers discovered why the Times had devoted several hundred words to her life: Brill was a brilliant rocket scientist who invented a propulsion system to keep communications satellites in orbit, and had recently been awarded the National Medal of Technology and Innovation. Among the questions the obituary—and consequent outcry—prompted were, Who are the role models for today’s female scientists, and where can we find the stories that cast them in their true light?      Headstrong delivers a powerful, global, and engaging response. Covering Nobel Prize winners and major innovators, as well as lesser-known but hugely significant scientists who influence our every day, Rachel Swaby’s vibrant profiles span centuries of courageous thinkers and illustrate how each one’s ideas developed, from their first moment of scientific engagement through the research and discovery for which they’re best known. This fascinating tour reveals these 52 women at their best—while encouraging and inspiring a new generation of girls to put on their lab coats.

     It was an ancient puzzle that stymied history's greatest minds: How did the fossils of seashells find their way far inland, sometimes high up into the mountains? Fossils only made sense in a world old enough to form them, and in the seventeenth century, few people could imagine such a thing. Texts no less authoritative than the Old Testament laid out very clearly the timescale of Earth's past; in fact one Anglican archbishop went so far as to calculate the exact date of Creation...October 23, 4004, B.C. A revolution was in the making, however, and it was started by the brilliant and enigmatic Nicholas Steno, the man whom Stephen Jay Gould called "the founder of geology." Steno explored beyond the pages of the Bible, looking directly at the clues left in the layers of the Earth. With his groundbreaking answer to the fossil question, Steno would not only confound the religious and scientific thinking of his own time, he would set the stage for the modern science that came after him. He would open the door to the concept of "deep time," which imagined a world with a history of millions or billions of years. And at the very moment his expansive new ideas began to unravel the Bible's authoritative claim as to the age of the Earth, Steno would enter the priesthood and rise to become a bishop, ultimately becoming venerated as a saint and beatified by the Catholic Church in 1988. Combining a thrilling scientific investigation with world-altering history and the portrait of an extraordinary genius, "The Seashell on the Mountaintop" gives us new insight into the very old planet on which we live, revealing how we learned to read the story told to us by the Earth itself, written in rock and stone.