Jennifer White's best friend, Amanda, is found dead with four of her fingers surgically removed, Dr. White is the prime suspect. But she herself doesn't know whether she did it. Told in White's own voice, fractured and eloquent, a picture emerges of the surprisingly intimate, complex alliance between these life-long friends—two proud, forceful women who were at times each other's most formidable adversary. As the investigation into the murder deepens and White's relationships with her live-in caretaker and two grown children intensify, a chilling question lingers: is White's shattered memory preventing her from revealing the truth or helping her to hide it? A startling portrait of a disintegrating mind clinging to bits of reality through anger, frustration, shame, and unspeakable loss, Turn of Mind is a remarkable debut that examines the deception and frailty of memory and how it defines our very existence.

    But when athletic Chloé suddenly drowns, Gabriel is left to grapple with the mysterious circumstances of her death. Brokenhearted, he pours out his grief in a bereavement group and is consoled by photographer Emma. While the two grow closer, Gabriel can’t help but feel Chloé’s presence everywhere he goes. And as revelations about Chloé slowly emerge, he begins to wonder, is Emma really that different?From prize-winning and bestselling author Amélie Antoine comes a dark and evocative novel that will keep readers guessing until the final moments—will Gabriel be able to move on with Emma, or will the mystery of Chloé’s death consume him?

    This is the startling theme of Philip Roth’s wrenching new book: a wartime polio epidemic in the summer of 1944 and the effect it has on a closely knit, family-oriented Newark community and its children. At the center of Nemesis is a vigorous, dutiful twenty-three-year-old playground director, Bucky Cantor, a javelin thrower and weightlifter, who is devoted to his charges and disappointed with himself because his weak eyes have excluded him from serving in the war alongside his contemporaries. Focusing on Cantor’s dilemmas as polio begins to ravage his playground—and on the everyday realities he faces—Roth leads us through every inch of emotion such a pestilence can breed: the fear, the panic, the anger, the bewilderment, the suffering, and the pain. Moving between the smoldering, malodorous streets of besieged Newark and Indian Hill, a pristine children’s summer camp high in the Poconos—whose “mountain air was purified of all contaminants”—Roth depicts a decent, energetic man with the best intentions struggling in his own private war against the epidemic. Roth is tenderly exact at every point about Cantor’s passage into personal disaster, and no less exact about the condition of childhood. Through this story runs the dark questions that haunt all four of Roth’s late short novels, Everyman, Indignation, The Humbling, and now Nemesis: What kind of accidental choices fatally shape a life? How does the individual withstand the onslaught of circumstance?

    Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with - and perished from - for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. From the Persian Queen Atossa, whose Greek slave cut off her malignant breast, to the nineteenth-century recipients of primitive radiation and chemotherapy to Mukherjee’s own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through fiercely demanding regimens in order to survive—and to increase our understanding of this iconic disease. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

    Conspiracies rule history. Jesuits plot against Freemasons. Italian republicans strangle priests with their own intestines. French criminals plan bombings by day and celebrate Black Masses at night. Every nation has its own secret service, perpetrating forgeries, plots, and massacres. From the unification of Italy to the Paris Commune to the Dreyfus Affair to The Protocols of the Elders of Zion, Europe is in tumult and everyone needs a scapegoat. But what if, behind all of these conspiracies both real and imagined, lay one lone man? What if that evil genius created its most infamous document?　 Eco takes his readers here on an unforgettable journey through the underbelly of world-shattering events. This is Eco at his most exciting, a book immediately hailed as his masterpiece.

    As the wait for his father stretches unforgivably into months, a local girl, whose own mother died a brutal death, captures his heart and imagination, reminding Wes that hope always floats to the surface.When buried truths come to light in the spring thaw, wounds are exposed and violence erupts, forcing Wes to embark on a search for his missing father, the truth about his mother, and a future he must claim for himself—a quest that begins back at that frozen lake.A powerful, page-turning coming-of-age story, Winter Loon captures the resilience of a boy determined to become a worthy man by confronting family demons, clawing his way out of the darkness, and forging a life from the shambles of a broken past.

