As the mosquito transformed the landscapes of civilization, humans were unwittingly required to respond to its piercing impact and universal projection of power.The mosquito has determined the fates of empires and nations, razed and crippled economies, and decided the outcome of pivotal wars, killing nearly half of humanity along the way. She (only females bite) has dispatched an estimated 52 billion people from a total of 108 billion throughout our relatively brief existence. As the greatest purveyor of extermination we have ever known, she has played a greater role in shaping our human story than any other living thing with which we share our global village.Imagine for a moment a world without deadly mosquitoes, or any mosquitoes, for that matter? Our history and the world we know, or think we know, would be completely unrecognizable.Driven by surprising insights and fast-paced storytelling, The Mosquito is the extraordinary untold story of the mosquito's reign through human history and her indelible impact on our modern world order.

    The Barbary Plague transports us to the Gold Rush boomtown in 1900, at the end of the city’s Gilded Age. With a deep understanding of the effects on public health of politics, race, and geography, Chase shows how one city triumphed over perhaps the most frightening and deadly of all scourges.

    One day, while Guerrero was at school, her undocumented immigrant parents were taken from their home, detained, and deported. Guerrero's life, which had been full of the support of a loving family, was turned upside down.

    What he discovered is a revolution under way—an explosion of new ideas about what cancer really is and where it comes from. In a provocative and intellectually vibrant exploration, he takes us on an adventure through the history and recent advances of cancer research that will challenge everything you thought you knew about the disease. Deftly excavating and illuminating decades of investigation and analysis, he reveals what we know and don’t know about cancer, showing why a cure remains such a slippery concept. We follow him as he combs through the realms of epidemiology, clinical trials, laboratory experiments, and scientific hypotheses—rooted in every discipline from evolutionary biology to game theory and physics. Cogently extracting fact from a towering canon of myth and hype, he describes tumors that evolve like alien creatures inside the body, paleo-oncologists who uncover petrified tumors clinging to the skeletons of dinosaurs and ancient human ancestors, and the surprising reversals in science’s comprehension of the causes of cancer, with the foods we eat and environmental toxins playing a lesser role. Perhaps most fascinating of all is how cancer borrows natural processes involved in the healing of a wound or the unfolding of a human embryo and turns them, jujitsu-like, against the body. Throughout his pursuit, Johnson clarifies the human experience of cancer with elegiac grace, bearing witness to the punishing gauntlet of consultations, surgeries, targeted therapies, and other treatments. He finds compassion, solace, and community among a vast network of patients and professionals committed to the fight and wrestles to comprehend the cruel randomness cancer metes out in his own family. For anyone whose life has been affected by cancer and has found themselves asking why?, this book provides a new understanding. In good company with the works of Atul Gawande, Siddhartha Mukherjee, and Abraham Verghese, The Cancer Chronicles is endlessly surprising and as radiant in its prose as it is authoritative in its eye-opening science.

    With time running out, Christopher must use every skill he’s learned to discover the key to a terrible secret with the power to tear the world apart.

    The more experiments you make the better."Before Ralph Waldo Emerson was a great writer, he was a city boy who longed for the broad, open fields and deep, still woods of the country, and then a young man who treasured books, ideas, and people. When he grew up and set out in the world, he wondered, could he build a life around these things he loved?This moving biography--presented with Barbara Kerley and Edwin Fotheringham's inimitable grace and style--illustrates the rewards of a life well-lived, one built around personal passions: creativity and community, nature and friendship.May it inspire you to experiment and build the life you dream of living.

    For the next three years, he would face the horrors of war as a black soldier in a segregated army. He endured the terrible lies white officers told about the black soldiers to isolate them from anyone who showed kindness—including each other. He received worse treatment than even Nazi POWs. He was assigned the grimmest, most horrific tasks, like burying fallen soldiers…but was told to remove the black soldiers first because the media didn’t want them in their newsreels. And he waited and wanted so desperately to go home, watching every white soldier get safe passage back to the United States before black soldiers were even a thought. For the next forty years, Ashley would keep his time in the war a secret. But now, he tells his story. The story of the kind people who supported him. The story of the bright moments that guided him through the dark. And the story of his passion for art that would save him time and time again. Filled with never-before-seen artwork and handwritten letters and diary entries, this illuminating and moving memoir by Newbery Honor–winning illustrator Ashley Bryan is both a lesson in history and a testament to hope.

    Thirteen-year-old Issy McKelvie leaves school and starts her first job - very reluctantly - as a maid in an undertaking establishment. She thinks this is about as low as you can go. But there's worse to come. Issy becomes an unwilling rat-catcher when the plague - the Black Death - arrives in Australia. Issy loathes both rats and her father's four yappy, snappy, hyperactive rat-killing terriers. But when her father becomes ill it's up to Issy to join the battle to rid the city of the plague-carrying rats. Ages 10+

    Next comes ice like panes of glass. And eventually, skating ice! Take a literary skate over field ice and streambed, through sleeping orchards and beyond. The first ice, the second ice, the third ice . . . perfect ice . . . the last ice . . . Twelve kinds of ice are carved into twenty nostalgic vignettes, illustrated in elegantly scratched detail by the award-winning Barbara McClintock.

