As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his co-discovery of the structure of DNA. She and her collaborators turned ​a curiosity ​of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020.

    As a volunteer at a local orphanage, Bratt witnessed conditions that were unfathomable to a middle-class mother of two from South Carolina.Based on Bratt's diary of her four years at the orphanage, Silent Tears offers a searing account of young lives rendered disposable. In the face of an implacable system, Bratt found ways to work within (and around) the rules to make a better future for the children, whom she came to love. The book offers no easy answers. While often painful in its clear-sightedness, Silent Tears balances the sadness and struggles of life in the orphanage with moments of joy, optimism, faith, and victory. It is the story of hundreds of children and of one woman who never planned on becoming a hero but became one anyway.

    They reached Arlington’s highest point, where they encircled an old cream-colored mansion with thick columns and a commanding view of the cemetery, the river, and the city beyond. The mansion’s flag, just lowered to half-staff, signaled that it was time to start another day of funerals, which would add more than twenty new conscripts to Arlington’s army of the dead.” So does Robert Poole describe a day like so many others in the long and storied history of Arlington National Cemetery. Created towards the end of our greatest national crucible, the Civil War, its story—as revealed in On Hallowed Ground—reflects much of America’s own over the past century and a half. The mansion at its heart, and the rolling land on which it sits, had been the family plantation of Robert E. Lee before he joined the Confederacy; strategic to the defense of Washington, it became a Union headquarters, a haven for freedmen, and a burial ground for indigent soldiers before Secretary of War Edwin Stanton made it the latest in the newly established national cemetery system. It would become our nation’s most honored resting place. No other country makes the effort the United States does to recover and pay tribute to its war dead—an effort Poole reveals in poignant details from the aftermaths of the Civil War, Spanish-American War, World Wars I and II, Korea, Vietnam, and the conflicts in the Gulf and Afghanistan today. Every tombstone at Arlington tells a story: from Private William Christman, the first soldier buried at Arlington on May 13, 1864, to Union General Montgomery Meigs, whose idea Arlington was; from Lieutenant Thomas Selfridge, the first casualty of powered flight, to Audie Murphy, America’s most decorated soldier; from the Tomb of the Unknown Soldier, so lovingly tended today, to John F. Kennedy’s eternal flame; from scientists and slaves to jurists and generals and tens of thousands of ordinary citizen-warriors, among the more than 300,000 interred on Arlington’s 624 acres. Their sagas, and the rites and rituals that have evolved at Arlington—the horse-drawn caissons, marble headstones, playing of taps, and rifle salutes—speak to us all.

    She trained as a nurse and midwife, joined the Save the Children Fund, and was posted to Vietnam in 1967. Here, Anne was faced with a vision of hell that her training at Manchester's Royal Infirmary could not have prepared her for.

    His inventions, patents, and theoretical work formed the basis of modern AC electricity, and contributed to the development of radio and television. Like his competitor Thomas Edison, Tesla was one of America's first celebrity scientists, enjoying the company of New York high society and dazzling the likes of Mark Twain with his electrical demonstrations. An astute self-promoter and gifted showman, he cultivated a public image of the eccentric genius. Even at the end of his life when he was living in poverty, Tesla still attracted reporters to his annual birthday interview, regaling them with claims that he had invented a particle-beam weapon capable of bringing down enemy aircraft.Plenty of biographies glamorize Tesla and his eccentricities, but until now none has carefully examined what, how, and why he invented. In this groundbreaking book, W. Bernard Carlson demystifies the legendary inventor, placing him within the cultural and technological context of his time, and focusing on his inventions themselves as well as the creation and maintenance of his celebrity. Drawing on original documents from Tesla's private and public life, Carlson shows how he was an idealist inventor who sought the perfect experimental realization of a great idea or principle, and who skillfully sold his inventions to the public through mythmaking and illusion.This major biography sheds new light on Tesla's visionary approach to invention and the business strategies behind his most important technological breakthroughs.

    While paintings of Picasso and Jackson Pollock sell for a hundred million dollars or more, and lines from T. S. Eliot are quoted on the yearbook pages of alienated teenagers across the land, twentieth-century classical music still sends ripples of unease through audiences. At the same time, its influence can be felt everywhere. Atonal chords crop up in jazz. Avant-garde sounds populate the soundtracks of Hollywood thrillers. Minimalism has had a huge effect on rock, pop, and dance music from the Velvet Underground onward.The Rest Is Noise shows why twentieth-century composers felt compelled to create a famously bewildering variety of sounds, from the purest beauty to the purest noise. It tells of a remarkable array of maverick personalities who resisted the cult of the classical past, struggled against the indifference of a wide public, and defied the will of dictators. Whether they have charmed audiences with sweet sounds or battered them with dissonance, composers have always been exuberantly of the present, defying the stereotype of classical music as a dying art. The narrative goes from Vienna before the First World War to Paris in the twenties, from Hitler's Germany and Stalin's Russia to downtown New York in the sixties and seventies. We follow the rise of mass culture and mass politics, of dramatic new technologies, of hot and cold wars, of experiments, revolutions, riots, and friendships forged and broken. The end result is not so much a history of twentieth-century music as a history of the twentieth century through its music.