    The curator is murdered at a clandestine meeting on the outskirts of Rome a week before it opens. That same night, a violent break-in rocks the home of Greek Catholic priest Father Alex Andreou. When the papal police fail to identify a suspect in either crime, Father Alex decides that to find the killer he must reconstruct the secret of what a little-known, true-to-life fifth gospel known as the Diatessaron reveals about the church’s most controversial holy relic. But just as he begins to understand the truth about his friend’s death and its consequences for the future of the Christian church, Father Alex discovers a ruthless stalker is hunting him—an enemy with a vested stake in the exhibit that he must outwit to survive.Rich, authentic, erudite, and emotionally searing, The Fifth Gospel is a riveting novel of suspense and a feast of biblical history that satisfies on every level.

    Preston Grind, she's just about out of options. She recently graduated from high school and is pregnant with her art teacher's baby. Her mother is dead and her father is a drunk. The art teacher is too much of a head-case to help raise the child. Izzy knows she can be a good mother but without any money or prospects, she's left searching.So when Dr. Grind offers her a space in The Infinite Family Project, she accepts. Housed in a spacious compound in Tennessee, she joins nine other couples, all with children the same age as her newborn son, to raise their children as one extended family. Grind's theory is that the more parental love a child receives, the better off they are.This attempt at a utopian ideal-funded by an eccentric billionaire-starts off promising: Izzy enjoys the kids, reading to them and teaching them to cook. She even forms a bond with her son more meaningful than she ever expected. But soon the gentle equilibrium among the families is upset and it all starts to disintegrate: unspoken resentments between the couples begin to fester; the project's funding becomes tenuous; and Izzy's feelings for Dr. Grind, who is looking to expunge his own painful childhood, make her question her participation in this strange experiment in the first place.Written with the same compassionate voice, disarming sense of humor, and quirky charm that made The Family Fang such a success, Perfect Little World is a poignant look at how the best families are the ones we make for ourselves.

    Siri and Jon have two daughters, and together they spend their summers on the coast of Norway, in a mansion belonging to Jenny Brodal, Siri’s stylish and unforgiving mother.Siri and Jon’s marriage is loving but difficult, and troubled by painful secrets. They have a strained relationship with their elder daughter, Alma, who struggles to find her place in the family constellation. When Milla is hired as a nanny to allow Siri to work her long hours at the restaurant and Jon to supposedly meet the deadline on his book, life in the idyllic summer community takes a dire turn. One rainy July night, Milla disappears without a trace. After her remains are discovered and a suspect is identified, everyone who had any connection with her feels implicated in her tragedy and haunted by what they could have done to prevent it.The Cold Song is a story about telling stories and about how life is continually invented and reinvented.

    In The Poisoner's Handbook Blum draws from highly original research to track the fascinating, perilous days when a pair of forensic scientists began their trailblazing chemical detective work, fighting to end an era when untraceable poisons offered an easy path to the perfect crime. Drama unfolds case by case as the heroes of The Poisoner's Handbook—chief medical examiner Charles Norris and toxicologist Alexander Gettler—investigate a family mysteriously stricken bald, Barnum and Bailey's Famous Blue Man, factory workers with crumbling bones, a diner serving poisoned pies, and many others. Each case presents a deadly new puzzle and Norris and Gettler work with a creativity that rivals that of the most imaginative murderer, creating revolutionary experiments to tease out even the wiliest compounds from human tissue. Yet in the tricky game of toxins, even science can't always be trusted, as proven when one of Gettler's experiments erroneously sets free a suburban housewife later nicknamed "America's Lucretia Borgia" to continue her nefarious work. From the vantage of Norris and Gettler's laboratory in the infamous Bellevue Hospital it becomes clear that killers aren't the only toxic threat to New Yorkers. Modern life has created a kind of poison playground, and danger lurks around every corner. Automobiles choke the city streets with carbon monoxide; potent compounds, such as morphine, can be found on store shelves in products ranging from pesticides to cosmetics. Prohibition incites a chemist's war between bootleggers and government chemists while in Gotham's crowded speakeasies each round of cocktails becomes a game of Russian roulette. Norris and Gettler triumph over seemingly unbeatable odds to become the pioneers of forensic chemistry and the gatekeepers of justice during a remarkably deadly time. A beguiling concoction that is equal parts true crime, twentieth-century history, and science thriller, The Poisoner's Handbook is a page-turning account of a forgotten New York.

