Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings? A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.

     Once one of Silicon Valley’s greatest success stories, Facebook has been under constant fire for the past five years, roiled by controversies and crises. It turns out that while the tech giant was connecting the world, they were also mishandling users’ data, spreading fake news, and amplifying dangerous, polarizing hate speech. The company, many said, had simply lost its way. But the truth is far more complex. Leadership decisions enabled, and then attempted to deflect attention from, the crises. Time after time, Facebook’s engineers were instructed to create tools that encouraged people to spend as much time on the platform as possible, even as those same tools boosted inflammatory rhetoric, conspiracy theories, and partisan filter bubbles. And while consumers and lawmakers focused their outrage on privacy breaches and misinformation, Facebook solidified its role as the world’s most voracious data-mining machine, posting record profits, and shoring up its dominance via aggressive lobbying efforts. Drawing on their unrivaled sources, Sheera Frenkel and Cecilia Kang take readers inside the complex court politics, alliances and rivalries within the company to shine a light on the fatal cracks in the architecture of the tech behemoth. Their explosive, exclusive reporting led them to a shocking conclusion: The missteps of the last five years were not an anomaly but an inevitability—this is how Facebook was built to perform. In a period of great upheaval, growth has remained the one constant under the leadership of Mark Zuckerberg and Sheryl Sandberg. Both have been held up as archetypes of uniquely 21st century executives—he the tech “boy genius” turned billionaire, she the ultimate woman in business, an inspiration to millions through her books and speeches. But sealed off in tight circles of advisers and hobbled by their own ambition and hubris, each has stood by as their technology is coopted by hate-mongers, criminals and corrupt political regimes across the globe, with devastating consequences. In An Ugly Truth, they are at last held accountable.

    Her work has influenced filmmakers (the Tree of Souls of James Cameron's Avatar) and her TED talks have been viewed by more than 10 million people worldwide.Now, in her first book, Simard brings us into her world, the intimate world of the trees, in which she brilliantly illuminates the fascinating and vital truths--that trees are not simply the source of timber or pulp, but are a complex, interdependent circle of life; that forests are social, cooperative creatures connected through underground networks by which trees communicate their vitality and vulnerabilities with communal lives not that different from our own.Simard writes--in inspiring, illuminating, and accessible ways--how trees, living side by side for hundreds of years, have evolved, how they perceive one another, learn and adapt their behaviors, recognize neighbors, and remember the past; how they have agency about the future; elicit warnings and mount defenses, compete and cooperate with one another with sophistication, characteristics ascribed to human intelligence, traits that are the essence of civil societies--and at the center of it all, the Mother Trees: the mysterious, powerful forces that connect and sustain the others that surround them.Simard writes of her own life, born and raised into a logging world in the rainforests of British Columbia, of her days as a child spent cataloging the trees from the forest and how she came to love and respect them--embarking on a journey of discovery, and struggle. And as she writes of her scientific quest, she writes of her own journey--of love and loss, of observation and change, of risk and reward, making us understand how deeply human scientific inquiry exists beyond data and technology, that it is about understanding who we are and our place in the world, and, in writing of her own life, we come to see the true connectedness of the Mother Tree that nurtures the forest in the profound ways that families and human societies do, and how these inseparable bonds enable all our survival.

    But they all made a significant contribution to the cultural and intellectual history of America and ultimately changed the course of the twentieth century, in spite of the men who often undervalued or dismissed their work. These ten women—Dorothy Parker, Rebecca West, Hannah Arendt, Mary McCarthy, Susan Sontag, Pauline Kael, Joan Didion, Nora Ephron, Renata Adler, and Janet Malcolm—are united by what Dean calls “sharpness,” the ability to cut to the quick with precision of thought and wit. Sharp is a vibrant depiction of the intellectual beau monde of twentieth-century New York, where gossip-filled parties at night gave out to literary slugging-matches in the pages of the Partisan Review or the New York Review of Books. It is also a passionate portrayal of how these women asserted themselves through their writing in a climate where women were treated with extreme condescension by the male-dominated cultural establishment. Mixing biography, literary criticism, and cultural history, Sharp is a celebration of this group of extraordinary women, an engaging introduction to their works, and a testament to how anyone who feels powerless can claim the mantle of writer, and, perhaps, change the world.

