They've heard everything from “My two-year-old gets constant ear infections. Should I give her antibiotics? Or probiotics?” to “I heard that my son’s asthma was caused by a lack of microbial exposure. Is this true, and if so what can I do about it now?”Google these questions, and you’ll be overwhelmed with answers. The internet is rife with speculation and misinformation about the risks and benefits of what most parents think of as simply germs, but which scientists now call the microbiome: the combined activity of all the tiny organisms inside our bodies and the surrounding environment that have an enormous impact on our health and well-being. Who better to turn to for answers than Drs. Gilbert and Knight, two of the top scientists leading the investigation into the microbiome—an investigation that is producing fascinating discoveries and bringing answers to parents who want to do the best for their young children. Dirt Is Good is a comprehensive, authoritative, accessible guide you've been searching for.

    Indeed, starting from this tiny, common speck, Jan Zalasiewicz offers readers a stimulating tour that begins with the Universe's dramatic birth in the unimaginable violence of the Big Bang and explores the construction of the Solar System and the origins of our own planet. Zalasiewicz shows the almost incredible complexity present in the apparently mundane pebble, starting with the astonishing number of atoms in each. We learn that many events in the Earth's ancient past can be deciphered from a pebble: volcanic eruptions; the lives and deaths of extinct animals and plants; the alien nature of long-vanished oceans; and even the creations of fool's gold and oil deep underground. Zalasiewicz also demonstrates how geologists reach deep into the Earth's past by forensic analysis of even the tiniest amounts of mineral matter. The pebble may be small, and ordinary, but it is also an eloquent part of our Earth's extraordinary, never-ending story.

    Using this example as a springboard, David M. Raup leaps into an egaging discussion of the theories, assumptions, and difficulties associated with the science of species extinction. Woven is along the way are stories of the trilobite eye, tropical reefs, flying reptiles, and the fate of the heath hen on Martha's Vineyard, a very modern extinction.

    It offers complete coverage of the basics of hematologic morphology, including examination of the peripheral blood smear, basic maturation of the blood cell lines, and discussions of a variety of clinical disorders. Over 400 photomicrographs, schematic diagrams, and electron micrographs visually clarify hematology from normal cell maturation to the development of various pathologies.Normal Newborn Peripheral Blood Morphology chapter covers the unique normal cells found in neonatal blood.A variety of high-quality schematic diagrams, photomicrographs, and electron micrographs visually reinforce your understanding of hematologic cellular morphology.Spiral binding and compact size make this book easy to use in a laboratory setting.Coverage of common cytochemical stains, along with a summary chart for interpretation, aids in classifying malignant and benign leukoproliferative disorders.Morphologic abnormalities are presented in chapters on erythrocytes and leukocytes, along with a schematic description of each cell, to provide correlations to various disease states.Body Fluids chapter covers the other fluids found in the body besides blood, using images from cytocentrifuged specimens.Updated information on the subtypes of chronic lymphocytic leukemia (CLL) helps you recognize variant forms of CLL you may encounter in the lab.

    People knew the basics: men and women had sex, and sometimes babies followed. But beyond that the origins of life were a colossal mystery. The Seeds of Life is the remarkable and rollicking story of how a series of blundering geniuses and brilliant amateurs struggled for two centuries to discover where, exactly, babies come from. Taking a page from investigative thrillers, acclaimed science writer Edward Dolnick looks to these early scientists as if they were detectives hot on the trail of a bedeviling and urgent mystery. These strange searchers included an Italian surgeon using shark teeth to prove that female reproductive organs were not 'failed' male genitalia, and a Catholic priest who designed ingenious miniature pants to prove that frogs required semen to fertilize their eggs. A witty and rousing history of science, The Seeds of Life presents our greatest scientists struggling-against their perceptions, their religious beliefs, and their deep-seated prejudices-to uncover how and where we come from.