    But plenty of excitement (and shocks) are coming Jack's way once his mom loans him out to help a feisty old neighbor with a most unusual chore—typewriting obituaries filled with stories about the people who founded his Utopian town. As one obituary leads to another, Jack is launched on a strange adventure involving molten wax, Eleanor Roosevelt, twisted promises, a homemade airplane, Girl Scout cookies, a man on a trike, a dancing plague, voices from the past, Hells Angels . . . and possibly murder. Endlessly surprising, this sly, sharp-edged narrative is the author at his very best, making readers laugh out loud at the most unexpected things in a dead-funny depiction of growing up in a slightly off-kilter place where the past is present, the present is confusing, and the future is completely up in the air.

    At first things went smoothly for the Clinton 12, but then outside agitators interfered, pitting the townspeople against one another. Uneasiness turned into anger, and even the Clinton Twelve themselves wondered if the easier thing to do would be to go back to their old school. Jo Ann--clear-eyed, practical, tolerant, and popular among both black and white students---found herself called on as the spokesperson of the group. But what about just being a regular teen? This is the heartbreaking and relatable story of her four months thrust into the national spotlight and as a trailblazer in history. Based on original research and interviews and featuring backmatter with archival materials and notes from the authors on the co-writing process.

    Happy picnic-goers headed for an employee outing across Lake Michigan suddenly found themselves in a struggle for their lives. Trapped belowdecks, crushed by the crowds attempting to escape the rising waters, or hurled into the river from the upper deck of the ship, roughly one-third of the passengers, mostly women and children, perished that day.       The Eastland disaster took more passenger lives than the Titanic and stands today as the greatest loss of life on the Great Lakes. Capsized! details the events leading up to the fateful day and provides a nail-biting, minute-by-minute account of the ship's capsizing. From the courage of the survivors to the despair of families who lost loved ones, author Patricia Sutton brings to light the stories of ordinary working people enduring the unthinkable.      Capsized! also raises critical-thinking questions for young readers: Why do we know so much about the Titanic's sinking yet so little about the Eastland disaster? What causes a tragedy to be forgotten and left out of society's collective memory? And what lessons from this disaster might we be able to apply today?

    From the conquest of Mexico by smallpox as much as by the Spanish, to the bubonic plague in China, to the typhoid epidemic in Europe, the history of disease is the history of humankind. With the identification of AIDS in the early 1980s, another chapter has been added to this chronicle of events, which William McNeill explores in his new introduction to this updated editon.Thought-provoking, well-researched, and compulsively readable, Plagues and Peoples is that rare book that is as fascinating as it is scholarly, as intriguing as it is enlightening. "A brilliantly conceptualized and challenging achievement" (Kirkus Reviews), it is essential reading, offering a new perspective on human history.

    But which one? And how?Over the past fifty years, more than three hundred infectious diseases have either newly emerged or reemerged, appearing in territories where they’ve never been seen before. Ninety percent of epidemiologists expect that one of them will cause a deadly pandemic sometime in the next two generations. It could be Ebola, avian flu, a drug-resistant superbug, or something completely new. While we can’t know which pathogen will cause the next pandemic, by unraveling the story of how pathogens have caused pandemics in the past, we can make predictions about the future. In Pandemic: Tracking Contagions, from Cholera to Ebola and Beyond, the prizewinning journalist Sonia Shah—whose book on malaria, The Fever, was called a “tour-de-force history” (The New York Times) and “revelatory” (The New Republic)—interweaves history, original reportage, and personal narrative to explore the origins of contagions, drawing parallels between cholera, one of history’s most deadly and disruptive pandemic-causing pathogens, and the new diseases that stalk humankind today.To reveal how a new pandemic might develop, Sonia Shah tracks each stage of cholera’s dramatic journey, from its emergence in the South Asian hinterlands as a harmless microbe to its rapid dispersal across the nineteenth-century world, all the way to its latest beachhead in Haiti. Along the way she reports on the pathogens now following in cholera’s footsteps, from the MRSA bacterium that besieges her own family to the never-before-seen killers coming out of China’s wet markets, the surgical wards of New Delhi, and the suburban backyards of the East Coast.By delving into the convoluted science, strange politics, and checkered history of one of the world’s deadliest diseases, Pandemic reveals what the next global contagion might look like— and what we can do to prevent it.

    Your brain can't function. You are asked to make decisions about treatment almost immediately, when you are not in your right mind. And yet you pull yourself together and start asking questions. Beside you is your doctor, whose job it is to solve the awful puzzle of bone marrow gone wrong. The two of you are in it together. In When Blood Breaks Down, Mikkael Sekeres, a leading cancer specialist, takes readers on the journey that patient and doctor travel together.Sekeres, who writes regularly for the Well section of the New York Times, tells the compelling stories of three people who receive diagnoses of adult leukemia within hours of each other: Joan, a 48-year-old surgical nurse, a caregiver who becomes a patient; David, a 68-year-old former factory worker who bows to his family's wishes and pursues the most aggressive treatment; and Sarah, a 36-year-old pregnant woman who must decide whether to undergo chemotherapy and put her fetus at risk. We join the intimacy of the conversations Sekeres has with his patients, and watch as he teaches trainees. Along the way, Sekeres also explores leukemia in its different forms and the development of drugs to treat it--describing, among many other fascinating details, the invention of the bone marrow transplant (first performed experimentally on beagles) and a treatment that targets the genetics of leukemia.The lessons to be learned from leukemia, Sekeres shows, are not merely medical; they teach us about courage and grace and defying the odds.