This narrative, told through the stories and voices of the people caught in the deadly maelstrom, explores how this vast, global epidemic was intertwined with the horrors of World War I—and how it could happen again. Complete with photographs, period documents, modern research, and firsthand reports by medical professionals and survivors.

    How many of us understand the way seizures affect the brain, how the heart is connected to wellbeing, or the why the foot carries the key to our humanity? In Adventures in Human Being, award-winning author Gavin Francis leads readers on a journey into the hidden pathways of the human body, offering a guide to its inner workings and a celebration of its marvels.Drawing on his experiences as a surgeon, ER specialist, and family physician, Francis blends stories from the clinic with episodes from medical history, philosophy, and literature to describe the body in sickness and in health, in living and in dying. At its heart, Adventures in Human Being is a meditation on what it means to be human. Poetic, eloquent, and profoundly perceptive, this book will transform the way you view your body.

    Like when doctors prescribed morphine for crying infants. When snorting skull moss was a cure for a bloody nose. When consuming mail-order tapeworms was a latter-day fad diet. Or when snake oil salesmen peddled strychnine (used in rat poison) as an aphrodisiac in the '60s. Seamlessly combining macabre humor with hard science and compelling storytelling, Quackery is a visually rich and information-packed exploration of history's most outlandish cures, experiments, and scams.A humorous book that delves into some of the wacky but true ways that humans have looked to cure their ills. Leeches, mercury, strychnine, and lobotomies are a few of the topics that explore the lengths society has gone in the search for health.

    It is the history of who you are and how you came to be. It is unique to you, as it is to each of the 100 billion modern humans who have ever drawn breath. But it is also our collective story, because in every one of our genomes we each carry the history of our species births, deaths, disease, war, famine, migration, and a lot of sex. Since scientists first read the human genome in 2001, it has been subject to all sorts of claims, counterclaims, and myths. In fact, as Adam Rutherford explains, our genomes should be read not as instruction manuals, but as epic poems. DNA determines far less than we have been led to believe about us as individuals, but vastly more about us as a species. In this captivating journey through the expanding landscape of genetics, Adam Rutherford reveals what our genes now tell us about history, and what history tells us about our genes. From Neanderthals to murder, from redheads to race, dead kings to plague, evolution to epigenetics, this is a demystifying and illuminating new portrait of who we are and how we came to be."

    In Papua New Guinea, a primitive tribe is nearly obliterated by a sickness whose chief symptom is uncontrollable laughter. Across Europe, millions of sheep rub their fleeces raw before collapsing. In England, cows attack their owners in the milking parlors, while in the American West, thousands of deer starve to death in fields full of grass.What these strange conditions–including fatal familial insomnia, kuru, scrapie, and mad cow disease–share is their cause: prions. Prions are ordinary proteins that sometimes go wrong, resulting in neurological illnesses that are always fatal. Even more mysterious and frightening, prions are almost impossible to destroy because they are not alive and have no DNA–and the diseases they bring are now spreading around the world.In The Family That Couldn’t Sleep, essayist and journalist D. T. Max tells the spellbinding story of the prion’s hidden past and deadly future

    Striking humanity in waves, the cycle of plagues set the tempo of civilizational growth and decline, since common response to the threat was exclusion—quarantining the sick or keeping them out. But the unprecedented hygiene and medical revolutions of the past two centuries have allowed humanity to free itself from the hold of epidemic cycles—resulting in an urbanized, globalized, and unimaginably wealthy world. However, our development has lately become precarious. Climate and population fluctuations and aspects of our prosperity such as global trade have left us more vulnerable than ever to newly emerging plagues. Greater global cooperation toward sustainable health is urgently required—such as the international efforts to harvest a Covid-19 vaccine—with millions of lives and trillions of dollars at stake. Written as colorful history, The Plague Cycle reveals the relationship between civilization, globalization, prosperity, and infectious disease over the past five millennia. It harnesses history, economics, and public health, and charts humanity’s remarkable progress, providing a fascinating and timely look at the cyclical nature of infectious disease.

    When first published in 1969, this study was described by the Guardian as …as exciting and readable an account as you could wish." This new edition of the major study on the subject is illustrated by over seventy contemporary black and white illustrations and eight pages of color.A series of natural disasters in the furthest reaches of the Orient during the third of the fourteenth century heralded what was, for the population of Europe, the most devastating period of death and destruction in its history. By the autumn of 1347 the Black Death had reached the shores of the eastern Mediterranean, and the years that followed were to witness a horrifying and apparently relentless epidemic.One third of England's population died between the years 1347 and 1350, and over one thousand villages were deserted, never to be repopulated. In towns and cities the cemeteries were unable to provide space for all the dead, and violence and crime spiraled. Travel became dangerous and interruption of food and other supplies across the country added hunger and deprivation to the problems of people already overwhelmed by the threat of the vilest of deaths. In the countryside the population was halved in places, and as land became plentiful, landowners' profits fell and the government tried in vain to fix labourers' wages and prices, peasant unrest accelerated and the manorial system disintegrated, culminating eventually in the Peasants' Revolt of 1381. Throughout Europe whole societies were disrupted; racial tensions built as a direct result of the plague, and persecution of Jews began in earnest throughout the continent. The social and economic consequences of the period were to reach far into the following century.

    America faced a troubling question: What happened? How was this epidemic allowed to spread so far before it was taken seriously? In answering these questions, Shilts weaves the disparate threads into a coherent story, pinning down every evasion and contradiction at the highest levels of the medical, political, and media establishments. Shilts shows that the epidemic spread wildly because the federal government put budget ahead of the nation's welfare; health authorities placed political expediency before the public health; and scientists were often more concerned with international prestige than saving lives. Against this backdrop, Shilts tells the heroic stories of individuals in science and politics, public health and the gay community, who struggled to alert the nation to the enormity of the danger it faced. And the Band Played On is both a tribute to these heroic people and a stinging indictment of the institutions that failed the nation so badly.

    Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with - and perished from - for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. From the Persian Queen Atossa, whose Greek slave cut off her malignant breast, to the nineteenth-century recipients of primitive radiation and chemotherapy to Mukherjee’s own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through fiercely demanding regimens in order to survive—and to increase our understanding of this iconic disease. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

    In The Viral Storm, award-winning biologist Nathan Wolfe tells the story of how viruses and human beings have evolved side by side through history; how deadly viruses like HIV, swine flu, and bird flu almost wiped us out in the past; and why modern life has made our species vulnerable to the threat of a global pandemic.Wolfe's research missions to the jungles of Africa and the rain forests of Borneo have earned him the nickname "the Indiana Jones of virus hunters," and here Wolfe takes readers along on his groundbreaking and often dangerous research trips—to reveal the surprising origins of the most deadly diseases and to explain the role that viruses have played in human evolution.In a world where each new outbreak seems worse than the one before, Wolfe points the way forward, as new technologies are brought to bear in the most remote areas of the world to neutralize these viruses and even harness their power for the good of humanity. His provocative vision of the future will change the way we think about viruses, and perhaps remove a potential threat to humanity's survival.

    The media seized hold of the story and, in the process, helped to launch one of the most devastating health scares ever. In the years to come Wakefield would be revealed as a profiteer in league with class-action lawyers, and he would eventually lose his medical license. Meanwhile, one study after another failed to find any link between childhood vaccines and autism. Yet the myth that vaccines somehow cause developmental disorders lives on. Despite the lack of corroborating evidence, it has been popularized by media personalities such as Oprah Winfrey and Jenny McCarthy and legitimized by journalists who claim that they are just being fair to “both sides” of an issue about which there is little debate. Meanwhile, millions of dollars have been diverted from potential breakthroughs in autism research; families have spent their savings on ineffective “miracle cures"; and declining vaccination rates have led to outbreaks of deadly illnesses like Hib, measles, and whooping cough. Most tragic of all is the increasing number of children dying from vaccine-preventable diseases. In The Panic Virus Seth Mnookin draws on interviews with parents, public-health advocates, scientists, and anti-vaccine activists to tackle a fundamental question: How do we decide what the truth is? The fascinating answer helps explain everything from the persistence of conspiracy theories about 9/11 to the appeal of talk-show hosts who demand that President Obama “prove” he was born in America. The Panic Virus is the ultimate cautionary tale for our time.

    It infected nearly one-third of the world’s population and killed ten percent of those it struck. In its wake, schools and businesses closed, hospitals became overwhelmed, and the sick spilled out into makeshift care centers in public spaces. Policemen, public transportation workers, and everyday citizens in face masks were a common—and eerie—sight. Yet, discussion of this global pandemic often takes a backseat to World War I and other contemporary events.

    Phineas, a railroad construction foreman, was blasting rock near Cavendish, Vermont, in 1848 when a thirteen-pound iron rod was shot through his brain. Miraculously, he survived to live another eleven years and become a textbook case in brain science.At the time, Phineas Gage seemed to completely recover from his accident. He could walk, talk, work, and travel, but he was changed. Gage "was no longer Gage," said his Vermont doctor, meaning that the old Phineas was dependable and well liked, and the new Phineas was crude and unpredictable.His case astonished doctors in his day and still fascinates doctors today. What happened and what didn’t happen inside the brain of Phineas Gage will tell you a lot about how your brain works and how you act human.

    After barely surviving the agony of smallpox themselves, they flouted eighteenth-century medicine by borrowing folk knowledge from African slaves and Eastern women in frantic bids to protect their children. From their heroic struggles stems the modern science of immunology as well as the vaccinations that remain our only hope should the disease ever be unleashed again.Jennifer Lee Carrell transports readers back to the early eighteenth century to tell the tales of Lady Mary Wortley Montagu and Dr. Zabdiel Boylston, two iconoclastic figures who helped save London and Boston from the deadliest disease mankind has known.

    But sometimes, when obsession gets the better of scientists, they twist a noble pursuit into something sinister. Under this spell, knowledge isn’t everything, it’s the only thing—no matter the cost. Bestselling author Sam Kean tells the true story of what happens when unfettered ambition pushes otherwise rational men and women to cross the line in the name of science, trampling ethical boundaries and often committing crimes in the process.The Icepick Surgeon masterfully guides the reader across two thousand years of history, beginning with Cleopatra’s dark deeds in ancient Egypt. The book reveals the origins of much of modern science in the transatlantic slave trade of the 1700s, as well as Thomas Edison’s mercenary support of the electric chair and the warped logic of the spies who infiltrated the Manhattan Project. But the sins of science aren’t all safely buried in the past. Many of them, Kean reminds us, still affect us today. We can draw direct lines from the medical abuses of Tuskegee and Nazi Germany to current vaccine hesitancy, and connect icepick lobotomies from the 1950s to the contemporary failings of mental-health care. Kean even takes us into the future, when advanced computers and genetic engineering could unleash whole new ways to do one another wrong.Unflinching, and exhilarating to the last page, The Icepick Surgeon fuses the drama of scientific discovery with the illicit thrill of a true-crime tale. With his trademark wit and precision, Kean shows that, while science has done more good than harm in the world, rogue scientists do exist, and when we sacrifice morals for progress, we often end up with neither.