    Dave Goulson has always been obsessed with wildlife, from his childhood menagerie of exotic pets and dabbling in experimental taxidermy to his groundbreaking research into the mysterious ways of the bumblebee and his mission to protect our rarest bees. Once commonly found in the marshes of Kent, the short-haired bumblebee now only exists in the wilds of New Zealand, the descendants of a few queen bees shipped over in the nineteenth century. Dave Goulson's passionate drive to reintroduce it to its native land is one of the highlights of a book that includes exclusive research into these curious creatures, history's relationship with the bumblebee and advice on how to protect it for all time. One of the UK's most respected conservationists and the founder of the Bumblebee Conservation Trust, Goulson combines Gerald Durrell-esque tales of a child's growing passion for nature with a deep insight into the crucial importance of the bumblebee. He details the minutiae of life in their nests, sharing fascinating research into the effects intensive farming has had on our bee populations and on the potential dangers if we are to continue down this path.

    Explaining why the whole is sometimes smarter than the sum of its parts, Johnson presents surprising examples of feedback, self-organization, and adaptive learning. How does a lively neighborhood evolve out of a disconnected group of shopkeepers, bartenders, and real estate developers? How does a media event take on a life of its own? How will new software programs create an intelligent World Wide Web? In the coming years, the power of self-organization -- coupled with the connective technology of the Internet -- will usher in a revolution every bit as significant as the introduction of electricity. Provocative and engaging, Emergence puts you on the front lines of this exciting upheaval in science and thought.

    Although there are more than thirty thousand species of fish—more than all mammals, birds, reptiles, and amphibians combined—we rarely consider how individual fishes think, feel, and behave. Balcombe upends our assumptions about fishes, portraying them not as unfeeling, dead-eyed feeding machines but as sentient, aware, social, and even Machiavellian—in other words, much like us. What a Fish Knows draws on the latest science to present a fresh look at these remarkable creatures in all their breathtaking diversity and beauty. Fishes conduct elaborate courtship rituals and develop lifelong bonds with shoalmates. They also plan, hunt cooperatively, use tools, curry favor, deceive one another, and punish wrongdoers. We may imagine that fishes lead simple, fleeting lives—a mode of existence that boils down to a place on the food chain, rote spawning, and lots of aimless swimming. But, as Balcombe demonstrates, the truth is far richer and more complex, worthy of the grandest social novel. Highlighting breakthrough discoveries from fish enthusiasts and scientists around the world and pondering his own encounters with fishes, Balcombe examines the fascinating means by which fishes gain knowledge of the places they inhabit, from shallow tide pools to the deepest reaches of the ocean. Teeming with insights and exciting discoveries, What a Fish Knows offers a thoughtful appraisal of our relationships with fishes and inspires us to take a more enlightened view of the planet’s increasingly imperiled marine life. What a Fish Knows will forever change how we see our aquatic cousins—the pet goldfish included.

    Thrown into a profession of gallows humor and vivid characters (both living and very dead), Caitlin learned to navigate the secretive culture of those who care for the deceased.Smoke Gets in Your Eyes tells an unusual coming-of-age story full of bizarre encounters and unforgettable scenes. Caring for dead bodies of every color, shape, and affliction, Caitlin soon becomes an intrepid explorer in the world of the dead. She describes how she swept ashes from the machines (and sometimes onto her clothes) and reveals the strange history of cremation and undertaking, marveling at bizarre and wonderful funeral practices from different cultures.Her eye-opening, candid, and often hilarious story is like going on a journey with your bravest friend to the cemetery at midnight. She demystifies death, leading us behind the black curtain of her unique profession. And she answers questions you didn’t know you had: Can you catch a disease from a corpse? How many dead bodies can you fit in a Dodge van? What exactly does a flaming skull look like?Honest and heartfelt, self-deprecating and ironic, Caitlin's engaging style makes this otherwise taboo topic both approachable and engrossing. Now a licensed mortician with an alternative funeral practice, Caitlin argues that our fear of dying warps our culture and society, and she calls for better ways of dealing with death (and our dead).