    Like when doctors prescribed morphine for crying infants. When snorting skull moss was a cure for a bloody nose. When consuming mail-order tapeworms was a latter-day fad diet. Or when snake oil salesmen peddled strychnine (used in rat poison) as an aphrodisiac in the '60s. Seamlessly combining macabre humor with hard science and compelling storytelling, Quackery is a visually rich and information-packed exploration of history's most outlandish cures, experiments, and scams.A humorous book that delves into some of the wacky but true ways that humans have looked to cure their ills. Leeches, mercury, strychnine, and lobotomies are a few of the topics that explore the lengths society has gone in the search for health.

    Accepting the increasingly widespread belief that industrialized culture inevitably erodes the natural world, Endgame sets out to explore how this relationship impels us towards a revolutionary and as-yet undiscovered shift in strategy. Building on a series of simple but increasingly provocative premises, Jensen leaves us hoping for what may be inevitable: a return to agrarian communal life via the disintegration of civilization itself.

    The Lockheed SR-71 Blackbird spy plane flew more than three-and-a-half times the speed of sound--so fast that no other aircraft could catch it. Above 80,000 feet, its pilots had to wear full-pressure flight suits similar to what was used aboard the space shuttle.Developed by the renowned Lockheed Skunk Works, the SR-71 was an awesome aircraft in every respect. It was withdrawn from use in 1998, when it was superseded by satellite technology. Twelve of the thirty-two aircraft were destroyed in accidents, but none were ever lost to enemy action.Throughout its thirty-four-year career, the SR-71 was the world's fastest and highest-flying operational manned aircraft. It set world records for altitude and speed: an absolute altitude record of 85,069 feet and an absolute speed record of 2,193.2 miles per hour.The Complete Book of the SR-71 Blackbird covers every aspect of the SR-71's development, manufacture, modification, and active service from the insider's perspective of one of its pilots and is lavishly illustrated with more than 400 photos. Former pilot and author Richard Graham also examines each of the fifty planes that came out the SR-71 program (fifteen A-12s; three YF-12s; and thirty-two SR-71s) and tells each plane's history, its unique specifications, and where each currently resides.

    The DOs chronicles the development of this controversial medical movement from the nineteenth century to the present. Historian Norman Gevitz describes the philosophy and practice of osteopathy, as well as its impact on medical care. From the theories underlying the use of spinal manipulation developed by osteopathy's founder, Andrew Taylor Still, Gevitz traces the movement's early success, despite attacks from the orthodox medical community, and details the internal struggles to broaden osteopathy's scope to include the full range of pharmaceuticals and surgery. He also recounts the efforts of osteopathic colleges to achieve parity with institutions granting M.D. degrees and looks at the continuing effort by osteopathic physicians and surgeons to achieve greater recognition and visibility.In print continuously since 1982, The DOs has now been thoroughly updated and expanded to include two new chapters addressing recent and current challenges and to bring the history of the profession up to the beginning of the new millennium.

    The Darkest Places chronicles mysterious disappearances, unsolved murders, and deadly disasters, taking us to far-flung places no sane person would want to go.

    The tent had been waterproofed with a mixture of paraffin and gasoline; in seconds it was burning out of control, and more than 8,000 people were trapped inside. Drawing on interviews with hundreds of survivors, O'Nan skillfully re-creates the horrific events and illuminates the psychological oddities of human behavior under stress: the mad scramble for the exits; the hero who tossed dozens of children to safety before being trampled to death. Brilliantly constructed and exceptionally moving, The Circus Fire is history at its most compelling.

    Seven months later, after joining a party of emigrants led by George Donner, they reached the Sierra Nevada Mountains as the first heavy snows of the season closed the pass ahead of them. In early December, starving and desperate, Sarah and fourteen others set out for California on snowshoes and, over the next thirty-two days, endured almost unfathomable hardships and horrors. In this gripping narrative, Daniel James Brown sheds new light on one of the most infamous events in American history. Following every painful footstep of Sarah's journey with the Donner Party, Brown produces a tale both spellbinding and richly informative.

    It accommodates four of our five senses, encases the brain, and boasts the most expressive set of muscles in the body. It is our most distinctive attribute and connects our inner selves to the outer world. Yet there is a dark side to the head’s preeminence, one that has, in the course of human history, manifested itself in everything from decapitation to headhunting. So explains anthropologist Frances Larson in this fascinating history of decapitated human heads. From the Western collectors whose demand for shrunken heads spurred massacres to Second World War soldiers who sent the remains of the Japanese home to their girlfriends, from Madame Tussaud modeling the guillotined head of Robespierre to Damien Hirst photographing decapitated heads in city morgues,from grave-robbing phrenologists to skull-obsessed scientists, Larson explores our macabre fixation with severed heads.

    Across the globe, we sat riveted to television and computer screens as journalists flocked to the Atacama desert. While we saw what transpired above ground during the grueling and protracted rescue, the story of the miners experiences below the earths surface and the lives that led them there hasn't been heard until now. In this master work of a Pulitzer Prizewinning journalist, Hctor Tobar gains exclusive access to the miners and their stories. The result is a miraculous and emotionally textured account of the thirty-three men who came to think of the San José mine as a kind of coffin, as a cave inflicting constant and thundering aural torment, and as a church where they sought redemption through prayer while the world watched from above. It offers an understanding of the families and personal histories that brought los 33 to the mine, and the mystical and spiritual elements that surrounded working in such a dangerous place.