That substance is vitamin D3. While it is called a vitamin, D3 is really a hormone. It was first used to treat a childhood bone disease called rickets. And, nearly all the research on the benefits of vitamin D3 has been done at doses that are 80 times lower than the optimal doses described in this book. This ground-breaking book is your opportunity to regain your health quickly, safely and easily. In The Optimal Dose, he reveals how vitamin D3 saved his own life when all else failed and explains how this essential vitamin is key to finding answers to your own health questions and challenges.

    

    While maintaining the hallmark features of previous editions, the Fourth Edition has been completely updated. It includes new Key Concepts at the beginning of each chapter and annotated further reading at the conclusion of each chapter, to help readers navigate the wealth of information in this subject.The text has been restructured so genomic technologies are integrated throughout, and next generation sequencing is included. Genetic testing, screening, approaches to therapy, personalized medicine, and disease models have been brought together in one section. Coverage of cell biology including stem cells and cell therapy, studying gene function and structure, comparative genomics, model organisms, noncoding RNAs and their functions, and epigenetics have all been expanded.

    This fascinating collection of historical curiosities explores some of the strangest cases that have perplexed doctors across the world.From seventeenth-century Holland to Tsarist Russia, from rural Canada to a whaler in the Pacific, many are monuments to human stupidity – such as the sailor who swallowed dozens of penknives to amuse his shipmates, or the chemistry student who in 1850 arrived at a hospital in New York with his penis trapped inside a bottle, having unwisely decided to relieve himself into a vessel containing highly reactive potassium. Others demonstrate exceptional surgical ingenuity long before the advent of anaesthesia – such as a daring nineteenth-century operation to remove a metal fragment from beneath a conscious patient’s heart. We also hear of the weird, often hilarious remedies employed by physicians of yore – from crow’s vomit to port-wine enemas – the hazards of such everyday objects as cucumbers and false teeth, and miraculous recovery from apparently terminal injuries.

     In this masterful account of the 1995 Ebola outbreak in Zaire, Garrett, now the Senior Fellow for Global Health at the Council on Foreign Relations, shows how superstition and fear, compounded by a lack of resources, education, and clearheaded government planning have plagued our response to Ebola. In an extensive new introduction, Garrett forcefully argues that learning from past outbreaks is the key to solving the Ebola crisis of 2014. In her account of the 1995 Zaire outbreak, first published in her bestselling book Betrayal of Trust, Garrett takes readers through the epidemic's course-beginning with the Kikwit villager who first contracted it from an animal encounter while chopping wood for charcoal deep in the forest. As she documents the outbreak in riveting detail, Garrett shows why our trust in world governments to protect people's health has been irrevocably broken. She details the international community's engagement in the epidemic's aftermath: a pattern of response and abandonment, urgency that devolves into amnesia. Ebola: Story of an Outbreak is essential reading for anyone who wants to comprehend Ebola, one of mankind's most mysterious, malicious scourges. Garrett has issued a powerful call for governments, citizens, and the disease-fighting agencies of the wealthy world to take action.

    Unlocking the secrets of our genomes opens the door to understanding why we are the way we are and potentially fixing what ails us, from cancer and diabetes to obesity and male pattern baldness. But what exactly will happen to this information? Will it be a boon or just another marketing tool?Here Is a Human Being is the first in-depth look at personal genomics—its larger-than-life research subjects; its entrepreneurs and do-it-yourselfers; its technology developers; and the bewildered physicians and regulators who must negotiate with it—and what it means to be a “public genome” in a world where privacy is already under siege.

    While some bacteria and viruses can make us sick, normally we coexist peacefully with microbes. In fact, they are essential to our everyday health. Microbes help break down food in the digestive tract, support immune function and protect us from the pathogens we come into contact with on a daily basis. Our well-being is intimately tied to the microbes that surround us—on our cellphones, kitchen sponges, houseplants, pets and desks.In this groundbreaking volume, the authors present current and emerging research on microbial interventions for the full gamut of age-related conditions, from sun spots and wrinkles to Alzheimer’s disease, cancer, osteoporosis, menopause, chronic inflammation and more. The good news is that simple changes to nutrition and lifestyle can promote the right kind of microbial exposure, to improve health whether we’re eighteen or eighty.Incorporating interviews with leading microbiologists, scientific researchers and medical professionals, and with a compelling and proactive approach to cutting-edge science, The Whole-Body Microbiome will appeal to anyone looking to grow old as healthfully and gracefully as possible.