    Harvey Washington Wiley, who fought for change.By the end of nineteenth century, food was dangerous. Lethal, even. "Milk" might contain formaldehyde, most often used to embalm corpses. Decaying meat was preserved with both salicylic acid, a pharmaceutical chemical, and borax, a compound first identified as a cleaning product. This was not by accident; food manufacturers had rushed to embrace the rise of industrial chemistry, and were knowingly selling harmful products. Unchecked by government regulation, basic safety, or even labelling requirements, they put profit before the health of their customers. By some estimates, in New York City alone, thousands of children were killed by "embalmed milk" every year. Citizens--activists, journalists, scientists, and women's groups--began agitating for change. But even as protective measures were enacted in Europe, American corporations blocked even modest regulations. Then, in 1883, Dr. Harvey Washington Wiley, a chemistry professor from Purdue University, was named chief chemist of the agriculture department, and the agency began methodically investigating food and drink fraud, even conducting shocking human tests on groups of young men who came to be known as, "The Poison Squad."Over the next thirty years, a titanic struggle took place, with the courageous and fascinating Dr. Wiley campaigning indefatigably for food safety and consumer protection. Together with a gallant cast, including the muckraking reporter Upton Sinclair, whose fiction revealed the horrific truth about the Chicago stockyards; Fannie Farmer, then the most famous cookbook author in the country; and Henry J. Heinz, one of the few food producers who actively advocated for pure food, Dr. Wiley changed history. When the landmark 1906 Food and Drug Act was finally passed, it was known across the land, as "Dr. Wiley's Law."Blum brings to life this timeless and hugely satisfying "David and Goliath" tale with righteous verve and style, driving home the moral imperative of confronting corporate greed and government corruption with a bracing clarity, which speaks resoundingly to the enormous social and political challenges we face today.

    The instinct to fight may be innate in human nature, but war—organized violence—comes with organized society. War has shaped humanity’s history, its social and political institutions, its values and ideas. Our very language, our public spaces, our private memories, and some of our greatest cultural treasures reflect the glory and the misery of war. War is an uncomfortable and challenging subject not least because it brings out both the vilest and the noblest aspects of humanity. Margaret MacMillan looks at the ways in which war has influenced human society and how, in turn, changes in political organization, technology, or ideologies have affected how and why we fight. War: How Conflict Shaped Us explores such much-debated and controversial questions as: When did war first start? Does human nature doom us to fight one another? Why has war been described as the most organized of all human activities? Why are warriors almost always men? Is war ever within our control? Drawing on lessons from wars throughout the past, from classical history to the present day, MacMillan reveals the many faces of war—the way it has determined our past, our future, our views of the world, and our very conception of ourselves.

    And before there were fish in the sea, there were cephalopods - the ancestors of modern squid and Earth’s first truly substantial animals. Cephalopods became the first creatures to rise from the seafloor, essentially inventing the act of swimming. With dozens of tentacles and formidable shells, they presided over an undersea empire for millions of years. But when fish evolved jaws, the ocean’s former top predator became its most delicious snack. Cephalopods had to step up their game. Many species streamlined their shells and added defensive spines, but these enhancements only provided a brief advantage. Some cephalopods then abandoned the shell entirely, which opened the gates to a flood of evolutionary innovations: masterful camouflage, fin-supplemented jet propulsion, perhaps even dolphin-like intelligence. Squid Empire is an epic adventure spanning hundreds of millions of years, from the marine life of the primordial ocean to the calamari on tonight’s menu. Anyone who enjoys the undersea world—along with all those obsessed with things prehistoric—will be interested in the sometimes enormous, often bizarre creatures that ruled the seas long before the first dinosaurs.