    What was freedom, she thought, other than the right to exercise one's choices?Isabel Osmond, a spirited, intelligent young heiress, flees to London after being betrayed by her husband, to be with her beloved cousin Ralph on his deathbed. After a somber, silent existence at her husband's Roman palazzo, Isabel's daring departure to London reawakens her youthful quest for freedom and independence, as old suitors resurface and loyal friends remind her of happier times.But soon Isabel must decide whether to return to Rome to face up to the web of deceit in which she has become entangled or to strike out on her own once more.

    Rome, 1953: Hal, an itinerant journalist flailing in the post-war darkness, has come to the Eternal City to lose himself and to seek absolution for the thing that haunts him. One evening he finds himself on the steps of a palazzo, walking into a world of privilege and light. Here, on a rooftop above the city, he meets the mysterious Stella. Hal and Stella are from different worlds, but their connection is magnetic. Together, they escape the crowded party and imagine a different life, even if it's just for a night. Yet Stella vanishes all too quickly, and Hal is certain their paths won't cross again. But a year later they are unexpectedly thrown together, after Hal receives an invitation he cannot resist. An Italian Contessa asks him to assist on a trip of a lifetime -- acting as a reporter on a tremendous yacht, skimming its way along the Italian coast toward Cannes film festival, the most famous artists and movie stars of the day gathered to promote a new film. Of all the luminaries aboard -- an Italian ingénue, an American star, a reclusive director -- only one holds Hal in thrall: Stella. And while each has a past that belies the gilded surface, Stella has the most to hide. As Hal's obsession with Stella grows, he becomes determined to bring back the girl she once was, the girl who's been confined to history. An irresistibly entertaining and atmospheric novel set in some of the world's most glamorous locales, The Invitation is a sultry love story about the ways in which the secrets of the past stay with us -- no matter how much we try to escape them.

    Set in the wilds of Africa, Larger Than Life introduces Alice, the unforgettable character at the center of Picoult’s anticipated new novel, Leaving Time.   A researcher studying memory in elephants, Alice is fascinated by the bonds between mother and calf—the mother’s powerful protective instincts and her newborn’s unwavering loyalty. Living on a game reserve in Botswana, Alice is able to view the animals in their natural habitat—while following an important rule: She must only observe and never interfere. Then she finds an orphaned young elephant in the bush and cannot bear to leave the helpless baby behind. Thinking back on her own childhood, and on her shifting relationship with her mother, Alice risks her career to care for the calf. Yet what she comes to understand is the depth of a parent’s love.

    Diagnosed with MS, she awaits the results of another anxiety-inducing MRI. She’s just walked away from Connor, “a fixer” but possibly the love of her life. And nearing the holidays, the sights and sounds of winter in South Dakota only prick memories of better years gone by. Then, on a December morning at the university where she works, jarring gunshots pierce the halls. In a temporary safe place and terrified, Simone listens and pretends this will all be over soon.As she waits for silence, her mind racing, Simone’s past year comes into focus. Falling in love and missing it. Finding strength in family and enduring friendships. Planning for the future, fearing it, and hoping against hope in dark places. Her life has been changing at the speed of light, and each crossroad brought Simone here, to this day, to endure the things she can’t control and to confront those that she can.

    Now, back home in the Yorkshire moors, duty-bound to a blind father and an alcoholic brother, an ambitious Charlotte refuses to sink into hopelessness. With her sisters, Emily and Anne, Charlotte conceives a plan to earn money and pursue a dream: The Brontës will publish. In childhood the Brontë children created fantastical imaginary worlds; now the sisters craft novels quite unlike anything written before. Transforming her loneliness and personal sorrow into a triumph of literary art, Charlotte pens her 1847 masterpiece, Jane Eyre.Charlotte’s novel becomes an overwhelming literary success, catapulting the shy and awkward young woman into the spotlight of London’s fashionable literary scene—and into the arms of her new publisher, George Smith, an irresistibly handsome young man whose interest in his fiercely intelligent and spirited new author seems to go beyond professional duty. But just as life begins to hold new promise, unspeakable tragedy descends on the Brontë household, throwing London and George into the background and leaving Charlotte to fear that the only romance she will ever find is at the tip of her pen. But another man waits in the Brontës’ Haworth parsonage—the quiet but determined curate Arthur Nicholls. After secretly pining for Charlotte since he first came to work for her father, Arthur suddenly reveals his heart to her.Romancing Miss Brontë is a fascinating portrayal of an extraordinary woman whose life and work articulated our deepest human longing: to love and be loved in return.