Humans have feared them for centuries, long considering them the assassins and pariahs of the natural world.Now, in Venomous, the biologist Christie Wilcox investigates and illuminates the animals of our nightmares, arguing that they hold the keys to a deeper understanding of evolution, adaptation, and immunity. She reveals just how venoms function and what they do to the human body. With Wilcox as our guide, we encounter a jellyfish with tentacles covered in stinging cells that can kill humans in minutes; a two-inch caterpillar with toxic bristles that trigger hemorrhaging; and a stunning blue-ringed octopus capable of inducing total paralysis. How do these animals go about their deadly work? How did they develop such intricate, potent toxins? Wilcox takes us around the world and down to the cellular level to find out.Throughout her journey, Wilcox meets the intrepid scientists who risk their lives studying these lethal beasts, as well as “self-immunizers” who deliberately expose themselves to snakebites. Along the way, she puts her own life on the line, narrowly avoiding being envenomated herself. Drawing on her own research, Wilcox explains how venom scientists are untangling the mechanisms of some of our most devastating diseases, and reports on pharmacologists who are already exploiting venoms to produce lifesaving drugs. We discover that venomous creatures are in fact keystone species that play crucial roles in their ecosystems and ours—and for this alone, they ought to be protected and appreciated.Thrilling and surprising at every turn, Venomous will change everything you thought you knew about the planet’s most dangerous animals.

    A brilliant, unconventional rebel vilified for her strikingly modern notions of education, family, work, and personal relationships, she nevertheless strongly influenced political philosophy in Europe and a newborn America. Now acclaimed biographer Lyndall Gordon mounts a spirited defense of this courageous woman whose reputation has suffered over the years by painting a full and vibrant portrait of an extraordinary historical figure who was generations ahead of her time.

    Endowed with English royal blood on her mother's side, she was betrothed in infancy to Arthur, Prince of Wales, eldest son of Henry VII of England, an alliance that greatly benefited both sides. Yet Arthur died weeks after their marriage in 1501, and Catherine found herself remarried to his younger brother, soon to become Henry VIII. The history of England-and indeed of Europe-was forever altered by their union.Drawing on his deep knowledge of both Spain and England, Giles Tremlett has produced the first full biography in more than four decades of the tenacious woman whose marriage to Henry VIII lasted twice as long (twenty-four years) as his five other marriages combined. Her refusal to divorce him put her at the center of one of history's greatest power struggles, one that has resonated down through the centuries- Henry's break away from the Catholic Church as, bereft of a son, he attempted to annul his marriage to Catherine and wed Anne Boleyn. Catherine's daughter, Mary, would controversially inherit Henry's throne; briefly and bloodily, she returned England to the Catholicism of her mother's native Spain, foreshadowing the Spanish Armada some three decades later.From Catherine's peripatetic childhood at the glittering court of Ferdinand and Isabella to the battlefield at Flodden, where she, in Henry's absence abroad, led the English forces to victory against Scotland to her determination to remain queen and her last years in almost monastic isolation, Giles Tremlett vividly re-creates the life of a giant figure in the sixteenth century. Catherine of Aragon will take its place among the best of Tudor biography.

    He performed the first Caesarean in Africa, was deported from St Helena and gave Florence Nightingale a dressing down in the Crimea. At home, he was surrounded by a menagerie of animals, including a cat, a goat, a parrot and half a dozen small terriers. Long ago, in Cork, Ireland, he had also been a mother.This is the amazing true story of Margaret Ann Bulkley, the young woman who broke the rules of Georgian society to become one of the most respected surgeons of the century. Her life became one long, audacious act of deception that saw her rise to positions no woman had ever reached before, but it also left her isolated, even costing her the chance to be with the man she loved.

