Two men, known in medical journals as the Berlin Patients, revealed answers to a functional cure for HIV. Their cures came twelve years apart, the first in 1996 and the second in 2008. Each received his own very different treatment in Berlin, Germany, and each result spurred a new field of investigation, fueling innovative lines of research and sparking hope for the thirty-four million people currently infected with HIV. For the first time, Nathalia Holt, who has participated in some of the most fruitful research in the field, tells the story of how we came to arrive at this astounding and controversial turning point. Holt explores the two men’s stories on a personal level, looking at how their experiences have influenced HIV researchers worldwide—including one very special young family doctor who took the time to look closely at his patients—and how they responded to their medications. Based on extensive interviews with the patients and their doctors as well as her own in-depth research, this book is an unprecedented look at how scientists pursue their inquiries, the human impact their research has, and what is and is not working in the relationship between Big Pharma and medical care.

    "An intellectually dazzling view of our past and future."--Time magazineContents1. How humans have repeatedly lost hope, and how new encounters, and a new pair of spectacles, revive them2. How men and women have slowly learned to have interesting conversations3. How people searching for their roots are only beginning to look far and deep enough4. How some people have acquired an immunity to loneliness5. How new forms of love have been invented6. Why there has been more progress in cooking than in sex7. How the desire that men feel for women, and for other men, has altered through the centuries8. How respect has become more desirable than power9. How those who want neither to give orders nor to receive them can become intermediaries10. How people have freed themselves from fear by finding new fears11. How curiosity has become the key to freedom12. Why it has become increasingly difficult to destroy one’s enemies13. How the art of escaping from one’s troubles has developed, but not the art of knowing where to escape to14. Why compassion has flowered even in stony ground15. Why toleration has never been enough16. Why even the privileged are often somewhat gloomy about life, even when they can have anything the consumer society offers, and even after sexual liberation17. How travellers are becoming the largest nation in the world, and how they have learned not to see only what they are looking for18. Why friendship between men and women has been so fragile19. How even astrologers resist their destiny20. Why people have not been able to find the time to lead several lives21. Why fathers and their children are changing their minds about what they want from each other22. Why the crisis in the family is only one stage in the evolution of generosity23. How people choose a way of life, and how it does not wholly satisfy them24. How humans become hospitable to each other25. What becomes possible when soul-mates meet

    We are now all too aware of how it is applied, but we know far less about how the idea came to be--and where it may yet go.Until Proven Safe tracks the idea of quarantine around the globe, through time and space, chasing the story from the lazarettos and quarantine islands of Venice--built before communicable diseases were really understood--to the hallways of the CDC, NASA, and the cutting-edge labs and conference rooms where the future technology of quarantine is being developed. The result is a tour of an idea that could not be more urgent or relevant, a book full of stories, people, and insights that is as compelling as it is definitive.

    To tell the story of the twentieth century without reference to this drug and its contribution is to miss a vital and fascinating strand of social history. Streatfeild examines the story of cocaine from its first medical uses to the worldwide chaos it causes today. His research takes him from the arcane reaches of the British Library to the isolation cells of America's most secure prisons; from the crackhouses of New York to the jungles of Bolivia and Colombia.