    They’ve tested France’s first guillotines, ridden the NASA Space Shuttle, been crucified in a Parisian laboratory to test the authenticity of the Shroud of Turin, and helped solve the mystery of TWA Flight 800. For every new surgical procedure, from heart transplants to gender confirmation surgery, cadavers have helped make history in their quiet way. “Delightful—though never disrespectful” (Les Simpson, Time Out New York), Stiff investigates the strange lives of our bodies postmortem and answers the question: What should we do after we die?“This quirky, funny read offers perspective and insight about life, death and the medical profession. . . . You can close this book with an appreciation of the miracle that the human body really is.” —Tara Parker-Pope, Wall Street Journal“Gross, educational, and unexpectedly sidesplitting.” —Entertainment Weekly

    Great care has been taken to select important concepts and to perfectly describe the anatomy of cells, organs, and organ systems. The plan that has been followed for eight editions of this text is to combine clear and accurate descriptions of anatomy with precise explanations of how structures function and examples of how they work together to maintain life. To emphasize the concepts of anatomy and physiology, the authors provide explanations of how the systems respond to aging, changes in physical activity, and disease, with a special focus on homeostasis and the regulatory mechanisms that maintain it. Timely and interesting examples demonstrate the application of knowledge in a clinical context.

    The implications of their discoveries form tomorrow's headlines, yet Angier writes about the scientists themselves and not merely theri successes. 4-page photo insert.

    Lyme disease, and SARS. According to Walters, we are not only victims of these emerging diseases; we are helping exacerbate their creation and spread.

    Adam Brochert, MD-who scored in the 99th percentile on the Step 2 USMLE-and Theodore X. O'Connell, MD-author of several review and clinical reference books-present essential questions and answers covering the important concepts you need to know to score well on the USMLE Step 2 exam: key conditions you will be expected to recognize, all specialty and subspecialty topics, and necessary clinical concepts.Learn the most important questions and answers with the proven format of the highly acclaimed Secrets Series.Master all specialty and subspecialty topics covered on Step 2.Identify key facts and secrets using the Top 100 Secrets chapter.Review material quickly and easily thanks to bulleted lists, algorithms, and illustrations.Apply the pearls, tips, memory aids, and secrets from well-known and highly popular authors, Adam Brochert, MD and Theodore X. O'Connell, MD. Find information quickly with a second color highlighting chapter and section titles, legends, bullets and icons, and key terms.Consult the book wherever you go thanks to the portable size that fits in your lab coat pocket.

    Through them we are able to uncover new information concerning the genetic and environmental factors affecting who we are. Studies using identical and fraternal twins hold the keys to understanding our intellectual abilities, personality traits, social attitudes, and behavior. In Entwined Lives, Dr. Nancy Segal brings together cutting-edge information with illustrative case histories of twins and their families. In addition to the fascinating stories of identical twins reared apart and reunited as adults, Dr. Segal provides insights into the unusual language patterns of twins, how twin studies affect legal decisions, the role of fertility treatments in twin and "twinlike" conceptions, and more. This groundbreaking book explores the ways in which twins enhance our knowledge of human behavioral and physical development, while shedding new light on the nature/nurture debate and on the burgeoning field of evolutionary psychology.

    Desowitz asks, has biotechnical research on malaria produced so little when it had promised so much? An expert in tropical diseases, Desowtiz searches for answers in this provocative book.

    Complications lays bare a science not in its idealized form but as it actually is--uncertain, perplexing, and profoundly human.Complications is a 2002 National Book Award Finalist for Nonfiction.