    What she does, with clarity, beauty, and candor, is to document, often in their most extreme moments, the complex lives of others. It’s her work, but it’s much more than that: it’s her singular calling.Lynsey Addario was just finding her way as a young photographer when September 11 changed the world. One of the few photojournalists with experience in Afghanistan, she gets the call to return and cover the American invasion. She makes a decision she would often find herself making—not to stay home, not to lead a quiet or predictable life, but to set out across the world, face the chaos of crisis, and make a name for herself.Addario finds a way to travel with a purpose. She photographs the Afghan people before and after the Taliban reign, the civilian casualties and misunderstood insurgents of the Iraq War, as well as the burned villages and countless dead in Darfur. She exposes a culture of violence against women in the Congo and tells the riveting story of her headline-making kidnapping by pro-Qaddafi forces in the Libyan civil war.Addario takes bravery for granted but she is not fearless. She uses her fear and it creates empathy; it is that feeling, that empathy, that is essential to her work. We see this clearly on display as she interviews rape victims in the Congo, or photographs a fallen soldier with whom she had been embedded in Iraq, or documents the tragic lives of starving Somali children. Lynsey takes us there and we begin to understand how getting to the hard truth trumps fear.As a woman photojournalist determined to be taken as seriously as her male peers, Addario fights her way into a boys’ club of a profession. Rather than choose between her personal life and her career, Addario learns to strike a necessary balance. In the man who will become her husband, she finds at last a real love to complement her work, not take away from it, and as a new mother, she gains an all the more intensely personal understanding of the fragility of life.Watching uprisings unfold and people fight to the death for their freedom, Addario understands she is documenting not only news but also the fate of society. It’s What I Do is more than just a snapshot of life on the front lines; it is witness to the human cost of war.

    Judy Melinek began her training as a New York City forensic pathologist. With her husband T.J. and their toddler Daniel holding down the home front, Judy threw herself into the fascinating world of death investigation, performing autopsies, investigating death scenes, counseling grieving relatives. Working Stiff chronicles Judy's two years of training, taking readers behind the police tape of some of the most harrowing deaths in the Big Apple, including a firsthand account of the events of September 11, the subsequent anthrax bio-terrorism attack, and the disastrous crash of American Airlines flight 587.Lively, action-packed, and loaded with mordant wit, Working Stiff offers a firsthand account of daily life in one of America's most arduous professions, and the unexpected challenges of shuttling between the domains of the living and the dead. The body never lies, and through the murders, accidents, and suicides that land on her table, Dr. Melinek lays bare the truth behind the glamorized depictions of autopsy work on shows like CSI and Law and Order to reveal the secret story of the real morgue.

    In my case, blinking my left eyelid is my only means of communication.’In December 1995, Jean-Dominique Bauby, editor-in-chief of French ‘Elle’ and the father of two young children, suffered a massive stroke and found himself paralysed and speechless, but entirely conscious, trapped by what doctors call ‘locked-in syndrome’. Using his only functioning muscle – his left eyelid – he began dictating this remarkable story, painstakingly spelling it out letter by letter.His book offers a haunting, harrowing look inside the cruel prison of locked-in syndrome, but it is also a triumph of the human spirit.

    At the age of forty-eight, on the verge of a divorce, Rita left an elegant life in L.A. to follow her dream of connecting with people in cultures all over the world. In 1986 she sold her possessions and became a nomad, living in a Zapotec village in Mexico, sleeping with sea lions on the Galapagos Islands, and residing everywhere from thatched huts to regal palaces. She has observed orangutans in the rain forest of Borneo, visited trance healers and dens of black magic, and cooked with women on fires all over the world. Rita’s example encourages us all to dust off our dreams and rediscover the joy, the exuberance, and the hidden spirit that so many of us bury when we become adults.

    For most of that time, she didn't know why. All of her trips to the ER and her daily anguish, pain, and lethargy only ever resulted in one question: How could any one person be this sick? Several drug addictions, three major hospitalizations, and over $100,000 later, she finally had a diagnosis: late-stage Lyme disease. Sick is Khakpour's arduous, emotional journey—as a woman, a writer, and a lifelong sufferer of undiagnosed health problems—through the chronic illness that perpetually left her a victim of anxiety, living a life stymied by an unknown condition.Divided by settings, Khakpour guides the reader through her illness by way of the locations that changed her course—New York, LA, New Mexico, and Germany—as she meditates on both the physical and psychological impacts of uncertainty, and the eventual challenge of accepting the diagnosis she had searched for over the course of her adult life. With candor and grace, she examines her subsequent struggles with mental illness, her addiction to the benzodiazepines prescribed by her psychiatrists, and her ever-deteriorating physical health. A story about survival, pain, and transformation, Sick is a candid, illuminating narrative of hope and uncertainty, boldly examining the deep impact of illness on one woman's life.