    With the authority of a scholar and the sparkle of an old-time storyteller, Dr. Volney Steele takes the reader from rotgut whiskey to modern anesthetics, from castor oil to antibiotics, and from barroom surgery to modern hospital operations. Dr. Steele wrote Bleed, Blister, and Purge "to shed light on and celebrate the dedication and humanitarianism of those many physicians, nurses, shamans, and people of sound practical sense who saw their patients--often friends and family--through the adversities that bedeviled them."

    A writer for The New Yorker and The Atlantic Monthly, Carl Elliott ventures into the uncharted dark side of medicine, shining a light on the series of social and legislative changes that have sacrificed old-style doctoring to the values of consumer capitalism. Along the way, he introduces us to the often shifty characters who work the production line in Big Pharma: from the professional guinea pigs who test-pilot new drugs and the ghostwriters who pen “scientific” articles for drug manufacturers to the PR specialists who manufacture “news” bulletins. We meet the drug reps who will do practically anything to make quota in an ever-expanding arms race of pharmaceutical gift-giving; the “thought leaders” who travel the world to enlighten the medical community about the wonders of the latest release; even, finally, the ethicists who oversee all that commercialized medicine has to offer from their pharma-funded perches.   Taking the pulse of the medical community today, Elliott discovers the culture of deception that has become so institutionalized many people do not even see it as a problem. Head-turning stories and a rogue’s gallery of colorful characters become his springboard for exploring larger ethical issues surrounding money. Are there certain things that should not be bought and sold? In what ways do the ethics of business clash with the ethics of medical care? And what is wrong with medical consumerism anyway? Elliott asks all these questions and more as he examines the underbelly of medicine.

    Learning all the tongue twisting names, picking favorites based on ferocity, armor, or sheer size. For many kids this love of ‘terrible lizards’ fizzles out at some point between starting and leaving primary school. All those fancy names slowly forgotten, no longer any need for a favorite.For all those child dino fanatics who didn’t grow up to become paleontologists, dinosaurs seem like something out of mythology. They are dragons, pictures in books, abstract, other, extinct.They are at the same time familiar and mysterious. And yet we’re in an age of rapid discovery—new dinosaur species and genera are being discovered at an accelerating rate, we’re learning more about what they looked like, how they lived, how they evolved and where they all went.This series isn’t just a top trumps list of dino facts—we’re interested in the why and the how and like all areas of science there is plenty of controversy and debate.

    M. Kosemen and Dr. Darren NaishCryptozoologicon is a celebration of the myths, legends, evolution and biology of hidden animals. Always sceptical, but always willing to indulge in speculative fun, Cryptozoologicon aims to provide a new way to approach cryptozoology: as fictional biology.Cryptozoologicon will be available at all good digital retailers in early December.

    We get cancer because we can't avoid it—it's a bug in the system of life itself.Cancer exists in nearly every animal and has afflicted humans as long as our species has walked the earth. In Rebel Cell: Cancer, Evolution, and the New Science of Life's Oldest Betrayal, Kat Arney reveals the secrets of our most formidable medical enemy, most notably the fact that it isn't so much a foreign invader as a double agent: cancer is hardwired into the fundamental processes of life. New evidence shows that this disease is the result of the same evolutionary changes that allowed us to thrive. Evolution helped us outsmart our environment, and it helps cancer outsmart its environment as well—alas, that environment is us.Explaining why "everything we know about cancer is wrong," Arney, a geneticist and award-winning science writer, guides readers with her trademark wit and clarity through the latest research into the cellular mavericks that rebel against the rigid biological "society" of the body and make a leap towards anarchy.We need to be a lot smarter to defeat such a wily foe—smarter even than Darwin himself. In this new world, where we know that every cancer is unique and can evolve its way out of trouble, the old models of treatment have reached their limits. But we are starting to decipher cancer's secret evolutionary playbook, mapping the landscapes in which these rogue cells survive, thrive, or die, and using this knowledge to predict and confound cancer's next move.Rebel Cell is a story about life and death, hope and hubris, nature and nurture. It's about a new way of thinking about what this disease really is and the role it plays in human life. Above all, it's a story about where cancer came from, where it's going, and how we can stop it.