    She introduces us to renowned futurists like Stewart Brand and scientists like George Church, who are harnessing the powers of CRISPR gene editing in the hopes of “reviving” extinct passenger pigeons, woolly mammoths, and heath hens. She speaks with Nikita Zimov, who together with his eclectic father Sergey, is creating Siberia’s Pleistocene Park—a daring attempt to rebuild the mammoth’s ancient ecosystem in order to save earth from climate apocalypse. Through interviews with these and other thought leaders, Wray reveals the many incredible opportunities for research and conservation made possible by this emerging new field.But we also hear from more cautionary voices, like those of researcher and award-winning author Beth Shapiro (How to Clone a Woolly Mammoth) and extinction philosopher Thomas van Dooren. Writing with passion and perspective, Wray delves into the larger questions that come with this incredible new science, reminding us that de-extinction could bring just as many dangers as it does possibilities. What happens, for example, when we bring an “unextinct” creature back into the wild? How can we care for these strange animals and ensure their comfort and safety—not to mention our own? And what does de-extinction mean for those species that are currently endangered? Is it really ethical to bring back an extinct passenger pigeon, for example, when countless other birds today will face the same fate?By unpacking the many biological, technological, ethical, environmental, and legal questions raised by this fascinating new field, Wray offers a captivating look at the best and worst of resurrection science.

    In Darwin Comes to Town, evolutionary biologist Menno Schilthuizen shows that evolution can in fact happen extremely quickly, and in the strangest of places: the heart of the city.Menno Schilthuizen is one of a growing number of “urban ecologists” studying how our manmade environments are accelerating the evolution of the animals and plants around us. Cities are extreme environments and, in a world of adapt or die, the wildlife sharing these spaces with us is being forced to adopt fascinating new ways of surviving, and often thriving.--Carrion crows in the Japanese city of Sendai have learned to use passing traffic to crack nuts.--Spiders in Vienna are adapting to build their webs near moth-attracting streetlights, while moths in some cities are developing a resistance to the lure of light bulbs.--Certain Puerto Rican city lizards are evolving feet that better grip surfaces like concrete.--Europe’s urban blackbirds sing at a higher pitch than their rural cousins, to be heard over the din of traffic, while many pigeons have eschewed traveling “as the crow flies” in favor of following manmade roads.Darwin Comes to Town draws on these and other eye-popping examples to share a stunning vision of urban evolution in which humans and wildlife co-exist in a unique harmony. It reveals that evolution can happen far more rapidly than Darwin dreamed, while providing a glimmer of hope that our race toward overpopulation might not take the rest of nature down with us.

    To the right listener, they tell us all about themselves: where they came from, how they lived, how they died - and who killed them. Forensic scientists can unlock the mysteries of the past and help justice to be done using the messages left by a corpse, a crime scene or the faintest of human traces. Forensics uncovers the secrets of forensic medicine, drawing on interviews with top-level professionals, ground-breaking research and Val McDermid's own experience to lay bare the secrets of this fascinating science. And, along the way, she wonders at how maggots collected from a corpse can help determine time of death, how a DNA trace a millionth the size of a grain of salt can be used to convict a killer and how a team of young Argentine scientists led by a maverick American anthropologist uncovered the victims of a genocide.In her crime novels, Val McDermid has been solving complex crimes and confronting unimaginable evil for years. Now, she's looking at the people who do it for real, and real crime scenes. It's a journey that will take her to war zones, fire scenes and autopsy suites, and bring her into contact with extraordinary bravery and wickedness, as she traces the history of forensics from its earliest beginnings to the cutting-edge science of the modern day.

    Among the most compelling and perplexing of these symptoms are the strange visual hallucinations and distortions of space, time, and body image which migraineurs sometimes experience. Portrayals of these uncanny states have found their way into many works of art, from the heavenly visions of Hildegard von Bingen to Alice in Wonderland. Dr. Oliver Sacks argues that migraine cannot be understood simply as an illness, but must be viewed as a complex condition with a unique role to play in each individual's life.