    She was a poor Southern tobacco farmer who worked the same land as her enslaved ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine. The first “immortal” human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. If you could pile all HeLa cells ever grown onto a scale, they’d weigh more than 50 million metric tons—as much as a hundred Empire State Buildings. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions.Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave.Now Rebecca Skloot takes us on an extraordinary journey, from the “colored” ward of Johns Hopkins Hospital in the 1950s to stark white laboratories with freezers full of HeLa cells; from Henrietta’s small, dying hometown of Clover, Virginia — a land of wooden quarters for enslaved people, faith healings, and voodoo — to East Baltimore today, where her children and grandchildren live and struggle with the legacy of her cells.Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family — past and present — is inextricably connected to the history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of.Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah, who was devastated to learn about her mother’s cells. She was consumed with questions: Had scientists cloned her mother? Did it hurt her when researchers infected her cells with viruses and shot them into space? What happened to her sister, Elsie, who died in a mental institution at the age of fifteen? And if her mother was so important to medicine, why couldn’t her children afford health insurance?Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.

    When Carrie Fisher discovered the journals she kept during the filming of the first Star Wars movie, she was astonished to see what they had preserved--plaintive love poems, unbridled musings with youthful naiveté, and a vulnerability that she barely recognized. Before her passing, her fame as an author, actress, and pop-culture icon was indisputable, but in 1977, Carrie Fisher was just a teenager with an all-consuming crush on her costar, Harrison Ford.With these excerpts from her handwritten notebooks, The Princess Diarist is Fisher's intimate and revealing recollection of what happened on one of the most famous film sets of all time--and what developed behind the scenes. Fisher also ponders the joys and insanity of celebrity, and the absurdity of a life spawned by Hollywood royalty, only to be surpassed by her own outer-space royalty. Laugh-out-loud hilarious and endlessly quotable, The Princess Diarist brims with the candor and introspection of a diary while offering shrewd insight into one of Hollywood's most beloved stars.

    Doctors loathed this time-consuming procedure and for centuries relied on midwives. Later, they substituted the efficiency of mechanical devices, including the electric vibrator, invented in the 1880s. In The Technology of Orgasm, Rachel Maines offers readers a stimulating, surprising, and often humorous account of hysteria and its treatment throughout the ages, focusing on the development, use, and fall into disrepute of the vibrator as a legitimate medical device.

    Conley, the first female tenured professor of neurosurgery in the country, made headline news when she resigned from Stanford University to protest the medical school's unabashed gender discrimination. In this controversial, forthright memoir, Conley portrays the world of academic medicine in which women are still considered inferior; she also explains why, as a consequence, the research and treatment of women's health problems lag far behind those of men. In assessing why women's careers and psyches are suffering, Conley provides a first-person look into what it is like to be an accomplished woman within this restrictive medical world, offering invaluable advice to patients and future doctors alike.

    For Fauziya Kassindja, an idyllic childhood in Togo, West Africa, sheltered from the tribal practices of polygamy and genital mutilation, ended with her beloved father's sudden death.  Forced into an arranged marriage at age seventeen, Fauziya was told to prepare for kakia, the ritual also known as female genital mutilation.  It is a ritual no woman can refuse.  But Fauziya dared to try.  This is her story--told in her own words--of fleeing Africa just hours before the ritual kakia was to take place, of seeking asylum in America only to be locked up in U.S.  prisons, and of meeting Layli Miller Bashir, a law student who became Fauziya's friend and advocate during her horrifying sixteen months behind bars.  Layli enlisted help from Karen Musalo, an expert in refugee law and acting director of the American University International Human Rights Clinic.  In addition to devoting her own considerable efforts to the case, Musalo assembled a team to fight with her on Fauziya's behalf.  Ultimately, in a landmark decision in immigration history, Fauziya Kassindja was granted asylum on June 13, 1996.  Do They Hear You When You Cry is her unforgettable chronicle of triumph.

    Sidibe tells the engrossing, inspiring story of her first job as a phone sex “talker.” And she shares her unconventional (of course!) rise to fame as a movie star, alongside “a superstar cast of rich people who lived in mansions and had their own private islands and amazing careers while I lived in my mom's apartment.” Sidibe’s memoir hits hard with self-knowing dispatches on friendship, depression, celebrity, haters, fashion, race, and weight (“If I could just get the world to see me the way I see myself,” she writes, “would my body still be a thing you walked away thinking about?”). Irreverent, hilarious, and nontraditional, This Is Just My Face takes its place and fills a void on the shelf of writers from Mindy Kaling to David Sedaris to Lena Dunham.